{"id":"https://openalex.org/W2183243867","doi":null,"title":"Hormone-based therapies in MS.","display_name":"Hormone-based therapies in MS.","publication_year":2003,"publication_date":"2003-06-01","ids":{"openalex":"https://openalex.org/W2183243867","mag":"2183243867","pmid":"https://pubmed.ncbi.nlm.nih.gov/14561384"},"language":"en","primary_location":{"id":"pmid:14561384","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14561384","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International MS journal","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028071943","display_name":"Rhonda R. Voskuhl","orcid":"https://orcid.org/0000-0003-2620-4346","observed_orcids":["https://orcid.org/0000-0003-2620-4346"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"R R Voskuhl","raw_affiliation_strings":["UCLA Multiple Sclerosis Program, Department of Neurology, University of California-Los Angeles, 710 Westwood Plaza, A145, Los Angeles, CA 90095, USA. rvoskuhl@ucla.edu","UCLA Multiple Sclerosis Program, Department of Neurology, University of California-Los Angeles, 710 Westwood Plaza, A145, Los Angeles, CA 90095, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCLA Multiple Sclerosis Program, Department of Neurology, University of California-Los Angeles, 710 Westwood Plaza, A145, Los Angeles, CA 90095, USA. rvoskuhl@ucla.edu","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"UCLA Multiple Sclerosis Program, Department of Neurology, University of California-Los Angeles, 710 Westwood Plaza, A145, Los Angeles, CA 90095, USA","institution_ids":["https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5028071943"],"corresponding_institution_ids":["https://openalex.org/I161318765"],"apc_list":null,"apc_paid":null,"fwci":1.2599,"has_fulltext":false,"cited_by_count":34,"citation_normalized_percentile":{"value":0.7727974,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"10","issue":"2","first_page":"60","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11964","display_name":"Pregnancy and Medication Impact","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiple-sclerosis","display_name":"multiple sclerosis","score":1.0},{"id":"https://openalex.org/keywords/estrogen","display_name":"estrogen","score":0.8489999771118164},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.7960000038146973},{"id":"https://openalex.org/keywords/postpartum-relapse","display_name":"postpartum relapse","score":0.8270000219345093},{"id":"https://openalex.org/keywords/relapse-rate","display_name":"relapse rate","score":0.7089999914169312},{"id":"https://openalex.org/keywords/immune-response","display_name":"immune response","score":0.6269999742507935},{"id":"https://openalex.org/keywords/hormonal-changes","display_name":"hormonal changes","score":0.35100001096725464}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8904410600662231},{"id":"https://openalex.org/C2780640218","wikidata":"https://www.wikidata.org/wiki/Q8277","display_name":"Multiple sclerosis","level":2,"score":0.8095768094062805},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.7849047183990479},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.6188921928405762},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5250579714775085},{"id":"https://openalex.org/C2780275930","wikidata":"https://www.wikidata.org/wiki/Q1628266","display_name":"Hormone therapy","level":4,"score":0.4318808913230896},{"id":"https://openalex.org/C3018745865","wikidata":"https://www.wikidata.org/wiki/Q749115","display_name":"Postpartum period","level":3,"score":0.413847953081131},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.40436941385269165},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.37078148126602173},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3449908494949341},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2684882879257202},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.08989357948303223},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004967","descriptor_name":"Estrogens","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D004967","descriptor_name":"Estrogens","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009103","descriptor_name":"Multiple Sclerosis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009103","descriptor_name":"Multiple Sclerosis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:14561384","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14561384","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International MS journal","raw_type":"Journal Article"},{"id":"mag:2183243867","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14561384","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":82,"referenced_works":["https://openalex.org/W184483509","https://openalex.org/W1502488470","https://openalex.org/W1540765995","https://openalex.org/W1542260479","https://openalex.org/W1543098232","https://openalex.org/W1544586439","https://openalex.org/W1564115604","https://openalex.org/W1582870359","https://openalex.org/W1593442063","https://openalex.org/W1714360375","https://openalex.org/W1897632974","https://openalex.org/W1903028880","https://openalex.org/W1931048663","https://openalex.org/W1971215056","https://openalex.org/W1974139494","https://openalex.org/W1979358011","https://openalex.org/W1982435041","https://openalex.org/W1983895762","https://openalex.org/W1984298540","https://openalex.org/W1989990363","https://openalex.org/W1992790770","https://openalex.org/W1994953189","https://openalex.org/W2008025160","https://openalex.org/W2011768190","https://openalex.org/W2017037048","https://openalex.org/W2017841541","https://openalex.org/W2019239536","https://openalex.org/W2023022532","https://openalex.org/W2025077572","https://openalex.org/W2028233455","https://openalex.org/W2030090541","https://openalex.org/W2035445993","https://openalex.org/W2035868659","https://openalex.org/W2041001602","https://openalex.org/W2041722774","https://openalex.org/W2043727652","https://openalex.org/W2047349398","https://openalex.org/W2049436228","https://openalex.org/W2053516651","https://openalex.org/W2058131310","https://openalex.org/W2058245650","https://openalex.org/W2059985338","https://openalex.org/W2060979547","https://openalex.org/W2070218857","https://openalex.org/W2070421466","https://openalex.org/W2071768705","https://openalex.org/W2072325998","https://openalex.org/W2074788705","https://openalex.org/W2078991266","https://openalex.org/W2082648762","https://openalex.org/W2084823166","https://openalex.org/W2087527641","https://openalex.org/W2092625116","https://openalex.org/W2094974233","https://openalex.org/W2103792336","https://openalex.org/W2106274323","https://openalex.org/W2107672547","https://openalex.org/W2110451811","https://openalex.org/W2111398489","https://openalex.org/W2113431672","https://openalex.org/W2113917022","https://openalex.org/W2119308919","https://openalex.org/W2128727471","https://openalex.org/W2130695898","https://openalex.org/W2132171635","https://openalex.org/W2135551891","https://openalex.org/W2137125258","https://openalex.org/W2137580566","https://openalex.org/W2141737778","https://openalex.org/W2143241373","https://openalex.org/W2144272087","https://openalex.org/W2149511379","https://openalex.org/W2157275878","https://openalex.org/W2158321701","https://openalex.org/W2171907184","https://openalex.org/W2319459971","https://openalex.org/W2327556717","https://openalex.org/W2383806028","https://openalex.org/W2416053118","https://openalex.org/W2418634795","https://openalex.org/W2465258556","https://openalex.org/W2472636316"],"related_works":["https://openalex.org/W613172373","https://openalex.org/W4242467287","https://openalex.org/W2211297114","https://openalex.org/W3174589881","https://openalex.org/W2135551891","https://openalex.org/W2086016472","https://openalex.org/W2008586010","https://openalex.org/W2140658267","https://openalex.org/W4249522670","https://openalex.org/W2167851515"],"abstract_inverted_index":{"It":[0],"is":[1,26,59],"well":[2],"established":[3],"in":[4,14,19,44],"multiple":[5],"sclerosis":[6],"(MS)":[7],"that":[8],"the":[9,20],"frequency":[10],"of":[11,53],"relapses":[12],"decreases":[13],"late":[15],"pregnancy,":[16],"but":[17],"increases":[18],"post-partum":[21],"period.":[22],"This":[23],"protective":[24,48],"effect":[25],"probably":[27],"due":[28],"to":[29],"hormonal":[30],"and":[31],"immune":[32],"response":[33],"changes":[34],"induced":[35],"by":[36],"pregnancy.":[37],"Oestrogens":[38],"may":[39],"be":[40],"responsible,":[41],"at":[42],"least":[43],"part,":[45],"for":[46,57],"this":[47],"effect.":[49],"The":[50],"potential":[51],"use":[52],"oestrogens":[54],"as":[55],"therapy":[56],"MS":[58],"discussed.":[60]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}