{"id":"https://openalex.org/W2184932682","doi":null,"title":"Comparative study on effect of natural and artificial superdisintegrants in the formulation of fast dissolving aspirin tablet.","display_name":"Comparative study on effect of natural and artificial superdisintegrants in the formulation of fast dissolving aspirin tablet.","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2184932682","mag":"2184932682"},"language":"en","primary_location":{"id":"mag:2184932682","doi":null,"is_oa":false,"landing_page_url":"https://www.cabdirect.org/abstracts/20103270967.html","pdf_url":null,"source":{"id":"https://openalex.org/S2765036248","display_name":"Journal of Pharmacy Research","issn_l":"0974-6943","issn":["0974-6943"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Pharmacy Research","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087603748","display_name":"Nikku Yadav","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nikku Yadav","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013087712","display_name":"Prashant Pingale","orcid":"https://orcid.org/0000-0002-5060-3251","observed_orcids":["https://orcid.org/0000-0002-5060-3251"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Prashant Pingale","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5060-3251","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5012459054","display_name":"Sagar R. Tatane","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sagar R. Tatane","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4425,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.55129012,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"3","issue":"7","first_page":"1594","last_page":"1597"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10615","display_name":"Granular flow and fluidized beds","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2206","display_name":"Computational Mechanics"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aspirin","display_name":"aspirin","score":0.777999997138977},{"id":"https://openalex.org/keywords/fast-dissolving-tablets","display_name":"fast dissolving tablets","score":0.9950000047683716},{"id":"https://openalex.org/keywords/superdisintegrants","display_name":"superdisintegrants","score":0.9950000047683716},{"id":"https://openalex.org/keywords/natural-superdisintegrants","display_name":"natural superdisintegrants","score":0.8939999938011169},{"id":"https://openalex.org/keywords/ac-di-sol","display_name":"Ac-Di-Sol","score":0.734000027179718},{"id":"https://openalex.org/keywords/crospovidone","display_name":"crospovidone","score":0.9470000267028809},{"id":"https://openalex.org/keywords/sodium-starch-glycolate","display_name":"sodium starch glycolate","score":0.9909999966621399},{"id":"https://openalex.org/keywords/swelling-index","display_name":"swelling index","score":0.8019999861717224},{"id":"https://openalex.org/keywords/disintegration-time","display_name":"disintegration time","score":0.8529999852180481},{"id":"https://openalex.org/keywords/tablet-formulation","display_name":"tablet formulation","score":0.5009999871253967},{"id":"https://openalex.org/keywords/direct-compression","display_name":"direct compression","score":0.777999997138977}],"concepts":[{"id":"https://openalex.org/C2780658084","wikidata":"https://www.wikidata.org/wiki/Q311228","display_name":"Plantago ovata","level":2,"score":0.9056745171546936},{"id":"https://openalex.org/C191168616","wikidata":"https://www.wikidata.org/wiki/Q5503337","display_name":"Friability","level":4,"score":0.797683835029602},{"id":"https://openalex.org/C2778540859","wikidata":"https://www.wikidata.org/wiki/Q152234","display_name":"Swelling","level":2,"score":0.7342038154602051},{"id":"https://openalex.org/C75296557","wikidata":"https://www.wikidata.org/wiki/Q14524280","display_name":"Husk","level":2,"score":0.6515215635299683},{"id":"https://openalex.org/C2777091354","wikidata":"https://www.wikidata.org/wiki/Q5188058","display_name":"Croscarmellose sodium","level":4,"score":0.5624682307243347},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4362199902534485},{"id":"https://openalex.org/C88380143","wikidata":"https://www.wikidata.org/wiki/Q416674","display_name":"Dissolution","level":2,"score":0.43469002842903137},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40599510073661804},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.3969673216342926},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.34028518199920654},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.30209726095199585},{"id":"https://openalex.org/C181389837","wikidata":"https://www.wikidata.org/wiki/Q461809","display_name":"Bioavailability","level":2,"score":0.28560444712638855},{"id":"https://openalex.org/C77281830","wikidata":"https://www.wikidata.org/wiki/Q718608","display_name":"Dosage form","level":2,"score":0.20889541506767273},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.20694318413734436},{"id":"https://openalex.org/C2778572730","wikidata":"https://www.wikidata.org/wiki/Q416713","display_name":"Magnesium stearate","level":3,"score":0.17040467262268066},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.11137250065803528},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08525398373603821},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.08046761155128479},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.07230252027511597},{"id":"https://openalex.org/C201253974","wikidata":"https://www.wikidata.org/wiki/Q1330121","display_name":"First pass effect","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2184932682","doi":null,"is_oa":false,"landing_page_url":"https://www.cabdirect.org/abstracts/20103270967.html","pdf_url":null,"source":{"id":"https://openalex.org/S2765036248","display_name":"Journal of Pharmacy Research","issn_l":"0974-6943","issn":["0974-6943"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Pharmacy Research","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1517783166","https://openalex.org/W1566408227","https://openalex.org/W2072152949","https://openalex.org/W2098988099","https://openalex.org/W2106563238","https://openalex.org/W2146504168","https://openalex.org/W2159269801","https://openalex.org/W2160458846","https://openalex.org/W2606197978","https://openalex.org/W4248344362"],"related_works":["https://openalex.org/W1509290659","https://openalex.org/W1505143142","https://openalex.org/W2232345744","https://openalex.org/W2219252410","https://openalex.org/W4414591647","https://openalex.org/W4413912393","https://openalex.org/W7078965563","https://openalex.org/W2726485798","https://openalex.org/W2895794206","https://openalex.org/W7165840023"],"abstract_inverted_index":{"Aspirin":[0,52],"is":[1,114],"a":[2,34],"salicylate":[3],"drug":[4],"and":[5,14,22,37,78,100,139],"used":[6,132],"as":[7,16,23],"an":[8,17,24,86],"analgesic":[9],"to":[10,19,88],"relieve":[11],"minor":[12],"aches":[13],"pains,":[15],"antipyretic":[18],"reduce":[20],"fever,":[21],"anti-inflammatory":[25],"medication.":[26],"In":[27],"the":[28,31,43,90,108,129,144],"present":[29],"study,":[30],"effects":[32],"of":[33,45,51,93,120,146],"natural":[35,117],"superdisintegrants":[36,39,118],"synthetic":[38,133],"were":[40,53,61],"compared":[41],"in":[42,143],"formulations":[44,145],"fast":[46],"dissolving":[47],"tablets":[48,60],"(FDT).":[49],"FDTs":[50],"prepared":[54],"by":[55],"direct":[56],"compression":[57],"method.":[58],"These":[59],"evaluated":[62],"for":[63],"weight":[64],"variation,":[65],"hardness,":[66],"thickness,":[67],"disintegration":[68],"time,":[69,71,74],"dispersion":[70],"friability,":[72],"wetting":[73],"water":[75],"absorption":[76],"ration":[77],"dissolution.":[79],"Swelling":[80],"index":[81],"was":[82],"also":[83],"observed":[84],"with":[85,97],"objective":[87],"compare":[89],"swelling":[91,110],"property":[92,127],"Plantag":[94],"ovata":[95,105,122],"husk":[96,106],"Ac-di-sol,":[98],"Crospovidone":[99],"sodium":[101],"Starch":[102],"glycolate.":[103],"Plantago":[104,121],"showed":[107,124],"highest":[109],"index.":[111],"Hence,":[112],"it":[113],"concluded":[115],"that":[116],"(husk":[119],")":[123],"better":[125],"disintegrating":[126],"than":[128],"most":[130],"widely":[131],"super":[134],"disintegrants":[135],"like":[136],"Crospovidone,":[137],"Ac-di-sol":[138],"Sodium":[140],"starch":[141],"glycolate":[142],"FDTs.":[147]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}