{"id":"https://openalex.org/W2182893669","doi":null,"title":"DISRUPTION OF GAL1 GENE IN SACCHAROMYCES CEREVISIAE LEADS TO HIGHER ETHANOL PRODUCTION","display_name":"DISRUPTION OF GAL1 GENE IN SACCHAROMYCES CEREVISIAE LEADS TO HIGHER ETHANOL PRODUCTION","publication_year":2004,"publication_date":"2004-07-01","ids":{"openalex":"https://openalex.org/W2182893669","mag":"2182893669"},"language":"en","primary_location":{"id":"mag:2182893669","doi":null,"is_oa":false,"landing_page_url":"http://www.ijbiotech.com/article_6908_8ffa66790224dab6eb3d7b2061bef2b4.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2484379123","display_name":"Iranian Journal of Biotechnology","issn_l":"1728-3043","issn":["1728-3043","2322-2921"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4327876842","host_organization_name":"Armenian Green Publishing Co.","host_organization_lineage":["https://openalex.org/P4327876842"],"host_organization_lineage_names":["Armenian Green Publishing Co."],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Iranian Journal of Biotechnology","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053713032","display_name":"Abbas Rezaee","orcid":"https://orcid.org/0000-0001-5042-2963","observed_orcids":["https://orcid.org/0000-0001-5042-2963"]},"institutions":[{"id":"https://openalex.org/I1516879","display_name":"Tarbiat Modares University","ror":"https://ror.org/03mwgfy56","country_code":"IR","type":"education","lineage":["https://openalex.org/I1516879"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Abbas Rezaee","raw_affiliation_strings":["Faculty of Medical Sciences, Tarbiat Modarres University, Tehran, I.R. Iran,"],"raw_orcid":"https://orcid.org/0000-0001-5042-2963","affiliations":[{"raw_affiliation_string":"Faculty of Medical Sciences, Tarbiat Modarres University, Tehran, I.R. Iran,","institution_ids":["https://openalex.org/I1516879"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038583036","display_name":"Hyun Ah Kang","orcid":"https://orcid.org/0000-0002-3722-525X","observed_orcids":["https://orcid.org/0000-0002-3722-525X"]},"institutions":[{"id":"https://openalex.org/I73616290","display_name":"Korea Research Institute of Bioscience and Biotechnology","ror":"https://ror.org/03ep23f07","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210144908","https://openalex.org/I4387152098","https://openalex.org/I73616290"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hyun Ah Kang","raw_affiliation_strings":["Microbial Metabolic Engineering#N#Research Units, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Taejon, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbial Metabolic Engineering#N#Research Units, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Taejon, South Korea","institution_ids":["https://openalex.org/I73616290"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103988760","display_name":"Sang Ki Rhee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I73616290","display_name":"Korea Research Institute of Bioscience and Biotechnology","ror":"https://ror.org/03ep23f07","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210144908","https://openalex.org/I4387152098","https://openalex.org/I73616290"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sang Ki Rhee","raw_affiliation_strings":["Microbial Metabolic Engineering#N#Research Units, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Taejon, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbial Metabolic Engineering#N#Research Units, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Taejon, South Korea","institution_ids":["https://openalex.org/I73616290"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2","issue":"3","first_page":"177","last_page":"182"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.6420999765396118,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.6420999765396118,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10171","display_name":"Biofuel production and bioconversion","score":0.20100000500679016,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.14249999821186066,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/galactokinase","display_name":"galactokinase","score":0.8479999899864197},{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.9240000247955322},{"id":"https://openalex.org/keywords/ethanol-production","display_name":"ethanol production","score":0.8560000061988831},{"id":"https://openalex.org/keywords/deletion-mutants","display_name":"deletion mutants","score":0.7149999737739563},{"id":"https://openalex.org/keywords/galactose-utilization","display_name":"galactose utilization","score":0.8759999871253967},{"id":"https://openalex.org/keywords/glucose-utilization","display_name":"glucose utilization","score":0.8709999918937683},{"id":"https://openalex.org/keywords/biomass-production","display_name":"biomass production","score":0.8069999814033508},{"id":"https://openalex.org/keywords/aerobic-cultivation","display_name":"aerobic cultivation","score":0.5320000052452087},{"id":"https://openalex.org/keywords/fermentative-growth","display_name":"fermentative growth","score":0.7210000157356262}],"concepts":[{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.783159077167511},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.7825615406036377},{"id":"https://openalex.org/C2778173381","wikidata":"https://www.wikidata.org/wiki/Q66589593","display_name":"Galactose","level":2,"score":0.672956645488739},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.6139698028564453},{"id":"https://openalex.org/C196493046","wikidata":"https://www.wikidata.org/wiki/Q24768242","display_name":"Galactokinase","level":4,"score":0.5683301687240601},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5558004379272461},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5226447582244873},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.5144327282905579},{"id":"https://openalex.org/C2780161600","wikidata":"https://www.wikidata.org/wiki/Q153","display_name":"Ethanol","level":2,"score":0.44641056656837463},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3474906086921692},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.045691877603530884}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2182893669","doi":null,"is_oa":false,"landing_page_url":"http://www.ijbiotech.com/article_6908_8ffa66790224dab6eb3d7b2061bef2b4.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2484379123","display_name":"Iranian Journal of Biotechnology","issn_l":"1728-3043","issn":["1728-3043","2322-2921"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4327876842","host_organization_name":"Armenian Green Publishing Co.","host_organization_lineage":["https://openalex.org/P4327876842"],"host_organization_lineage_names":["Armenian Green Publishing Co."],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Iranian Journal of Biotechnology","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1602727746","https://openalex.org/W1692352656","https://openalex.org/W1760594148","https://openalex.org/W1763161027","https://openalex.org/W1842111497","https://openalex.org/W1979595221","https://openalex.org/W1991979194","https://openalex.org/W2006053013","https://openalex.org/W2010844946","https://openalex.org/W2039609168","https://openalex.org/W2058720930","https://openalex.org/W2065444211","https://openalex.org/W2067863011","https://openalex.org/W2086660631","https://openalex.org/W2102470371","https://openalex.org/W2124157676","https://openalex.org/W2135998024","https://openalex.org/W2149700055","https://openalex.org/W2156663873","https://openalex.org/W2159958449","https://openalex.org/W2160877304","https://openalex.org/W2167498867"],"related_works":["https://openalex.org/W190936043","https://openalex.org/W2056072359","https://openalex.org/W2029271827","https://openalex.org/W2342851745","https://openalex.org/W2483831556","https://openalex.org/W2312687894","https://openalex.org/W2123895283","https://openalex.org/W2085055921","https://openalex.org/W2088701437","https://openalex.org/W2052047744"],"abstract_inverted_index":{"GAL":[0],"gene":[1,43,87],"family":[2],"is":[3],"a":[4,18,92,104],"set":[5],"of":[6,25,41,54,84],"structural":[7],"and":[8,68,97,109],"regulatory":[9],"genes":[10],"that":[11,117],"enables":[12],"cells":[13],"to":[14,90],"utilize":[15],"galactose":[16,27],"as":[17],"carbon":[19],"source":[20],"in":[21,79,106,138],"Saccharomyces":[22],"cerevisiae.":[23],"Phosphorylation":[24],"intracellular":[26],"can":[28],"be":[29],"catalyzed":[30],"by":[31,34,47,120],"galactokinase":[32],"(encoded":[33],"GAL1":[35,42,55,70,73,86,101,121],"gene).":[36],"In":[37],"this":[38],"study":[39],"role":[40],"on":[44,95],"ethanol":[45,98,111,139],"production":[46],"S.":[48],"cerevisiae":[49],"together":[50],"with":[51,65,133],"physiological":[52],"characterization":[53],"mutant":[56,74,102],"strain":[57,67,75],"was":[58,62,88],"studied.":[59],"Aerobic":[60],"cultivation":[61],"carried":[63],"out":[64],"wild-type":[66],"the":[69,85,114],"mutant.":[71],"The":[72,100],"displayed":[76],"fermentative":[77],"growth":[78,107],"early":[80],"exponential":[81],"phase.":[82],"Deletion":[83],"shown":[89],"have":[91],"major":[93],"impact":[94],"biomass":[96,126],"formation.":[99],"exhibited":[103],"decrease":[105],"rate":[108],"increased":[110],"production.":[112,140],"Furthermore":[113],"results":[115],"showed":[116],"glucose":[118],"consumption":[119],"mutants":[122],"did":[123],"not":[124],"favor":[125],"formation,":[127],"rather":[128],"cause":[129],"excessive":[130],"respiro-fermentative":[131],"metabolism,":[132],"whereas":[134],"could":[135],"linear":[136],"increase":[137]},"counts_by_year":[],"updated_date":"2026-08-12T21:12:35.861297","created_date":"2016-06-24T00:00:00"}