{"id":"https://openalex.org/W2183240393","doi":null,"title":"Antitumor and antioxidant potentials of ethanolic extract of Leonotis nepetaefolia R.Br. against Ehrlich Ascites carcinoma cell lines.","display_name":"Antitumor and antioxidant potentials of ethanolic extract of Leonotis nepetaefolia R.Br. against Ehrlich Ascites carcinoma cell lines.","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2183240393","mag":"2183240393"},"language":"en","primary_location":{"id":"mag:2183240393","doi":null,"is_oa":false,"landing_page_url":"https://www.cabdirect.org/abstracts/20113062995.html","pdf_url":null,"source":{"id":"https://openalex.org/S2765036248","display_name":"Journal of Pharmacy Research","issn_l":"0974-6943","issn":["0974-6943"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Pharmacy Research","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006501166","display_name":"Gurunagarajan Sridharan","orcid":"https://orcid.org/0000-0003-4861-6050","observed_orcids":["https://orcid.org/0000-0003-4861-6050"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Sridharan","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4861-6050","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5110459804","display_name":"Brindha Pemaiah","orcid":"https://orcid.org/0000-0002-9537-2557","observed_orcids":["https://orcid.org/0000-0002-9537-2557"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brindha Pemaiah","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1365,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.78998752,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"3","issue":"12","first_page":"2990","last_page":"2992"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12215","display_name":"Phytochemical Studies and Bioactivities","score":0.00559999980032444,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14135","display_name":"Cancer and biochemical research","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ethanolic-plant-extract","display_name":"ethanolic plant extract","score":0.9079999923706055},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.9670000076293945},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.9679999947547913},{"id":"https://openalex.org/keywords/ehrlich-ascites-carcinoma","display_name":"Ehrlich ascites carcinoma","score":0.996999979019165},{"id":"https://openalex.org/keywords/ascites","display_name":"ascites","score":0.5680000185966492},{"id":"https://openalex.org/keywords/hematological-parameters","display_name":"hematological parameters","score":0.9049999713897705},{"id":"https://openalex.org/keywords/antioxidant-enzymes","display_name":"antioxidant enzymes","score":0.9309999942779541},{"id":"https://openalex.org/keywords/survival-time","display_name":"survival time","score":0.7459999918937683},{"id":"https://openalex.org/keywords/5-fluorouracil-comparison","display_name":"5-fluorouracil comparison","score":0.8690000176429749},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.546999990940094}],"concepts":[{"id":"https://openalex.org/C2776197502","wikidata":"https://www.wikidata.org/wiki/Q25326666","display_name":"Ehrlich ascites carcinoma","level":3,"score":0.9476239681243896},{"id":"https://openalex.org/C2780496750","wikidata":"https://www.wikidata.org/wiki/Q193889","display_name":"Ascites","level":2,"score":0.785118818283081},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.7168603539466858},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.6015215516090393},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.45602673292160034},{"id":"https://openalex.org/C2909082478","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma Cell","level":3,"score":0.4116489291191101},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36780011653900146},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3465166687965393},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3355613350868225},{"id":"https://openalex.org/C3020616263","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Tumor cells","level":2,"score":0.30288076400756836},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2735912799835205},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.1609487235546112},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15741834044456482}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2183240393","doi":null,"is_oa":false,"landing_page_url":"https://www.cabdirect.org/abstracts/20113062995.html","pdf_url":null,"source":{"id":"https://openalex.org/S2765036248","display_name":"Journal of Pharmacy Research","issn_l":"0974-6943","issn":["0974-6943"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Pharmacy Research","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W116684277","https://openalex.org/W1445103006","https://openalex.org/W1566830427","https://openalex.org/W1584531376","https://openalex.org/W1866029529","https://openalex.org/W1983310681","https://openalex.org/W1984012157","https://openalex.org/W2005643366","https://openalex.org/W2010254230","https://openalex.org/W2051122173","https://openalex.org/W2110421117","https://openalex.org/W2127940604","https://openalex.org/W2268364751","https://openalex.org/W2418242849","https://openalex.org/W2460394484"],"related_works":["https://openalex.org/W2147964197","https://openalex.org/W2025096795","https://openalex.org/W2283097280","https://openalex.org/W1500090651","https://openalex.org/W2184852834","https://openalex.org/W1969586315","https://openalex.org/W2098326835","https://openalex.org/W1993483116","https://openalex.org/W3129027717","https://openalex.org/W2730196747"],"abstract_inverted_index":{"The":[0,70,122,144],"present":[1],"study":[2],"is":[3],"aimed":[4],"at":[5,48],"to":[6,61],"investigate":[7],"the":[8,14,49,62,79,101,114,126,152],"antitumor":[9,71],"and":[10,87,94,108,112,132],"antioxidant":[11,95,133],"potentials":[12],"of":[13,17,42,52,67,73,98,118,129,151],"ethanolic":[15],"extract":[16,41],"Leonotis":[18,43],"nepetaefolia":[19,44],"R.Br":[20,45],"(EELN)":[21],"on":[22],"Ehrlich":[23,33],"Ascites":[24,34,104],"Carcinoma":[25,35],"cell":[26,89,110],"lines.":[27],"Tumor":[28,83],"was":[29,46,75],"induced":[30],"intraperitoneally":[31],"using":[32],"cells":[36],"(1X10":[37],"6":[38],"cells/mouse).":[39],"Ethanolic":[40],"administered":[47],"dose":[50,137],"level":[51],"100,":[53],"200":[54],"&":[55],"300":[56],"mg/kg.bw./day":[57],"for":[58],"14":[59],"days":[60],"experimental":[63],"animals":[64],"after":[65],"24h":[66],"tumor":[68,119],"inoculation.":[69],"effect":[72],"EELN":[74,99,123],"assessed":[76],"by":[77],"studying":[78],"parameters":[80],"such":[81],"as":[82],"volume,":[84,106],"PCV,":[85],"viable":[86],"non-viable":[88],"counts,":[90],"life":[91],"span,":[92],"Hematological":[93],"profiles.":[96],"Administration":[97],"decreased":[100],"body":[102],"weight,":[103],"fluid":[105],"PCV":[107],"Viable":[109],"counts":[111],"increased":[113],"mean":[115],"survival":[116],"time":[117],"bearing":[120,142],"animals.":[121],"brought":[124],"back":[125],"altered":[127],"levels":[128,135],"hematological":[130],"parameters,":[131],"enzyme":[134],"in":[136,140],"dependent":[138],"manner":[139],"EAC":[141],"mice.":[143],"results":[145],"obtained":[146],"were":[147],"comparable":[148],"with":[149],"that":[150],"standard":[153],"drug":[154],"5-Flurouracil":[155],"(20mg/kg.bw.).":[156]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}