{"id":"https://openalex.org/W2183269144","doi":null,"title":"A randomized, open-label, crossover trial evaluating sexual self- confidence and other therapeutic clinical results following the once-a-day administration of tadalafil vs. on-demand tadalafil or sildenafil in Mexican men with erectile dysfunction","display_name":"A randomized, open-label, crossover trial evaluating sexual self- confidence and other therapeutic clinical results following the once-a-day administration of tadalafil vs. on-demand tadalafil or sildenafil in Mexican men with erectile dysfunction","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2183269144","mag":"2183269144"},"language":"en","primary_location":{"id":"mag:2183269144","doi":null,"is_oa":false,"landing_page_url":"http://www.revistamexicanadeurologia.com/Revistas/2014/ingles/May-June/06%20AO%20ESTUDIO%20ALEATORIZADO.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006161861","display_name":"Eusebio Rubio Aurioles","orcid":"https://orcid.org/0000-0002-8307-9353","observed_orcids":["https://orcid.org/0000-0002-8307-9353"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eus\u00e9bio Rubio-Aurioles","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8307-9353","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022282469","display_name":"Rafael Mart\u00ednez Montelongo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Mart\u00ednez-Montelongo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078171621","display_name":"F. Barrios","orcid":"https://orcid.org/0000-0001-6956-7230","observed_orcids":["https://orcid.org/0000-0001-6956-7230"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F. Barrios","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6956-7230","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069328349","display_name":"Sebastian Sorsaburu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sebastian Sorsaburu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5074598743","display_name":"Luis Antonio Reyes-Vallejo","orcid":"https://orcid.org/0000-0002-5144-8089","observed_orcids":["https://orcid.org/0000-0002-5144-8089"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luis Antonio Reyes-Vallejo","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5144-8089","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10459","display_name":"Sexual function and dysfunction studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10459","display_name":"Sexual function and dysfunction studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11815","display_name":"Urological Disorders and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12335","display_name":"Sexuality, Behavior, and Technology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/erectile-dysfunction","display_name":"erectile dysfunction","score":1.0},{"id":"https://openalex.org/keywords/tadalafil","display_name":"tadalafil","score":0.9279999732971191},{"id":"https://openalex.org/keywords/sildenafil","display_name":"sildenafil","score":0.925000011920929},{"id":"https://openalex.org/keywords/phosphodiesterase-5-inhibitors","display_name":"phosphodiesterase-5 inhibitors","score":0.800000011920929},{"id":"https://openalex.org/keywords/sexual-self-confidence","display_name":"sexual confidence","score":0.996999979019165},{"id":"https://openalex.org/keywords/psychosocial-outcomes","display_name":"psychosocial outcomes","score":0.7929999828338623},{"id":"https://openalex.org/keywords/spontaneity","display_name":"spontaneity","score":0.8640000224113464},{"id":"https://openalex.org/keywords/mexican-men","display_name":"Mexican men","score":0.8450000286102295}],"concepts":[{"id":"https://openalex.org/C2780816001","wikidata":"https://www.wikidata.org/wiki/Q424156","display_name":"Tadalafil","level":3,"score":0.9892368316650391},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7973471879959106},{"id":"https://openalex.org/C2776768464","wikidata":"https://www.wikidata.org/wiki/Q191521","display_name":"Sildenafil","level":2,"score":0.778390645980835},{"id":"https://openalex.org/C2779929075","wikidata":"https://www.wikidata.org/wiki/Q184674","display_name":"Erectile dysfunction","level":2,"score":0.6783918738365173},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.5599537491798401},{"id":"https://openalex.org/C74534348","wikidata":"https://www.wikidata.org/wiki/Q410798","display_name":"cGMP-specific phosphodiesterase type 5","level":3,"score":0.5576954483985901},{"id":"https://openalex.org/C87813604","wikidata":"https://www.wikidata.org/wiki/Q1242899","display_name":"Crossover study","level":4,"score":0.5250779986381531},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.4965105652809143},{"id":"https://openalex.org/C2778822586","wikidata":"https://www.wikidata.org/wiki/Q424161","display_name":"Vardenafil","level":4,"score":0.45372653007507324},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.45186617970466614},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3649340271949768},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.3386666178703308},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2183269144","doi":null,"is_oa":false,"landing_page_url":"http://www.revistamexicanadeurologia.com/Revistas/2014/ingles/May-June/06%20AO%20ESTUDIO%20ALEATORIZADO.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W82521790","https://openalex.org/W992134367","https://openalex.org/W1848581113","https://openalex.org/W1948606468","https://openalex.org/W1964185316","https://openalex.org/W1964561331","https://openalex.org/W1971555927","https://openalex.org/W1971833377","https://openalex.org/W1977736486","https://openalex.org/W1999059326","https://openalex.org/W2015558402","https://openalex.org/W2026664968","https://openalex.org/W2038448732","https://openalex.org/W2045900114","https://openalex.org/W2048510599","https://openalex.org/W2058983614","https://openalex.org/W2086240335","https://openalex.org/W2088106865","https://openalex.org/W2090549090","https://openalex.org/W2117617888","https://openalex.org/W2125733039","https://openalex.org/W2134025139","https://openalex.org/W2144115195","https://openalex.org/W2155346477","https://openalex.org/W2167711393"],"related_works":["https://openalex.org/W2155346477","https://openalex.org/W2091726420","https://openalex.org/W2411728535","https://openalex.org/W2047767981","https://openalex.org/W2157901881","https://openalex.org/W2040950733","https://openalex.org/W1968285708","https://openalex.org/W1948606468","https://openalex.org/W2077439805","https://openalex.org/W2041177840"],"abstract_inverted_index":{"Background:":[0],"Erectile":[1],"dysfunction":[2,30,72],"is":[3],"an":[4,62],"entity":[5],"that":[6,31,73],"has":[7],"a":[8,23,35,50,55,212],"high":[9],"prevalence":[10],"worldwide.":[11],"Aims:":[12],"To":[13],"compare":[14],"the":[15,20,86,91,100,103,109,118,172,176],"psychosocial":[16],"clinical":[17],"results":[18],"of":[19,22,25,54,57,67,117,137,178],"analysis":[21,53],"subgroup":[24,56],"Mexican":[26,58,95,207],"men":[27,59,68,208],"with":[28,70,77,122,130,157,186,193,209,229],"erectile":[29,71],"received":[32],"tadalafil":[33,38,123,131,158,161,187,194,230,233],"once":[34],"day":[36],"(OaD),":[37],"on":[39],"demand":[40],"(PRN),":[41],"or":[42],"sildenafil":[43,126,134,190,197,238],"PRN.":[44,83,198,239],"Methods:":[45],"The":[46,97,169],"present":[47],"study":[48,66],"was":[49,105,155],"post":[51],"hoc":[52],"taken":[60],"from":[61,99],"open,":[63],"randomized,":[64],"cross-sectional":[65],"presenting":[69],"were":[74,94,183,204],"previously":[75],"treated":[76,228],"phosphodiesterase":[78],"type":[79],"5":[80],"(PDE5)":[81],"inhibitors":[82],"Results:":[84],"Of":[85],"378":[87],"patients":[88],"included":[89],"in":[90,108,171,215],"study,":[92],"84":[93],"subjects.":[96],"change":[98],"baseline":[101],"to":[102,224,237],"endpoint":[104],"significantly":[106,184],"greater":[107],"Psychological":[110],"and":[111,128,144,180,192,219,232],"Interpersonal":[112],"Relationship":[113],"Scales":[114],"(PAIRS)":[115],"score":[116],"Sexual":[119],"Self-Confidence":[120],"domain":[121],"OaD":[124,159,188,231],"vs.":[125,133,160,189,196],"PRN":[127,132,135,162,191,195],"also":[129],"(differences":[136],"0.25":[138],"\u00b1":[139,146,164],"0.08":[140,165],"[0.10,":[141],"0.40];":[142],"p=0.001":[143],"0.28":[145],"0.08;":[147],"[0.13,":[148],"0.43];":[149],"p<0.001,":[150],"respectively).":[151],"No":[152],"significant":[153],"difference":[154],"observed":[156],"(-0.03":[163],"[-0.19,":[166],"0.12];":[167],"p=0.652).":[168],"changes":[170],"PAIRS":[173],"scores":[174],"for":[175],"domains":[177],"Spontaneity":[179],"Time":[181],"Concerns":[182],"higher":[185],"Three":[199],"serious":[200],"adverse":[201],"events":[202],"(SAEs)":[203],"reported.":[205],"Conclusions:":[206],"ED":[210],"showed":[211],"superior":[213],"improvement":[214],"sexual":[216,225],"self-confidence,":[217],"spontaneity,":[218],"reduced":[220],"time":[221],"concerns":[222],"related":[223],"activity":[226],"when":[227],"PRN,":[234],"as":[235],"opposed":[236]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2016-06-24T00:00:00"}