{"id":"https://openalex.org/W2178355750","doi":"https://doi.org/10.1164/arrd.1987.135.6p2.s5","title":"Mast cell involvement in various inflammatory processes.","display_name":"Mast cell involvement in various inflammatory processes.","publication_year":1987,"publication_date":"1987-06-01","ids":{"openalex":"https://openalex.org/W2178355750","doi":"https://doi.org/10.1164/arrd.1987.135.6p2.s5","mag":"2178355750","pmid":"https://pubmed.ncbi.nlm.nih.gov/3109295"},"language":"en","primary_location":{"id":"pmid:3109295","doi":"https://doi.org/10.1164/arrd.1987.135.6p2.s5","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3109295","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American review of respiratory disease","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081608291","display_name":"John Bienenstock","orcid":"https://orcid.org/0000-0002-7677-0867","observed_orcids":["https://orcid.org/0000-0002-7677-0867"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Bienenstock","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024135924","display_name":"Motoaki Tomioka","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Tomioka","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112822962","display_name":"Ron H. Stead","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Stead","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102900245","display_name":"Peter B. Ernst","orcid":"https://orcid.org/0000-0001-7777-1813","observed_orcids":["https://orcid.org/0000-0001-7777-1813"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Ernst","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065277319","display_name":"Manel Jordana","orcid":"https://orcid.org/0000-0002-5861-5994","observed_orcids":["https://orcid.org/0000-0002-5861-5994"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Jordana","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005295653","display_name":"Jack Gauldie","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Gauldie","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008551153","display_name":"Jerry Dolovich","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Dolovich","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5060383332","display_name":"Judah A. Denburg","orcid":"https://orcid.org/0000-0001-5398-0063","observed_orcids":["https://orcid.org/0000-0001-5398-0063"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Denburg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.4279,"has_fulltext":false,"cited_by_count":45,"citation_normalized_percentile":{"value":0.82966714,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"135","issue":"6 Pt 2","first_page":"S5","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mast-cells","display_name":"mast cells","score":1.0},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.8930000066757202},{"id":"https://openalex.org/keywords/delayed-type-hypersensitivity","display_name":"delayed-type hypersensitivity","score":0.7639999985694885},{"id":"https://openalex.org/keywords/immediate-hypersensitivity","display_name":"immediate hypersensitivity","score":1.0},{"id":"https://openalex.org/keywords/granulomatous-inflammation","display_name":"granulomatous inflammation","score":0.9480000138282776},{"id":"https://openalex.org/keywords/phagocytosis","display_name":"phagocytosis","score":0.9779999852180481},{"id":"https://openalex.org/keywords/chemokinesis","display_name":"chemokinesis","score":0.9670000076293945},{"id":"https://openalex.org/keywords/tissue-repair","display_name":"tissue repair","score":0.8360000252723694},{"id":"https://openalex.org/keywords/fibroblast-function","display_name":"fibroblast function","score":0.8289999961853027},{"id":"https://openalex.org/keywords/fibrosis","display_name":"fibrosis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/mast-cell-degranulation","display_name":"mast cell degranulation","score":0.7789999842643738},{"id":"https://openalex.org/keywords/substance-p","display_name":"substance P","score":0.796999990940094},{"id":"https://openalex.org/keywords/mast-cell-neuron-interaction","display_name":"mast cell-neuron interaction","score":0.7739999890327454},{"id":"https://openalex.org/keywords/mast-cell-mediators","display_name":"mast cell mediators","score":0.6050000190734863}],"concepts":[{"id":"https://openalex.org/C2779726688","wikidata":"https://www.wikidata.org/wiki/Q191989","display_name":"Mast cell","level":2,"score":0.7378973364830017},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.610529899597168},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5548890829086304},{"id":"https://openalex.org/C189014844","wikidata":"https://www.wikidata.org/wiki/Q189118","display_name":"Cell type","level":3,"score":0.5234678983688354},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.520095705986023},{"id":"https://openalex.org/C160448771","wikidata":"https://www.wikidata.org/wiki/Q184726","display_name":"Phagocytosis","level":2,"score":0.4923356771469116},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4835655391216278},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.43487000465393066},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.4219300150871277},{"id":"https://openalex.org/C49802076","wikidata":"https://www.wikidata.org/wiki/Q5251810","display_name":"Degranulation","level":3,"score":0.4172738194465637},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3953951895236969},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2887159585952759},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.26932013034820557},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.18476969003677368},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001095","descriptor_name":"Arachidonic Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001491","descriptor_name":"Basophils","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003602","descriptor_name":"Cytotoxicity, Immunologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006099","descriptor_name":"Granuloma","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006968","descriptor_name":"Hypersensitivity, Delayed","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008407","descriptor_name":"Mast Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009424","descriptor_name":"Nervous System Physiological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010972","descriptor_name":"Platelet Activating Factor","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011509","descriptor_name":"Proteoglycans","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012221","descriptor_name":"Rhinitis, Allergic, Perennial","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D016718","descriptor_name":"Arachidonic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:3109295","doi":"https://doi.org/10.1164/arrd.1987.135.6p2.s5","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3109295","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American review of respiratory disease","raw_type":"Journal Article"},{"id":"mag:2178355750","doi":"https://doi.org/10.1164/arrd.1987.135.6p2.s5","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3109295","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320311526","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2960146085","https://openalex.org/W26781007","https://openalex.org/W4398155729","https://openalex.org/W4405224884","https://openalex.org/W2270613314","https://openalex.org/W2312691218","https://openalex.org/W2021068741","https://openalex.org/W1986562267","https://openalex.org/W2914274121","https://openalex.org/W7095674381"],"abstract_inverted_index":{"Mast":[0,81,139],"cells":[1,34,82,136,140],"from":[2,107],"different":[3,8,39,69],"tissue":[4],"sites":[5],"may":[6,95,141],"have":[7],"histochemical,":[9],"chemical,":[10],"and":[11,41,52,61,71,91,118,152,154],"functional":[12],"properties.":[13],"Whatever":[14],"the":[15,108,148],"basis":[16],"for":[17],"these":[18],"differences,":[19],"they":[20],"must":[21],"be":[22,96,113],"important":[23],"in":[24,37,47,53,67,85,158],"terms":[25],"of":[26,64,134],"their":[27,31],"biologic":[28],"significance.":[29],"Through":[30],"mediators,":[32],"mast":[33,135],"are":[35,83],"involved":[36,84,115],"many":[38,62],"acute":[40],"chronic":[42],"inflammatory":[43,159],"processes.":[44,160],"They":[45,56,110],"act":[46,143],"delayed":[48],"hypersensitivity,":[49,51],"immediate":[50],"granulomatous":[54],"reactions.":[55],"can":[57,119],"influence":[58],"phagocytosis,":[59],"chemokinesis,":[60],"aspects":[63],"immune":[65],"activity":[66],"several":[68],"T":[70,99],"B":[72],"cell":[73,156],"pathways,":[74],"to":[75,112,137],"mention":[76],"only":[77],"a":[78],"few":[79],"effects.":[80],"repair":[86],"processes":[87],"including":[88],"fibroblast":[89],"function":[90],"fibrosis.":[92],"Their":[93],"growth":[94],"influenced":[97],"by":[98],"cell-derived":[100],"factors":[101,105],"as":[102,104,144],"well":[103],"derived":[106],"epithelium.":[109],"appear":[111],"intimately":[114],"with":[116,123],"nerves":[117],"form":[120],"apparent":[121],"communications":[122],"neurones,":[124],"especially":[125],"those":[126],"containing":[127],"Substance":[128],"P,":[129],"which":[130],"causes":[131],"all":[132],"types":[133,157],"degranulate.":[138],"therefore":[142],"central":[145,149],"switchboards":[146],"between":[147],"nervous":[150],"system":[151],"migrating":[153],"sessile":[155]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}