{"id":"https://openalex.org/W2181621086","doi":"https://doi.org/10.1109/biocas.2015.7348348","title":"Enabling closed-loop neurostimulation research with downloadable firmware upgrades","display_name":"Enabling closed-loop neurostimulation research with downloadable firmware upgrades","publication_year":2015,"publication_date":"2015-10-01","ids":{"openalex":"https://openalex.org/W2181621086","doi":"https://doi.org/10.1109/biocas.2015.7348348","mag":"2181621086"},"language":"en","primary_location":{"id":"doi:10.1109/biocas.2015.7348348","doi":"https://doi.org/10.1109/biocas.2015.7348348","is_oa":false,"landing_page_url":"https://doi.org/10.1109/biocas.2015.7348348","pdf_url":null,"source":{"id":"https://openalex.org/S4363608179","display_name":"IEEE Biomedical Circuits and Systems Conference (BioCAS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 IEEE Biomedical Circuits and Systems Conference (BioCAS)","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040551832","display_name":"Preeya Khanna","orcid":"https://orcid.org/0000-0001-6402-6486","observed_orcids":["https://orcid.org/0000-0001-6402-6486"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Preeya Khanna","raw_affiliation_strings":["UC Berkeley/UCSF Joint Graduate Group in Bioengineering"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UC Berkeley/UCSF Joint Graduate Group in Bioengineering","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028620917","display_name":"Scott R. Stanslaski","orcid":"https://orcid.org/0000-0002-3513-2391","observed_orcids":["https://orcid.org/0000-0002-3513-2391"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Scott Stanslaski","raw_affiliation_strings":["Neuromodulation Technology, PLC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuromodulation Technology, PLC","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063528444","display_name":"Yizi Xiao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yizi Xiao","raw_affiliation_strings":["Neuromodulation Technology, PLC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuromodulation Technology, PLC","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019887914","display_name":"Terry Ahrens","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Terry Ahrens","raw_affiliation_strings":["Neuromodulation Technology, PLC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuromodulation Technology, PLC","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066861022","display_name":"Duane Bourget","orcid":"https://orcid.org/0000-0003-0637-8875","observed_orcids":["https://orcid.org/0000-0003-0637-8875"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Duane Bourget","raw_affiliation_strings":["Neuromodulation Technology, PLC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuromodulation Technology, PLC","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059859995","display_name":"Nicole C. Swann","orcid":"https://orcid.org/0000-0003-2463-5134","observed_orcids":["https://orcid.org/0000-0003-2463-5134"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicole Swann","raw_affiliation_strings":["Department of Neurological Surgery, University of California, San Francisco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurological Surgery, University of California, San Francisco","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024860464","display_name":"Philip A. Starr","orcid":"https://orcid.org/0000-0003-2733-4003","observed_orcids":["https://orcid.org/0000-0003-2733-4003"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Philip Starr","raw_affiliation_strings":["Department of Neurological Surgery, University of California, San Francisco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurological Surgery, University of California, San Francisco","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024864142","display_name":"Jose M. Carmena","orcid":"https://orcid.org/0000-0002-0214-2489","observed_orcids":["https://orcid.org/0000-0002-0214-2489"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jose M. Carmena","raw_affiliation_strings":["University of California Berkeley, Berkeley, CA, US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Berkeley, Berkeley, CA, US","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031652451","display_name":"Timothy Denison","orcid":"https://orcid.org/0000-0002-5404-4004","observed_orcids":["https://orcid.org/0000-0002-5404-4004"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Timothy Denison","raw_affiliation_strings":["Neuromodulation Technology, PLC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuromodulation Technology, PLC","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":14.0993,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.98765432,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12580","display_name":"Vagus Nerve Stimulation Research","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/closed-loop-neurostimulation","display_name":"closed-loop neurostimulation","score":0.9739999771118164},{"id":"https://openalex.org/keywords/deep-brain-stimulation","display_name":"deep brain stimulation","score":0.9440000057220459},{"id":"https://openalex.org/keywords/movement-disorders","display_name":"movement disorders","score":0.8629999756813049},{"id":"https://openalex.org/keywords/depth-electrodes","display_name":"depth electrodes","score":0.9369999766349792},{"id":"https://openalex.org/keywords/stimulation-timing","display_name":"stimulation timing","score":0.46700000762939453}],"concepts":[{"id":"https://openalex.org/C67212190","wikidata":"https://www.wikidata.org/wiki/Q104851","display_name":"Firmware","level":2,"score":0.9526760578155518},{"id":"https://openalex.org/C2776443511","wikidata":"https://www.wikidata.org/wiki/Q1724687","display_name":"Neurostimulation","level":3,"score":0.836286187171936},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7147424221038818},{"id":"https://openalex.org/C2780615140","wikidata":"https://www.wikidata.org/wiki/Q920419","display_name":"Upgrade","level":2,"score":0.6836861968040466},{"id":"https://openalex.org/C3019251811","wikidata":"https://www.wikidata.org/wiki/Q5135346","display_name":"Closed loop","level":2,"score":0.5148152709007263},{"id":"https://openalex.org/C2780008327","wikidata":"https://www.wikidata.org/wiki/Q3962","display_name":"Laptop","level":2,"score":0.41016319394111633},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.40217679738998413},{"id":"https://openalex.org/C107457646","wikidata":"https://www.wikidata.org/wiki/Q207434","display_name":"Human\u2013computer interaction","level":1,"score":0.3688775897026062},{"id":"https://openalex.org/C9390403","wikidata":"https://www.wikidata.org/wiki/Q3966","display_name":"Computer hardware","level":1,"score":0.2679787278175354},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.24183771014213562},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.2235375940799713},{"id":"https://openalex.org/C133731056","wikidata":"https://www.wikidata.org/wiki/Q4917288","display_name":"Control engineering","level":1,"score":0.22039192914962769},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.1765185296535492},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.1742047667503357},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/biocas.2015.7348348","doi":"https://doi.org/10.1109/biocas.2015.7348348","is_oa":false,"landing_page_url":"https://doi.org/10.1109/biocas.2015.7348348","pdf_url":null,"source":{"id":"https://openalex.org/S4363608179","display_name":"IEEE Biomedical Circuits and Systems Conference (BioCAS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 IEEE Biomedical Circuits and Systems Conference (BioCAS)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4043000042438507}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332180","display_name":"Defense Advanced Research Projects Agency","ror":"https://ror.org/02caytj08"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1557627195","https://openalex.org/W1967168287","https://openalex.org/W1967428268","https://openalex.org/W1972879677","https://openalex.org/W1978232368","https://openalex.org/W1982475930","https://openalex.org/W2011861646","https://openalex.org/W2018175367","https://openalex.org/W2044719021","https://openalex.org/W2048272660","https://openalex.org/W2090475450","https://openalex.org/W2096948332","https://openalex.org/W2103908673","https://openalex.org/W2111420672","https://openalex.org/W2123196121","https://openalex.org/W2133947591","https://openalex.org/W2142123782","https://openalex.org/W2142280324","https://openalex.org/W2143685192"],"related_works":["https://openalex.org/W2183934724","https://openalex.org/W4391748984","https://openalex.org/W2906088800","https://openalex.org/W4200545287","https://openalex.org/W7097218818","https://openalex.org/W2974257491","https://openalex.org/W2088557382","https://openalex.org/W1557627195","https://openalex.org/W2023482529","https://openalex.org/W7034445693"],"abstract_inverted_index":{"We":[0],"present":[1],"a":[2,65,83],"simulated":[3],"case":[4,72,86],"study":[5,73],"using":[6,128],"investigational,":[7],"downloadable":[8],"firmware":[9],"updates":[10],"to":[11,38,63,80,97],"configure":[12],"an":[13],"existing":[14],"implanted":[15],"deep":[16],"brain":[17],"stimulator.":[18],"With":[19],"the":[20,36,93,103,109],"upgrade,":[21],"closed-loop":[22,44,68],"algorithm":[23],"parameters":[24],"affecting":[25],"stimulation":[26,30],"state":[27],"classification":[28],"and":[29,48,119,123,131],"timing":[31],"can":[32,52],"be":[33,53],"embedded":[34],"within":[35],"device":[37],"allow":[39],"for":[40,87],"chronic":[41,117],"investigation":[42],"of":[43,67,89,106,113,121],"concepts":[45],"both":[46],"flexibly":[47],"incrementally.":[49],"The":[50,70],"system":[51],"outfitted":[54],"with":[55],"either":[56],"cortical":[57],"sensing":[58],"electrodes":[59,62],"or":[60],"depth":[61],"explore":[64],"variety":[66],"paradigms.":[69],"prototype":[71],"presented":[74],"here":[75],"uses":[76],"motor":[77],"intention":[78],"signals":[79],"titrate":[81],"stimulation,":[82],"relevant":[84],"use":[85],"treatment":[88],"movement":[90],"disorders,":[91],"though":[92],"technology":[94,111],"is":[95],"extensible":[96],"other":[98],"neurological":[99],"disorders.":[100],"To":[101],"highlight":[102],"translational":[104],"capabilities":[105],"this":[107],"tool,":[108],"key":[110],"considerations":[112],"battery":[114],"power":[115],"usage,":[116],"sensitivity":[118],"stability":[120],"biomarkers,":[122],"parameter":[124],"tuning":[125],"are":[126],"discussed":[127],"representative":[129],"testing":[130],"data":[132],"sources.":[133]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":2}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}