{"id":"https://openalex.org/W2184993140","doi":null,"title":"DIABETIC NEPHROPATHY- PATHOGENESIS AND NEWER TARGETS IN TREATMENT Review Article","display_name":"DIABETIC NEPHROPATHY- PATHOGENESIS AND NEWER TARGETS IN TREATMENT Review Article","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2184993140","mag":"2184993140"},"language":"en","primary_location":{"id":"mag:2184993140","doi":null,"is_oa":false,"landing_page_url":"http://globalresearchonline.net/journalcontents/volume6issue2/article-017.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075097419","display_name":"Hemanth Kumar","orcid":"https://orcid.org/0000-0003-0565-5615","observed_orcids":["https://orcid.org/0000-0003-0565-5615"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hemanth Kumar","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0565-5615","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5019604905","display_name":"Vidya Sagar J","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Vidya Sagar J","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diabetic-nephropathy","display_name":"diabetic nephropathy","score":1.0},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.949999988079071},{"id":"https://openalex.org/keywords/microalbuminuria","display_name":"microalbuminuria","score":0.9200000166893005},{"id":"https://openalex.org/keywords/end-stage-renal-disease","display_name":"end-stage renal disease","score":0.9850000143051147},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.9879999756813049},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.781000018119812},{"id":"https://openalex.org/keywords/blood-pressure-control","display_name":"blood pressure control","score":0.9990000128746033},{"id":"https://openalex.org/keywords/renin-angiotensin-system-blockade","display_name":"renin-angiotensin system blockade","score":0.859000027179718},{"id":"https://openalex.org/keywords/antihypertensive-drugs","display_name":"antihypertensive drugs","score":0.9440000057220459},{"id":"https://openalex.org/keywords/intraglomerular-pressure","display_name":"intraglomerular pressure","score":0.8960000276565552},{"id":"https://openalex.org/keywords/lipid-management","display_name":"lipid control","score":0.5870000123977661},{"id":"https://openalex.org/keywords/disease-progression","display_name":"disease progression","score":0.7860000133514404}],"concepts":[{"id":"https://openalex.org/C2781203188","wikidata":"https://www.wikidata.org/wiki/Q1676817","display_name":"Microalbuminuria","level":3,"score":0.9535857439041138},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7848905920982361},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.7608380913734436},{"id":"https://openalex.org/C2779922275","wikidata":"https://www.wikidata.org/wiki/Q1129105","display_name":"Diabetic nephropathy","level":3,"score":0.7108582854270935},{"id":"https://openalex.org/C2781184683","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Nephropathy","level":3,"score":0.6127566695213318},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5693237781524658},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.5643399953842163},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5414453148841858},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4677092432975769},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.38481688499450684},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.36961525678634644},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3616557717323303},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.35748010873794556},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.30898261070251465}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2184993140","doi":null,"is_oa":false,"landing_page_url":"http://globalresearchonline.net/journalcontents/volume6issue2/article-017.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":156,"referenced_works":["https://openalex.org/W1676536","https://openalex.org/W76204639","https://openalex.org/W122369139","https://openalex.org/W165549381","https://openalex.org/W820854987","https://openalex.org/W1503258737","https://openalex.org/W1527011538","https://openalex.org/W1547902391","https://openalex.org/W1594856996","https://openalex.org/W1649363252","https://openalex.org/W1737796001","https://openalex.org/W1752750900","https://openalex.org/W1963775609","https://openalex.org/W1963864987","https://openalex.org/W1964448491","https://openalex.org/W1964920299","https://openalex.org/W1964997570","https://openalex.org/W1967172766","https://openalex.org/W1971823155","https://openalex.org/W1971950787","https://openalex.org/W1973766585","https://openalex.org/W1974824856","https://openalex.org/W1976070473","https://openalex.org/W1978240469","https://openalex.org/W1983206326","https://openalex.org/W1983678974","https://openalex.org/W1989737081","https://openalex.org/W1990805809","https://openalex.org/W1991539870","https://openalex.org/W1991595901","https://openalex.org/W1997676435","https://openalex.org/W1998378885","https://openalex.org/W1998967864","https://openalex.org/W2003091346","https://openalex.org/W2005103084","https://openalex.org/W2005502601","https://openalex.org/W2008010521","https://openalex.org/W2008990233","https://openalex.org/W2010818019","https://openalex.org/W2011211981","https://openalex.org/W2011557080","https://openalex.org/W2014461731","https://openalex.org/W2017311910","https://openalex.org/W2018970541","https://openalex.org/W2019253922","https://openalex.org/W2021173605","https://openalex.org/W2021722695","https://openalex.org/W2023126647","https://openalex.org/W2023362855","https://openalex.org/W2023367990","https://openalex.org/W2027366537","https://openalex.org/W2031085640","https://openalex.org/W2033391106","https://openalex.org/W2035313919","https://openalex.org/W2040405167","https://openalex.org/W2040961193","https://openalex.org/W2041391173","https://openalex.org/W2043362010","https://openalex.org/W2043828707","https://openalex.org/W2044437167","https://openalex.org/W2046303127","https://openalex.org/W2047964022","https://openalex.org/W2048393160","https://openalex.org/W2049276892","https://openalex.org/W2050220173","https://openalex.org/W2051616579","https://openalex.org/W2060423078","https://openalex.org/W2061202476","https://openalex.org/W2062273929","https://openalex.org/W2062335942","https://openalex.org/W2062862675","https://openalex.org/W2066685054","https://openalex.org/W2066888615","https://openalex.org/W2067297750","https://openalex.org/W2067679923","https://openalex.org/W2069246794","https://openalex.org/W2070474257","https://openalex.org/W2073549750","https://openalex.org/W2073876685","https://openalex.org/W2075271694","https://openalex.org/W2075862427","https://openalex.org/W2076422702","https://openalex.org/W2077498612","https://openalex.org/W2077811405","https://openalex.org/W2080505183","https://openalex.org/W2083133993","https://openalex.org/W2083826829","https://openalex.org/W2085148802","https://openalex.org/W2087367592","https://openalex.org/W2088985230","https://openalex.org/W2091031177","https://openalex.org/W2091754751","https://openalex.org/W2093601206","https://openalex.org/W2093840384","https://openalex.org/W2094128910","https://openalex.org/W2096127054","https://openalex.org/W2097760859","https://openalex.org/W2100990796","https://openalex.org/W2101417448","https://openalex.org/W2101668704","https://openalex.org/W2101982546","https://openalex.org/W2102552397","https://openalex.org/W2103065244","https://openalex.org/W2104258246","https://openalex.org/W2104323543","https://openalex.org/W2105425033","https://openalex.org/W2105662115","https://openalex.org/W2107661284","https://openalex.org/W2108140227","https://openalex.org/W2108192985","https://openalex.org/W2108702111","https://openalex.org/W2110812051","https://openalex.org/W2111371266","https://openalex.org/W2112552231","https://openalex.org/W2113184926","https://openalex.org/W2113596742","https://openalex.org/W2117539329","https://openalex.org/W2122261044","https://openalex.org/W2125826913","https://openalex.org/W2125862902","https://openalex.org/W2125951881","https://openalex.org/W2126021594","https://openalex.org/W2126265064","https://openalex.org/W2133832496","https://openalex.org/W2135439806","https://openalex.org/W2135960771","https://openalex.org/W2137178544","https://openalex.org/W2143324145","https://openalex.org/W2144179208","https://openalex.org/W2144490432","https://openalex.org/W2144776559","https://openalex.org/W2144870845","https://openalex.org/W2146280915","https://openalex.org/W2152577329","https://openalex.org/W2154685498","https://openalex.org/W2154861025","https://openalex.org/W2157606645","https://openalex.org/W2160201851","https://openalex.org/W2161624379","https://openalex.org/W2163106864","https://openalex.org/W2165325650","https://openalex.org/W2168832642","https://openalex.org/W2171498721","https://openalex.org/W2171662529","https://openalex.org/W2323202113","https://openalex.org/W2326904657","https://openalex.org/W2332239235","https://openalex.org/W2335364913","https://openalex.org/W2339917869","https://openalex.org/W2340171512","https://openalex.org/W2403048016","https://openalex.org/W2412095388","https://openalex.org/W2415773916","https://openalex.org/W2436235082","https://openalex.org/W2468150319","https://openalex.org/W2486020267"],"related_works":["https://openalex.org/W7095329686","https://openalex.org/W2116895301","https://openalex.org/W2122663415","https://openalex.org/W2378643020","https://openalex.org/W2120842622","https://openalex.org/W2341656882","https://openalex.org/W4211147758","https://openalex.org/W1630939028","https://openalex.org/W2138080281","https://openalex.org/W2309444540"],"abstract_inverted_index":{"Diabetic":[0],"nephropathy":[1,108],"has":[2],"become":[3],"the":[4,34,42,68,103],"leading":[5],"cause":[6],"of":[7,36,44,60,67,80,91,105,107],"end-stage":[8],"kidney":[9,49],"disease":[10,50,53],"worldwide":[11],"and":[12,29,51,64,109],"is":[13,24,40,71],"associated":[14],"with":[15],"an":[16],"increased":[17],"cardiovascular":[18,52,110],"risk.":[19],"The":[20],"earliest":[21],"clinical":[22],"manifestation":[23],"microalbuminuria.":[25,37],"Tight":[26],"blood":[27,30,61,93],"glucose":[28],"pressure":[31,76],"control":[32,90],"reduce":[33,100],"risk":[35],"Once":[38],"microalbuminuria":[39],"present,":[41],"rate":[43,104],"progression":[45,106],"to":[46,87],"end":[47],"stage":[48],"can":[54,97],"be":[55,85],"delayed":[56],"by":[57,101],"aggressive":[58],"management":[59],"pressure,":[62],"glucose,":[63],"lipids.":[65],"Inhibition":[66],"reninangiotensin":[69],"system":[70],"important":[72],"in":[73],"reducing":[74],"intraglomerular":[75],"but":[77],"other":[78],"classes":[79],"antihypertensive":[81],"agents":[82],"may":[83],"also":[84],"needed":[86],"obtain":[88],"adequate":[89],"systemic":[92],"pressure.":[94],"Such":[95],"measures":[96],"at":[98],"least":[99],"half":[102],"disease.":[111]},"counts_by_year":[],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2016-06-24T00:00:00"}