{"id":"https://openalex.org/W2182303395","doi":null,"title":"Human NKT cells in health and disease","display_name":"Human NKT cells in health and disease","publication_year":2003,"publication_date":"2003-01-01","ids":{"openalex":"https://openalex.org/W2182303395","mag":"2182303395"},"language":"en","primary_location":{"id":"mag:2182303395","doi":null,"is_oa":false,"landing_page_url":"http://www.inmunologia.org/Upload/Articles/6/1/612.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024647317","display_name":"Raquel Tarazona","orcid":"https://orcid.org/0000-0002-2926-6377","observed_orcids":["https://orcid.org/0000-0002-2926-6377"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Raquel Tarazona","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2926-6377","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029682067","display_name":"Olga DelaRosa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Olga DelaRosa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070132463","display_name":"Esther Peralbo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Esther Peralbo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110165442","display_name":"Jos\u00e9 Pe\u00f1a","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Pe\u00f1a","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013229327","display_name":"Rafael Solana","orcid":"https://orcid.org/0000-0001-8985-0295","observed_orcids":["https://orcid.org/0000-0001-8985-0295"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rafael Solana","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8985-0295","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5109274589","display_name":"Reina Sof\u00eda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Reina Sof\u00eda","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9452999830245972,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9452999830245972,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.038100000470876694,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nkt-cells","display_name":"NKT cells","score":0.9079999923706055},{"id":"https://openalex.org/keywords/cd1d","display_name":"CD1d","score":0.675000011920929},{"id":"https://openalex.org/keywords/glycolipid-antigen-presentation","display_name":"glycolipid antigen presentation","score":0.8379999995231628},{"id":"https://openalex.org/keywords/cd161","display_name":"CD161","score":0.8730000257492065},{"id":"https://openalex.org/keywords/nk1-1","display_name":"NK1.1","score":0.9929999709129333},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.9559999704360962},{"id":"https://openalex.org/keywords/il-4","display_name":"IL-4","score":0.996999979019165},{"id":"https://openalex.org/keywords/immune-regulation","display_name":"immune regulation","score":0.9120000004768372},{"id":"https://openalex.org/keywords/autoimmune-disease","display_name":"autoimmune disease","score":0.6629999876022339},{"id":"https://openalex.org/keywords/antitumor-immunity","display_name":"antitumor immunity","score":0.9120000004768372},{"id":"https://openalex.org/keywords/infection-immunity","display_name":"infection immunity","score":0.46799999475479126}],"concepts":[{"id":"https://openalex.org/C139563560","wikidata":"https://www.wikidata.org/wiki/Q224930","display_name":"Natural killer T cell","level":4,"score":0.5485261082649231},{"id":"https://openalex.org/C2778607024","wikidata":"https://www.wikidata.org/wiki/Q4216825","display_name":"CD1D","level":5,"score":0.41124388575553894},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4097057580947876},{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.3763258457183838},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3224349319934845},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.3178260326385498},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.29386264085769653},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.2779400944709778},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.11173632740974426}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2182303395","doi":null,"is_oa":false,"landing_page_url":"http://www.inmunologia.org/Upload/Articles/6/1/612.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":108,"referenced_works":["https://openalex.org/W90445304","https://openalex.org/W196365333","https://openalex.org/W1480981145","https://openalex.org/W1513074631","https://openalex.org/W1523753658","https://openalex.org/W1538328956","https://openalex.org/W1542749101","https://openalex.org/W1560455987","https://openalex.org/W1568297835","https://openalex.org/W1580852520","https://openalex.org/W1594342761","https://openalex.org/W1595465958","https://openalex.org/W1599148944","https://openalex.org/W1623029084","https://openalex.org/W1632817771","https://openalex.org/W1761643547","https://openalex.org/W1781937061","https://openalex.org/W1806757355","https://openalex.org/W1828603026","https://openalex.org/W1856377922","https://openalex.org/W1891679949","https://openalex.org/W1898965970","https://openalex.org/W1970548110","https://openalex.org/W1973076242","https://openalex.org/W1975183474","https://openalex.org/W1978757502","https://openalex.org/W1979727939","https://openalex.org/W1981296364","https://openalex.org/W1982538054","https://openalex.org/W1982727887","https://openalex.org/W1984510622","https://openalex.org/W1985694361","https://openalex.org/W1987308052","https://openalex.org/W1987490119","https://openalex.org/W1995217592","https://openalex.org/W1996826311","https://openalex.org/W1999281277","https://openalex.org/W2000115037","https://openalex.org/W2004318032","https://openalex.org/W2010528006","https://openalex.org/W2013255473","https://openalex.org/W2014525331","https://openalex.org/W2029036039","https://openalex.org/W2035054132","https://openalex.org/W2035100579","https://openalex.org/W2037915406","https://openalex.org/W2042212610","https://openalex.org/W2046549183","https://openalex.org/W2046553479","https://openalex.org/W2054081548","https://openalex.org/W2055971070","https://openalex.org/W2057366474","https://openalex.org/W2059313909","https://openalex.org/W2060688316","https://openalex.org/W2064495692","https://openalex.org/W2065709904","https://openalex.org/W2069102137","https://openalex.org/W2072948111","https://openalex.org/W2074937083","https://openalex.org/W2078404671","https://openalex.org/W2079985879","https://openalex.org/W2081913102","https://openalex.org/W2083051515","https://openalex.org/W2089110736","https://openalex.org/W2089476436","https://openalex.org/W2090297133","https://openalex.org/W2093497258","https://openalex.org/W2095967285","https://openalex.org/W2098405100","https://openalex.org/W2100710702","https://openalex.org/W2101543719","https://openalex.org/W2102621929","https://openalex.org/W2102777081","https://openalex.org/W2106046140","https://openalex.org/W2116180955","https://openalex.org/W2116287908","https://openalex.org/W2118122375","https://openalex.org/W2121895986","https://openalex.org/W2124491055","https://openalex.org/W2130295685","https://openalex.org/W2131170047","https://openalex.org/W2134168246","https://openalex.org/W2137499920","https://openalex.org/W2138453840","https://openalex.org/W2138869419","https://openalex.org/W2139250003","https://openalex.org/W2139553339","https://openalex.org/W2140886712","https://openalex.org/W2144512464","https://openalex.org/W2144821901","https://openalex.org/W2146472549","https://openalex.org/W2148219135","https://openalex.org/W2148993694","https://openalex.org/W2149349606","https://openalex.org/W2149389294","https://openalex.org/W2150967155","https://openalex.org/W2151297187","https://openalex.org/W2153437241","https://openalex.org/W2159312193","https://openalex.org/W2160420882","https://openalex.org/W2160613479","https://openalex.org/W2161307276","https://openalex.org/W2161997696","https://openalex.org/W2167094013","https://openalex.org/W2168419126","https://openalex.org/W2171356028","https://openalex.org/W2171708934","https://openalex.org/W2318334792"],"related_works":["https://openalex.org/W2581717299","https://openalex.org/W2085387086","https://openalex.org/W7120365498","https://openalex.org/W2065709904","https://openalex.org/W90445304","https://openalex.org/W2380421869","https://openalex.org/W1954055770","https://openalex.org/W7095598463","https://openalex.org/W1594342761","https://openalex.org/W7008409135"],"abstract_inverted_index":{"RESUMEN":[0],"Las":[1,23],"celulas":[2,24,61,72,115,125,154,165],"T":[3,20],"\u00abNatural":[4],"killer\u00bb":[5],"(NKT)":[6],"constituyen":[7],"un":[8,92],"nuevo":[9],"linaje":[10],"de":[11,17,32,56,86,99,106,114,123,145,152,163,169,177,180],"linfocitos":[12,19],"fenotipicamente":[13],"y":[14,47,66,90,134,150,184],"funcionalmente":[15],"diferente":[16],"los":[18,40,57],"\u03b1/\u03b2":[21],"convencionales.":[22],"NKT":[25,73,116,126,155],"se":[26],"caracterizan":[27],"por":[28,39,53],"una":[29],"expresion":[30,55],"restringida":[31],"la":[33,54,87,97,121,128,143,161,167,170,175,178,186],"cadena":[34],"\u03b1":[35],"del":[36],"TCR":[37],"codificada":[38],"segmentos":[41],"genicos":[42],"V\u03b124/J\u03b1Q":[43],"en":[44,49,64,68,83,127,136,147,156,166,174,185],"seres":[45],"humanos":[46,65],"V\u03b114/J\u03b1281":[48],"ratones,":[50],"asi":[51],"como":[52,75],"receptores":[58],"asociados":[59],"a":[60,131],"NK,":[62],"CD161":[63],"NK1.1":[67],"ratones.":[69],"Tanto":[70],"las":[71,76,124,153,181],"humanas":[74],"murinas":[77],"interaccionan":[78],"especificamente":[79],"con":[80],"glicolipidos":[81],"presentados":[82],"el":[84,104,148],"contexto":[85],"molecula":[88],"CD1d":[89],"juegan":[91],"papel":[93],"inmunorregulador":[94],"importante":[95],"mediante":[96],"produccion":[98],"Interferon-\u03b3":[100],"e":[101],"Interleuquina-4.":[102],"Recientemente,":[103],"desarrollo":[105],"ratones":[107],"manipulados":[108],"geneticamente,":[109],"que":[110,159],"presentan":[111],"perdida":[112],"selectiva":[113],"V\u03b114,":[117],"ha":[118,141],"permitido":[119],"elucidar":[120],"funcion":[122,151],"respuesta":[129,171],"frente":[130],"diferentes":[132,157],"infecciones":[133],"tumores":[135],"diversos":[137],"modelos":[138],"experimentales.":[139],"Se":[140],"demostrado":[142],"existencia":[144],"cambios":[146],"numero":[149],"enfermedades":[158],"apoyan":[160],"participacion":[162],"estas":[164],"regulacion":[168,176],"inmune":[172],"particularmente":[173],"homeostasis":[179],"respuestas":[182],"autoinmunes":[183],"inmunidad":[187],"tumoral.":[188]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2016-06-24T00:00:00"}
