{"id":"https://openalex.org/W2182894875","doi":null,"title":"Comparative Effect of Aqueous Extract of P. Guajava Leaves and Ascorbic Acid on Serum Sex Hormones Levels in Male and Female Rats","display_name":"Comparative Effect of Aqueous Extract of P. Guajava Leaves and Ascorbic Acid on Serum Sex Hormones Levels in Male and Female Rats","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2182894875","mag":"2182894875"},"language":"en","primary_location":{"id":"mag:2182894875","doi":null,"is_oa":true,"landing_page_url":"https://www.cabdirect.org/abstracts/20103155645.html","pdf_url":null,"source":{"id":"https://openalex.org/S2764653592","display_name":"The Journal of applied sciences research","issn_l":"2423-4400","issn":["2423-4400"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u0098The \u009cJournal of applied sciences research","raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.cabdirect.org/abstracts/20103155645.html","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035502059","display_name":"F.E. Uboh","orcid":"https://orcid.org/0000-0002-9546-4363","observed_orcids":["https://orcid.org/0000-0002-9546-4363"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F.E. Uboh","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9546-4363","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113605297","display_name":"E. E. Edet","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E. E. Edet","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109385244","display_name":"Mbeh Ubana Eteng","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M.U. Eteng","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5108478240","display_name":"E.U. Eyong","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E.U. Eyong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2912,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.80649381,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":null,"issue":null,"first_page":"275","last_page":"279"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14360","display_name":"Psidium guajava Extracts and Applications","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14360","display_name":"Psidium guajava Extracts and Applications","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12298","display_name":"Phytochemicals and Medicinal Plants","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/guava","display_name":"guava","score":0.9959999918937683},{"id":"https://openalex.org/keywords/vitamin-c","display_name":"vitamin C","score":0.9990000128746033},{"id":"https://openalex.org/keywords/sex-hormones","display_name":"sex hormones","score":0.8859999775886536},{"id":"https://openalex.org/keywords/follicle-stimulating-hormone","display_name":"follicle-stimulating hormone","score":0.7820000052452087},{"id":"https://openalex.org/keywords/luteinizing-hormone","display_name":"luteinizing hormone","score":1.0},{"id":"https://openalex.org/keywords/estradiol","display_name":"estradiol","score":0.996999979019165},{"id":"https://openalex.org/keywords/progesterone","display_name":"progesterone","score":0.9990000128746033},{"id":"https://openalex.org/keywords/testosterone","display_name":"testosterone","score":1.0},{"id":"https://openalex.org/keywords/reproductive-function","display_name":"reproductive function","score":0.8159999847412109},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.6830000281333923},{"id":"https://openalex.org/keywords/ethnomedicinal-plants","display_name":"ethnomedicinal plants","score":0.765999972820282},{"id":"https://openalex.org/keywords/reproductive-disorders","display_name":"reproductive disorders","score":0.47200000286102295}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8085561990737915},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.8053251504898071},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.7928931713104248},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7593982815742493},{"id":"https://openalex.org/C2778575703","wikidata":"https://www.wikidata.org/wiki/Q50265477","display_name":"Luteinizing hormone","level":3,"score":0.7025961875915527},{"id":"https://openalex.org/C2986274086","wikidata":"https://www.wikidata.org/wiki/Q199678","display_name":"Ascorbic acid","level":2,"score":0.6199978590011597},{"id":"https://openalex.org/C57992300","wikidata":"https://www.wikidata.org/wiki/Q2066956","display_name":"Potency","level":3,"score":0.5878620147705078},{"id":"https://openalex.org/C2779279165","wikidata":"https://www.wikidata.org/wiki/Q200774","display_name":"Follicle-stimulating hormone","level":4,"score":0.522411584854126},{"id":"https://openalex.org/C2993907526","wikidata":"https://www.wikidata.org/wiki/Q1259977","display_name":"Aqueous extract","level":2,"score":0.4471198320388794},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3885210454463959},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.34366971254348755},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.1133413016796112},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.0},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2182894875","doi":null,"is_oa":true,"landing_page_url":"https://www.cabdirect.org/abstracts/20103155645.html","pdf_url":null,"source":{"id":"https://openalex.org/S2764653592","display_name":"The Journal of applied sciences research","issn_l":"2423-4400","issn":["2423-4400"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u0098The \u009cJournal of applied sciences research","raw_type":null}],"best_oa_location":{"id":"mag:2182894875","doi":null,"is_oa":true,"landing_page_url":"https://www.cabdirect.org/abstracts/20103155645.html","pdf_url":null,"source":{"id":"https://openalex.org/S2764653592","display_name":"The Journal of applied sciences research","issn_l":"2423-4400","issn":["2423-4400"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u0098The \u009cJournal of applied sciences research","raw_type":null},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"},{"id":"https://metadata.un.org/sdg/2","score":0.40450000762939453,"display_name":"Zero hunger"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.6100000143051147,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W1967033633","https://openalex.org/W1975064171","https://openalex.org/W1975177731","https://openalex.org/W1978940653","https://openalex.org/W1982903663","https://openalex.org/W1986185261","https://openalex.org/W1997958925","https://openalex.org/W2006124885","https://openalex.org/W2038527370","https://openalex.org/W2040523961","https://openalex.org/W2050023717","https://openalex.org/W2057642417","https://openalex.org/W2088717607","https://openalex.org/W2090572655","https://openalex.org/W2105751910","https://openalex.org/W2144307786","https://openalex.org/W2151104181","https://openalex.org/W2158507076","https://openalex.org/W2160691981","https://openalex.org/W2185676398","https://openalex.org/W2329219940","https://openalex.org/W2413084414","https://openalex.org/W4241780994"],"related_works":["https://openalex.org/W4386396057","https://openalex.org/W3212316131","https://openalex.org/W4412836552","https://openalex.org/W2184202167","https://openalex.org/W4411311560","https://openalex.org/W3172870784","https://openalex.org/W4387482007","https://openalex.org/W2328358203","https://openalex.org/W104086371","https://openalex.org/W2466925408"],"abstract_inverted_index":{"Psidium":[0],"guajava":[1,26],"has":[2],"a":[3,103,221],"rich":[4],"ethnomedicinal":[5],"history,":[6],"particularly":[7],"in":[8,97,109,115,119,134,141,157,164,190,200,211,224,240],"the":[9,49,90,110,174,179,197,208,226,235],"treatment":[10,75],"of":[11,21,24,58,70,76,93,176,181,188,228],"various":[12,253],"gastrointestinal":[13],"disorders.":[14],"In":[15],"this":[16,71],"study,":[17],"200mg/kg":[18],"body":[19],"weight":[20],"aqueous":[22],"extract":[23],"P.":[25],"leaves(AEPGL)":[27],"and":[28,36,51,66,80,95,99,102,113,117,125,130,136,148,153,159,192,195,233],"ascorbic":[29],"acid(vitC)":[30],"were":[31],"administered":[32],"orally":[33],"to":[34,43],"male":[35,50,98,191,201,241],"female":[37,52,100,193,212,243],"rats":[38,77],"daily,":[39],"for":[40,250],"30":[41],"days,":[42],"assess":[44],"their":[45],"respective":[46],"effect":[47,85,175,236],"on":[48,89,178],"reproductive":[53,254],"functions,":[54],"using":[55],"serum":[56,91,111,123,146],"levels":[57,92,127,150,180],"follicle":[59],"stimulating":[60,225],"hormone(FSH),":[61],"luteinizing":[62],"hormone(LH),":[63],"estradiol,":[64],"progesterone":[65,114,126,149],"testosterone.":[67],"The":[68],"results":[69],"study":[72],"showed":[73],"that":[74,173,187,196,218,234],"with":[78,252],"AEPGL":[79,121,177,219,246],"vitC,":[81,232],"respectively,":[82,133,156],"had":[83],"insignificant":[84],"(P":[86,106],"$":[87],"0.05)":[88,108],"FSH":[94],"LH":[96],"rats,":[101,194],"significant":[104,239],"increase":[105,199,210],"#":[107],"estradiol":[112,124,147],"females,":[116,135,158],"testosterone":[118,137,160],"males.":[120],"increased":[122,145],"by":[128,138,151,161],"17.6":[129],"34.6":[131],"percents,":[132,155],"38.6":[139],"percent":[140,163],"males,":[142],"while":[143],"vitC":[144,189],"15.2":[152],"30.0":[154],"28.0":[162],"males":[165,251],"rats.":[166],"From":[167],"these":[168,182],"results,":[169],"it":[170],"was":[171,184,204],"observed":[172],"hormones":[183,203,230],"higher":[185,206,222],"than":[186,207,231,242],"percentage":[198,209],"sex":[202,213,229],"significantly":[205],"hormones.":[214],"These":[215],"observations":[216],"indicated":[217],"possess":[220],"potency":[223],"secretion":[227],"is":[237],"more":[238],"rats;":[244],"hence,":[245],"may":[247],"be":[248],"recommended":[249],"dysfunctions.":[255]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2016-06-24T00:00:00"}