{"id":"https://openalex.org/W2176186412","doi":"https://doi.org/10.1152/ajpgi.1999.277.6.g1108","title":"The cytoskeleton of digestive epithelia in health and disease","display_name":"The cytoskeleton of digestive epithelia in health and disease","publication_year":1999,"publication_date":"1999-12-01","ids":{"openalex":"https://openalex.org/W2176186412","doi":"https://doi.org/10.1152/ajpgi.1999.277.6.g1108","mag":"2176186412","pmid":"https://pubmed.ncbi.nlm.nih.gov/10600809"},"language":"en","primary_location":{"id":"doi:10.1152/ajpgi.1999.277.6.g1108","doi":"https://doi.org/10.1152/ajpgi.1999.277.6.g1108","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpgi.1999.277.6.g1108","pdf_url":null,"source":{"id":"https://openalex.org/S34136372","display_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","issn_l":"0193-1857","issn":["0193-1857","1522-1547"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101522120","display_name":"Nam\u2010On Ku","orcid":"https://orcid.org/0000-0003-3850-0126","observed_orcids":["https://orcid.org/0000-0003-3850-0126"]},"institutions":[{"id":"https://openalex.org/I204866599","display_name":"VA Palo Alto Health Care System","ror":"https://ror.org/00nr17z89","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I204866599","https://openalex.org/I2799886695","https://openalex.org/I4210125474"]},{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nam-On Ku","raw_affiliation_strings":["Department of Medicine, Veterans Affairs Palo Alto Health Care System, Palo Alto 94304; and the Digestive Disease Center, Stanford University School of Medicine, Stanford, California 94305","the Digestive Disease Center, Stanford University School of Medicine, Stanford, California 94305"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Veterans Affairs Palo Alto Health Care System, Palo Alto 94304; and the Digestive Disease Center, Stanford University School of Medicine, Stanford, California 94305","institution_ids":["https://openalex.org/I204866599","https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"raw_affiliation_string":"the Digestive Disease Center, Stanford University School of Medicine, Stanford, California 94305","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103075292","display_name":"Xiangjun Zhou","orcid":"https://orcid.org/0000-0002-9086-6996","observed_orcids":["https://orcid.org/0000-0002-9086-6996"]},"institutions":[{"id":"https://openalex.org/I204866599","display_name":"VA Palo Alto Health Care System","ror":"https://ror.org/00nr17z89","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I204866599","https://openalex.org/I2799886695","https://openalex.org/I4210125474"]},{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiangjun Zhou","raw_affiliation_strings":["Department of Medicine, Veterans Affairs Palo Alto Health Care System, Palo Alto 94304; and the Digestive Disease Center, Stanford University School of Medicine, Stanford, California 94305","the Digestive Disease Center, Stanford University School of Medicine, Stanford, California 94305"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Veterans Affairs Palo Alto Health Care System, Palo Alto 94304; and the Digestive Disease Center, Stanford University School of Medicine, Stanford, California 94305","institution_ids":["https://openalex.org/I204866599","https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"raw_affiliation_string":"the Digestive Disease Center, Stanford University School of Medicine, Stanford, California 94305","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066897632","display_name":"Diana M. Toivola","orcid":"https://orcid.org/0000-0001-7165-9839","observed_orcids":["https://orcid.org/0000-0001-7165-9839"]},"institutions":[{"id":"https://openalex.org/I204866599","display_name":"VA Palo Alto Health Care System","ror":"https://ror.org/00nr17z89","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I204866599","https://openalex.org/I2799886695","https://openalex.org/I4210125474"]},{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Diana M. Toivola","raw_affiliation_strings":["Department of Medicine, Veterans Affairs Palo Alto Health Care System, Palo Alto 94304; and the Digestive Disease Center, Stanford University School of Medicine, Stanford, California 94305","the Digestive Disease Center, Stanford University School of Medicine, Stanford, California 94305"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Veterans Affairs Palo Alto Health Care System, Palo Alto 94304; and the Digestive Disease Center, Stanford University School of Medicine, Stanford, California 94305","institution_ids":["https://openalex.org/I204866599","https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"raw_affiliation_string":"the Digestive Disease Center, Stanford University School of Medicine, Stanford, California 94305","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007337339","display_name":"M. Bishr Omary","orcid":"https://orcid.org/0000-0002-8624-2347","observed_orcids":["https://orcid.org/0000-0002-8624-2347"]},"institutions":[{"id":"https://openalex.org/I204866599","display_name":"VA Palo Alto Health Care System","ror":"https://ror.org/00nr17z89","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I204866599","https://openalex.org/I2799886695","https://openalex.org/I4210125474"]},{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Bishr Omary","raw_affiliation_strings":["Department of Medicine, Veterans Affairs Palo Alto Health Care System, Palo Alto 94304; and the Digestive Disease Center, Stanford University School of Medicine, Stanford, California 94305","the Digestive Disease Center, Stanford University School of Medicine, Stanford, California 94305"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Veterans Affairs Palo Alto Health Care System, Palo Alto 94304; and the Digestive Disease Center, Stanford University School of Medicine, Stanford, California 94305","institution_ids":["https://openalex.org/I204866599","https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"raw_affiliation_string":"the Digestive Disease Center, Stanford University School of Medicine, Stanford, California 94305","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.002,"has_fulltext":false,"cited_by_count":186,"citation_normalized_percentile":{"value":0.85655464,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"277","issue":"6","first_page":"G1108","last_page":"G1137"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11650","display_name":"Skin and Cellular Biology Research","score":0.9535999894142151,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11650","display_name":"Skin and Cellular Biology Research","score":0.9535999894142151,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.04280000180006027,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cytoskeleton","display_name":"cytoskeleton","score":0.9729999899864197},{"id":"https://openalex.org/keywords/actin-filaments","display_name":"F-actin","score":0.9829999804496765},{"id":"https://openalex.org/keywords/microtubules","display_name":"microtubules","score":0.9750000238418579},{"id":"https://openalex.org/keywords/intermediate-filaments","display_name":"intermediate filaments","score":1.0},{"id":"https://openalex.org/keywords/actin","display_name":"actin","score":0.9779999852180481},{"id":"https://openalex.org/keywords/tubulin","display_name":"tubulin","score":0.996999979019165},{"id":"https://openalex.org/keywords/keratin","display_name":"keratin","score":0.8769999742507935},{"id":"https://openalex.org/keywords/signal-transduction","display_name":"signal transduction","score":0.8299999833106995},{"id":"https://openalex.org/keywords/linker-proteins","display_name":"linker proteins","score":0.8019999861717224},{"id":"https://openalex.org/keywords/gastrointestinal-diseases","display_name":"gastrointestinal diseases","score":0.8180000185966492}],"concepts":[{"id":"https://openalex.org/C142669718","wikidata":"https://www.wikidata.org/wiki/Q154626","display_name":"Cytoskeleton","level":3,"score":0.789076566696167},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6657355427742004},{"id":"https://openalex.org/C20418707","wikidata":"https://www.wikidata.org/wiki/Q189933","display_name":"Microtubule","level":2,"score":0.6602023243904114},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6185043454170227},{"id":"https://openalex.org/C84425145","wikidata":"https://www.wikidata.org/wiki/Q422492","display_name":"Tubulin","level":3,"score":0.47329726815223694},{"id":"https://openalex.org/C189040839","wikidata":"https://www.wikidata.org/wiki/Q329638","display_name":"Microfilament","level":4,"score":0.45040684938430786},{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.44601938128471375},{"id":"https://openalex.org/C78383274","wikidata":"https://www.wikidata.org/wiki/Q421987","display_name":"Intermediate filament","level":4,"score":0.44452497363090515},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4432770311832428},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.43732523918151855},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2339739203453064},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.22451305389404297}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003599","descriptor_name":"Cytoskeleton","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003599","descriptor_name":"Cytoskeleton","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003599","descriptor_name":"Cytoskeleton","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004064","descriptor_name":"Digestive System","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004064","descriptor_name":"Digestive System","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004064","descriptor_name":"Digestive System","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004068","descriptor_name":"Digestive System Physiological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004068","descriptor_name":"Digestive System Physiological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004068","descriptor_name":"Digestive System Physiological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D005767","descriptor_name":"Gastrointestinal Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005767","descriptor_name":"Gastrointestinal Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005767","descriptor_name":"Gastrointestinal Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1152/ajpgi.1999.277.6.g1108","doi":"https://doi.org/10.1152/ajpgi.1999.277.6.g1108","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpgi.1999.277.6.g1108","pdf_url":null,"source":{"id":"https://openalex.org/S34136372","display_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","issn_l":"0193-1857","issn":["0193-1857","1522-1547"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","raw_type":"journal-article"},{"id":"pmid:10600809","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10600809","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of physiology","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:publications/42e47267-ea25-4ae3-8578-ee99e0707cc0","doi":null,"is_oa":false,"landing_page_url":"https://research.abo.fi/en/publications/42e47267-ea25-4ae3-8578-ee99e0707cc0","pdf_url":null,"source":{"id":"https://openalex.org/S4406923060","display_name":"\u00c5bo Akademi University Research Portal","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NO, K, Zhou, XJ, Toivola, D & Omary, MB 1999, 'The cytoskeleton of digestive epithelia in health and disease', AJP - Gastrointestinal and Liver Physiology, vol. 277, no. 6, pp. G1108\u2013G1137. https://doi.org/10.1152/ajpgi.1999.277.6.G1108","raw_type":"info:eu-repo/semantics/review"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.6600000262260437,"id":"https://metadata.un.org/sdg/15","display_name":"Life on land"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2196341103","display_name":null,"funder_award_id":"DK47918","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G4440821290","display_name":"Keratin Biology and Disease Aspects in Simple Epithelia","funder_award_id":"7r01dk047918-26","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G685740053","display_name":null,"funder_award_id":"DK52951","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":283,"referenced_works":["https://openalex.org/W32148982","https://openalex.org/W44987209","https://openalex.org/W75575892","https://openalex.org/W105454779","https://openalex.org/W118234592","https://openalex.org/W134489368","https://openalex.org/W185131684","https://openalex.org/W339490310","https://openalex.org/W406933732","https://openalex.org/W1487741670","https://openalex.org/W1515092449","https://openalex.org/W1515568468","https://openalex.org/W1516756689","https://openalex.org/W1546173464","https://openalex.org/W1561407320","https://openalex.org/W1573139030","https://openalex.org/W1580377051","https://openalex.org/W1585980551","https://openalex.org/W1603724904","https://openalex.org/W1624606257","https://openalex.org/W1736997494","https://openalex.org/W1750780172","https://openalex.org/W1763709729","https://openalex.org/W1771666756","https://openalex.org/W1790736933","https://openalex.org/W1792974413","https://openalex.org/W1796432089","https://openalex.org/W1824067573","https://openalex.org/W1858835183","https://openalex.org/W1866995360","https://openalex.org/W1934714969","https://openalex.org/W1955592678","https://openalex.org/W1963531178","https://openalex.org/W1963851313","https://openalex.org/W1966808185","https://openalex.org/W1969609019","https://openalex.org/W1972146939","https://openalex.org/W1974007194","https://openalex.org/W1975045686","https://openalex.org/W1976171313","https://openalex.org/W1976347030","https://openalex.org/W1976852537","https://openalex.org/W1977640511","https://openalex.org/W1978349586","https://openalex.org/W1978831709","https://openalex.org/W1980851644","https://openalex.org/W1984236884","https://openalex.org/W1984610550","https://openalex.org/W1984902423","https://openalex.org/W1985151525","https://openalex.org/W1986393243","https://openalex.org/W1986477988","https://openalex.org/W1986887962","https://openalex.org/W1987861844","https://openalex.org/W1989010734","https://openalex.org/W1989591445","https://openalex.org/W1989705574","https://openalex.org/W1990031184","https://openalex.org/W1990963263","https://openalex.org/W1991030946","https://openalex.org/W1991578760","https://openalex.org/W1992478517","https://openalex.org/W1993941425","https://openalex.org/W1994162083","https://openalex.org/W1994413881","https://openalex.org/W1995179154","https://openalex.org/W1995742610","https://openalex.org/W1995757732","https://openalex.org/W1995930436","https://openalex.org/W1997122736","https://openalex.org/W1997986612","https://openalex.org/W1998115472","https://openalex.org/W1999951243","https://openalex.org/W1999980623","https://openalex.org/W2000733059","https://openalex.org/W2001281232","https://openalex.org/W2001953889","https://openalex.org/W2004208265","https://openalex.org/W2004513287","https://openalex.org/W2007501186","https://openalex.org/W2007660627","https://openalex.org/W2008529164","https://openalex.org/W2008610112","https://openalex.org/W2010268291","https://openalex.org/W2010848611","https://openalex.org/W2013660714","https://openalex.org/W2014629508","https://openalex.org/W2016208693","https://openalex.org/W2016693266","https://openalex.org/W2017609866","https://openalex.org/W2017785026","https://openalex.org/W2018251672","https://openalex.org/W2019589940","https://openalex.org/W2021015773","https://openalex.org/W2021275530","https://openalex.org/W2021894466","https://openalex.org/W2022893363","https://openalex.org/W2023114874","https://openalex.org/W2023687572","https://openalex.org/W2023931788","https://openalex.org/W2024281628","https://openalex.org/W2025678616","https://openalex.org/W2026314298","https://openalex.org/W2027584489","https://openalex.org/W2030828004","https://openalex.org/W2034463209","https://openalex.org/W2034499208","https://openalex.org/W2034626424","https://openalex.org/W2034718650","https://openalex.org/W2038195441","https://openalex.org/W2039320206","https://openalex.org/W2040103754","https://openalex.org/W2040645020","https://openalex.org/W2040696292","https://openalex.org/W2043229909","https://openalex.org/W2045923054","https://openalex.org/W2046476770","https://openalex.org/W2046560218","https://openalex.org/W2046653860","https://openalex.org/W2046887726","https://openalex.org/W2047672708","https://openalex.org/W2048426630","https://openalex.org/W2048599697","https://openalex.org/W2049168649","https://openalex.org/W2049179639","https://openalex.org/W2049279039","https://openalex.org/W2049715678","https://openalex.org/W2050865324","https://openalex.org/W2051017167","https://openalex.org/W2051227783","https://openalex.org/W2052110964","https://openalex.org/W2052386537","https://openalex.org/W2052642128","https://openalex.org/W2052759051","https://openalex.org/W2052822447","https://openalex.org/W2053299834","https://openalex.org/W2054323309","https://openalex.org/W2054675849","https://openalex.org/W2056613463","https://openalex.org/W2057796711","https://openalex.org/W2058336142","https://openalex.org/W2058943343","https://openalex.org/W2059398027","https://openalex.org/W2060064038","https://openalex.org/W2060834775","https://openalex.org/W2060909091","https://openalex.org/W2061986589","https://openalex.org/W2062375210","https://openalex.org/W2062634275","https://openalex.org/W2063484111","https://openalex.org/W2063875318","https://openalex.org/W2064102546","https://openalex.org/W2065227756","https://openalex.org/W2065819788","https://openalex.org/W2067275681","https://openalex.org/W2067488942","https://openalex.org/W2068067700","https://openalex.org/W2068955840","https://openalex.org/W2069078564","https://openalex.org/W2070275392","https://openalex.org/W2072731626","https://openalex.org/W2073852580","https://openalex.org/W2073891485","https://openalex.org/W2074678011","https://openalex.org/W2075429195","https://openalex.org/W2075963368","https://openalex.org/W2076993988","https://openalex.org/W2077087490","https://openalex.org/W2077337127","https://openalex.org/W2077718395","https://openalex.org/W2078546411","https://openalex.org/W2079069336","https://openalex.org/W2082067280","https://openalex.org/W2082813263","https://openalex.org/W2083501063","https://openalex.org/W2084785013","https://openalex.org/W2085247045","https://openalex.org/W2085503165","https://openalex.org/W2085707216","https://openalex.org/W2085967893","https://openalex.org/W2087998710","https://openalex.org/W2089537333","https://openalex.org/W2091005897","https://openalex.org/W2091956705","https://openalex.org/W2092834961","https://openalex.org/W2095140635","https://openalex.org/W2096201309","https://openalex.org/W2096483656","https://openalex.org/W2099322911","https://openalex.org/W2101416170","https://openalex.org/W2102407282","https://openalex.org/W2103831817","https://openalex.org/W2104555172","https://openalex.org/W2106054012","https://openalex.org/W2107995151","https://openalex.org/W2109084265","https://openalex.org/W2109952947","https://openalex.org/W2110174748","https://openalex.org/W2110799552","https://openalex.org/W2111487813","https://openalex.org/W2111588458","https://openalex.org/W2112315450","https://openalex.org/W2112630320","https://openalex.org/W2112751496","https://openalex.org/W2115033587","https://openalex.org/W2117931147","https://openalex.org/W2120140643","https://openalex.org/W2122007306","https://openalex.org/W2122412289","https://openalex.org/W2122631316","https://openalex.org/W2123259196","https://openalex.org/W2125225672","https://openalex.org/W2126048177","https://openalex.org/W2126582065","https://openalex.org/W2126588654","https://openalex.org/W2127779172","https://openalex.org/W2128050586","https://openalex.org/W2128134950","https://openalex.org/W2128341772","https://openalex.org/W2128628596","https://openalex.org/W2130172628","https://openalex.org/W2130851152","https://openalex.org/W2131736369","https://openalex.org/W2133181593","https://openalex.org/W2135329719","https://openalex.org/W2135723950","https://openalex.org/W2137749186","https://openalex.org/W2147512361","https://openalex.org/W2148248939","https://openalex.org/W2149743976","https://openalex.org/W2151048160","https://openalex.org/W2152335956","https://openalex.org/W2153867336","https://openalex.org/W2154157434","https://openalex.org/W2154625078","https://openalex.org/W2154739968","https://openalex.org/W2155674048","https://openalex.org/W2156819631","https://openalex.org/W2156820197","https://openalex.org/W2157319245","https://openalex.org/W2158044026","https://openalex.org/W2158081637","https://openalex.org/W2158926036","https://openalex.org/W2159643400","https://openalex.org/W2159980792","https://openalex.org/W2161744897","https://openalex.org/W2162960688","https://openalex.org/W2163772621","https://openalex.org/W2165721689","https://openalex.org/W2168760539","https://openalex.org/W2169590280","https://openalex.org/W2170062483","https://openalex.org/W2171239820","https://openalex.org/W2171308921","https://openalex.org/W2171403233","https://openalex.org/W2171969748","https://openalex.org/W2181081470","https://openalex.org/W2181763243","https://openalex.org/W2187456383","https://openalex.org/W2187980028","https://openalex.org/W2218922061","https://openalex.org/W2284013506","https://openalex.org/W2287728217","https://openalex.org/W2313081412","https://openalex.org/W2321438790","https://openalex.org/W2324012034","https://openalex.org/W2324833796","https://openalex.org/W2394693425","https://openalex.org/W2398253505","https://openalex.org/W2408710509","https://openalex.org/W2410364843","https://openalex.org/W2410836602","https://openalex.org/W2415711028","https://openalex.org/W2417460958","https://openalex.org/W2419038469","https://openalex.org/W2469844221","https://openalex.org/W2475287743","https://openalex.org/W4213141530","https://openalex.org/W4231136244","https://openalex.org/W4231177810","https://openalex.org/W4238376026","https://openalex.org/W4285719527","https://openalex.org/W4313331821"],"related_works":["https://openalex.org/W2471276139","https://openalex.org/W2009085363","https://openalex.org/W2352927845","https://openalex.org/W2271407082","https://openalex.org/W1594559229","https://openalex.org/W2081451190","https://openalex.org/W1531816097","https://openalex.org/W1998274339","https://openalex.org/W2007117627","https://openalex.org/W1999411716"],"abstract_inverted_index":{"The":[0,35,103,172],"mammalian":[1],"cell":[2,25,116],"cytoskeleton":[3,36],"consists":[4,40],"of":[5,9,21,37,41,62,71,93,108,127,135,168,174,191],"a":[6,14,19,59,124],"diverse":[7],"group":[8],"fibrillar":[10],"elements":[11,180],"that":[12,144,161,176,193],"play":[13,146],"pivotal":[15],"role":[16,143],"in":[17,100,115,147],"mediating":[18],"number":[20,61],"digestive":[22,66,101,185],"and":[23,33,52,79,90,153],"nondigestive":[24],"functions,":[26],"including":[27],"secretion,":[28],"absorption,":[29],"motility,":[30],"mechanical":[31],"integrity,":[32],"mitosis.":[34],"higher-eukaryotic":[38],"cells":[39],"three":[42,73,95,167],"highly":[43],"abundant":[44],"major":[45,96],"protein":[46,74,98,110],"families:":[47],"microfilaments":[48],"(MF),":[49],"microtubules":[50],"(MT),":[51],"intermediate":[53],"filaments":[54],"(IF),":[55,152],"as":[56,58,181],"well":[57],"growing":[60,125],"associated":[63,128],"proteins.":[64],"Within":[65],"epithelia,":[67],"the":[68,85,94,133,141],"prototype":[69],"members":[70],"these":[72,109,169],"families":[75],"are":[76,112],"actins,":[77],"tubulins,":[78],"keratins,":[80],"respectively.":[81],"This":[82],"review":[83],"highlights":[84],"important":[86],"structural,":[87],"regulatory,":[88],"functional,":[89],"unique":[91,189],"features":[92],"cytoskeletal":[97,179],"groups":[99,111,170],"epithelia.":[102],"emerging":[104],"exciting":[105],"biological":[106],"aspects":[107],"their":[113,154],"involvement":[114],"signaling":[117],"via":[118,157],"direct":[119],"or":[120,164],"indirect":[121],"interaction":[122],"with":[123],"list":[126],"proteins":[129,160],"(MF,":[130],"MT,":[131],"IF),":[132],"identification":[134],"several":[136,158],"disease-causing":[137],"mutations":[138],"(IF,":[139],"MF),":[140],"functional":[142,155],"they":[145],"protection":[148],"from":[149],"environmental":[150],"stresses":[151],"integration":[156],"linker":[159],"bridge":[162],"two":[163],"potentially":[165],"all":[166],"together.":[171],"use":[173],"agents":[175],"target":[177],"specific":[178],"therapeutic":[182],"modalities":[183],"for":[184],"diseases":[186],"offers":[187],"potential":[188],"areas":[190],"intervention":[192],"remain":[194],"to":[195],"be":[196],"fully":[197],"explored.":[198]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":14},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":10}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}
