{"id":"https://openalex.org/W2183086495","doi":null,"title":"INCIDENCE AND PREVALENCE OF CHRONIC IRON POISONING AND IT\u2019S MANAGEMENT: A REVIEW","display_name":"INCIDENCE AND PREVALENCE OF CHRONIC IRON POISONING AND IT\u2019S MANAGEMENT: A REVIEW","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2183086495","mag":"2183086495"},"language":"en","primary_location":{"id":"mag:2183086495","doi":null,"is_oa":false,"landing_page_url":"http://www.ijpbs.net/details.php?article=3763","pdf_url":null,"source":{"id":"https://openalex.org/S2764788474","display_name":"International Journal of Pharma and Bio Sciences","issn_l":"0975-6299","issn":["0975-6299"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4322697007","host_organization_name":"Ubitech Solutions","host_organization_lineage":["https://openalex.org/P4322697007"],"host_organization_lineage_names":["Ubitech Solutions"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Pharma and Bio Sciences","raw_type":null},"volume":null,"type":"review","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046887024","display_name":"Soumya Santra","orcid":"https://orcid.org/0000-0002-9156-7269","observed_orcids":["https://orcid.org/0000-0002-9156-7269"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Soumya Santra","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9156-7269","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100837942","display_name":"Divya Agrawal","orcid":"https://orcid.org/0009-0007-4935-7704","observed_orcids":["https://orcid.org/0009-0007-4935-7704"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Divya Agrawal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5007912802","display_name":"Sanjay Kumarand Sudhanshu Sekhar Mishra","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sanjay Kumarand Sudhanshu Sekhar Mishra","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13481","display_name":"Neurological diseases and metabolism","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/iron-overload","display_name":"iron overload","score":0.9950000047683716},{"id":"https://openalex.org/keywords/hereditary-hemochromatosis","display_name":"hereditary hemochromatosis","score":0.9390000104904175},{"id":"https://openalex.org/keywords/iron-chelators","display_name":"iron chelators","score":0.7850000262260437},{"id":"https://openalex.org/keywords/deferoxamine","display_name":"deferoxamine","score":0.9570000171661377},{"id":"https://openalex.org/keywords/deferiprone","display_name":"deferiprone","score":0.8949999809265137},{"id":"https://openalex.org/keywords/deferasirox","display_name":"deferasirox","score":0.9150000214576721},{"id":"https://openalex.org/keywords/transfusional-iron-overload","display_name":"transfusional iron overload","score":0.7360000014305115},{"id":"https://openalex.org/keywords/thalassemia","display_name":"thalassemia","score":0.8059999942779541},{"id":"https://openalex.org/keywords/sickle-cell-disease","display_name":"sickle cell disease","score":0.9810000061988831},{"id":"https://openalex.org/keywords/myelodysplastic-syndrome","display_name":"myelodysplastic syndrome","score":0.8019999861717224},{"id":"https://openalex.org/keywords/aplastic-anemia","display_name":"aplastic anemia","score":0.9150000214576721},{"id":"https://openalex.org/keywords/iron-metabolism-disorders","display_name":"iron metabolism disorders","score":0.5770000219345093},{"id":"https://openalex.org/keywords/prevalence","display_name":"prevalence","score":0.3799999952316284},{"id":"https://openalex.org/keywords/incidence","display_name":"incidence","score":0.6039999723434448}],"concepts":[{"id":"https://openalex.org/C2781053155","wikidata":"https://www.wikidata.org/wiki/Q5251502","display_name":"Deferasirox","level":3,"score":0.8903042674064636},{"id":"https://openalex.org/C2776517179","wikidata":"https://www.wikidata.org/wiki/Q749664","display_name":"Deferiprone","level":3,"score":0.8830194473266602},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7600821256637573},{"id":"https://openalex.org/C2780844101","wikidata":"https://www.wikidata.org/wiki/Q2380264","display_name":"Ineffective erythropoiesis","level":4,"score":0.7270793318748474},{"id":"https://openalex.org/C2777799968","wikidata":"https://www.wikidata.org/wiki/Q185137","display_name":"Thalassemia","level":2,"score":0.5046623945236206},{"id":"https://openalex.org/C2778248108","wikidata":"https://www.wikidata.org/wiki/Q5445","display_name":"Anemia","level":2,"score":0.4983198642730713},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.48893824219703674},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.47378775477409363},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4648970663547516},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.42645782232284546},{"id":"https://openalex.org/C2776672577","wikidata":"https://www.wikidata.org/wiki/Q419618","display_name":"Deferoxamine","level":2,"score":0.4135546386241913},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3490820825099945},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3467877507209778},{"id":"https://openalex.org/C2779703530","wikidata":"https://www.wikidata.org/wiki/Q837174","display_name":"Erythropoiesis","level":3,"score":0.26735514402389526},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.24182254076004028},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2183086495","doi":null,"is_oa":false,"landing_page_url":"http://www.ijpbs.net/details.php?article=3763","pdf_url":null,"source":{"id":"https://openalex.org/S2764788474","display_name":"International Journal of Pharma and Bio Sciences","issn_l":"0975-6299","issn":["0975-6299"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4322697007","host_organization_name":"Ubitech Solutions","host_organization_lineage":["https://openalex.org/P4322697007"],"host_organization_lineage_names":["Ubitech Solutions"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Pharma and Bio Sciences","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W1493321880","https://openalex.org/W1618001767","https://openalex.org/W1880301439","https://openalex.org/W1969712626","https://openalex.org/W1972151422","https://openalex.org/W1972513910","https://openalex.org/W1978493335","https://openalex.org/W1984418198","https://openalex.org/W1988173388","https://openalex.org/W1995812599","https://openalex.org/W1996425149","https://openalex.org/W2001896561","https://openalex.org/W2012426906","https://openalex.org/W2013564424","https://openalex.org/W2017601661","https://openalex.org/W2021414189","https://openalex.org/W2022460000","https://openalex.org/W2025996143","https://openalex.org/W2026441580","https://openalex.org/W2052473168","https://openalex.org/W2055565597","https://openalex.org/W2063617352","https://openalex.org/W2066394793","https://openalex.org/W2067852287","https://openalex.org/W2073067199","https://openalex.org/W2076446665","https://openalex.org/W2083251039","https://openalex.org/W2100714797","https://openalex.org/W2103778162","https://openalex.org/W2105749655","https://openalex.org/W2114015514","https://openalex.org/W2119692077","https://openalex.org/W2127786964","https://openalex.org/W2134756797","https://openalex.org/W2146033714","https://openalex.org/W2146682670","https://openalex.org/W2151236537","https://openalex.org/W2160648071","https://openalex.org/W2186837499","https://openalex.org/W2186855786","https://openalex.org/W2313234626","https://openalex.org/W2347602582","https://openalex.org/W2408043586","https://openalex.org/W2411088972"],"related_works":["https://openalex.org/W2529561827","https://openalex.org/W1608548877","https://openalex.org/W2434406830","https://openalex.org/W3210535902","https://openalex.org/W2045762866","https://openalex.org/W95673660","https://openalex.org/W2347792160","https://openalex.org/W2065232312","https://openalex.org/W2275443340","https://openalex.org/W1968962523"],"abstract_inverted_index":{"Iron,":[0],"an":[1,151,202],"essential":[2],"nutrient":[3],"causes":[4,61],"serious":[5,12],"diseases":[6,173],"in":[7,82,141,166,168],"deficient":[8],"state.":[9],"But":[10,58],"more":[11],"events":[13],"occur":[14,40],"due":[15,41,75],"to":[16,25,42,76,188],"the":[17,34,59,148,182],"toxicity":[18],"of":[19,29,33,54,62,105,127,150,170,190],"iron":[20,37,46,55,64,73,115,153,171,204],"overload":[21,65,74,172],"and":[22,27,90,100,107,136,157,174,184],"this":[23],"leads":[24],"morbidity":[26,183],"mortality":[28],"a":[30,119,124,144,162],"significant":[31],"population":[32],"world.":[35],"Chronic":[36],"poisoning":[38,116],"can":[39],"daily":[43],"high":[44],"dietary":[45],"intake,":[47],"chronic":[48],"liver":[49],"disease,":[50],"rare":[51],"genetic":[52],"disorders":[53],"metabolism,":[56],"etc.":[57],"commonest":[60],"severe":[63],"are":[66,159,209],"Hereditary":[67],"Haemochromatosis,":[68],"Massive":[69],"ineffective":[70],"erythropoiesis,":[71],"secondary":[72],"frequent":[77,193],"repeated":[78],"red":[79,194],"cell":[80,88,109,195],"transfusion":[81],"congenital":[83],"anaemias":[84,93],"(e.g.":[85,94],"\u03b2-Thlassaemia,":[86],"Sickle":[87,108],"anaemia)":[89],"Acquired":[91],"refractory":[92],"myelodysplasia,":[95],"aplastic":[96],"anaemia).":[97],"In":[98],"India":[99],"South":[101],"-East":[102],"Asia,":[103],"prevalence":[104],"Thalassaemia":[106],"anemia":[110],"is":[111],"indeed":[112,177],"alarming.":[113],"Though,":[114],"has":[117,175],"been":[118,134],"health":[120],"concern":[121],"for":[122,201],"quite":[123],"long":[125],"period":[126],"time,":[128],"only":[129],"three":[130],"drugs":[131,208],"could":[132],"have":[133],"developed":[135],"put":[137],"into":[138,211],"practice.":[139],"Even":[140],"2014,":[142],"not":[143],"single":[145,163],"agent":[146],"fulfils":[147],"requisites":[149],"ideal":[152,203],"chelator.":[154],"Desferrioxamine,":[155],"Deferiprone":[156],"Deferasirox":[158],"used":[160],"as":[161,206],"drug":[164],"or":[165],"combinations":[167],"cases":[169],"shown":[176],"promising":[178],"results":[179],"by":[180],"decreasing":[181],"adding":[185],"quality":[186],"years":[187],"life":[189],"patients":[191],"undergoing":[192],"transfusions.":[196],"However":[197],"we":[198],"still":[199],"wait":[200],"chelator":[205],"few":[207],"already":[210],"phase":[212],"II":[213],"clinical":[214],"trials.":[215]},"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}