{"id":"https://openalex.org/W2182484497","doi":null,"title":"Root resorption associated with orthodontic force in IL-1Beta knockout mouse.","display_name":"Root resorption associated with orthodontic force in IL-1Beta knockout mouse.","publication_year":2004,"publication_date":"2004-12-01","ids":{"openalex":"https://openalex.org/W2182484497","mag":"2182484497","pmid":"https://pubmed.ncbi.nlm.nih.gov/15758271"},"language":"en","primary_location":{"id":"pmid:15758271","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15758271","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of musculoskeletal & neuronal interactions","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023489459","display_name":"Riyad A. Al-Qawasmi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R A Al-Qawasmi","raw_affiliation_strings":["Indiana University School of Dentistry, Indianapolis, IN 46202, USA. ralqawas@iupui.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indiana University School of Dentistry, Indianapolis, IN 46202, USA. ralqawas@iupui.edu","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I55769427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067246712","display_name":"James Kennedy Hartsfield","orcid":"https://orcid.org/0000-0001-9117-5508","observed_orcids":["https://orcid.org/0000-0001-9117-5508"]},"institutions":[{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J K Hartsfield","raw_affiliation_strings":["Indiana-University Purdue-University Indianapolis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indiana-University Purdue-University Indianapolis","institution_ids":["https://openalex.org/I55769427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067246712","display_name":"James Kennedy Hartsfield","orcid":"https://orcid.org/0000-0001-9117-5508","observed_orcids":["https://orcid.org/0000-0001-9117-5508"]},"institutions":[{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J K Hartsfield","raw_affiliation_strings":["Indiana-University Purdue-University Indianapolis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indiana-University Purdue-University Indianapolis","institution_ids":["https://openalex.org/I55769427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016759211","display_name":"Eric T. Everett","orcid":"https://orcid.org/0000-0001-7801-5278","observed_orcids":["https://orcid.org/0000-0001-7801-5278"]},"institutions":[{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E T Everett","raw_affiliation_strings":["Indiana-University Purdue-University Indianapolis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indiana-University Purdue-University Indianapolis","institution_ids":["https://openalex.org/I55769427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110155937","display_name":"Marjorie R. Weaver","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M R Weaver","raw_affiliation_strings":["Medical & Molecular Genetics"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical & Molecular Genetics","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048034644","display_name":"Tatiana Foroud","orcid":"https://orcid.org/0000-0002-5549-2212","observed_orcids":["https://orcid.org/0000-0002-5549-2212"]},"institutions":[{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T M Foroud","raw_affiliation_strings":["Indiana-University Purdue-University Indianapolis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indiana-University Purdue-University Indianapolis","institution_ids":["https://openalex.org/I55769427"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076082310","display_name":"Wilbur Eugene Roberts","orcid":"https://orcid.org/0000-0002-1396-2466","observed_orcids":["https://orcid.org/0000-0002-1396-2466","https://orcid.org/0000-0003-2795-1861"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W E Roberts","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.411,"has_fulltext":false,"cited_by_count":43,"citation_normalized_percentile":{"value":0.88850918,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"4","issue":"4","first_page":"383","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10356","display_name":"Orthodontics and Dentofacial Orthopedics","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/3505","display_name":"Orthodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10356","display_name":"Orthodontics and Dentofacial Orthopedics","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/3505","display_name":"Orthodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.00989999994635582,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/root-resorption","display_name":"root resorption","score":0.8939999938011169},{"id":"https://openalex.org/keywords/orthodontic-tooth-movement","display_name":"orthodontic tooth movement","score":0.9419999718666077},{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.9570000171661377},{"id":"https://openalex.org/keywords/bone-resorption","display_name":"bone resorption","score":0.8650000095367432},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.6510000228881836},{"id":"https://openalex.org/keywords/periodontium","display_name":"periodontium","score":0.8040000200271606},{"id":"https://openalex.org/keywords/gingival-crevicular-fluid","display_name":"gingival crevicular fluid","score":0.9760000109672546}],"concepts":[{"id":"https://openalex.org/C2778703501","wikidata":"https://www.wikidata.org/wiki/Q7824277","display_name":"Root resorption","level":3,"score":0.6359273195266724},{"id":"https://openalex.org/C182704531","wikidata":"https://www.wikidata.org/wiki/Q1364740","display_name":"Knockout mouse","level":3,"score":0.6338523626327515},{"id":"https://openalex.org/C673006","wikidata":"https://www.wikidata.org/wiki/Q4941581","display_name":"Bone resorption","level":2,"score":0.6228111386299133},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5393187403678894},{"id":"https://openalex.org/C146562846","wikidata":"https://www.wikidata.org/wiki/Q96649518","display_name":"Resorption","level":2,"score":0.5247117280960083},{"id":"https://openalex.org/C74172505","wikidata":"https://www.wikidata.org/wiki/Q194908","display_name":"Interleukin","level":3,"score":0.49646860361099243},{"id":"https://openalex.org/C3020625565","wikidata":"https://www.wikidata.org/wiki/Q194908","display_name":"Interleukin 1\u03b2","level":4,"score":0.49325889348983765},{"id":"https://openalex.org/C41868710","wikidata":"https://www.wikidata.org/wiki/Q540092","display_name":"Periodontal fiber","level":2,"score":0.4603964686393738},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.4566366970539093},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.4322967231273651},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.33294764161109924},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2832862138748169},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.10274538397789001}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007375","descriptor_name":"Interleukin-1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007568","descriptor_name":"Jaw","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007568","descriptor_name":"Jaw","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D007568","descriptor_name":"Jaw","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009967","descriptor_name":"Orthodontic Appliances","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D012391","descriptor_name":"Root Resorption","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012391","descriptor_name":"Root Resorption","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012391","descriptor_name":"Root Resorption","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D013314","descriptor_name":"Stress, Mechanical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014092","descriptor_name":"Tooth Root","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014092","descriptor_name":"Tooth Root","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014092","descriptor_name":"Tooth Root","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:15758271","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15758271","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of musculoskeletal & neuronal interactions","raw_type":"Journal Article"},{"id":"mag:2182484497","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15758271","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1973786540","https://openalex.org/W1975406338","https://openalex.org/W1978495122","https://openalex.org/W1989080833","https://openalex.org/W2080871180","https://openalex.org/W2130348215","https://openalex.org/W2155850408","https://openalex.org/W2172017373"],"related_works":["https://openalex.org/W1554271555","https://openalex.org/W2418482413","https://openalex.org/W3129944895","https://openalex.org/W7029105429","https://openalex.org/W2925111125","https://openalex.org/W2143097726","https://openalex.org/W2371288764","https://openalex.org/W2765543804","https://openalex.org/W1975406338","https://openalex.org/W1978495122"],"abstract_inverted_index":{"Interleukin-1,":[0],"the":[1,29,47],"term":[2],"which":[3],"encompasses":[4],"three":[5],"differentpolypeptides:":[6],"IL-1\u00b7,":[7],"IL-1\u201a":[8,27],"and":[9,32],"IL-1ra,":[10],"has":[11],"been":[12],"shown":[13],"to":[14],"bea":[15],"potent":[16],"stimulus":[17],"for":[18],"bone":[19],"resorption.":[20],"The":[21],"presence":[22],"of":[23,26,35,43],"ele-vated":[24],"levels":[25],"in":[28,46],"periodontal":[30],"tissue":[31],"gingivalcrevicular":[33],"fluids":[34],"patients":[36],"undergoing":[37],"orthodontic":[38],"toothmovement":[39],"implicate":[40],"a":[41],"role":[42],"this":[44],"cytokine":[45],"orthodon-tically":[48],"induced":[49],"tooth":[50],"movement":[51]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}