{"id":"https://openalex.org/W2185035241","doi":"https://doi.org/10.18553/jmcp.2002.8.4.259","title":"Neuroleptic Drug Exposure and Incidence of Tardive Dyskinesia: A Records-based Case-Control Study","display_name":"Neuroleptic Drug Exposure and Incidence of Tardive Dyskinesia: A Records-based Case-Control Study","publication_year":2002,"publication_date":"2002-07-01","ids":{"openalex":"https://openalex.org/W2185035241","doi":"https://doi.org/10.18553/jmcp.2002.8.4.259","mag":"2185035241","pmid":"https://pubmed.ncbi.nlm.nih.gov/14613418"},"language":"en","primary_location":{"id":"doi:10.18553/jmcp.2002.8.4.259","doi":"https://doi.org/10.18553/jmcp.2002.8.4.259","is_oa":false,"landing_page_url":"https://doi.org/10.18553/jmcp.2002.8.4.259","pdf_url":null,"source":{"id":"https://openalex.org/S40961437","display_name":"Journal of Managed Care Pharmacy","issn_l":"1083-4087","issn":["1083-4087","1944-706X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1"],"host_organization":"https://openalex.org/P4363609268","host_organization_name":"Academy of Managed Care Pharmacy","host_organization_lineage":["https://openalex.org/P4363609268"],"host_organization_lineage_names":["Academy of Managed Care Pharmacy"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Managed Care Pharmacy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065624201","display_name":"D.L. Marshall","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Donna L. Marshall","raw_affiliation_strings":["Marshall RX Consultants, Inc., Renton, WA 98058, USA. donnamarshall@qwest.net","Clinical Associate Professor, University of Washington, Department of Pharmacy, Seattle, Washington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marshall RX Consultants, Inc., Renton, WA 98058, USA. donnamarshall@qwest.net","institution_ids":[]},{"raw_affiliation_string":"Clinical Associate Professor, University of Washington, Department of Pharmacy, Seattle, Washington","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064343267","display_name":"Thomas K. Hazlet","orcid":"https://orcid.org/0000-0001-5606-1417","observed_orcids":["https://orcid.org/0000-0001-5606-1417"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas K. Hazlet","raw_affiliation_strings":["Clinical Associate Professor, University of Washington, Department of Pharmacy, Seattle, Washington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Associate Professor, University of Washington, Department of Pharmacy, Seattle, Washington","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019200269","display_name":"Jacqueline S. Gardner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jacqueline S. Gardner","raw_affiliation_strings":["Inc., Renton, Washington;","Marshall RX Consultants, Inc., 18601 173rd Way S.E., Renton, WA 98058","University of Washington, Department of Pharmacy, Seattle, Washington;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inc., Renton, Washington;","institution_ids":[]},{"raw_affiliation_string":"Marshall RX Consultants, Inc., 18601 173rd Way S.E., Renton, WA 98058","institution_ids":[]},{"raw_affiliation_string":"University of Washington, Department of Pharmacy, Seattle, Washington;","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037856690","display_name":"David King Blough","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David K. Blough","raw_affiliation_strings":["Inc., Renton, Washington;","Marshall RX Consultants, Inc., 18601 173rd Way S.E., Renton, WA 98058","University of Washington, Department of Pharmacy, Seattle, Washington;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inc., Renton, Washington;","institution_ids":[]},{"raw_affiliation_string":"Marshall RX Consultants, Inc., 18601 173rd Way S.E., Renton, WA 98058","institution_ids":[]},{"raw_affiliation_string":"University of Washington, Department of Pharmacy, Seattle, Washington;","institution_ids":["https://openalex.org/I201448701"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5065624201"],"corresponding_institution_ids":["https://openalex.org/I201448701"],"apc_list":null,"apc_paid":null,"fwci":0.2138,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.61401395,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"8","issue":"4","first_page":"259","last_page":"265"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11921","display_name":"Electroconvulsive Therapy Studies","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12666","display_name":"Historical Psychiatry and Medical Practices","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tardive-dyskinesia","display_name":"tardive dyskinesia","score":1.0},{"id":"https://openalex.org/keywords/antipsychotic-drugs","display_name":"antipsychotic drugs","score":0.75},{"id":"https://openalex.org/keywords/atypical-antipsychotics","display_name":"atypical antipsychotics","score":0.968999981880188},{"id":"https://openalex.org/keywords/typical-antipsychotics","display_name":"typical antipsychotics","score":0.9399999976158142},{"id":"https://openalex.org/keywords/drug-induced-movement-disorders","display_name":"drug-induced movement disorders","score":0.6589999794960022},{"id":"https://openalex.org/keywords/veterans","display_name":"veterans","score":0.7900000214576721},{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.7160000205039978},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.39500001072883606},{"id":"https://openalex.org/keywords/antiparkinsonian-drugs","display_name":"antiparkinsonian drugs","score":0.7369999885559082}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8648443222045898},{"id":"https://openalex.org/C2779158372","wikidata":"https://www.wikidata.org/wiki/Q1546328","display_name":"Tardive dyskinesia","level":3,"score":0.8526614904403687},{"id":"https://openalex.org/C195910791","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Medical record","level":2,"score":0.592265248298645},{"id":"https://openalex.org/C2781204524","wikidata":"https://www.wikidata.org/wiki/Q2802443","display_name":"Diagnosis of schizophrenia","level":3,"score":0.5468603372573853},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.538270115852356},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.5247933268547058},{"id":"https://openalex.org/C2780405171","wikidata":"https://www.wikidata.org/wiki/Q629444","display_name":"Dyskinesia","level":4,"score":0.49374112486839294},{"id":"https://openalex.org/C2780325297","wikidata":"https://www.wikidata.org/wiki/Q834047","display_name":"Schizoaffective disorder","level":3,"score":0.4690675437450409},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.453810453414917},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.44958096742630005},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4288364350795746},{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.41028642654418945},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.38755202293395996},{"id":"https://openalex.org/C2779727114","wikidata":"https://www.wikidata.org/wiki/Q170082","display_name":"Psychosis","level":2,"score":0.3692924380302429},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.26577845215797424},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.07704749703407288},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.18553/jmcp.2002.8.4.259","doi":"https://doi.org/10.18553/jmcp.2002.8.4.259","is_oa":false,"landing_page_url":"https://doi.org/10.18553/jmcp.2002.8.4.259","pdf_url":null,"source":{"id":"https://openalex.org/S40961437","display_name":"Journal of Managed Care Pharmacy","issn_l":"1083-4087","issn":["1083-4087","1944-706X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1"],"host_organization":"https://openalex.org/P4363609268","host_organization_name":"Academy of Managed Care Pharmacy","host_organization_lineage":["https://openalex.org/P4363609268"],"host_organization_lineage_names":["Academy of Managed Care Pharmacy"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Managed Care Pharmacy","raw_type":"journal-article"},{"id":"pmid:14613418","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14613418","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of managed care pharmacy : JMCP","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.465.3231","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.465.3231","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.amcp.org/data/jmcp/Research-259-265.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7900000214576721}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1545946068","https://openalex.org/W1812726166","https://openalex.org/W1847831565","https://openalex.org/W1964855006","https://openalex.org/W1983133139","https://openalex.org/W2010639428","https://openalex.org/W2019115177","https://openalex.org/W2028898880","https://openalex.org/W2035560842","https://openalex.org/W2060859917","https://openalex.org/W2067570375","https://openalex.org/W2069517705","https://openalex.org/W2077953681","https://openalex.org/W2131758418","https://openalex.org/W2133278878","https://openalex.org/W2165743028","https://openalex.org/W2412626412","https://openalex.org/W3027453416","https://openalex.org/W3027735042","https://openalex.org/W3151757975","https://openalex.org/W3204455779","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W1965171213","https://openalex.org/W2468665302","https://openalex.org/W2029977125","https://openalex.org/W1770151777","https://openalex.org/W1995979185","https://openalex.org/W2418838817","https://openalex.org/W2989664537","https://openalex.org/W2298144227","https://openalex.org/W2052352110","https://openalex.org/W2020676501"],"abstract_inverted_index":{"BACKGROUND:":[0],"With":[1],"the":[2,9,11,20,29,41,59,76,127,140,156,161,171,182,230],"introduction":[3],"of":[4,13,22,35,43,58,118,129,152,173,210,232,236,241],"atypical":[5,30,49,183,242],"neuroleptic":[6,73,88,119,184],"medications":[7,74],"into":[8],"marketplace,":[10],"use":[12],"conventional":[14,51,178,237],"neuroleptics":[15,179,238],"has":[16],"fallen,":[17],"attendant":[18],"with":[19,48],"perception":[21],"a":[23,116,149,225],"more":[24],"favorable":[25],"side-effect":[26],"profile":[27],"for":[28,72,94,139,175,191,234],"neuroleptics.":[31,52,243],"OBJECTIVE:":[32],"The":[33,123,143],"purpose":[34],"this":[36],"study":[37,77,221],"was":[38,126,148,166,203],"to":[39,86,104,160,181],"determine":[40],"risk":[42,172,209,231],"tardive":[44],"dyskinesia":[45],"(TD)":[46],"associated":[47],"and":[50,81,96,136,199,214],"METHODS:":[53],"Subjects":[54],"were":[55,84,102,112,133],"adult":[56],"users":[57,120,185,235,240],"Veterans":[60],"Administration":[61],"Puget":[62],"Sound":[63],"Health":[64],"Care":[65],"System":[66],"(VA-PSHCS)":[67],"who":[68],"received":[69],">or=1":[70],"prescription":[71],"during":[75],"period.":[78],"Electronic":[79],"medical":[80],"pharmacy":[82],"records":[83,101],"used":[85],"obtain":[87],"drug":[89],"exposure,":[90],"exclusionary":[91],"diagnosis,":[92],"diagnosis":[93,128],"TD,":[95],"select":[97],"demographic":[98,106,145],"data.":[99],"Medical":[100],"reviewed":[103],"collect":[105],"data":[107],"not":[108,223],"available":[109],"electronically.":[110],"Controls":[111],"randomly":[113],"selected":[114],"from":[115],"cohort":[117],"without":[121],"TD.":[122,130],"case-defining":[124],"event":[125],"RESULTS:":[131],"There":[132,165],"42":[134],"cases":[135,213],"160":[137],"controls":[138,215],"final":[141],"analysis.":[142],"only":[144],"difference":[146,169,207,228],"found":[147],"higher":[150],"proportion":[151],"Caucasians":[153],"(90%)":[154],"in":[155,170,208,229],"TD":[157,174,211,233],"group":[158,163],"compared":[159,180],"control":[162],"(76%).":[164],"no":[167,205],"significant":[168,206,227],"patients":[176],"on":[177],"(OR=1.29;":[186],"95%":[187,217],"CI=0.71-2.34).":[188],"After":[189],"adjusting":[190],"age,":[192],"gender,":[193],"race,":[194],"schizophrenia,":[195],"schizoaffective":[196],"disorder,":[197],"depression,":[198],"anti-Parkinson":[200],"drugs,":[201],"there":[202],"still":[204],"between":[212],"(OR=1.02;":[216],"CI=0.465-2.232).":[218],"CONCLUSION:":[219],"This":[220],"did":[222],"find":[224],"statistically":[226],"versus":[239]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}