{"id":"https://openalex.org/W2180725693","doi":"https://doi.org/10.1128/iai.00918-15","title":"Helicobacter pylori Adaptation In Vivo in Response to a High-Salt Diet","display_name":"Helicobacter pylori Adaptation In Vivo in Response to a High-Salt Diet","publication_year":2015,"publication_date":"2015-10-05","ids":{"openalex":"https://openalex.org/W2180725693","doi":"https://doi.org/10.1128/iai.00918-15","mag":"2180725693","pmid":"https://pubmed.ncbi.nlm.nih.gov/26438795","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4645402"},"language":"en","primary_location":{"id":"doi:10.1128/iai.00918-15","doi":"https://doi.org/10.1128/iai.00918-15","is_oa":false,"landing_page_url":"https://doi.org/10.1128/iai.00918-15","pdf_url":null,"source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4645402","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103385971","display_name":"John T. Loh","orcid":"https://orcid.org/0000-0001-6497-7652","observed_orcids":["https://orcid.org/0000-0001-6497-7652"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John T. Loh","raw_affiliation_strings":["Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045112731","display_name":"Jennifer Angeline Gaddy","orcid":"https://orcid.org/0000-0002-2192-4224","observed_orcids":["https://orcid.org/0000-0002-2192-4224"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4210101790","display_name":"VA Tennessee Valley Healthcare System","ror":"https://ror.org/01c9rqr26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210101790","https://openalex.org/I4210112672"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer A. Gaddy","raw_affiliation_strings":["Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]},{"raw_affiliation_string":"Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I4210101790"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061544889","display_name":"Holly M. Scott Algood","orcid":"https://orcid.org/0000-0003-3735-4649","observed_orcids":["https://orcid.org/0000-0003-3735-4649"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4210101790","display_name":"VA Tennessee Valley Healthcare System","ror":"https://ror.org/01c9rqr26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210101790","https://openalex.org/I4210112672"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Holly M. Scott Algood","raw_affiliation_strings":["Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]},{"raw_affiliation_string":"Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I4210101790"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080161419","display_name":"Silvana Gaudieri","orcid":"https://orcid.org/0000-0001-6873-0198","observed_orcids":["https://orcid.org/0000-0001-6873-0198"]},"institutions":[{"id":"https://openalex.org/I176790772","display_name":"Murdoch University","ror":"https://ror.org/00r4sry34","country_code":"AU","type":"education","lineage":["https://openalex.org/I176790772"]},{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]},{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["AU","US"],"is_corresponding":false,"raw_author_name":"Silvana Gaudieri","raw_affiliation_strings":["Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia","School of Anatomy, Physiology, and Human Biology, University of Western Australia, Nedlands, Western Australia, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]},{"raw_affiliation_string":"Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia","institution_ids":["https://openalex.org/I176790772"]},{"raw_affiliation_string":"School of Anatomy, Physiology, and Human Biology, University of Western Australia, Nedlands, Western Australia, Australia","institution_ids":["https://openalex.org/I177877127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070165631","display_name":"Simon Alexander Mallal","orcid":"https://orcid.org/0000-0002-7036-1309","observed_orcids":["https://orcid.org/0000-0002-7036-1309"]},"institutions":[{"id":"https://openalex.org/I176790772","display_name":"Murdoch University","ror":"https://ror.org/00r4sry34","country_code":"AU","type":"education","lineage":["https://openalex.org/I176790772"]},{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["AU","US"],"is_corresponding":false,"raw_author_name":"Simon Mallal","raw_affiliation_strings":["Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]},{"raw_affiliation_string":"Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia","institution_ids":["https://openalex.org/I176790772"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017198868","display_name":"Timothy L. Cover","orcid":"https://orcid.org/0000-0001-8503-002X","observed_orcids":["https://orcid.org/0000-0001-8503-002X"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4210101790","display_name":"VA Tennessee Valley Healthcare System","ror":"https://ror.org/01c9rqr26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210101790","https://openalex.org/I4210112672"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy L. Cover","raw_affiliation_strings":["Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, USA"],"raw_orcid":"https://orcid.org/0000-0001-8503-002X","affiliations":[{"raw_affiliation_string":"Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]},{"raw_affiliation_string":"Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I4210101790"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.3407,"has_fulltext":true,"cited_by_count":28,"citation_normalized_percentile":{"value":0.91588916,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"83","issue":"12","first_page":"4871","last_page":"4883"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/helicobacter-pylori","display_name":"Helicobacter pylori","score":1.0},{"id":"https://openalex.org/keywords/high-salt-diet","display_name":"high-salt diet","score":0.9909999966621399},{"id":"https://openalex.org/keywords/intraspecies-genetic-diversity","display_name":"intraspecies genetic diversity","score":0.9330000281333923},{"id":"https://openalex.org/keywords/fur-gene","display_name":"fur gene","score":0.46399998664855957},{"id":"https://openalex.org/keywords/iron-acquisition","display_name":"iron acquisition","score":0.9399999976158142},{"id":"https://openalex.org/keywords/oxidative-stress-tolerance","display_name":"oxidative stress resistance","score":0.9950000047683716},{"id":"https://openalex.org/keywords/gastritis","display_name":"gastritis","score":0.4350000023841858},{"id":"https://openalex.org/keywords/sodium-chloride","display_name":"sodium chloride","score":0.39500001072883606},{"id":"https://openalex.org/keywords/host-adaptation","display_name":"host adaptation","score":0.41600000858306885},{"id":"https://openalex.org/keywords/mongolian-gerbil-model","display_name":"Mongolian gerbil model","score":0.8199999928474426},{"id":"https://openalex.org/keywords/gastric-adenocarcinoma-risk","display_name":"gastric adenocarcinoma risk","score":0.7829999923706055},{"id":"https://openalex.org/keywords/nonsynonymous-mutations","display_name":"non-synonymous mutations","score":0.7670000195503235}],"concepts":[{"id":"https://openalex.org/C2776409635","wikidata":"https://www.wikidata.org/wiki/Q180556","display_name":"Helicobacter pylori","level":2,"score":0.8697417974472046},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8232619166374207},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.6971595287322998},{"id":"https://openalex.org/C139807058","wikidata":"https://www.wikidata.org/wiki/Q352374","display_name":"Adaptation (eye)","level":2,"score":0.6379220485687256},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5591546297073364},{"id":"https://openalex.org/C2910671496","wikidata":"https://www.wikidata.org/wiki/Q180556","display_name":"Helicobacter Infections","level":3,"score":0.5205972194671631},{"id":"https://openalex.org/C2780832600","wikidata":"https://www.wikidata.org/wiki/Q134684","display_name":"Helicobacter","level":3,"score":0.5105394124984741},{"id":"https://openalex.org/C2779137044","wikidata":"https://www.wikidata.org/wiki/Q7577827","display_name":"Spirillaceae","level":4,"score":0.42062634229660034},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3762439489364624},{"id":"https://openalex.org/C2778677798","wikidata":"https://www.wikidata.org/wiki/Q183130","display_name":"Gastritis","level":3,"score":0.30844101309776306},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.1051923930644989},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08463418483734131},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000222","descriptor_name":"Adaptation, Physiological","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005753","descriptor_name":"Gastric Mucosa","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005849","descriptor_name":"Gerbillinae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007501","descriptor_name":"Iron","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015964","descriptor_name":"Gene Expression Regulation, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016480","descriptor_name":"Helicobacter pylori","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D016480","descriptor_name":"Helicobacter pylori","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016480","descriptor_name":"Helicobacter pylori","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D016481","descriptor_name":"Helicobacter Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016481","descriptor_name":"Helicobacter Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D016481","descriptor_name":"Helicobacter Infections","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017673","descriptor_name":"Sodium Chloride, Dietary","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1128/iai.00918-15","doi":"https://doi.org/10.1128/iai.00918-15","is_oa":false,"landing_page_url":"https://doi.org/10.1128/iai.00918-15","pdf_url":null,"source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4645402","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4645402","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infect Immun","raw_type":"Text"},{"id":"pmid:26438795","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26438795","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and immunity","raw_type":"Journal Article"},{"id":"pmh:oai:alma.61MUN_INST:11136533470007891","doi":null,"is_oa":true,"landing_page_url":"https://researchportal.murdoch.edu.au/esploro/outputs/journalArticle/Helicobacter-pylori-adaptation-in-vivoin-response/991005544887907891","pdf_url":"https://researchportal.murdoch.edu.au/view/delivery/61MUN_INST/12136533460007891/13137137400007891","source":{"id":"https://openalex.org/S4306400274","display_name":"Murdoch University Research Portal","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I176790772","host_organization_name":"Murdoch University","host_organization_lineage":["https://openalex.org/I176790772"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"pmh:oai:pure.atira.dk:openaire/462fee57-521b-411f-a759-a161fa283668","doi":null,"is_oa":true,"landing_page_url":"https://admin.research-repository.uwa.edu.au/en/publications/462fee57-521b-411f-a759-a161fa283668","pdf_url":null,"source":{"id":"https://openalex.org/S4306402492","display_name":"UWA Profiles and Research Repository (UWA)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177877127","host_organization_name":"The University of Western Australia","host_organization_lineage":["https://openalex.org/I177877127"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Loh, J T, Gaddy, J A, Scott Algood, H M, Gaudieri, S, Mallal, S & Cover, T L 2015, 'Helicobacter pylori adaptation in vivo in response to a high-salt diet', Infection and Immunity, vol. 83, no. 12, pp. 4871-4883. https://doi.org/10.1128/IAI.00918-15","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:researchrepository.murdoch.edu.au:29336","doi":null,"is_oa":false,"landing_page_url":"http://researchrepository.murdoch.edu.au/id/eprint/29336/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400274","display_name":"Murdoch University Research Portal","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I176790772","host_organization_name":"Murdoch University","host_organization_lineage":["https://openalex.org/I176790772"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Loh, J.T., Gaddy, J.A., Algood, H.M.S., Gaudieri, S. &lt;http://researchrepository.murdoch.edu.au/view/author/Gaudieri, Silvana.html&gt;, Mallal, S. &lt;http://researchrepository.murdoch.edu.au/view/author/Mallal, Simon.html&gt; and Cover, T.L. (2015) Helicobacter pylori adaptation in vivoin response to a high salt diet. Infection and Immunity .","raw_type":"Journal Article"},{"id":"mag:2290583622","doi":null,"is_oa":false,"landing_page_url":"https://researchrepository.murdoch.edu.au/id/eprint/29336/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4645402","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4645402","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infect Immun","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1210968838","display_name":"Structure and function of Helicobacter pylori VacA","funder_award_id":"R01AI039657","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G1503321623","display_name":null,"funder_award_id":"IBX000915A","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G3070298961","display_name":null,"funder_award_id":"I01BX000915","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G3269002440","display_name":null,"funder_award_id":"P30 CA068485","funder_id":"https://openalex.org/F4320309601","funder_display_name":"Vanderbilt-Ingram Cancer Center"},{"id":"https://openalex.org/G5232245916","display_name":null,"funder_award_id":"IK2BX001701","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G606326072","display_name":null,"funder_award_id":"1IK2BX001701","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G6445545215","display_name":null,"funder_award_id":"I01 BX000627","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G6983389103","display_name":null,"funder_award_id":"2I01BX000627","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G7029265662","display_name":null,"funder_award_id":"P30 CA068485","funder_id":"https://openalex.org/F4320334532","funder_display_name":"Vanderbilt Digestive Diseases Research Center, Vanderbilt University Medical Center"},{"id":"https://openalex.org/G7642566612","display_name":null,"funder_award_id":"P30DK058404","funder_id":"https://openalex.org/F4320334532","funder_display_name":"Vanderbilt Digestive Diseases Research Center, Vanderbilt University Medical Center"},{"id":"https://openalex.org/G8159288582","display_name":null,"funder_award_id":"P30DK058404","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G8953775245","display_name":null,"funder_award_id":"CA068485","funder_id":"https://openalex.org/F4320309601","funder_display_name":"Vanderbilt-Ingram Cancer Center"},{"id":"https://openalex.org/G9000104831","display_name":null,"funder_award_id":"CA-116087","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000126444","display_name":null,"funder_award_id":"CA068485","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000862353","display_name":"Molecular and Cellular Basis for Digestive Diseases","funder_award_id":"P30DK058404","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G9000880732","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA068485","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000895449","display_name":"H. pylori-induced Inflammation and Gastric Cancer","funder_award_id":"P01CA116087","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320306127","display_name":"U.S. Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98"},{"id":"https://openalex.org/F4320309601","display_name":"Vanderbilt-Ingram Cancer Center","ror":"https://ror.org/05dq2gs74"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320334532","display_name":"Vanderbilt Digestive Diseases Research Center, Vanderbilt University Medical Center","ror":null},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2180725693.pdf","grobid_xml":"https://content.openalex.org/works/W2180725693.grobid-xml"},"referenced_works_count":61,"referenced_works":["https://openalex.org/W1514999190","https://openalex.org/W1517316728","https://openalex.org/W1571033920","https://openalex.org/W1621166403","https://openalex.org/W1792576847","https://openalex.org/W1898522767","https://openalex.org/W1965323568","https://openalex.org/W1969026716","https://openalex.org/W1970128919","https://openalex.org/W1973830631","https://openalex.org/W1978475106","https://openalex.org/W1983249081","https://openalex.org/W1991715652","https://openalex.org/W2002876374","https://openalex.org/W2006965406","https://openalex.org/W2011427563","https://openalex.org/W2013990983","https://openalex.org/W2015449706","https://openalex.org/W2018707425","https://openalex.org/W2029992296","https://openalex.org/W2035703380","https://openalex.org/W2040412134","https://openalex.org/W2047992675","https://openalex.org/W2049732161","https://openalex.org/W2051425239","https://openalex.org/W2059574805","https://openalex.org/W2078336838","https://openalex.org/W2081843568","https://openalex.org/W2085147304","https://openalex.org/W2087327203","https://openalex.org/W2106159202","https://openalex.org/W2107412520","https://openalex.org/W2108925945","https://openalex.org/W2111651784","https://openalex.org/W2111909489","https://openalex.org/W2114606976","https://openalex.org/W2121871451","https://openalex.org/W2124838552","https://openalex.org/W2127804720","https://openalex.org/W2127818778","https://openalex.org/W2131695415","https://openalex.org/W2133775476","https://openalex.org/W2137265693","https://openalex.org/W2140842331","https://openalex.org/W2141245744","https://openalex.org/W2142316694","https://openalex.org/W2142973131","https://openalex.org/W2144228398","https://openalex.org/W2145962148","https://openalex.org/W2148593013","https://openalex.org/W2151395223","https://openalex.org/W2152667563","https://openalex.org/W2155544436","https://openalex.org/W2156596439","https://openalex.org/W2157442946","https://openalex.org/W2162338734","https://openalex.org/W2169812063","https://openalex.org/W2171740941","https://openalex.org/W2171938017","https://openalex.org/W2172177565","https://openalex.org/W2291023071"],"related_works":["https://openalex.org/W4315754357","https://openalex.org/W1898522767","https://openalex.org/W2774054700","https://openalex.org/W4402315519","https://openalex.org/W2803144887","https://openalex.org/W2943900581","https://openalex.org/W2136031209","https://openalex.org/W2755314437","https://openalex.org/W2002876374","https://openalex.org/W1792576847"],"abstract_inverted_index":{"Helicobacter":[0],"pylori":[1,20,47,55,184],"exhibits":[2],"a":[3,35,50,63,67,90,99,121,144,148],"high":[4,153,173],"level":[5],"of":[6,18,26,34,105,115,155,176,182],"intraspecies":[7],"genetic":[8],"diversity.":[9],"In":[10],"this":[11,131,193],"study,":[12],"we":[13,30],"investigated":[14,31],"whether":[15],"the":[16,24,27,32,81,93,172],"diversification":[17,48],"H.":[19,46,54,163,183],"is":[21],"influenced":[22],"by":[23,73],"composition":[25],"diet.":[28],"Specifically,":[29],"effect":[33],"high-salt":[36,64,100,137,149],"diet":[37,65,69,101,150],"(a":[38],"known":[39],"risk":[40],"factor":[41],"for":[42,70,190],"gastric":[43,156],"adenocarcinoma)":[44],"on":[45],"within":[49],"host.":[51],"We":[52,142],"analyzed":[53],"strains":[56,86,95,185],"isolated":[57],"from":[58,87,96],"Mongolian":[59],"gerbils":[60],"fed":[61,89,98],"either":[62],"or":[66],"regular":[68,91],"4":[71],"months":[72],"proteomic":[74],"and":[75,84,111,139,158,166],"whole-genome":[76],"sequencing":[77],"methods.":[78],"Compared":[79],"to":[80,120,136,152,180],"input":[82],"strain":[83],"output":[85,94],"animals":[88,97,165],"diet,":[92],"produced":[102],"higher":[103],"levels":[104,154],"proteins":[106],"involved":[107],"in":[108,124,146,162,192],"iron":[109],"acquisition":[110],"oxidative-stress":[112],"resistance.":[113],"Several":[114],"these":[116,168],"changes":[117],"were":[118],"attributable":[119],"nonsynonymous":[122],"mutation":[123,132],"fur":[125],"(fur-R88H).":[126],"Further":[127],"experiments":[128],"indicated":[129],"that":[130,167,186],"conferred":[133],"increased":[134],"resistance":[135],"conditions":[138],"oxidative":[140,160],"stress.":[141],"propose":[143],"model":[145],"which":[147],"leads":[151],"inflammation":[157],"associated":[159],"stress":[161],"pylori-infected":[164],"conditions,":[169],"along":[170],"with":[171],"intraluminal":[174],"concentrations":[175],"sodium":[177],"chloride,":[178],"lead":[179],"selection":[181],"are":[187],"most":[188],"fit":[189],"growth":[191],"environment.":[194]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}
