{"id":"https://openalex.org/W2175771867","doi":"https://doi.org/10.1152/ajpgi.1988.254.2.g249","title":"Human pancreatic secretion during phase II antral motility of the interdigestive cycle","display_name":"Human pancreatic secretion during phase II antral motility of the interdigestive cycle","publication_year":1988,"publication_date":"1988-02-01","ids":{"openalex":"https://openalex.org/W2175771867","doi":"https://doi.org/10.1152/ajpgi.1988.254.2.g249","mag":"2175771867","pmid":"https://pubmed.ncbi.nlm.nih.gov/3348376"},"language":"en","primary_location":{"id":"doi:10.1152/ajpgi.1988.254.2.g249","doi":"https://doi.org/10.1152/ajpgi.1988.254.2.g249","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpgi.1988.254.2.g249","pdf_url":null,"source":{"id":"https://openalex.org/S34136372","display_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","issn_l":"0193-1857","issn":["0193-1857","1522-1547"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065400172","display_name":"Peter Layer","orcid":"https://orcid.org/0000-0003-2829-201X","observed_orcids":["https://orcid.org/0000-0003-2829-201X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. Layer","raw_affiliation_strings":["Division of Gastroenterology, Mayo Clinic and Foundation, Rochester,Minnesota 55905"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Mayo Clinic and Foundation, Rochester,Minnesota 55905","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104335548","display_name":"A. T. Chan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. T. Chan","raw_affiliation_strings":["Division of Gastroenterology, Mayo Clinic and Foundation, Rochester,Minnesota 55905"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Mayo Clinic and Foundation, Rochester,Minnesota 55905","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109087336","display_name":"V. L. W. Go","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"V. L. Go","raw_affiliation_strings":["Division of Gastroenterology, Mayo Clinic and Foundation, Rochester,Minnesota 55905"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Mayo Clinic and Foundation, Rochester,Minnesota 55905","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035521528","display_name":"Eugene P. DiMagno","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E. P. DiMagno","raw_affiliation_strings":["Division of Gastroenterology, Mayo Clinic and Foundation, Rochester,Minnesota 55905"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Mayo Clinic and Foundation, Rochester,Minnesota 55905","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":null,"apc_paid":null,"fwci":3.7658,"has_fulltext":false,"cited_by_count":59,"citation_normalized_percentile":{"value":0.93273175,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"254","issue":"2","first_page":"G249","last_page":"G253"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13199","display_name":"Digestive system and related health","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pancreatic-secretion","display_name":"pancreatic secretion","score":0.8889999985694885},{"id":"https://openalex.org/keywords/duodenal-motility","display_name":"duodenal motility","score":0.8650000095367432},{"id":"https://openalex.org/keywords/motilin","display_name":"motilin","score":0.875},{"id":"https://openalex.org/keywords/fasting","display_name":"fasting","score":0.7730000019073486}],"concepts":[{"id":"https://openalex.org/C58207958","wikidata":"https://www.wikidata.org/wiki/Q33596","display_name":"Motility","level":2,"score":0.8464412689208984},{"id":"https://openalex.org/C131793682","wikidata":"https://www.wikidata.org/wiki/Q126440","display_name":"Motilin","level":2,"score":0.842963695526123},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7999353408813477},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7024886012077332},{"id":"https://openalex.org/C131253125","wikidata":"https://www.wikidata.org/wiki/Q609361","display_name":"Antrum","level":3,"score":0.6423479318618774},{"id":"https://openalex.org/C35147842","wikidata":"https://www.wikidata.org/wiki/Q3539520","display_name":"Migrating motor complex","level":3,"score":0.5379612445831299},{"id":"https://openalex.org/C22885893","wikidata":"https://www.wikidata.org/wiki/Q4862743","display_name":"Cholinergic","level":2,"score":0.5036792159080505},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.49929237365722656},{"id":"https://openalex.org/C2778108375","wikidata":"https://www.wikidata.org/wiki/Q246978","display_name":"Pancreatic polypeptide","level":4,"score":0.46715205907821655},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46634477376937866},{"id":"https://openalex.org/C2780340462","wikidata":"https://www.wikidata.org/wiki/Q127450","display_name":"Trypsin","level":3,"score":0.4390358030796051},{"id":"https://openalex.org/C176685330","wikidata":"https://www.wikidata.org/wiki/Q857638","display_name":"Radioimmunoassay","level":2,"score":0.42572206258773804},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3539479374885559},{"id":"https://openalex.org/C2777882243","wikidata":"https://www.wikidata.org/wiki/Q11090","display_name":"Small intestine","level":2,"score":0.31724613904953003},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.20862463116645813},{"id":"https://openalex.org/C2779422922","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"Stomach","level":2,"score":0.15880000591278076},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.1574004888534546},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09972310066223145},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.09106099605560303},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.04964938759803772},{"id":"https://openalex.org/C2778563252","wikidata":"https://www.wikidata.org/wiki/Q170617","display_name":"Glucagon","level":3,"score":0.046011775732040405}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004063","descriptor_name":"Digestion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004386","descriptor_name":"Duodenum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005769","descriptor_name":"Gastrointestinal Motility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009037","descriptor_name":"Motilin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010179","descriptor_name":"Pancreas","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010191","descriptor_name":"Pancreatic Polypeptide","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011706","descriptor_name":"Pyloric Antrum","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1152/ajpgi.1988.254.2.g249","doi":"https://doi.org/10.1152/ajpgi.1988.254.2.g249","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpgi.1988.254.2.g249","pdf_url":null,"source":{"id":"https://openalex.org/S34136372","display_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","issn_l":"0193-1857","issn":["0193-1857","1522-1547"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Gastrointestinal and Liver Physiology","raw_type":"journal-article"},{"id":"pmid:3348376","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3348376","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of physiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1533119110","display_name":null,"funder_award_id":"RR-585","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"}],"funders":[{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2057371658","https://openalex.org/W1979517520","https://openalex.org/W1982132664","https://openalex.org/W2102035786","https://openalex.org/W1540312478","https://openalex.org/W2003034238","https://openalex.org/W2410932623","https://openalex.org/W2326889965","https://openalex.org/W2047404973","https://openalex.org/W7097296531"],"abstract_inverted_index":{"We":[0],"determined":[1],"if":[2],"changes":[3],"in":[4,16,24,182],"the":[5,12,29,133,149,183],"irregular":[6],"motor":[7,97],"activity":[8,57],"of":[9,33,67,78,87,110,135,145,151],"phase":[10,15,55,95,136,152,173,188],"II,":[11],"dominant":[13],"motility":[14,42,52,138,154,191],"awake":[17],"fasting":[18],"humans,":[19],"are":[20,180],"associated":[21,101],"with":[22,102,132],"fluctuations":[23],"pancreatic":[25,82,167,193],"secretion":[26],"by":[27],"intubating":[28],"upper":[30],"gastrointestinal":[31],"tract":[32],"15":[34],"healthy":[35],"humans":[36],"and":[37,40,43,69,75,80,93,117,148,169,192],"recording":[38],"antral":[39],"duodenal":[41,45,72],"obtaining":[44],"samples":[46],"for":[47],"one":[48],"or":[49,64],"two":[50],"interdigestive":[51,190],"cycles.":[53],"Antral":[54],"II":[56,96,137,153,174,189],"was":[58],"graded":[59],"as":[60],"having":[61],"low,":[62],"intermediate,":[63,92],"high":[65,94],"frequency":[66],"contractions":[68],"related":[70],"to":[71],"trypsin":[73,103],"output":[74],"plasma":[76,146,170],"concentrations":[77],"motilin":[79,127],"human":[81],"polypeptide":[83],"(HPP),":[84],"a":[85],"marker":[86],"vagal":[88,177],"cholinergic":[89,178],"tone.":[90],"Low,":[91],"activities":[98],"were":[99,155],"significantly":[100],"outputs":[104],"(U/10":[105],"min;":[106],"mean":[107],"+/-":[108,112,115,119],"SE)":[109],"576":[111],"137,":[113],"1,441":[114],"225,":[116],"3,621":[118],"521,":[120],"respectively":[121],"(P":[122,139,158],"less":[123,159],"than":[124,141,160],"0.001).":[125,161],"Plasma":[126],"levels":[128,144],"did":[129],"not":[130],"vary":[131],"grades":[134,150],"greater":[140],"0.1),":[142],"but":[143],"HPP":[147,171],"positively":[156],"correlated":[157],"The":[162],"close":[163],"correlation":[164],"among":[165],"motility,":[166],"secretion,":[168],"during":[172],"suggests":[175],"that":[176],"pathways":[179],"involved":[181],"common":[184],"regulatory":[185],"mechanism":[186],"controlling":[187],"secretion.":[194]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}