{"id":"https://openalex.org/W2185046622","doi":null,"title":"Pomegranate Flower Complex a Novel Anti-ageing Active","display_name":"Pomegranate Flower Complex a Novel Anti-ageing Active","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2185046622","mag":"2185046622"},"language":"en","primary_location":{"id":"mag:2185046622","doi":null,"is_oa":false,"landing_page_url":"http://www.lipoid-kosmetik.com/sites/default/files/files/Publikation%20-%20CST%202013%20Pomegranate%20Flower(1).pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040179675","display_name":"J. M. Smits","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Smits","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5006814870","display_name":"N. Herbst","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N. Herbst","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11013","display_name":"Skin Protection and Aging","score":0.8213000297546387,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11013","display_name":"Skin Protection and Aging","score":0.8213000297546387,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12638","display_name":"Pomegranate: compositions and health benefits","score":0.17649999260902405,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/skin-aging","display_name":"skin aging","score":0.9679999947547913},{"id":"https://openalex.org/keywords/collagen-synthesis","display_name":"collagen synthesis","score":0.6990000009536743},{"id":"https://openalex.org/keywords/collagen-degradation","display_name":"collagen degradation","score":0.6669999957084656},{"id":"https://openalex.org/keywords/mmp-1","display_name":"MMP-1","score":0.902999997138977},{"id":"https://openalex.org/keywords/uva-irradiation","display_name":"UVA irradiation","score":0.75},{"id":"https://openalex.org/keywords/dermal-fibroblasts","display_name":"dermal fibroblasts","score":0.9279999732971191},{"id":"https://openalex.org/keywords/skin-wrinkles","display_name":"wrinkles","score":0.6819999814033508},{"id":"https://openalex.org/keywords/skin-density","display_name":"skin density","score":0.8090000152587891},{"id":"https://openalex.org/keywords/botanical-ingredients","display_name":"botanical ingredients","score":0.5429999828338623}],"concepts":[{"id":"https://openalex.org/C500499127","wikidata":"https://www.wikidata.org/wiki/Q332154","display_name":"Ageing","level":2,"score":0.8614093065261841},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.6449092030525208},{"id":"https://openalex.org/C2909910311","wikidata":"https://www.wikidata.org/wiki/Q5259911","display_name":"Skin Aging","level":2,"score":0.6211901903152466},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.596521258354187},{"id":"https://openalex.org/C2777459323","wikidata":"https://www.wikidata.org/wiki/Q5259911","display_name":"Human skin","level":2,"score":0.4645281732082367},{"id":"https://openalex.org/C109523444","wikidata":"https://www.wikidata.org/wiki/Q424216","display_name":"Matrix metalloproteinase","level":2,"score":0.44173863530158997},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4259885549545288},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.41547057032585144},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.36763668060302734},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.3200226426124573},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19954553246498108},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.16393917798995972},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.1568460762500763},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1295645833015442},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2185046622","doi":null,"is_oa":false,"landing_page_url":"http://www.lipoid-kosmetik.com/sites/default/files/files/Publikation%20-%20CST%202013%20Pomegranate%20Flower(1).pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6240000128746033,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":5,"referenced_works":["https://openalex.org/W1988332584","https://openalex.org/W2017517432","https://openalex.org/W2114273795","https://openalex.org/W2165476613","https://openalex.org/W2423907343"],"related_works":["https://openalex.org/W2503456996","https://openalex.org/W4206230092","https://openalex.org/W2009934412","https://openalex.org/W4402104174","https://openalex.org/W2030491555","https://openalex.org/W7132847725","https://openalex.org/W2413884547","https://openalex.org/W3162666640","https://openalex.org/W4404471775","https://openalex.org/W2053931718"],"abstract_inverted_index":{"This":[0],"multi-active":[1],"complex":[2],"based":[3],"on":[4,91],"pomegranate":[5,146,164],"flowers":[6,147],"was":[7,140,168,197],"developed":[8],"to":[9,24,59,67,200,206],"address":[10],"the":[11,26,37,44,62,71,83,92,105,111,119,126,130],"growing":[12],"demand":[13],"for":[14,129],"botanical-based":[15],"anti-ageing":[16],"actives.":[17],"It":[18,69,139],"is":[19,43,57,70,134],"a":[20,79,108,176,182,189],"multi-functional":[21],"active":[22],"designed":[23],"reduce":[25],"visible":[27],"signs":[28],"of":[29,39,46,85,113,122,125,132,145,178,217],"ageing":[30,42,52],"by":[31],"increasing":[32],"skin":[33,86,93,223],"density":[34],"and":[35,53,94,103,157,181,185,205,213,220],"decreasing":[36],"appearance":[38,121],"wrinkles.":[40,123],"Skin":[41],"result":[45],"two":[47,75],"processes,":[48],"intrinsic":[49],"or":[50],"chronological":[51],"extrinsic":[54],"ageing,":[55],"which":[56,77,116],"due":[58],"environmental":[60],"factors,":[61],"most":[63],"important":[64],"being":[65],"exposure":[66],"UV.":[68],"balance":[72],"between":[73],"these":[74],"processes":[76,96],"plays":[78],"crucial":[80],"role":[81],"in":[82,100,110,118,154,211,222],"process":[84],"ageing.":[87],"Environmental":[88],"factors":[89],"acting":[90],"genetically-determined":[95],"cause":[97],"an":[98,143],"increase":[99,221],"collagen":[101,133,186,203],"breakdown":[102,131,209],"at":[104],"same":[106],"time":[107],"reduction":[109],"synthesis":[112,204],"new":[114],"collagen,":[115],"results":[117],"increased":[120],"One":[124],"enzymes":[127],"responsible":[128],"matrix":[135],"metalloproteinase":[136],"1":[137],"(MMP-1).":[138],"demonstrated":[141],"that":[142],"extract":[144,166],"(PGFE)":[148,167],"reduced":[149,215],"MMP-1":[150],"mRNA":[151],"gene":[152],"expression":[153],"UVA":[155],"irradiated":[156],"non-irradiated":[158],"primary":[159],"human":[160],"dermal":[161],"fibroblasts.":[162],"The":[163,193],"flower":[165],"then":[169],"combined":[170,194],"with":[171],"sodium":[172],"ascorbyl":[173],"phosphate":[174],"(SAP),":[175],"derivative":[177],"vitamin":[179],"C":[180],"well-known":[183],"antioxidant":[184],"booster,":[187],"into":[188],"single":[190],"product":[191,195],"(PGFE/SAP).":[192],"(PGFE/SAP)":[196],"shown":[198],"both":[199],"successfully":[201],"promote":[202],"inhibit":[207],"its":[208],"resulting":[210],"measurably":[212],"visibly":[214],"depth":[216],"facial":[218],"wrinkles":[219],"density.":[224]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}