{"id":"https://openalex.org/W2175879571","doi":"https://doi.org/10.1161/circoutcomes.7.suppl_1.157","title":"Abstract 157: Use of a Novel Risk Score in the Emergency Department Discriminates Acute Coronary Syndrome Among Chest Pain Patients with Known Coronary Artery Disease","display_name":"Abstract 157: Use of a Novel Risk Score in the Emergency Department Discriminates Acute Coronary Syndrome Among Chest Pain Patients with Known Coronary Artery Disease","publication_year":2014,"publication_date":"2014-07-01","ids":{"openalex":"https://openalex.org/W2175879571","doi":"https://doi.org/10.1161/circoutcomes.7.suppl_1.157","mag":"2175879571"},"language":"en","primary_location":{"id":"doi:10.1161/circoutcomes.7.suppl_1.157","doi":"https://doi.org/10.1161/circoutcomes.7.suppl_1.157","is_oa":false,"landing_page_url":"https://doi.org/10.1161/circoutcomes.7.suppl_1.157","pdf_url":null,"source":{"id":"https://openalex.org/S52278559","display_name":"Circulation Cardiovascular Quality and Outcomes","issn_l":"1941-7705","issn":["1941-7705","1941-7713"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation: Cardiovascular Quality and Outcomes","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083186415","display_name":"Matthew T Crim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew T Crim","raw_affiliation_strings":["The Johns Hopkins Hosp, Baltimore, MD","Matthew T Crim"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins Hosp, Baltimore, MD","institution_ids":["https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Matthew T Crim","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008873543","display_name":"Frederick Kofi Korley","orcid":"https://orcid.org/0000-0003-4920-8278","observed_orcids":["https://orcid.org/0000-0003-4920-8278"]},"institutions":[{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frederick K Korley","raw_affiliation_strings":["The Johns Hopkins Hosp, Baltimore, MD","Frederick K Korley"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins Hosp, Baltimore, MD","institution_ids":["https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Frederick K Korley","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106409505","display_name":"Scott A. Berkowitz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott A Berkowitz","raw_affiliation_strings":["The Johns Hopkins Hosp, Baltimore, MD","Scott A Berkowitz"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins Hosp, Baltimore, MD","institution_ids":["https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Scott A Berkowitz","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075327245","display_name":"Mustapha O. Saheed","orcid":"https://orcid.org/0009-0003-1324-7141","observed_orcids":["https://orcid.org/0009-0003-1324-7141"]},"institutions":[{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mustapha Saheed","raw_affiliation_strings":["The Johns Hopkins Hosp, Baltimore, MD","Mustapha Saheed"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins Hosp, Baltimore, MD","institution_ids":["https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Mustapha Saheed","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jason Miller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason Miller","raw_affiliation_strings":["The Johns Hopkins Hosp, Baltimore, MD","Jason Miller"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins Hosp, Baltimore, MD","institution_ids":["https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Jason Miller","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038700492","display_name":"Amy Deutschendorf","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy Deutschendorf","raw_affiliation_strings":["The Johns Hopkins Hosp, Baltimore, MD","Amy Deutschendorf"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins Hosp, Baltimore, MD","institution_ids":["https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Amy Deutschendorf","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050107961","display_name":"Gary Gerstenblith","orcid":"https://orcid.org/0000-0001-6046-6812","observed_orcids":["https://orcid.org/0000-0001-6046-6812"]},"institutions":[{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gary Gerstenblith","raw_affiliation_strings":["The Johns Hopkins Hosp, Baltimore, MD","Gary Gerstenblith"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins Hosp, Baltimore, MD","institution_ids":["https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Gary Gerstenblith","institution_ids":[]}]},{"author_position":"last","author":{"id":null,"display_name":"Peter Hill","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter Hill","raw_affiliation_strings":["The Johns Hopkins Hosp, Baltimore, MD","Peter Hill"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins Hosp, Baltimore, MD","institution_ids":["https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Peter Hill","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210150714"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"7","issue":"suppl_1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11095","display_name":"Emergency and Acute Care Studies","score":0.011300000362098217,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-coronary-syndrome","display_name":"acute coronary syndrome","score":0.9980000257492065},{"id":"https://openalex.org/keywords/chest-pain","display_name":"chest pain","score":0.7260000109672546},{"id":"https://openalex.org/keywords/risk-score","display_name":"risk score","score":0.8830000162124634},{"id":"https://openalex.org/keywords/troponin-i","display_name":"troponin I","score":0.8640000224113464},{"id":"https://openalex.org/keywords/emergency-department","display_name":"emergency department","score":0.6840000152587891},{"id":"https://openalex.org/keywords/diagnostic-discrimination","display_name":"diagnostic discrimination","score":0.5509999990463257},{"id":"https://openalex.org/keywords/length-of-hospital-stay","display_name":"length of hospital stay","score":0.6079999804496765},{"id":"https://openalex.org/keywords/hospitalization-costs","display_name":"hospital costs","score":0.746999979019165},{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.6980000138282776},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.7829999923706055},{"id":"https://openalex.org/keywords/aspirin-use","display_name":"aspirin use","score":0.8009999990463257},{"id":"https://openalex.org/keywords/women","display_name":"women","score":0.3199999928474426},{"id":"https://openalex.org/keywords/african-americans","display_name":"African Americans","score":0.8970000147819519},{"id":"https://openalex.org/keywords/risk-stratification","display_name":"risk stratification","score":0.38600000739097595}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.939394474029541},{"id":"https://openalex.org/C2777698277","wikidata":"https://www.wikidata.org/wiki/Q266018","display_name":"Acute coronary syndrome","level":3,"score":0.835657000541687},{"id":"https://openalex.org/C2778704086","wikidata":"https://www.wikidata.org/wiki/Q693058","display_name":"Chest pain","level":2,"score":0.8259899020195007},{"id":"https://openalex.org/C2780724011","wikidata":"https://www.wikidata.org/wiki/Q1295316","display_name":"Emergency department","level":2,"score":0.7973121404647827},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6915658712387085},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.663457989692688},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.6420559883117676},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5931336283683777},{"id":"https://openalex.org/C36036425","wikidata":"https://www.wikidata.org/wiki/Q7846262","display_name":"Troponin","level":3,"score":0.5357133150100708},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.533997654914856},{"id":"https://openalex.org/C45393284","wikidata":"https://www.wikidata.org/wiki/Q191012","display_name":"Conventional PCI","level":3,"score":0.5323059558868408},{"id":"https://openalex.org/C2779464278","wikidata":"https://www.wikidata.org/wiki/Q7317735","display_name":"Revascularization","level":3,"score":0.5102789402008057},{"id":"https://openalex.org/C144469398","wikidata":"https://www.wikidata.org/wiki/Q24785650","display_name":"Troponin T","level":3,"score":0.4303140342235565},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1161/circoutcomes.7.suppl_1.157","doi":"https://doi.org/10.1161/circoutcomes.7.suppl_1.157","is_oa":false,"landing_page_url":"https://doi.org/10.1161/circoutcomes.7.suppl_1.157","pdf_url":null,"source":{"id":"https://openalex.org/S52278559","display_name":"Circulation Cardiovascular Quality and Outcomes","issn_l":"1941-7705","issn":["1941-7705","1941-7713"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation: Cardiovascular Quality and Outcomes","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2554923484","https://openalex.org/W4395040007","https://openalex.org/W7055212327","https://openalex.org/W2132630037","https://openalex.org/W2123698362","https://openalex.org/W2133598340","https://openalex.org/W2341873160","https://openalex.org/W2337947720","https://openalex.org/W4286560890","https://openalex.org/W148387897"],"abstract_inverted_index":{"Background:":[0],"Patients":[1],"with":[2,14,36,83,90,145,151,297,361,430,437,459],"known":[3,84,431],"coronary":[4,38,125],"artery":[5],"disease":[6,270],"(CAD)":[7],"presenting":[8,86,433],"to":[9,18,26,87,94,104,110,278,415,434],"the":[10,27,44,52,88,105,138,156,198,225,242,249,279,307,314,387,393,416,435,465],"Emergency":[11],"Department":[12],"(ED)":[13],"chest":[15,91,438],"pain":[16,92],"thought":[17,93],"be":[19,95],"of":[20,46,57,80,96,100,119,182,197,208,267,304,317,355,364,406,454,467],"ischemic":[21,97],"origin":[22],"are":[23,33],"often":[24],"admitted":[25,103],"hospital,":[28],"yet":[29],"less":[30],"than":[31,263,334,403],"half":[32],"eventually":[34,192],"diagnosed":[35,193],"acute":[37],"syndrome":[39],"(ACS).":[40],"We":[41],"assessed":[42,144],"whether":[43],"use":[45,327],"a":[47,76,129,180,203,419,444],"novel":[48,231,379],"risk":[49,232,380,456],"score":[50,381],"in":[51,194,241,248,386,392],"ED":[53,89,280,436],"could":[54],"discriminate":[55],"which":[56,221],"these":[58],"high-risk":[59],"patients":[60,82,177,201,429],"actually":[61],"do":[62,64],"or":[63,128,289],"not":[65],"have":[66],"ACS.":[67],"Methods":[68],"and":[69,169,210,272,295,347,410,426,448,471],"Results:":[70],"Chart":[71],"review":[72],"was":[73,115,135,191,313,359,371],"performed":[74],"on":[75],"prospectively":[77],"defined":[78,116],"cohort":[79,164],"142":[81],"CAD":[85,114,432],"origin,":[98],"all":[99],"whom":[101],"were":[102,143],"hospital":[106,161,215],"from":[107],"December":[108],"2012":[109],"April":[111],"2013.":[112],"Known":[113],"as":[117,153,370],"history":[118,181,266,405],"myocardial":[120],"infarction,":[121],"PCI,":[122,185],"CABG,":[123,187],"angiographic":[124],"stenosis":[126],">50%,":[127],"positive":[130],"stress":[131],"test.":[132],"Troponin":[133],"I":[134,238,311,385],"measured":[136],"using":[137],"Beckman":[139],"Coulter":[140],"assay.":[141],"Variables":[142],"logistic":[146],"regression":[147],"for":[148,224,422,446,451],"their":[149],"association":[150],"ACS":[152,190,294,318,365,425],"determined":[154],"by":[155,324],"inpatient":[157,213],"attending":[158],"physician":[159,219],"at":[160,276,413],"discharge.":[162],"The":[163,353],"included":[165],"59":[166],"women":[167],"(42%)":[168],"90":[170],"African":[171],"American":[172],"individuals":[173],"(63%).":[174],"One-hundred":[175],"sixteen":[176],"(82%)":[178],"had":[179,202],"revascularization":[183],"(104":[184],"53":[186],"41":[188],"both).":[189],"43":[195],"(30%)":[196],"patients.":[199,229],"Non-ACS":[200],"2.8":[204],"day":[205],"average":[206,212],"length":[207],"stay":[209],"$9,908":[211],"(post-ED)":[214],"charges":[216],"(not":[217],"including":[218,234,382],"fees),":[220],"is":[222,418],"$980,926":[223],"99":[226],"(70%)":[227],"non-ACS":[228,296,427],"A":[230,378],"score,":[233,457],"(1)":[235],"elevated":[236,383],"troponin":[237,310,384],"(>0.05":[239],"ng/mL)":[240],"ED,":[243,250,388,394,417],"(2)":[244],"dynamic":[245,340,389],"ECG":[246,341,390],"changes":[247,342,391],"(3)":[251],"body":[252,395],"mass":[253,396],"index":[254],"(BMI),":[255],"(4)":[256],"home":[257,325,398],"aspirin":[258,326,399],"use,":[259,400],"(5)":[260],"age":[261,332,401],"older":[262,333,402],"65,":[264,404],"(6)":[265],"chronic":[268,407],"kidney":[269,408],"(CKD),":[271],"(7)":[273],"associated":[274,357,360,411,472],"illness":[275,358,412],"presentation":[277,414],"(anemia,":[281],"arrhythmia,":[282],"hypertension,":[283],"infection,":[284],"COPD":[285],"exacerbation,":[286],"diabetic":[287],"ketoacidosis":[288],"hyperosmolar":[290],"hyperglycemic":[291],"state),":[292],"discriminated":[293],"an":[298,356],"area":[299],"under":[300],"ROC":[301],"curve":[302],"(AUC)":[303],"0.829.":[305],"In":[306],"multi-variable":[308],"regression,":[309],"elevation":[312],"most":[315],"predictive":[316],"(OR":[319,328,336,343,349,366,373],"7.22,":[320],"p":[321,330,338,345,351,368,375],"<0.001),":[322],"followed":[323],"6.07,":[329],"0.036),":[331],"65":[335],"4.06,":[337],"0.012),":[339],"2.68,":[344],"0.046),":[346],"BMI":[348],"1.09,":[350],"0.008).":[352,376],"presence":[354],"decreased":[362],"likelihood":[363],"0.24,":[367],"0.013),":[369],"CKD":[372],"0.17,":[374],"Conclusions:":[377],"index,":[397],"disease,":[409],"valuable":[420],"tool":[421],"discriminating":[423],"between":[424],"among":[428],"pain.":[439],"This":[440],"preliminary":[441],"analysis":[442],"provides":[443],"foundation":[445],"larger":[447],"prospective":[449],"studies":[450],"validation.":[452],"Application":[453],"this":[455],"along":[458],"other":[460],"clinical":[461],"factors,":[462],"may":[463],"reduce":[464],"number":[466],"potentially":[468],"avoidable":[469],"admissions":[470],"costs.":[473]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2016-06-24T00:00:00"}