{"id":"https://openalex.org/W2185477164","doi":null,"title":"Single nucleotide polymorphism in exon of ApoE receptor 2 gene associated with dyslipidemia in a Thai population","display_name":"Single nucleotide polymorphism in exon of ApoE receptor 2 gene associated with dyslipidemia in a Thai population","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2185477164","mag":"2185477164"},"language":"en","primary_location":{"id":"mag:2185477164","doi":null,"is_oa":false,"landing_page_url":"http://www.isaet.org/images/extraimages/IJCEBS%200101105.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089765200","display_name":"Polphet Thongket","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Polphet Thongket","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020675092","display_name":"Siriporn Chatsuriyawong","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Siriporn Chatsuriyawong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5057651404","display_name":"Wasana Sukhumsirichart","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wasana Sukhumsirichart","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.8090999722480774,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.8090999722480774,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.12470000237226486,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.04809999838471413,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.9200000166893005},{"id":"https://openalex.org/keywords/apoer2","display_name":"ApoER2","score":0.9399999976158142},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9789999723434448},{"id":"https://openalex.org/keywords/genetic-association","display_name":"genetic association","score":0.7919999957084656},{"id":"https://openalex.org/keywords/serum-lipids","display_name":"serum lipids","score":0.6690000295639038},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.9139999747276306},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.9959999918937683},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.8640000224113464},{"id":"https://openalex.org/keywords/total-cholesterol","display_name":"total cholesterol","score":0.8920000195503235},{"id":"https://openalex.org/keywords/thai-population","display_name":"Thai population","score":0.9179999828338623}],"concepts":[{"id":"https://openalex.org/C2778096610","wikidata":"https://www.wikidata.org/wiki/Q1476525","display_name":"Dyslipidemia","level":3,"score":0.7975364923477173},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.6967025995254517},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5663424730300903},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.5486281514167786},{"id":"https://openalex.org/C2780948078","wikidata":"https://www.wikidata.org/wiki/Q21130010","display_name":"PCSK9","level":5,"score":0.5255045890808105},{"id":"https://openalex.org/C31467283","wikidata":"https://www.wikidata.org/wiki/Q912147","display_name":"Genotyping","level":4,"score":0.5184676051139832},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.49450966715812683},{"id":"https://openalex.org/C62746215","wikidata":"https://www.wikidata.org/wiki/Q14890615","display_name":"Apolipoprotein B","level":3,"score":0.4540276825428009},{"id":"https://openalex.org/C57089818","wikidata":"https://www.wikidata.org/wiki/Q424728","display_name":"Apolipoprotein E","level":3,"score":0.44561246037483215},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4328981041908264},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4321008324623108},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.4262217879295349},{"id":"https://openalex.org/C2780541478","wikidata":"https://www.wikidata.org/wiki/Q410020","display_name":"High-density lipoprotein","level":3,"score":0.41914334893226624},{"id":"https://openalex.org/C139572402","wikidata":"https://www.wikidata.org/wiki/Q4927820","display_name":"Blood lipids","level":3,"score":0.41238224506378174},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.38615676760673523},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3773614168167114},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.3543815612792969},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.34885090589523315},{"id":"https://openalex.org/C43554185","wikidata":"https://www.wikidata.org/wiki/Q425649","display_name":"LDL receptor","level":4,"score":0.2784169614315033},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2089160680770874},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.13874602317810059},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2185477164","doi":null,"is_oa":false,"landing_page_url":"http://www.isaet.org/images/extraimages/IJCEBS%200101105.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1488147530","https://openalex.org/W1576642143","https://openalex.org/W1849327488","https://openalex.org/W1967439374","https://openalex.org/W2044514969","https://openalex.org/W2051394059","https://openalex.org/W2071759640","https://openalex.org/W2105281057","https://openalex.org/W2129327581","https://openalex.org/W2145469603","https://openalex.org/W2146153473","https://openalex.org/W2161527180","https://openalex.org/W4299843823"],"related_works":["https://openalex.org/W2993217379","https://openalex.org/W119910844","https://openalex.org/W1416304121","https://openalex.org/W185617325","https://openalex.org/W2103727072","https://openalex.org/W7132041258","https://openalex.org/W4213309245","https://openalex.org/W2106277085","https://openalex.org/W7133034125","https://openalex.org/W2429318974"],"abstract_inverted_index":{"Dyslipidemia":[0],"is":[1,11,211],"an":[2],"abnormal":[3],"amount":[4],"of":[5,16,35,54,73,92,107,178,200,217,223],"lipid":[6,39,119],"in":[7,44,71,86,115,166,190,202,220,230],"the":[8,42,51,66,69,74,116,133,179,188,191,198,203,215,224],"blood.":[9],"It":[10,24],"a":[12,87],"major":[13],"risk":[14,199],"factor":[15],"atherosclerosis,":[17],"cardiovascular":[18],"disease,":[19],"and":[20,28,38,63,99,109,127,137,159,171],"coronary":[21],"heart":[22],"disease.":[23],"cause":[25],"by":[26,175],"environment":[27],"genetic":[29,218],"factors.":[30],"A":[31,90],"genome-wide":[32],"association":[33,83,196],"study":[34,117,210],"blood":[36,146],"lipoprotein":[37,56,60],"revealed":[40,186],"that":[41,187],"SNPs":[43,70],"apolipoprotein":[45],"E":[46],"(ApoE)":[47],"gene":[48,79],"associated":[49],"with":[50,84,104,197],"high":[52],"level":[53,120],"low-density":[55],"cholesterol":[57,61],"(LDL-C),":[58],"high-density":[59],"(HDL-C)":[62],"triglyceride.":[64],"In":[65],"present":[67],"study,":[68],"exon":[72],"ApoE":[75],"receptor":[76],"2":[77],"(ApoER2)":[78],"was":[80,154,173],"analyzed":[81],"for":[82,213],"dyslipidemia":[85,97,201],"Thai":[88,204],"population.":[89],"total":[91,124],"400":[93],"subjects":[94,134],"including":[95],"200":[96,100],"patients":[98],"unrelated":[101],"normal":[102],"controls":[103],"mean":[105],"age":[106],"47.01\u00b10.5":[108],"47.91\u00b10.5":[110],"years,":[111],"respectively,":[112],"were":[113,142],"participated":[114],"using":[118,147,156],"such":[121],"as":[122,129],"triglyceride,":[123],"cholesterol,":[125],"LDL-C,":[126],"HDL-C":[128],"criteria":[130],"to":[131],"allocate":[132],"into":[135],"control":[136,172],"patient":[138,170],"groups.":[139],"The":[140,164,184],"DNAs":[141],"extracted":[143],"from":[144],"whole":[145],"Flexigene":[148],"DNA":[149],"kit":[150],"(QIAGEN,":[151],"German).":[152],"Genotyping":[153],"performed":[155],"real-time":[157],"PCR":[158],"high-resolution":[160],"melting":[161],"(HRM)":[162],"analysis.":[163],"difference":[165],"genotype":[167],"distribution":[168],"between":[169],"assessed":[174],"Chi-square":[176],"test":[177],"SPSS":[180],"software":[181],"version":[182],"11.5.":[183],"result":[185],"SNP":[189],"ApoER2,":[192],"rs3737983,":[193],"showed":[194],"significant":[195],"population":[205],"(P-value":[206],"=":[207],"0.011).":[208],"Further":[209],"required":[212],"clarification":[214],"role":[216],"variation":[219],"expression":[221],"pattern":[222],"ApoER2":[225],"which":[226],"may":[227],"be":[228],"involved":[229],"dyslipidemia.":[231]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}