{"id":"https://openalex.org/W2186246336","doi":null,"title":"Escalated Oxidative Stress and Estrogen Level Stimulate Invasion of Tumor Cells in Infiltrating Ductal Carcinoma","display_name":"Escalated Oxidative Stress and Estrogen Level Stimulate Invasion of Tumor Cells in Infiltrating Ductal Carcinoma","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2186246336","mag":"2186246336"},"language":"en","primary_location":{"id":"mag:2186246336","doi":null,"is_oa":false,"landing_page_url":"https://globalresearchonline.net/journalcontents/v29-2/12.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Anirudh Nath","orcid":"https://orcid.org/0000-0001-8369-5159","observed_orcids":["https://orcid.org/0000-0001-8369-5159"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anirudh Nath","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8369-5159","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051052139","display_name":"Pallavi Priya","orcid":"https://orcid.org/0009-0007-5463-4673","observed_orcids":["https://orcid.org/0009-0007-5463-4673"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pallavi Priya","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013079705","display_name":"Aseem Kumar Anshu","orcid":"https://orcid.org/0000-0003-4878-0248","observed_orcids":["https://orcid.org/0000-0003-4878-0248"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aseem Kumar Anshu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4878-0248","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100675151","display_name":"Manisha Singh","orcid":"https://orcid.org/0000-0003-1983-4921","observed_orcids":["https://orcid.org/0000-0003-1983-4921","https://orcid.org/0000-0002-9453-5844"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Manisha Singh","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1983-4921","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009688563","display_name":"Richa Chauhan","orcid":"https://orcid.org/0000-0003-2405-3687","observed_orcids":["https://orcid.org/0000-0003-2405-3687"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Richa Chauhan","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2405-3687","affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"Jarnail Singh","orcid":"https://orcid.org/0000-0001-6032-2376","observed_orcids":["https://orcid.org/0000-0001-6032-2376"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jarnail Singh","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6032-2376","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14135","display_name":"Cancer and biochemical research","score":0.5151000022888184,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14135","display_name":"Cancer and biochemical research","score":0.5151000022888184,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.3441999852657318,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11134","display_name":"Breast Lesions and Carcinomas","score":0.055799998342990875,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/invasive-ductal-carcinoma","display_name":"invasive ductal carcinoma","score":0.9909999966621399},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.9760000109672546},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9980000257492065},{"id":"https://openalex.org/keywords/malondialdehyde","display_name":"malondialdehyde","score":0.9509999752044678},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.9440000057220459},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.9490000009536743},{"id":"https://openalex.org/keywords/estrogen","display_name":"estrogen","score":0.9819999933242798},{"id":"https://openalex.org/keywords/tumor-invasion","display_name":"tumor invasion","score":0.8790000081062317},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.7910000085830688},{"id":"https://openalex.org/keywords/postmenopausal-women","display_name":"postmenopausal women","score":0.859000027179718},{"id":"https://openalex.org/keywords/red-blood-cell-count","display_name":"red blood cell count","score":0.8309999704360962},{"id":"https://openalex.org/keywords/hemoglobin","display_name":"hemoglobin","score":0.8980000019073486}],"concepts":[{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7043275833129883},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.6123698949813843},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5886991024017334},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.5445066690444946},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.5052950978279114},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4934188425540924},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4661817252635956},{"id":"https://openalex.org/C16930146","wikidata":"https://www.wikidata.org/wiki/Q4381253","display_name":"Stromal cell","level":2,"score":0.4624721109867096},{"id":"https://openalex.org/C111683008","wikidata":"https://www.wikidata.org/wiki/Q1657620","display_name":"CA 15-3","level":5,"score":0.45465564727783203},{"id":"https://openalex.org/C2780862961","wikidata":"https://www.wikidata.org/wiki/Q5311598","display_name":"Ductal carcinoma","level":4,"score":0.4118579924106598},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3861149549484253},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.35783880949020386},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2997954189777374},{"id":"https://openalex.org/C118646709","wikidata":"https://www.wikidata.org/wiki/Q1657620","display_name":"CA15-3","level":4,"score":0.24292543530464172},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2186246336","doi":null,"is_oa":false,"landing_page_url":"https://globalresearchonline.net/journalcontents/v29-2/12.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W160409177","https://openalex.org/W1596855324","https://openalex.org/W1919092210","https://openalex.org/W1930327360","https://openalex.org/W1975650274","https://openalex.org/W1976920897","https://openalex.org/W1980385764","https://openalex.org/W1983310681","https://openalex.org/W1992808869","https://openalex.org/W1994442675","https://openalex.org/W1997816164","https://openalex.org/W2006998778","https://openalex.org/W2008931703","https://openalex.org/W2019745044","https://openalex.org/W2039921118","https://openalex.org/W2043862432","https://openalex.org/W2047518704","https://openalex.org/W2058965243","https://openalex.org/W2063598659","https://openalex.org/W2071748071","https://openalex.org/W2071904665","https://openalex.org/W2078288264","https://openalex.org/W2082709211","https://openalex.org/W2089803739","https://openalex.org/W2092171701","https://openalex.org/W2092561647","https://openalex.org/W2095424650","https://openalex.org/W2095719571","https://openalex.org/W2096528587","https://openalex.org/W2097388309","https://openalex.org/W2098002323","https://openalex.org/W2108361166","https://openalex.org/W2115775303","https://openalex.org/W2117149549","https://openalex.org/W2120395980","https://openalex.org/W2134850153","https://openalex.org/W2143261734","https://openalex.org/W2146538241","https://openalex.org/W2159696390","https://openalex.org/W2164837040","https://openalex.org/W2261427161","https://openalex.org/W2414792168"],"related_works":["https://openalex.org/W2893562366","https://openalex.org/W2063355741","https://openalex.org/W2160294993","https://openalex.org/W2333247962","https://openalex.org/W2939887077","https://openalex.org/W7217031578","https://openalex.org/W7099405066","https://openalex.org/W4415862013","https://openalex.org/W2052550114","https://openalex.org/W4307628786"],"abstract_inverted_index":{"Breast":[0],"cancer":[1,13,23,34,47,63,79,121],"(CaBr)":[2],"accredits":[3],"one":[4],"of":[5,9,20,33,45,61,85,90,101,111,113,158,168,244,250,256],"the":[6,17,21,42,233,242,254],"highest":[7,184],"numbers":[8],"deaths":[10],"due":[11,27],"to":[12,28,58,73,99,107,144,173,204],"in":[14,78,137,166,196,207],"women":[15],"on":[16],"planet.":[18],"Severity":[19],"breast":[22,46,62,251],"is":[24,41,82],"dreaded,":[25],"mostly":[26],"its":[29],"invasiveness":[30],"and":[31,48,125,139,149,187,210,236,252],"expedition":[32],"progression.":[35],"Since,":[36],"infiltrating":[37],"ductal":[38],"carcinoma":[39],"(IDC)":[40],"commonest":[43],"type":[44],"alone":[49],"accounts":[50],"for":[51,133],"more":[52,66],"than":[53,176,214],"80%":[54],"occurrence":[55],"as":[56,131,223],"compared":[57],"other":[59],"types":[60],"which":[64,240],"requires":[65],"focus.":[67],"Oxidative":[68],"stress":[69,231],"has":[70,104],"been":[71,105,129],"implicated":[72],"play":[74],"a":[75,83,88],"pivotal":[76],"role":[77],"development.":[80],"MDA":[81,124,135,164,195],"byproduct":[84],"lipid":[86],"peroxidation,":[87],"chain":[89],"reaction":[91],"initiated":[92],"by":[93,154,162],"reactive":[94],"oxygen":[95],"species":[96],"(ROS)":[97],"leading":[98],"death":[100],"cells.":[102],"Estrogen":[103],"reported":[106],"be":[108,174,205,227],"causative":[109],"agent":[110],"cancers":[112],"epithelial":[114,119,245],"origin":[115],"including":[116],"IDC,":[117],"mullerian":[118],"ovarian":[120],"etc.":[122],"Thus,":[123],"estrogen":[126,159,237],"levels":[127],"have":[128],"selected":[130],"biomarker":[132],"IDC.":[134,257],"assessment":[136],"serum":[138,167],"tissue":[140,197],"was":[141,160,171,191,202],"performed":[142,161],"according":[143],"standard":[145,155],"protocol.":[146,156],"RBC":[147,200],"count":[148,201],"haemoglobin":[150],"level":[151,165,185,218,222],"were":[152],"measured":[153],"Estimation":[157],"ELISA.":[163],"CaBr":[169,181,212],"patients":[170,182,213],"found":[172],"higher":[175],"normal":[177,215],"persons":[178],"with":[179,198],"postmenopausal":[180,211],"having":[183],"(p<0.0001)":[186],"similar":[188,221],"fashioned":[189],"graph":[190],"established":[192],"while":[193],"analyzing":[194],"p<0.0493.":[199],"observed":[203],"lower":[206],"both":[208],"premenopausal":[209],"person,":[216],"Haemoglobin":[217],"also":[219],"shows":[220],"RBC.":[224],"It":[225],"can":[226],"concluded":[228],"that":[229],"oxidative":[230],"devastate":[232],"cells":[234,246,249],"structure":[235],"enhances":[238],"proliferation":[239],"induces":[241],"invasion":[243],"into":[247],"stromal":[248],"begins":[253],"formation":[255]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}