{"id":"https://openalex.org/W2180839999","doi":"https://doi.org/10.1667/0033-7587(2000)153[0454:sbibpi]2.0.co;2","title":"Strand Break Induction by Photoabsorption in DNA-Bound Molecules","display_name":"Strand Break Induction by Photoabsorption in DNA-Bound Molecules","publication_year":2000,"publication_date":"2000-04-01","ids":{"openalex":"https://openalex.org/W2180839999","doi":"https://doi.org/10.1667/0033-7587(2000)153[0454:sbibpi]2.0.co;2","mag":"2180839999","pmid":"https://pubmed.ncbi.nlm.nih.gov/10761007"},"language":"en","primary_location":{"id":"doi:10.1667/0033-7587(2000)153[0454:sbibpi]2.0.co;2","doi":"https://doi.org/10.1667/0033-7587(2000)153[0454:sbibpi]2.0.co;2","is_oa":false,"landing_page_url":"https://doi.org/10.1667/0033-7587(2000)153[0454:sbibpi]2.0.co;2","pdf_url":null,"source":{"id":"https://openalex.org/S152208300","display_name":"Radiation Research","issn_l":"0033-7587","issn":["0033-7587","1938-5404"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315745","host_organization_name":"Radiation Research Society","host_organization_lineage":["https://openalex.org/P4310315745"],"host_organization_lineage_names":["Radiation Research Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiation Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040575773","display_name":"Claude Le Sech","orcid":"https://orcid.org/0000-0001-8710-1311","observed_orcids":["https://orcid.org/0000-0001-8710-1311"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"C. Le Sech","raw_affiliation_strings":["Laboratoire des Collisions Atomiques et Mol\u00e9culaires (URA 281) B\u00e2t 351, 91405 Orsay Cedex, France","aLaboratoire des Collisions Atomiques et Mol\u00e9culaires (URA 281) B\u00e2t 351, 91405 Orsay Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire des Collisions Atomiques et Mol\u00e9culaires (URA 281) B\u00e2t 351, 91405 Orsay Cedex, France","institution_ids":[]},{"raw_affiliation_string":"aLaboratoire des Collisions Atomiques et Mol\u00e9culaires (URA 281) B\u00e2t 351, 91405 Orsay Cedex, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059153431","display_name":"Kaoru Takakura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I199080787","display_name":"International Christian University","ror":"https://ror.org/01cg0k189","country_code":"JP","type":"education","lineage":["https://openalex.org/I199080787"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K. Takakura","raw_affiliation_strings":["bDepartment of Physics, College of Liberal Arts, International Christian University, Mitaka-shi, Osa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"bDepartment of Physics, College of Liberal Arts, International Christian University, Mitaka-shi, Osa","institution_ids":["https://openalex.org/I199080787"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008557150","display_name":"Christelle Saint\u2010Marc","orcid":"https://orcid.org/0000-0001-9537-1848","observed_orcids":["https://orcid.org/0000-0001-9537-1848"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210118525","display_name":"Centre de Biophysique Mol\u00e9culaire","ror":"https://ror.org/02dpqcy73","country_code":"FR","type":"facility","lineage":["https://openalex.org/I110017253","https://openalex.org/I12449238","https://openalex.org/I1294671590","https://openalex.org/I4210096427","https://openalex.org/I4210118525","https://openalex.org/I4210128300"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C. Saint-Marc","raw_affiliation_strings":["cCentre de Biophysique Mol\u00e9culaire, CNRS, rue Charles-Sadron, 45071 Orl\u00e9ans Cedex 2, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"cCentre de Biophysique Mol\u00e9culaire, CNRS, rue Charles-Sadron, 45071 Orl\u00e9ans Cedex 2, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210118525"]}]},{"author_position":"middle","author":{"id":null,"display_name":"H. Frohlich","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H. Frohlich","raw_affiliation_strings":["aLaboratoire des Collisions Atomiques et Mol\u00e9culaires (URA 281) B\u00e2t 351, 91405 Orsay Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"aLaboratoire des Collisions Atomiques et Mol\u00e9culaires (URA 281) B\u00e2t 351, 91405 Orsay Cedex, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007821857","display_name":"Michel Charlier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210118525","display_name":"Centre de Biophysique Mol\u00e9culaire","ror":"https://ror.org/02dpqcy73","country_code":"FR","type":"facility","lineage":["https://openalex.org/I110017253","https://openalex.org/I12449238","https://openalex.org/I1294671590","https://openalex.org/I4210096427","https://openalex.org/I4210118525","https://openalex.org/I4210128300"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"M. Charlier","raw_affiliation_strings":["cCentre de Biophysique Mol\u00e9culaire, CNRS, rue Charles-Sadron, 45071 Orl\u00e9ans Cedex 2, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"cCentre de Biophysique Mol\u00e9culaire, CNRS, rue Charles-Sadron, 45071 Orl\u00e9ans Cedex 2, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210118525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044984765","display_name":"Noriko Usami","orcid":"https://orcid.org/0000-0002-6157-8418","observed_orcids":["https://orcid.org/0000-0002-6157-8418"]},"institutions":[{"id":"https://openalex.org/I138728355","display_name":"High Energy Accelerator Research Organization","ror":"https://ror.org/01g5y5k24","country_code":"JP","type":"facility","lineage":["https://openalex.org/I1319490839","https://openalex.org/I138728355"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"N. Usami","raw_affiliation_strings":["dPhoton Factory, National Laboratory for High Energy Physics, Oho, Tsukuba, Ibaraki 305, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"dPhoton Factory, National Laboratory for High Energy Physics, Oho, Tsukuba, Ibaraki 305, Japan","institution_ids":["https://openalex.org/I138728355"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100763633","display_name":"Kazuo Kobayashi","orcid":"https://orcid.org/0000-0002-5586-9112","observed_orcids":["https://orcid.org/0000-0002-5586-9112"]},"institutions":[{"id":"https://openalex.org/I138728355","display_name":"High Energy Accelerator Research Organization","ror":"https://ror.org/01g5y5k24","country_code":"JP","type":"facility","lineage":["https://openalex.org/I1319490839","https://openalex.org/I138728355"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K. Kobayashi","raw_affiliation_strings":["dPhoton Factory, National Laboratory for High Energy Physics, Oho, Tsukuba, Ibaraki 305, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"dPhoton Factory, National Laboratory for High Energy Physics, Oho, Tsukuba, Ibaraki 305, Japan","institution_ids":["https://openalex.org/I138728355"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5040575773"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0398,"has_fulltext":false,"cited_by_count":44,"citation_normalized_percentile":{"value":0.77640156,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"153","issue":"4","first_page":"454","last_page":"458"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10163","display_name":"Metal complexes synthesis and properties","score":0.6425999999046326,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10163","display_name":"Metal complexes synthesis and properties","score":0.6425999999046326,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.06620000302791595,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.053599998354911804,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-strand-breaks","display_name":"DNA strand breaks","score":0.9079999923706055},{"id":"https://openalex.org/keywords/photoabsorption","display_name":"photon absorption","score":0.8059999942779541},{"id":"https://openalex.org/keywords/auger-decay","display_name":"Auger decay","score":0.7429999709129333},{"id":"https://openalex.org/keywords/platinum-complexes","display_name":"platinum complexes","score":0.609000027179718},{"id":"https://openalex.org/keywords/single-strand-breaks","display_name":"single-strand breaks","score":0.8809999823570251},{"id":"https://openalex.org/keywords/dna-double-strand-breaks","display_name":"DNA double-strand breaks","score":1.0},{"id":"https://openalex.org/keywords/quantum-yield","display_name":"quantum yield","score":0.7590000033378601}],"concepts":[{"id":"https://openalex.org/C139210041","wikidata":"https://www.wikidata.org/wiki/Q2145840","display_name":"Resonance (particle physics)","level":2,"score":0.7541577816009521},{"id":"https://openalex.org/C111337013","wikidata":"https://www.wikidata.org/wiki/Q2737837","display_name":"Irradiation","level":2,"score":0.5829534530639648},{"id":"https://openalex.org/C518104683","wikidata":"https://www.wikidata.org/wiki/Q880","display_name":"Platinum","level":3,"score":0.526390790939331},{"id":"https://openalex.org/C58312451","wikidata":"https://www.wikidata.org/wiki/Q4817200","display_name":"Atom (system on chip)","level":2,"score":0.4950057864189148},{"id":"https://openalex.org/C184779094","wikidata":"https://www.wikidata.org/wiki/Q26383","display_name":"Atomic physics","level":1,"score":0.49277976155281067},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.47099751234054565},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.45708346366882324},{"id":"https://openalex.org/C171627272","wikidata":"https://www.wikidata.org/wiki/Q719512","display_name":"Auger effect","level":3,"score":0.42992785573005676},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.4182165265083313},{"id":"https://openalex.org/C2780646311","wikidata":"https://www.wikidata.org/wiki/Q1142501","display_name":"Auger","level":2,"score":0.327009379863739},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.23896360397338867},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.0},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004583","descriptor_name":"Electrons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014965","descriptor_name":"X-Rays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1667/0033-7587(2000)153[0454:sbibpi]2.0.co;2","doi":"https://doi.org/10.1667/0033-7587(2000)153[0454:sbibpi]2.0.co;2","is_oa":false,"landing_page_url":"https://doi.org/10.1667/0033-7587(2000)153[0454:sbibpi]2.0.co;2","pdf_url":null,"source":{"id":"https://openalex.org/S152208300","display_name":"Radiation Research","issn_l":"0033-7587","issn":["0033-7587","1938-5404"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315745","host_organization_name":"Radiation Research Society","host_organization_lineage":["https://openalex.org/P4310315745"],"host_organization_lineage_names":["Radiation Research Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiation Research","raw_type":"journal-article"},{"id":"pmid:10761007","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10761007","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiation research","raw_type":"Journal Article"},{"id":"pmh:10.1667/0033-7587(2000)153[0454:SBIBPI]2.0.CO;2","doi":null,"is_oa":false,"landing_page_url":"http://www.bioone.org/doi/10.1667/0033-7587%282000%29153%5B0454%3ASBIBPI%5D2.0.CO%3B2","pdf_url":null,"source":{"id":"https://openalex.org/S4306402358","display_name":"BioOne Complete (BioOne)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210111627","host_organization_name":"BioOne","host_organization_lineage":["https://openalex.org/I4210111627"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309749","display_name":"Association pour la Recherche sur le Cancer","ror":"https://ror.org/0489qz649"},{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"},{"id":"https://openalex.org/F4320329301","display_name":"Electricit\u00e9 de France","ror":null},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1641583379","https://openalex.org/W1996929717","https://openalex.org/W2000063927","https://openalex.org/W2015825745","https://openalex.org/W2039558739","https://openalex.org/W2093500137","https://openalex.org/W2098944515","https://openalex.org/W2140803105","https://openalex.org/W2144634347","https://openalex.org/W2152370778","https://openalex.org/W2318605963","https://openalex.org/W2319264492"],"related_works":["https://openalex.org/W2061341582","https://openalex.org/W2072160831","https://openalex.org/W2056627466","https://openalex.org/W424784776","https://openalex.org/W2127710383","https://openalex.org/W1995384238","https://openalex.org/W2319264492","https://openalex.org/W3163156265","https://openalex.org/W2978272163","https://openalex.org/W2140803105"],"abstract_inverted_index":{"Le":[0],"Sech,":[1],"C.,":[2,6],"Takakura,":[3],"K.,":[4],"Saint-Marc,":[5],"Frohlich,":[7],"H.,":[8],"Charlier,":[9],"M.,":[10],"Usami,":[11],"N.":[12],"and":[13,54,58,77,104,124],"Kobayashi,":[14],"K.":[15],"Strand":[16],"Break":[17],"Induction":[18],"by":[19,61,71,133],"Photoabsorption":[20],"in":[21,65],"DNA-Bound":[22],"Molecules.Dried":[23],"samples":[24],"of":[25,41,46,52,74,85,90,111],"a":[26],"DNA\u2013chloroterpyridine":[27],"platinum":[28,48,92],"complex":[29],"were":[30,96,115],"irradiated":[31],"with":[32],"monochromatic":[33],"X":[34],"rays":[35],"tuned":[36,97],"to":[37,118,139],"the":[38,42,47,62,72,82,86,91,99,112,122,127],"photoabsorption":[39],"resonance":[40,100,113],"LIII":[43,87],"inner":[44],"shell":[45],"atom.":[49],"The":[50,108,129],"number":[51],"single-":[53],"double-strand":[55],"breaks":[56],"(SSBs":[57],"DSBs)":[59],"triggered":[60],"Auger":[63],"effect":[64],"supercoiled":[66],"DNA":[67],"plasmids":[68],"was":[69],"measured":[70],"production":[73],"circular":[75],"nicked":[76],"linear":[78],"forms.":[79],"To":[80],"probe":[81],"specific":[83],"contribution":[84],"inner-shell":[88],"excitation":[89],"atom,":[93],"photon":[94],"wavelengths":[95],"on":[98],"energy":[101],"(on":[102],"peak)":[103],"below":[105],"(off":[106],"peak).":[107],"quantum":[109],"yields":[110],"radiation":[114],"typically":[116],"found":[117],"be":[119],"11":[120],"for":[121,126],"SSBs":[123],"1":[125],"DSBs.":[128],"DSB-to-SSB":[130],"ratio":[131],"increased":[132],"20%":[134],"when":[135],"switching":[136],"from":[137],"off-resonance":[138],"on-resonance":[140],"irradiation.":[141]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}