{"id":"https://openalex.org/W2181509963","doi":null,"title":"ASSESSMENT OF ANTIDIABETIC ACTIVITY OF ETHANOL EXTRACTS OF PHYLLANTHUS ACIDUS LINN AND BASELLA RUBRA LINN LEAVES AGAINST STREPTOZOTOCIN INDUCED DIABETES IN RATS","display_name":"ASSESSMENT OF ANTIDIABETIC ACTIVITY OF ETHANOL EXTRACTS OF PHYLLANTHUS ACIDUS LINN AND BASELLA RUBRA LINN LEAVES AGAINST STREPTOZOTOCIN INDUCED DIABETES IN RATS","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W2181509963","mag":"2181509963"},"language":"en","primary_location":{"id":"mag:2181509963","doi":null,"is_oa":false,"landing_page_url":"http://ijupbs.com/uploads/10.assessment of antidiabetic activity of ethanol extracts of phyllanthus acidus.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"S. D. Mohana","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. D. Mohana","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045811813","display_name":"Y. Sudhakar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y. Sudhakar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000559007","display_name":"Kale Ravindra","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kale Ravindra","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035255074","display_name":"P. Rami","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. Rami","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5057286719","display_name":"Reddy Memorial","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Reddy Memorial","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2059,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.61827885,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13719","display_name":"Phytochemistry and Bioactivity Studies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phyllanthus-acidus","display_name":"Phyllanthus acidus","score":0.9319999814033508},{"id":"https://openalex.org/keywords/basella-rubra","display_name":"Basella rubra","score":0.9990000128746033},{"id":"https://openalex.org/keywords/antidiabetic-activity","display_name":"antidiabetic activity","score":0.9929999709129333},{"id":"https://openalex.org/keywords/streptozotocin-induced-diabetes","display_name":"streptozotocin-induced diabetes","score":0.9760000109672546},{"id":"https://openalex.org/keywords/ethanolic-leaf-extract","display_name":"ethanolic leaf extract","score":0.8840000033378601},{"id":"https://openalex.org/keywords/blood-glucose","display_name":"blood glucose","score":0.6819999814033508},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.9300000071525574},{"id":"https://openalex.org/keywords/liver-enzymes","display_name":"liver enzymes","score":0.7789999842643738},{"id":"https://openalex.org/keywords/glycogen-content","display_name":"glycogen content","score":0.6880000233650208},{"id":"https://openalex.org/keywords/glibenclamide","display_name":"glibenclamide","score":0.753000020980835},{"id":"https://openalex.org/keywords/phytochemical-screening","display_name":"phytochemical screening","score":0.753000020980835},{"id":"https://openalex.org/keywords/acute-toxicity","display_name":"acute toxicity","score":0.6729999780654907},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.7850000262260437}],"concepts":[{"id":"https://openalex.org/C2779768347","wikidata":"https://www.wikidata.org/wiki/Q420626","display_name":"Glibenclamide","level":3,"score":0.8250142335891724},{"id":"https://openalex.org/C2779280383","wikidata":"https://www.wikidata.org/wiki/Q257331","display_name":"Streptozotocin","level":3,"score":0.7910432815551758},{"id":"https://openalex.org/C195475562","wikidata":"https://www.wikidata.org/wiki/Q1639139","display_name":"Phytochemical","level":2,"score":0.7508665323257446},{"id":"https://openalex.org/C2777499176","wikidata":"https://www.wikidata.org/wiki/Q174936","display_name":"Glycogen","level":2,"score":0.6785609722137451},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.6656472682952881},{"id":"https://openalex.org/C2776718122","wikidata":"https://www.wikidata.org/wiki/Q310927","display_name":"Phyllanthus","level":2,"score":0.5975149869918823},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5919337868690491},{"id":"https://openalex.org/C2780161600","wikidata":"https://www.wikidata.org/wiki/Q153","display_name":"Ethanol","level":2,"score":0.5081543922424316},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5008988380432129},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3840479850769043},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.26003313064575195},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21289944648742676},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.15168511867523193}],"mesh":[],"locations_count":2,"locations":[{"id":"mag:2181509963","doi":null,"is_oa":false,"landing_page_url":"http://ijupbs.com/uploads/10.assessment of antidiabetic activity of ethanol extracts of phyllanthus acidus.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"mag:3143755831","doi":null,"is_oa":false,"landing_page_url":"http://www.ijupbs.com/Uploads/10.Assessment%20of%20antidiabetic%20activity%20of%20ethanol%20extracts%20of%20Phyllanthus%20acidus.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W196476257","https://openalex.org/W1993406529","https://openalex.org/W2000097797","https://openalex.org/W2000730364","https://openalex.org/W2028545626","https://openalex.org/W2045453026","https://openalex.org/W2083640428","https://openalex.org/W2086999040","https://openalex.org/W2094098664","https://openalex.org/W2098548547","https://openalex.org/W2140821051","https://openalex.org/W2153631564","https://openalex.org/W2184575622","https://openalex.org/W2263023695","https://openalex.org/W2460921557"],"related_works":["https://openalex.org/W3140564259","https://openalex.org/W4380885350","https://openalex.org/W4302375398","https://openalex.org/W4313474305","https://openalex.org/W2331794420","https://openalex.org/W7218954061","https://openalex.org/W7156337559","https://openalex.org/W3203799096","https://openalex.org/W2538052992","https://openalex.org/W2003985316"],"abstract_inverted_index":{"The":[0,26,96,181],"antidiabetic":[1],"potentials":[2,72],"of":[3,6,46,53,73,104,131,148,168,202],"ethanol":[4],"extracts":[5,59,147],"Phyllanthus":[7],"acidus":[8],"Linn":[9,15],"(Phyllanthaceae)":[10],"(EEPA)":[11],"and":[12,41,50,75,81,108,120,128,138,163,171,186,189],"Basella":[13],"rubra":[14],"(Basellaceae)":[16],"(EEBR)":[17],"were":[18,30,85,99,122],"investigated":[19],"against":[20],"streptozotocin":[21,88],"induced":[22,90],"diabetes":[23],"in":[24,135,155,177],"rats.":[25],"shade":[27],"dried":[28],"leaves":[29],"extracted":[31],"by":[32],"soxhlation":[33],"using":[34],"ethanol.":[35],"Phytochemical":[36],"studies":[37],"showed":[38,151],"that":[39,58,184],"EEPA":[40,74,185],"EEBR":[42,76,187],"contain":[43],"significant":[44,152],"quantities":[45],"Flavanoids,":[47],"Tannins,":[48],"Triterpenoids":[49],"Phytosterols.":[51],"Results":[52],"acute":[54],"toxicity":[55],"study":[56],"suggested":[57,183],"can":[60],"be":[61],"considered":[62],"as":[63,66],"category":[64],"5":[65],"per":[67],"OECD":[68],"guidelines":[69],"425.":[70],"Antidiabetic":[71],"at":[77,124,200],"doses":[78],"100,":[79],"200":[80],"400":[82,203],"mg/kg":[83],"b.wt.":[84],"studied":[86],"on":[87],"(STZ)":[89],"diabetic":[91,106],"rats":[92],"for":[93],"21":[94,129,144],"days.":[95,145],"obtained":[97],"results":[98,103,182],"compared":[100],"with":[101,196],"the":[102,136],"control,":[105],"control":[107],"standard":[109],"(Glibenclamide)":[110],"groups.":[111],"Blood":[112],"glucose":[113,157],"levels,":[114,158],",":[115],"Lipid":[116,159],"profile,":[117],"SGOT,":[118,161],"SGPT":[119,162],"ALP":[121],"analyzed":[123],"0,":[125],"7,":[126],"14":[127],"days":[130],"study.":[132],"Glycogen":[133],"content":[134],"liver":[137,170],"skeletal":[139],"muscle":[140,172],"was":[141,175],"estimated":[142],"after":[143],"Ethanol":[146],"selected":[149],"plants":[150],"reduction":[153],"(**P<0.01)":[154],"blood":[156],"level,":[160],"ALP.":[164],"In":[165],"contrast,":[166],"elevation":[167],"HDLC,":[169],"glycogen":[173],"levels":[174],"observed":[176],"dose":[178,201],"dependent":[179],"manner.":[180],"(96.13%":[188],"93.6%)":[190],"are":[191],"having":[192],"equipotent":[193],"effect":[194],"compare":[195],"Glibenclamide":[197],"(97.8":[198],"%)":[199],"mg/kg.":[204]},"counts_by_year":[{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}