{"id":"https://openalex.org/W2184954526","doi":null,"title":"Bone alterations during HIV infection.","display_name":"Bone alterations during HIV infection.","publication_year":2008,"publication_date":"2008-04-01","ids":{"openalex":"https://openalex.org/W2184954526","mag":"2184954526","pmid":"https://pubmed.ncbi.nlm.nih.gov/18623979"},"language":"en","primary_location":{"id":"pmid:18623979","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18623979","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The new microbiologica","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002888060","display_name":"Elisa De Crignis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Elisa De Crignis","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, University of Bologna, Bologna, Italy. elisa.decrignis@gmail.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Bologna, Bologna, Italy. elisa.decrignis@gmail.com","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009807878","display_name":"Laura Cimatti","orcid":"https://orcid.org/0000-0002-5396-9603","observed_orcids":["https://orcid.org/0000-0002-5396-9603"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Laura Cimatti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024975408","display_name":"Marco Borderi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marco Borderi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079709625","display_name":"Davide Gibellini","orcid":"https://orcid.org/0000-0003-3688-1252","observed_orcids":["https://orcid.org/0000-0003-3688-1252"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Davide Gibellini","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5013200935","display_name":"Maria Carla Re","orcid":"https://orcid.org/0000-0003-1486-9033","observed_orcids":["https://orcid.org/0000-0003-1486-9033"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maria Carla Re","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.3306,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.79632347,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"31","issue":"2","first_page":"155","last_page":"64"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11655","display_name":"HIV-related health complications and treatments","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11655","display_name":"HIV-related health complications and treatments","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-infection","display_name":"HIV infection","score":0.8309999704360962},{"id":"https://openalex.org/keywords/hiv-1","display_name":"HIV-1","score":0.800000011920929},{"id":"https://openalex.org/keywords/osteopenia","display_name":"osteopenia","score":0.7549999952316284},{"id":"https://openalex.org/keywords/osteoporosis","display_name":"osteoporosis","score":1.0},{"id":"https://openalex.org/keywords/bone-loss","display_name":"bone loss","score":0.9980000257492065},{"id":"https://openalex.org/keywords/bone-metabolism","display_name":"bone metabolism","score":0.7570000290870667},{"id":"https://openalex.org/keywords/osteoblasts","display_name":"osteoblasts","score":0.9850000143051147},{"id":"https://openalex.org/keywords/osteoclasts","display_name":"osteoclasts","score":1.0},{"id":"https://openalex.org/keywords/bone-remodeling","display_name":"bone remodeling","score":0.5270000100135803}],"concepts":[{"id":"https://openalex.org/C2777083390","wikidata":"https://www.wikidata.org/wiki/Q1367706","display_name":"Osteopenia","level":4,"score":0.9518179893493652},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.8420857191085815},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.617465078830719},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.5958495140075684},{"id":"https://openalex.org/C2776169692","wikidata":"https://www.wikidata.org/wiki/Q4941552","display_name":"Bone disease","level":3,"score":0.5187047123908997},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3966452479362488},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3661597967147827},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.286705881357193},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22000417113304138},{"id":"https://openalex.org/C2776886416","wikidata":"https://www.wikidata.org/wiki/Q4941567","display_name":"Bone mineral","level":3,"score":0.14279791712760925}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001851","descriptor_name":"Bone Diseases, Metabolic","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D001851","descriptor_name":"Bone Diseases, Metabolic","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:18623979","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18623979","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The new microbiologica","raw_type":"Journal Article"},{"id":"pmh:oai:cris.unibo.it:11585/72145","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11585/72145","pdf_url":null,"source":{"id":"https://openalex.org/S4306402579","display_name":"Archivio istituzionale della ricerca (Alma Mater Studiorum Universit\u00e0 di Bologna)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210117483","host_organization_name":"Istituto di Ematologia di Bologna","host_organization_lineage":["https://openalex.org/I4210117483"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":92,"referenced_works":["https://openalex.org/W179196196","https://openalex.org/W1552720435","https://openalex.org/W1571166414","https://openalex.org/W1968442008","https://openalex.org/W1968552040","https://openalex.org/W1970359693","https://openalex.org/W1970782797","https://openalex.org/W1974373411","https://openalex.org/W1977724339","https://openalex.org/W1979842667","https://openalex.org/W1980106277","https://openalex.org/W1982031722","https://openalex.org/W1982869164","https://openalex.org/W1985610579","https://openalex.org/W1987538246","https://openalex.org/W1989353060","https://openalex.org/W1990006539","https://openalex.org/W1990746088","https://openalex.org/W1991351220","https://openalex.org/W1998589232","https://openalex.org/W1998661299","https://openalex.org/W1999635905","https://openalex.org/W2001162228","https://openalex.org/W2002699743","https://openalex.org/W2005321051","https://openalex.org/W2005985836","https://openalex.org/W2008786345","https://openalex.org/W2010328781","https://openalex.org/W2012250728","https://openalex.org/W2015862317","https://openalex.org/W2020702846","https://openalex.org/W2021255828","https://openalex.org/W2021871992","https://openalex.org/W2024932182","https://openalex.org/W2025162681","https://openalex.org/W2025312536","https://openalex.org/W2025683142","https://openalex.org/W2025740330","https://openalex.org/W2027372478","https://openalex.org/W2035339370","https://openalex.org/W2035527589","https://openalex.org/W2039415019","https://openalex.org/W2044787542","https://openalex.org/W2046675807","https://openalex.org/W2047167564","https://openalex.org/W2047413385","https://openalex.org/W2047461036","https://openalex.org/W2048497884","https://openalex.org/W2056881663","https://openalex.org/W2060193329","https://openalex.org/W2068100065","https://openalex.org/W2075416173","https://openalex.org/W2078819982","https://openalex.org/W2082407676","https://openalex.org/W2086774058","https://openalex.org/W2086811903","https://openalex.org/W2089789923","https://openalex.org/W2092751180","https://openalex.org/W2093252878","https://openalex.org/W2093923184","https://openalex.org/W2095607806","https://openalex.org/W2095997339","https://openalex.org/W2101762073","https://openalex.org/W2102991809","https://openalex.org/W2108063837","https://openalex.org/W2114344041","https://openalex.org/W2114506338","https://openalex.org/W2123893994","https://openalex.org/W2125243069","https://openalex.org/W2128513451","https://openalex.org/W2131579149","https://openalex.org/W2131862834","https://openalex.org/W2131978213","https://openalex.org/W2133911598","https://openalex.org/W2140317538","https://openalex.org/W2140806663","https://openalex.org/W2141528524","https://openalex.org/W2143434254","https://openalex.org/W2145334011","https://openalex.org/W2149384715","https://openalex.org/W2150539152","https://openalex.org/W2153774266","https://openalex.org/W2155081622","https://openalex.org/W2156424907","https://openalex.org/W2165446754","https://openalex.org/W2165600338","https://openalex.org/W2172159264","https://openalex.org/W2172226708","https://openalex.org/W2173151250","https://openalex.org/W2328671216","https://openalex.org/W2334961531","https://openalex.org/W2992074784"],"related_works":["https://openalex.org/W2085613347","https://openalex.org/W2049477943","https://openalex.org/W1984820507","https://openalex.org/W2789944441","https://openalex.org/W2328328362","https://openalex.org/W2044074653","https://openalex.org/W2056995969","https://openalex.org/W2091169946","https://openalex.org/W2010171897","https://openalex.org/W2027372478"],"abstract_inverted_index":{"Osteopenia":[0],"and":[1,8,14,27,67],"osteoporosis":[2],"are":[3,24],"common":[4],"in":[5,12],"HIV-1-infected":[6],"individuals":[7],"represent":[9],"a":[10],"challenge":[11],"clinical":[13],"therapeutic":[15],"management.":[16],"Since":[17],"the":[18,61,70],"mechanisms":[19,56],"underlying":[20],"this":[21,49],"degenerative":[22],"process":[23],"largely":[25],"unsettled":[26],"it":[28],"has":[29],"not":[30],"yet":[31],"been":[32],"determined":[33],"whether":[34],"bone":[35,63],"dysfunction":[36],"is":[37],"linked":[38],"to":[39],"HIV-1-mediated":[40],"direct":[41],"and/or":[42],"indirect":[43],"effects":[44],"on":[45],"osteoblasts/osteoclasts":[46],"cross-talk":[47],"regulation,":[48],"brief":[50],"review":[51],"analyzes":[52],"an":[53],"array":[54],"of":[55,72],"that":[57],"could":[58],"account":[59],"for":[60],"dramatic":[62],"derangement":[64],"(bone":[65],"loss":[66],"osteopenia/osteoporosis)":[68],"during":[69],"course":[71],"HIV-1":[73],"infection.":[74]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}