{"id":"https://openalex.org/W2181743959","doi":"https://doi.org/","title":"Expression of VLA1, VLA2 and VLA3 Integrin Molecules in Uterine Endometrium of Infertile Women with Unexplained Aetiology in Ahwaz-Iran.","display_name":"Expression of VLA1, VLA2 and VLA3 Integrin Molecules in Uterine Endometrium of Infertile Women with Unexplained Aetiology in Ahwaz-Iran.","publication_year":2006,"publication_date":"2006-12-01","ids":{"openalex":"https://openalex.org/W2181743959","doi":"https://doi.org/","mag":"2181743959","pmid":"https://pubmed.ncbi.nlm.nih.gov/18685175"},"language":"en","primary_location":{"id":"pmid:18685175","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18685175","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Iranian journal of immunology : IJI","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050707630","display_name":"Mehri Ghafourian","orcid":"https://orcid.org/0000-0003-0140-7083","observed_orcids":["https://orcid.org/0000-0003-0140-7083"]},"institutions":[{"id":"https://openalex.org/I119939603","display_name":"Ahvaz Jundishapur University of Medical Sciences","ror":"https://ror.org/01rws6r75","country_code":"IR","type":"education","lineage":["https://openalex.org/I119939603"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mehri Ghafourian Boroujerdnia","raw_affiliation_strings":["Department of Immunology, Medical College, Ahvaz Jondishapour University of Medical Sciences, Ahwaz Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Medical College, Ahvaz Jondishapour University of Medical Sciences, Ahwaz Iran","institution_ids":["https://openalex.org/I119939603"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029431931","display_name":"Fatemeh Ghalambor Dezfuly","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fatemeh Ghalambor Dezfuly","raw_affiliation_strings":["Department of Obstetrics and Gynaeocology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynaeocology","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091651237","display_name":"Nepton Emad Mosthophy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I119939603","display_name":"Ahvaz Jundishapur University of Medical Sciences","ror":"https://ror.org/01rws6r75","country_code":"IR","type":"education","lineage":["https://openalex.org/I119939603"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Nepton Emad Mosthophy","raw_affiliation_strings":["Department of Pathology,#N#Medical College, Ahvaz Jondishapour University of Medical Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology,#N#Medical College, Ahvaz Jondishapour University of Medical Sciences","institution_ids":["https://openalex.org/I119939603"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031309645","display_name":"Rahim Chinipardaz","orcid":"https://orcid.org/0000-0003-1058-4735","observed_orcids":["https://orcid.org/0000-0003-1058-4735"]},"institutions":[{"id":"https://openalex.org/I196051555","display_name":"Shahid Chamran University of Ahvaz","ror":"https://ror.org/01k3mbs15","country_code":"IR","type":"education","lineage":["https://openalex.org/I196051555"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Rahim Chinipardaz","raw_affiliation_strings":["Department of Statistics,#N#Shahid Chamran University, Ahwaz Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics,#N#Shahid Chamran University, Ahwaz Iran","institution_ids":["https://openalex.org/I196051555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.12,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.4654176,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"3","issue":"4","first_page":"157","last_page":"63"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.012900000438094139,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11156","display_name":"Reproductive Health and Technologies","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vla-1","display_name":"VLA-1","score":0.6970000267028809},{"id":"https://openalex.org/keywords/integrin-alpha2beta1","display_name":"alpha2beta1 integrin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/integrin-alpha3beta1","display_name":"alpha3beta1 integrin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/beta1-integrin","display_name":"beta1 integrin","score":0.8690000176429749},{"id":"https://openalex.org/keywords/endometrium","display_name":"endometrium","score":0.8640000224113464},{"id":"https://openalex.org/keywords/unexplained-infertility","display_name":"unexplained infertility","score":0.9929999709129333},{"id":"https://openalex.org/keywords/window-of-implantation","display_name":"implantation window","score":0.781000018119812},{"id":"https://openalex.org/keywords/endometrial-stroma","display_name":"endometrial stroma","score":0.7590000033378601},{"id":"https://openalex.org/keywords/endometrial-epithelium","display_name":"endometrial epithelium","score":0.9700000286102295},{"id":"https://openalex.org/keywords/endometrial-blood-vessels","display_name":"endometrial blood vessels","score":0.7279999852180481},{"id":"https://openalex.org/keywords/implantation","display_name":"implantation","score":0.4410000145435333},{"id":"https://openalex.org/keywords/placental-development","display_name":"placental development","score":0.8650000095367432}],"concepts":[{"id":"https://openalex.org/C2779742232","wikidata":"https://www.wikidata.org/wiki/Q839508","display_name":"Endometrium","level":2,"score":0.8231894969940186},{"id":"https://openalex.org/C2778580812","wikidata":"https://www.wikidata.org/wiki/Q686627","display_name":"Unexplained infertility","level":4,"score":0.6531556248664856},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.5995419025421143},{"id":"https://openalex.org/C16930146","wikidata":"https://www.wikidata.org/wiki/Q4381253","display_name":"Stromal cell","level":2,"score":0.5793759822845459},{"id":"https://openalex.org/C2777688143","wikidata":"https://www.wikidata.org/wiki/Q179399","display_name":"Infertility","level":3,"score":0.5705554485321045},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.542339026927948},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.465295672416687},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4197745621204376},{"id":"https://openalex.org/C2776606343","wikidata":"https://www.wikidata.org/wiki/Q5376361","display_name":"Endometrial biopsy","level":3,"score":0.41339969635009766},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.413386732339859},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4112284183502197},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.26085978746414185},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2173956036567688},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.1789490282535553},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.16116970777511597},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.05191585421562195}],"mesh":[],"locations_count":3,"locations":[{"id":"pmid:18685175","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18685175","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Iranian journal of immunology : IJI","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.578.4139","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.578.4139","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.iji.ir/autumn2006/2ndiji_vol3_no4_2006.pdf","raw_type":"text"},{"id":"mag:2181743959","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18685175","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W918767556","https://openalex.org/W1918962518","https://openalex.org/W1964764413","https://openalex.org/W1968771584","https://openalex.org/W1976957093","https://openalex.org/W1979968291","https://openalex.org/W1986680383","https://openalex.org/W1990389515","https://openalex.org/W1995909293","https://openalex.org/W2012075510","https://openalex.org/W2012532001","https://openalex.org/W2029231027","https://openalex.org/W2032296790","https://openalex.org/W2032621162","https://openalex.org/W2053402864","https://openalex.org/W2059015995","https://openalex.org/W2061164572","https://openalex.org/W2072078727","https://openalex.org/W2090598611","https://openalex.org/W2100592302","https://openalex.org/W2103385168","https://openalex.org/W2104956743","https://openalex.org/W2106725974","https://openalex.org/W2119256066","https://openalex.org/W2121605257","https://openalex.org/W2135898609","https://openalex.org/W2144032368","https://openalex.org/W2146778458","https://openalex.org/W2283899119","https://openalex.org/W2308174658","https://openalex.org/W2325674170","https://openalex.org/W2330920156","https://openalex.org/W2346080566","https://openalex.org/W2398137194","https://openalex.org/W2415505085","https://openalex.org/W2419677984"],"related_works":["https://openalex.org/W7100579739","https://openalex.org/W2308174658","https://openalex.org/W2756777307","https://openalex.org/W1568364584","https://openalex.org/W2057391118","https://openalex.org/W2059015995","https://openalex.org/W4292365867","https://openalex.org/W2001065131","https://openalex.org/W4230722976","https://openalex.org/W2097833103"],"abstract_inverted_index":{"BACKGROUND:":[0],"Recent":[1],"attention":[2],"has":[3],"focused":[4],"on":[5,115,162,191,213],"the":[6,12,29,38,47,110,151,172,201,206,211,235],"expression":[7,39,111,152,161,190],"of":[8,31,40,49,56,112,153,169,175,210,224,237],"integrin":[9,89],"molecules":[10,155,212],"within":[11,123],"endometrium,":[13],"and":[14,64,98,121,141,148,197,215,227,244],"their":[15],"relation":[16],"to":[17,26,93,108,205,241],"infertility.":[18],"OBJECTIVE:":[19],"The":[20,130],"present":[21,138],"prospective":[22],"study":[23],"was":[24,106],"undertaken":[25],"determine":[27],"whether":[28],"endometrium":[30,48,143],"women":[32,73,182],"with":[33,61,83,183],"unexplained":[34,198,225],"infertility":[35],"differs":[36],"in":[37,74,139,150,156,177,195,234],"very":[41],"late":[42],"activation":[43],"antigens":[44,114],"(VLA)":[45],"from":[46,59,71],"normal":[50],"fertile":[51,140,179,196],"women.":[52],"METHODS:":[53],"Thirty":[54],"samples":[55,67],"endometrial":[57,66,124,163,192],"biopsies":[58],"hysterectomies":[60],"nonendometrial":[62],"pathology":[63],"28":[65],"by":[68,95,102],"uterine":[69],"curetting":[70],"infertile":[72,142,181,199],"secretary":[75],"phase":[76],"at":[77],"implantation":[78,176,243],"time":[79],"were":[80,137,146,203],"collected,":[81],"stained":[82],"three":[84],"monoclonal":[85],"antibodies":[86],"against":[87],"beta1":[88],"subunits":[90],"including":[91],"VLA-1":[92,189],"VLA-3":[94,160],"immunohistochemical":[96],"technique":[97],"then":[99],"assessed":[100],"semiquantitively":[101],"microscope.":[103],"Chi-Square":[104],"test":[105],"used":[107],"compare":[109],"VLA":[113,135,154],"epithelial":[116,214],"cells,":[117,119],"stromal":[118,216],"lymphocytes":[120],"vessels":[122],"tissues":[125],"between":[126],"two":[127],"groups.":[128],"RESULTS:":[129],"results":[131],"showed":[132,165],"that":[133,229],"most":[134],"integrins":[136,231],"tissues.":[144],"There":[145],"similarities":[147],"differences":[149,186,202],"different":[157],"compartments.":[158],"VLA-2,":[159],"compartments":[164,193],"an":[166],"unaltered":[167],"pattern":[168],"staining":[170],"during":[171],"putative":[173],"window":[174],"either":[178],"or":[180,208],"no":[184],"significant":[185],"(P-value>":[187],"0.5).":[188],"changed":[194],"women,":[200],"related":[204],"presence":[207],"lack":[209],"cells":[217],"respectively.":[218],"CONCLUSION:":[219],"Differences":[220],"may":[221,232],"explain":[222],"causes":[223],"infertility,":[226],"suggests":[228],"certain":[230],"participate":[233],"cascade":[236],"molecular":[238],"events":[239],"leading":[240],"successful":[242],"early":[245],"placental":[246],"development":[247],"which":[248],"requires":[249],"more":[250],"investigations.":[251]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}