{"id":"https://openalex.org/W2186358548","doi":null,"title":"Antiphospholipid antibodies among women experiencing fetal loss.","display_name":"Antiphospholipid antibodies among women experiencing fetal loss.","publication_year":2013,"publication_date":"2013-12-01","ids":{"openalex":"https://openalex.org/W2186358548","mag":"2186358548","pmid":"https://pubmed.ncbi.nlm.nih.gov/24362478"},"language":"en","primary_location":{"id":"pmid:24362478","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24362478","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Malaysian journal of pathology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030793661","display_name":"Yee Ming Ching","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130795","display_name":"Institute for Medical Research","ror":"https://ror.org/03bpc5f92","country_code":"MY","type":"facility","lineage":["https://openalex.org/I4210130795"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Y M Ching","raw_affiliation_strings":["Allergy and Immunology Research Centre, Institute for Medical Research, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Allergy and Immunology Research Centre, Institute for Medical Research, Malaysia","institution_ids":["https://openalex.org/I4210130795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048307530","display_name":"Masita Arip","orcid":"https://orcid.org/0000-0001-5794-5134","observed_orcids":["https://orcid.org/0000-0001-5794-5134"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Arip","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068344155","display_name":"Ravindran Jegasothy","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Jegasothy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055357156","display_name":"T P Baskaran","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T P Baskaran","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027115035","display_name":"Ainuddin Yushar Yusof","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Y Yusof","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046589588","display_name":"F Bakhtiar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F Bakhtiar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5000219831","display_name":"Norlaila Mustafa","orcid":"https://orcid.org/0000-0002-0196-7091","observed_orcids":["https://orcid.org/0000-0002-0196-7091"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N Mustafa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2227,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.55648581,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"35","issue":"2","first_page":"147","last_page":"51"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antiphospholipid-antibodies","display_name":"antiphospholipid antibodies","score":1.0},{"id":"https://openalex.org/keywords/fetal-death","display_name":"fetal death","score":0.8939999938011169},{"id":"https://openalex.org/keywords/recurrent-pregnancy-loss","display_name":"recurrent pregnancy loss","score":0.8629999756813049},{"id":"https://openalex.org/keywords/miscarriage","display_name":"miscarriage","score":0.7080000042915344},{"id":"https://openalex.org/keywords/anticardiolipin-antibodies","display_name":"anticardiolipin antibodies","score":0.9760000109672546},{"id":"https://openalex.org/keywords/anti-beta2-glycoprotein-i-antibodies","display_name":"anti-beta2-glycoprotein I antibodies","score":0.8809999823570251},{"id":"https://openalex.org/keywords/antiphosphatidylserine-antibodies","display_name":"antiphosphatidylserine antibodies","score":0.9269999861717224},{"id":"https://openalex.org/keywords/preeclampsia","display_name":"preeclampsia","score":0.7570000290870667},{"id":"https://openalex.org/keywords/placental-insufficiency","display_name":"placental insufficiency","score":0.9340000152587891}],"concepts":[{"id":"https://openalex.org/C2777218350","wikidata":"https://www.wikidata.org/wiki/Q61335","display_name":"Preeclampsia","level":3,"score":0.7896133661270142},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.6926937103271484},{"id":"https://openalex.org/C2776874634","wikidata":"https://www.wikidata.org/wiki/Q582207","display_name":"Antiphospholipid syndrome","level":3,"score":0.6598783135414124},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6510000228881836},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.5766830444335938},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.555231511592865},{"id":"https://openalex.org/C2779637612","wikidata":"https://www.wikidata.org/wiki/Q2354337","display_name":"Phosphatidylserine","level":4,"score":0.5366119742393494},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.47501763701438904},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.47087109088897705},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.45364829897880554},{"id":"https://openalex.org/C2776886772","wikidata":"https://www.wikidata.org/wiki/Q2099138","display_name":"Placental insufficiency","level":5,"score":0.4278934597969055},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.4172879457473755},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.3477075397968292},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3376898765563965},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.335903525352478},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.22345054149627686},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1742112636566162},{"id":"https://openalex.org/C2778918659","wikidata":"https://www.wikidata.org/wiki/Q186915","display_name":"Phospholipid","level":3,"score":0.1690255105495453},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0630243718624115},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000022","descriptor_name":"Abortion, Spontaneous","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D000022","descriptor_name":"Abortion, Spontaneous","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008296","descriptor_name":"Malaysia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011248","descriptor_name":"Pregnancy Complications","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D011248","descriptor_name":"Pregnancy Complications","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D017152","descriptor_name":"Antibodies, Antiphospholipid","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:24362478","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24362478","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Malaysian journal of pathology","raw_type":"Journal Article"},{"id":"mag:2186358548","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24362478","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1594087679","https://openalex.org/W1926091065","https://openalex.org/W1975026254","https://openalex.org/W1988521312","https://openalex.org/W1990120810","https://openalex.org/W1997338829","https://openalex.org/W1999555834","https://openalex.org/W2000205521","https://openalex.org/W2005462660","https://openalex.org/W2040946163","https://openalex.org/W2049561149","https://openalex.org/W2054330426","https://openalex.org/W2070274041","https://openalex.org/W2101831374","https://openalex.org/W2115853654","https://openalex.org/W2164761163","https://openalex.org/W2164810820","https://openalex.org/W2169793480","https://openalex.org/W4322695715","https://openalex.org/W4323284207"],"related_works":["https://openalex.org/W2418467963","https://openalex.org/W7033879296","https://openalex.org/W2120617741","https://openalex.org/W2406541601","https://openalex.org/W7129062512","https://openalex.org/W2420778803","https://openalex.org/W2948898695","https://openalex.org/W2129940058","https://openalex.org/W2089945292","https://openalex.org/W1926091065"],"abstract_inverted_index":{"The":[0,156,180],"presence":[1,27],"of":[2,28,39,61,71,80,90,100,116,159,200],"antiphospholipid":[3],"antibodies":[4],"(aPLs)":[5],"is":[6],"closely":[7],"associated":[8],"with":[9,36,204,212],"thrombotic":[10],"events":[11],"and":[12,21,30,145,195],"pregnancy":[13,18],"complications":[14],"such":[15],"as":[16],"recurrent":[17],"loss,":[19],"preeclampsia":[20],"placental":[22,101],"insufficiency.":[23],"We":[24],"investigated":[25],"the":[26,68,87,113,150,218],"aPLs":[29,122,173,176,201],"its":[31],"frequency":[32,199],"among":[33,202],"female":[34],"patients":[35,52,160,164],"a":[37,43],"history":[38],"fetal":[40,205],"loss":[41,206],"in":[42,208],"Malaysia":[44,209],"population.":[45],"Serum":[46,118],"samples":[47],"were":[48,166,178],"collected":[49],"from":[50],"108":[51],"who":[53],"had":[54],"(1)":[55],"one":[56,75,172],"or":[57,66,73,76,85,95,97,103,106],"more":[58,77,107],"unexplained":[59],"deaths":[60],"morphologically":[62,81],"normal":[63,82],"fetuses":[64],"at":[65,84,170],"beyond":[67],"22nd":[69],"week":[70,89,115],"gestation,":[72],"(2)":[74],"premature":[78],"births":[79],"neonates":[83],"before":[86,112],"24th":[88],"gestation":[91],"due":[92],"to":[93],"eclampsia":[94],"preeclampsia,":[96],"recognized":[98],"features":[99],"insufficiency,":[102],"(3)":[104],"three":[105],"unexplained,":[108],"consecutive,":[109],"spontaneous":[110],"miscarriages":[111],"20th":[114],"gestation.":[117],"was":[119,161,184,210],"tested":[120],"for":[121,169],"subtypes:":[123],"anticardiolipin":[124],"(aCL),":[125],"anti-beta-2-":[126],"glycoprotein":[127],"I":[128,131],"(a\u03b22GPI),":[129],"anti-beta-2-glycoprotein":[130],"dependent":[132,135,186,215],"cardiolipin":[133],"(a\u03b22GPI":[134],"CL),":[136],"anti-phosphatidylcholine":[137],"(aPC),":[138],"anti-phosphatidylethanolamine":[139],"(aPE),":[140],"anti-phosphatidylinositol":[141],"(aPI),":[142],"anti-phosphatidylserine":[143],"(aPS)":[144],"anti-sphingomyeline":[146],"(aSph)":[147],"by":[148,190],"using":[149],"enzyme-linked":[151],"immunosorbent":[152],"assay":[153],"(ELISA)":[154],"method.":[155],"mean":[157],"age":[158],"30\u00b15.":[162],"Four":[163,175],"(3.7%)":[165,207],"found":[167],"positive":[168],"least":[171],"subtype.":[174],"subtypes":[177,183],"detected.":[179],"most":[181,219],"common":[182],"a\u03b22GPI":[185,193,214],"CL":[187,216],"(3.7%),":[188],"followed":[189],"aCL":[191],"(2.7%),":[192],"(0.9%),":[194],"aPE(0.9%).":[196],"In":[197],"conclusion,":[198],"women":[203],"low":[211],"subtype":[213],"being":[217],"prevalent":[220],"aPLs.":[221]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}