{"id":"https://openalex.org/W2181869417","doi":null,"title":"Insulin Independence after Fetal Liver-Derived Cell Suspension Allotransplantation in Patients with Type 1 Diabetes: A Pilot Study","display_name":"Insulin Independence after Fetal Liver-Derived Cell Suspension Allotransplantation in Patients with Type 1 Diabetes: A Pilot Study","publication_year":2015,"publication_date":"2015-10-21","ids":{"openalex":"https://openalex.org/W2181869417","mag":"2181869417"},"language":"en","primary_location":{"id":"pmh:oai:doaj.org/article:10842c5347324cac927d23d3be157f91","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/10842c5347324cac927d23d3be157f91","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Iranian Journal of Public Health, Vol 44, Iss Supple 2 (2015)","raw_type":"article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://ijph.tums.ac.ir/index.php/ijph/article/download/4912/4487","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058968548","display_name":"Maryam Ghodsi","orcid":"https://orcid.org/0000-0001-8940-3970","observed_orcids":["https://orcid.org/0000-0001-8940-3970"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maryam Ghodsi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8940-3970","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055093325","display_name":"Farzaneh Abbasi","orcid":"https://orcid.org/0000-0002-9453-8690","observed_orcids":["https://orcid.org/0000-0002-9453-8690","https://orcid.org/0009-0000-1263-2935"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Farzaneh Abbasi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9453-8690","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047831821","display_name":"Ali Tootee","orcid":"https://orcid.org/0000-0001-7629-2159","observed_orcids":["https://orcid.org/0000-0001-7629-2159"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ali Tootee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036199850","display_name":"Ramin Heshmat","orcid":"https://orcid.org/0000-0002-8134-7940","observed_orcids":["https://orcid.org/0000-0002-8134-7940","https://orcid.org/0000-0002-9498-6397"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ramin Heshmat","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8134-7940","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031147841","display_name":"Camelia Rambod","orcid":"https://orcid.org/0000-0003-1632-8265","observed_orcids":["https://orcid.org/0000-0003-1632-8265"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Camelia Rambod","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5007232361","display_name":"Bagher A. Larijani","orcid":"https://orcid.org/0000-0001-5386-7597","observed_orcids":["https://orcid.org/0000-0001-5386-7597"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bagher Larijani","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5386-7597","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2334,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.58018309,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":94},"biblio":{"volume":"44","issue":"2","first_page":"27","last_page":"35"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11171","display_name":"Diabetes and associated disorders","score":0.005799999926239252,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.996999979019165},{"id":"https://openalex.org/keywords/allogeneic-transplantation","display_name":"allogeneic transplantation","score":0.8880000114440918},{"id":"https://openalex.org/keywords/stem-cell-therapy","display_name":"stem cell therapy","score":0.7799999713897705},{"id":"https://openalex.org/keywords/insulin-independence","display_name":"insulin independence","score":0.9860000014305115},{"id":"https://openalex.org/keywords/c-peptide","display_name":"C-peptide","score":0.828000009059906},{"id":"https://openalex.org/keywords/hba1c","display_name":"HbA1c","score":0.9509999752044678},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.5950000286102295},{"id":"https://openalex.org/keywords/cell-therapy","display_name":"cell therapy","score":0.5680000185966492}],"concepts":[{"id":"https://openalex.org/C2777561873","wikidata":"https://www.wikidata.org/wiki/Q1773075","display_name":"Allotransplantation","level":3,"score":0.8248380422592163},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7801764607429504},{"id":"https://openalex.org/C2781232474","wikidata":"https://www.wikidata.org/wiki/Q124407","display_name":"Type 1 diabetes","level":3,"score":0.7571694850921631},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.6617147922515869},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6398085951805115},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.61481773853302},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.507302463054657},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.5057830810546875},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4895080327987671},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.4526885747909546},{"id":"https://openalex.org/C2779609443","wikidata":"https://www.wikidata.org/wiki/Q1368191","display_name":"Liver transplantation","level":3,"score":0.4292737543582916},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3945804536342621},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.35668930411338806},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.32987645268440247},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07460519671440125},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:doaj.org/article:10842c5347324cac927d23d3be157f91","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/10842c5347324cac927d23d3be157f91","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Iranian Journal of Public Health, Vol 44, Iss Supple 2 (2015)","raw_type":"article"},{"id":"mag:2181869417","doi":null,"is_oa":true,"landing_page_url":"https://ijph.tums.ac.ir/index.php/ijph/article/download/4912/4487","pdf_url":null,"source":{"id":"https://openalex.org/S4210187943","display_name":"Iranian Journal of Public Health","issn_l":"0304-4556","issn":["0304-4556","2251-6085","2251-6093"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319396","host_organization_name":"Knowledge E","host_organization_lineage":["https://openalex.org/P4310319396"],"host_organization_lineage_names":["Knowledge E"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Majallah-i bihda\u0304sht-i I\u0304ra\u0304n","raw_type":null}],"best_oa_location":{"id":"mag:2181869417","doi":null,"is_oa":true,"landing_page_url":"https://ijph.tums.ac.ir/index.php/ijph/article/download/4912/4487","pdf_url":null,"source":{"id":"https://openalex.org/S4210187943","display_name":"Iranian Journal of Public Health","issn_l":"0304-4556","issn":["0304-4556","2251-6085","2251-6093"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319396","host_organization_name":"Knowledge E","host_organization_lineage":["https://openalex.org/P4310319396"],"host_organization_lineage_names":["Knowledge E"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Majallah-i bihda\u0304sht-i I\u0304ra\u0304n","raw_type":null},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W49866007","https://openalex.org/W89330524","https://openalex.org/W1510928501","https://openalex.org/W1521943995","https://openalex.org/W1543468244","https://openalex.org/W1543916041","https://openalex.org/W1904143827","https://openalex.org/W1954306482","https://openalex.org/W1965404871","https://openalex.org/W1979828992","https://openalex.org/W1982948566","https://openalex.org/W1997470313","https://openalex.org/W2012219406","https://openalex.org/W2013453894","https://openalex.org/W2017071573","https://openalex.org/W2018321643","https://openalex.org/W2018896397","https://openalex.org/W2020736900","https://openalex.org/W2021967400","https://openalex.org/W2032157619","https://openalex.org/W2036232666","https://openalex.org/W2039233796","https://openalex.org/W2058118210","https://openalex.org/W2065228765","https://openalex.org/W2067875379","https://openalex.org/W2071379321","https://openalex.org/W2071734812","https://openalex.org/W2079205293","https://openalex.org/W2081468189","https://openalex.org/W2084544351","https://openalex.org/W2086655071","https://openalex.org/W2088113216","https://openalex.org/W2092410948","https://openalex.org/W2098742390","https://openalex.org/W2101399594","https://openalex.org/W2108881298","https://openalex.org/W2109565940","https://openalex.org/W2113589598","https://openalex.org/W2115936490","https://openalex.org/W2134303810","https://openalex.org/W2139607316","https://openalex.org/W2144036389","https://openalex.org/W2147402097","https://openalex.org/W2155621930","https://openalex.org/W2156193732","https://openalex.org/W2159079511","https://openalex.org/W2166582246","https://openalex.org/W2167304816","https://openalex.org/W2394534298","https://openalex.org/W2421543381"],"related_works":["https://openalex.org/W2993597609","https://openalex.org/W89330524","https://openalex.org/W2096213726","https://openalex.org/W2043989907","https://openalex.org/W2065228765","https://openalex.org/W7117841128","https://openalex.org/W4402843606","https://openalex.org/W2147402097","https://openalex.org/W2021899770","https://openalex.org/W2982936074"],"abstract_inverted_index":{"Background:":[0],"Cell-based":[1],"treatments":[2],"are":[3,186],"currently":[4],"being":[5],"actively":[6],"received":[7],"great":[8],"attention":[9],"among":[10],"scientists":[11],"and":[12,180,185],"clinicians":[13],"for":[14,101,167],"a":[15],"variety":[16],"of":[17,25,33,35,70,77,88,97,110,116,118,129,136,142,164,169,183,193],"diseases":[18],"as":[19,21,188,190],"well":[20,189],"diabetes":[22,51,130],".The":[23],"aim":[24],"this":[26,137],"study":[27,138],"was":[28,65],"to":[29,103],"investigate":[30],"the":[31,59,68,85,98],"effect":[32],"allotransplantation":[34],"fetal":[36,143],"liver-derived":[37,62],"cell":[38,63],"suspension":[39,64],"in":[40,58,93,127,155],"patients":[41,95,156,184],"with":[42,48,114,157,174],"type":[43,49,158],"1":[44,50,159,200],"diabetes.":[45,160],"Methods:":[46],"Patients":[47],"(n=16)":[52],"aged":[53],"6-30":[54],"years-old":[55],"were":[56,132],"included":[57],"study.":[60],"Fetal":[61,203],"transplanted":[66],"by":[67],"means":[69],"intravenous":[71],"injection":[72],"patient.":[73],"Results:":[74],"In":[75,121],"most":[76],"patient,":[78],"blood":[79],"glucose":[80],"levels":[81,109,117],"gradually":[82],"decreased":[83],"within":[84],"first":[86],"day":[87],"infusion.":[89],"Insulin":[90],"independence":[91],"occurred":[92],"3":[94],"out":[96],"16":[99],"(18.7%)":[100],"4":[102],"24":[104],"months.":[105],"They":[106],"showed":[107],"increasing":[108],"serum":[111],"c-peptide":[112],"along":[113],"decreasing":[115],"HbA1c":[119],"level.":[120],"other":[122],"patients,":[123],"no":[124],"significant":[125],"changes":[126],"parameters":[128],"control":[131],"observed.":[133],"Conclusion:":[134],"Findings":[135],"indicated":[139],"that":[140],"transplantation":[141],"stem":[144],"cells":[145],"could,":[146],"although":[147],"not":[148],"permanently,":[149],"be":[150],"an":[151],"effective":[152],"therapeutic":[153],"intervention":[154],"To":[161],"demonstrate":[162],"effectiveness":[163],"stem-cell":[165],"therapy":[166],"treatment":[168],"diabetes,":[170,201],"more":[171],"clinical":[172],"trials":[173],"stricter":[175],"inclusion":[176],"criteria,":[177],"modified":[178],"protocols,":[179],"larger":[181],"number":[182],"necessary":[187],"long":[191],"periods":[192],"follow":[194],"up.":[195],"Keywords:":[196],"Stem":[197],"cell,":[198],"Type":[199],"Allotransplantation,":[202],"Liver-Derived":[204],"Cell":[205,207],"Suspension,":[206],"Therapy":[208]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}