{"id":"https://openalex.org/W2183294434","doi":null,"title":"A candidate gene analysis of response to citalopram and escitalopram treatment in patients with Major Depressive Disorder and Generalized Anxiety Disorder","display_name":"A candidate gene analysis of response to citalopram and escitalopram treatment in patients with Major Depressive Disorder and Generalized Anxiety Disorder","publication_year":2010,"publication_date":"2010-08-31","ids":{"openalex":"https://openalex.org/W2183294434","mag":"2183294434"},"language":"en","primary_location":{"id":"pmh:oai:queensu.scholaris.ca:1974/6003","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1974/6003","pdf_url":null,"source":{"id":"https://openalex.org/S4306402568","display_name":"QSpace (Queen's University Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I204722609","host_organization_name":"Queen's University","host_organization_lineage":["https://openalex.org/I204722609"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113702447","display_name":"Laura Gedge","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Laura Gedge","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5113702447"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.8564000129699707,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.8564000129699707,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.10740000009536743,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.01889999955892563,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/candidate-gene-studies","display_name":"candidate gene association","score":0.8140000104904175},{"id":"https://openalex.org/keywords/citalopram","display_name":"citalopram","score":0.9150000214576721},{"id":"https://openalex.org/keywords/escitalopram","display_name":"escitalopram","score":1.0},{"id":"https://openalex.org/keywords/major-depressive-disorder","display_name":"major depressive disorder","score":0.7929999828338623},{"id":"https://openalex.org/keywords/generalized-anxiety-disorder","display_name":"generalized anxiety disorder","score":1.0},{"id":"https://openalex.org/keywords/antidepressant-response","display_name":"antidepressant response","score":0.7850000262260437},{"id":"https://openalex.org/keywords/genetic-polymorphism","display_name":"genetic polymorphism","score":0.5989999771118164},{"id":"https://openalex.org/keywords/selective-serotonin-reuptake-inhibitors","display_name":"selective serotonin reuptake inhibitors","score":0.8259999752044678}],"concepts":[{"id":"https://openalex.org/C2779583969","wikidata":"https://www.wikidata.org/wiki/Q423757","display_name":"Escitalopram","level":4,"score":0.9571973085403442},{"id":"https://openalex.org/C2777490545","wikidata":"https://www.wikidata.org/wiki/Q409672","display_name":"Citalopram","level":4,"score":0.8339450359344482},{"id":"https://openalex.org/C2780051608","wikidata":"https://www.wikidata.org/wiki/Q42844","display_name":"Major depressive disorder","level":3,"score":0.7875499129295349},{"id":"https://openalex.org/C2779911313","wikidata":"https://www.wikidata.org/wiki/Q845224","display_name":"Generalized anxiety disorder","level":3,"score":0.6639530658721924},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5562049150466919},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.5496455430984497},{"id":"https://openalex.org/C2776317618","wikidata":"https://www.wikidata.org/wiki/Q544006","display_name":"Anxiety disorder","level":3,"score":0.520172119140625},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.5064209699630737},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.44970768690109253},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.4405432939529419},{"id":"https://openalex.org/C2779177272","wikidata":"https://www.wikidata.org/wiki/Q76560","display_name":"Antidepressant","level":3,"score":0.3915274739265442},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.130791574716568},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:queensu.scholaris.ca:1974/6003","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1974/6003","pdf_url":null,"source":{"id":"https://openalex.org/S4306402568","display_name":"QSpace (Queen's University Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I204722609","host_organization_name":"Queen's University","host_organization_lineage":["https://openalex.org/I204722609"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"thesis"},{"id":"mag:2183294434","doi":null,"is_oa":false,"landing_page_url":"https://qspace.library.queensu.ca/bitstream/1974/6003/1/Gedge_Laura_August%202010_M.Sc%20Neuroscience.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":195,"referenced_works":["https://openalex.org/W70712876","https://openalex.org/W167911861","https://openalex.org/W191982317","https://openalex.org/W192588373","https://openalex.org/W202829357","https://openalex.org/W341795939","https://openalex.org/W1500276767","https://openalex.org/W1519202038","https://openalex.org/W1520014704","https://openalex.org/W1551014807","https://openalex.org/W1596415735","https://openalex.org/W1608407352","https://openalex.org/W1709410479","https://openalex.org/W1748703215","https://openalex.org/W1769470409","https://openalex.org/W1882921275","https://openalex.org/W1894736765","https://openalex.org/W1928975456","https://openalex.org/W1963856882","https://openalex.org/W1969143567","https://openalex.org/W1970188324","https://openalex.org/W1972563980","https://openalex.org/W1972663341","https://openalex.org/W1973713042","https://openalex.org/W1973994559","https://openalex.org/W1974253960","https://openalex.org/W1974383964","https://openalex.org/W1976122155","https://openalex.org/W1977160269","https://openalex.org/W1980135097","https://openalex.org/W1980325750","https://openalex.org/W1981413819","https://openalex.org/W1982765225","https://openalex.org/W1985399534","https://openalex.org/W1985692899","https://openalex.org/W1989218867","https://openalex.org/W1993034676","https://openalex.org/W1995556701","https://openalex.org/W1996395058","https://openalex.org/W1999913805","https://openalex.org/W2001044475","https://openalex.org/W2005534453","https://openalex.org/W2010269783","https://openalex.org/W2011284219","https://openalex.org/W2011878867","https://openalex.org/W2012102163","https://openalex.org/W2013323759","https://openalex.org/W2013384289","https://openalex.org/W2016364360","https://openalex.org/W2016467294","https://openalex.org/W2016512181","https://openalex.org/W2016619393","https://openalex.org/W2016725019","https://openalex.org/W2019316537","https://openalex.org/W2019988283","https://openalex.org/W2020198222","https://openalex.org/W2023574802","https://openalex.org/W2023653401","https://openalex.org/W2024256650","https://openalex.org/W2026820556","https://openalex.org/W2027702949","https://openalex.org/W2030026084","https://openalex.org/W2030062993","https://openalex.org/W2033309297","https://openalex.org/W2035266273","https://openalex.org/W2035663126","https://openalex.org/W2036511379","https://openalex.org/W2036744872","https://openalex.org/W2037329949","https://openalex.org/W2037481801","https://openalex.org/W2038716310","https://openalex.org/W2039071791","https://openalex.org/W2040223618","https://openalex.org/W2040263710","https://openalex.org/W2043175890","https://openalex.org/W2043443271","https://openalex.org/W2044710410","https://openalex.org/W2045020364","https://openalex.org/W2045728711","https://openalex.org/W2045973153","https://openalex.org/W2046809238","https://openalex.org/W2047170290","https://openalex.org/W2047200908","https://openalex.org/W2049098623","https://openalex.org/W2049527568","https://openalex.org/W2050550316","https://openalex.org/W2051531767","https://openalex.org/W2053343116","https://openalex.org/W2055747883","https://openalex.org/W2056674018","https://openalex.org/W2058634418","https://openalex.org/W2058702631","https://openalex.org/W2059568608","https://openalex.org/W2060056442","https://openalex.org/W2060345189","https://openalex.org/W2061730652","https://openalex.org/W2062171323","https://openalex.org/W2062634104","https://openalex.org/W2062815987","https://openalex.org/W2063237368","https://openalex.org/W2063993627","https://openalex.org/W2067343408","https://openalex.org/W2070422137","https://openalex.org/W2070861572","https://openalex.org/W2072219714","https://openalex.org/W2072698152","https://openalex.org/W2072842751","https://openalex.org/W2073168334","https://openalex.org/W2073432994","https://openalex.org/W2074356620","https://openalex.org/W2075362165","https://openalex.org/W2076053093","https://openalex.org/W2076112136","https://openalex.org/W2079874942","https://openalex.org/W2080100695","https://openalex.org/W2081458788","https://openalex.org/W2082363592","https://openalex.org/W2082981647","https://openalex.org/W2084090342","https://openalex.org/W2084340196","https://openalex.org/W2084399551","https://openalex.org/W2084543750","https://openalex.org/W2084726883","https://openalex.org/W2084965184","https://openalex.org/W2086414140","https://openalex.org/W2087209021","https://openalex.org/W2087519774","https://openalex.org/W2088226858","https://openalex.org/W2088504456","https://openalex.org/W2089694151","https://openalex.org/W2090561131","https://openalex.org/W2091967472","https://openalex.org/W2093724967","https://openalex.org/W2093837465","https://openalex.org/W2094106822","https://openalex.org/W2096991502","https://openalex.org/W2098760758","https://openalex.org/W2100040984","https://openalex.org/W2102308750","https://openalex.org/W2106095564","https://openalex.org/W2106885532","https://openalex.org/W2108143899","https://openalex.org/W2109917479","https://openalex.org/W2110219512","https://openalex.org/W2113354422","https://openalex.org/W2114634718","https://openalex.org/W2116152046","https://openalex.org/W2116962246","https://openalex.org/W2117053539","https://openalex.org/W2118826874","https://openalex.org/W2120599193","https://openalex.org/W2122175586","https://openalex.org/W2122681119","https://openalex.org/W2123738251","https://openalex.org/W2127017530","https://openalex.org/W2129633806","https://openalex.org/W2130639132","https://openalex.org/W2134334380","https://openalex.org/W2134880633","https://openalex.org/W2136749432","https://openalex.org/W2137296158","https://openalex.org/W2137416893","https://openalex.org/W2137744200","https://openalex.org/W2138419072","https://openalex.org/W2139502395","https://openalex.org/W2144538553","https://openalex.org/W2145151017","https://openalex.org/W2145557211","https://openalex.org/W2146747402","https://openalex.org/W2147125053","https://openalex.org/W2149946283","https://openalex.org/W2153504955","https://openalex.org/W2156587055","https://openalex.org/W2156743186","https://openalex.org/W2157710709","https://openalex.org/W2158455820","https://openalex.org/W2158533153","https://openalex.org/W2161085199","https://openalex.org/W2163918328","https://openalex.org/W2165616253","https://openalex.org/W2167977201","https://openalex.org/W2169100323","https://openalex.org/W2169192753","https://openalex.org/W2202478075","https://openalex.org/W2323212802","https://openalex.org/W2324102686","https://openalex.org/W2397426560","https://openalex.org/W2410218281","https://openalex.org/W2421183231","https://openalex.org/W2802022988","https://openalex.org/W2885386535","https://openalex.org/W3022677499","https://openalex.org/W4253268125","https://openalex.org/W4298701794","https://openalex.org/W4399865119"],"related_works":["https://openalex.org/W1970934314","https://openalex.org/W7098167673","https://openalex.org/W4235235734","https://openalex.org/W2119293054","https://openalex.org/W7019346182","https://openalex.org/W3144795016","https://openalex.org/W2971202664","https://openalex.org/W2043432295","https://openalex.org/W4398167008","https://openalex.org/W4405637640"],"abstract_inverted_index":{"Thesis":[0],"(Master,":[1],"Neuroscience":[2],"Studies)":[3],"--":[4],"Queen's":[5],"University,":[6],"2010-08-31":[7],"12:26:21.402":[8]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
