{"id":"https://openalex.org/W2175497939","doi":"https://doi.org/10.1002/jhet.5570410417","title":"4\u2010hydroxy\u20106\u2010methyl\u20103\u2010(5\u2010phenyl\u20102E,4E\u2010pentadien\u20101\u2010oyl)\u20102H\u2010pyran\u20102\u2010one: Synthesis and reactivity with amines","display_name":"4\u2010hydroxy\u20106\u2010methyl\u20103\u2010(5\u2010phenyl\u20102E,4E\u2010pentadien\u20101\u2010oyl)\u20102H\u2010pyran\u20102\u2010one: Synthesis and reactivity with amines","publication_year":2004,"publication_date":"2004-07-01","ids":{"openalex":"https://openalex.org/W2175497939","doi":"https://doi.org/10.1002/jhet.5570410417","mag":"2175497939"},"language":"en","primary_location":{"id":"doi:10.1002/jhet.5570410417","doi":"https://doi.org/10.1002/jhet.5570410417","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jhet.5570410417","pdf_url":null,"source":{"id":"https://openalex.org/S46134040","display_name":"Journal of Heterocyclic Chemistry","issn_l":"0022-152X","issn":["0022-152X","1943-5193"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Heterocyclic Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071085560","display_name":"Nabila A\u00eft\u2010Baziz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157169809","display_name":"University of Sciences and Technology Houari Boumediene","ror":"https://ror.org/02kb89c09","country_code":"DZ","type":"education","lineage":["https://openalex.org/I157169809"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Nabila A\u00eft\u2010Baziz","raw_affiliation_strings":["Laboratoire des Compose\u0301s Organiques He\u0301te\u0301rocycliques, Faculte\u0301 de Chimie, Universite\u0301 des Sciences et de la Technologie H. Boumedie\u0300ne, BP 32 El-Alia, 16111 Bab-Ezzouar, Alger, Alge\u0301rie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire des Compose\u0301s Organiques He\u0301te\u0301rocycliques, Faculte\u0301 de Chimie, Universite\u0301 des Sciences et de la Technologie H. Boumedie\u0300ne, BP 32 El-Alia, 16111 Bab-Ezzouar, Alger, Alge\u0301rie","institution_ids":["https://openalex.org/I157169809"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054892975","display_name":"Yah\u00efa Rachedi","orcid":"https://orcid.org/0000-0003-1766-2089","observed_orcids":["https://orcid.org/0000-0003-1766-2089"]},"institutions":[{"id":"https://openalex.org/I157169809","display_name":"University of Sciences and Technology Houari Boumediene","ror":"https://ror.org/02kb89c09","country_code":"DZ","type":"education","lineage":["https://openalex.org/I157169809"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Yahia Rachedi","raw_affiliation_strings":["Laboratoire des Compose\u0301s Organiques He\u0301te\u0301rocycliques, Faculte\u0301 de Chimie, Universite\u0301 des Sciences et de la Technologie H. Boumedie\u0300ne, BP 32 El-Alia, 16111 Bab-Ezzouar, Alger, Alge\u0301rie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire des Compose\u0301s Organiques He\u0301te\u0301rocycliques, Faculte\u0301 de Chimie, Universite\u0301 des Sciences et de la Technologie H. Boumedie\u0300ne, BP 32 El-Alia, 16111 Bab-Ezzouar, Alger, Alge\u0301rie","institution_ids":["https://openalex.org/I157169809"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033851218","display_name":"Maamer Hamdi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157169809","display_name":"University of Sciences and Technology Houari Boumediene","ror":"https://ror.org/02kb89c09","country_code":"DZ","type":"education","lineage":["https://openalex.org/I157169809"]}],"countries":["DZ"],"is_corresponding":true,"raw_author_name":"Maamer Hamdi","raw_affiliation_strings":["Laboratoire des Compose\u0301s Organiques He\u0301te\u0301rocycliques, Faculte\u0301 de Chimie, Universite\u0301 des Sciences et de la Technologie H. Boumedie\u0300ne, BP 32 El-Alia, 16111 Bab-Ezzouar, Alger, Alge\u0301rie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire des Compose\u0301s Organiques He\u0301te\u0301rocycliques, Faculte\u0301 de Chimie, Universite\u0301 des Sciences et de la Technologie H. Boumedie\u0300ne, BP 32 El-Alia, 16111 Bab-Ezzouar, Alger, Alge\u0301rie","institution_ids":["https://openalex.org/I157169809"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100635121","display_name":"Artur M. S. Silva","orcid":"https://orcid.org/0000-0003-2861-8286","observed_orcids":["https://orcid.org/0000-0003-2861-8286"]},"institutions":[{"id":"https://openalex.org/I60858718","display_name":"University of Aveiro","ror":"https://ror.org/00nt41z93","country_code":"PT","type":"education","lineage":["https://openalex.org/I60858718"]}],"countries":["PT"],"is_corresponding":true,"raw_author_name":"Artur M. S. Silva","raw_affiliation_strings":["Department of Chemistry, University of Aveiro, 3810\u2013193, Aveiro, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Aveiro, 3810\u2013193, Aveiro, Portugal","institution_ids":["https://openalex.org/I60858718"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086016178","display_name":"Fadila Balegroune","orcid":"https://orcid.org/0000-0001-9335-4067","observed_orcids":["https://orcid.org/0000-0001-9335-4067"]},"institutions":[{"id":"https://openalex.org/I157169809","display_name":"University of Sciences and Technology Houari Boumediene","ror":"https://ror.org/02kb89c09","country_code":"DZ","type":"education","lineage":["https://openalex.org/I157169809"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"F. Balegroune","raw_affiliation_strings":["Laboratoire de Cristalloraphie-Thermodynamique, Faculte\u0301 de Chimie, USTHB, BP 32 El-Alia, 16111 Bab-Ezzouar, Alger, Alge\u0301rie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Cristalloraphie-Thermodynamique, Faculte\u0301 de Chimie, USTHB, BP 32 El-Alia, 16111 Bab-Ezzouar, Alger, Alge\u0301rie","institution_ids":["https://openalex.org/I157169809"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049143428","display_name":"Thierry Roisnel","orcid":"https://orcid.org/0000-0002-6088-4472","observed_orcids":["https://orcid.org/0000-0002-6088-4472"]},"institutions":[{"id":"https://openalex.org/I4405258264","display_name":"Universit\u00e9 Rennes 1","ror":"https://ror.org/00crteh33","country_code":"FR","type":"education","lineage":["https://openalex.org/I4405258264","https://openalex.org/I56067802"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Roisnel Thierry","raw_affiliation_strings":["Centre de Diffractometrie, Universite\u0301 de Rennes I, Campus de Baulieu, 35042 Rennes Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Diffractometrie, Universite\u0301 de Rennes I, Campus de Baulieu, 35042 Rennes Cedex, France","institution_ids":["https://openalex.org/I4405258264"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020682435","display_name":"Nicole M. Sellier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149758196","display_name":"Chimie ParisTech - PSL","ror":"https://ror.org/05q65zh81","country_code":"FR","type":"education","lineage":["https://openalex.org/I149758196","https://openalex.org/I190752583"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"N. Sellier","raw_affiliation_strings":["Lab. de Spectrome\u0301trie de Masse (URM 75\u201373), ENSCP, 11 Rue Pierre et Marie Curie, 75231 Paris, Ce\u0301dex 05, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. de Spectrome\u0301trie de Masse (URM 75\u201373), ENSCP, 11 Rue Pierre et Marie Curie, 75231 Paris, Ce\u0301dex 05, France","institution_ids":["https://openalex.org/I149758196"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5020682435","https://openalex.org/A5033851218","https://openalex.org/A5049143428","https://openalex.org/A5100635121"],"corresponding_institution_ids":["https://openalex.org/I149758196","https://openalex.org/I157169809","https://openalex.org/I4405258264","https://openalex.org/I60858718"],"apc_list":{"value":3400,"currency":"USD","value_usd":3400},"apc_paid":null,"fwci":0.8095,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.64716993,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"41","issue":"4","first_page":"587","last_page":"591"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13876","display_name":"Chemical synthesis and pharmacological studies","score":0.6894999742507935,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13876","display_name":"Chemical synthesis and pharmacological studies","score":0.6894999742507935,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13208","display_name":"Synthesis of heterocyclic compounds","score":0.10279999673366547,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13023","display_name":"Synthesis of Organic Compounds","score":0.06949999928474426,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amine-reactivity","display_name":"amine reactivity","score":0.5730000138282776},{"id":"https://openalex.org/keywords/hydrazine-derivatives","display_name":"hydrazine derivatives","score":0.8769999742507935},{"id":"https://openalex.org/keywords/pyrazole-formation","display_name":"pyrazole formation","score":0.7730000019073486},{"id":"https://openalex.org/keywords/o-phenylenediamine","display_name":"o-phenylenediamine","score":0.9629999995231628},{"id":"https://openalex.org/keywords/1-5-benzodiazepines","display_name":"1,5-benzodiazepines","score":0.9710000157356262},{"id":"https://openalex.org/keywords/ethylamine","display_name":"ethylamine","score":0.8740000128746033},{"id":"https://openalex.org/keywords/ring-opening","display_name":"ring opening","score":0.9179999828338623},{"id":"https://openalex.org/keywords/pi-conjugated-molecules","display_name":"conjugated molecules","score":0.6759999990463257},{"id":"https://openalex.org/keywords/nucleophilic-addition","display_name":"nucleophilic addition","score":0.6420000195503235}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9673486948013306},{"id":"https://openalex.org/C2777505907","wikidata":"https://www.wikidata.org/wiki/Q217356","display_name":"Pyran","level":2,"score":0.8673262000083923},{"id":"https://openalex.org/C2776910235","wikidata":"https://www.wikidata.org/wiki/Q18574","display_name":"Reactivity (psychology)","level":3,"score":0.7988690137863159},{"id":"https://openalex.org/C178907741","wikidata":"https://www.wikidata.org/wiki/Q745930","display_name":"Nucleophile","level":3,"score":0.6638513803482056},{"id":"https://openalex.org/C2778678469","wikidata":"https://www.wikidata.org/wiki/Q411119","display_name":"Ethylamine","level":2,"score":0.662057101726532},{"id":"https://openalex.org/C2776597398","wikidata":"https://www.wikidata.org/wiki/Q5954496","display_name":"Hydrazine (antidepressant)","level":2,"score":0.5234555602073669},{"id":"https://openalex.org/C112613896","wikidata":"https://www.wikidata.org/wiki/Q898370","display_name":"Conjugated system","level":3,"score":0.5166971683502197},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.46642810106277466},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.4624486267566681},{"id":"https://openalex.org/C2780378348","wikidata":"https://www.wikidata.org/wiki/Q25351438","display_name":"Ring (chemistry)","level":2,"score":0.41508522629737854},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.3289061188697815},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.09596437215805054},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.045618534088134766},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/jhet.5570410417","doi":"https://doi.org/10.1002/jhet.5570410417","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jhet.5570410417","pdf_url":null,"source":{"id":"https://openalex.org/S46134040","display_name":"Journal of Heterocyclic Chemistry","issn_l":"0022-152X","issn":["0022-152X","1943-5193"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Heterocyclic Chemistry","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":4,"referenced_works":["https://openalex.org/W2055406244","https://openalex.org/W2062326891","https://openalex.org/W2067901924","https://openalex.org/W2332665642"],"related_works":["https://openalex.org/W2950410793","https://openalex.org/W2017023013","https://openalex.org/W2044557489","https://openalex.org/W2108537526","https://openalex.org/W2951974277","https://openalex.org/W1983833059","https://openalex.org/W1973139565","https://openalex.org/W2949366946","https://openalex.org/W2145300416","https://openalex.org/W2026036793"],"abstract_inverted_index":{"Abstract":[0],"The":[1,31],"synthesis":[2],"and":[3,42],"reactivity":[4],"studies":[5],"of":[6,14,33,45],"4\u2010hydroxy\u20106\u2010methyl\u20103\u2010(5\u2010phenyl\u20102E,4E\u2010pentadien\u20101\u2010oyl)\u20102H\u2010pyran\u20102\u2010one":[7],"2":[8,15,34],"with":[9,16,27,35],"nucleophiles":[10],"are":[11],"reported.":[12],"Reactions":[13],"hydrazine":[17],"derivatives":[18],"gave":[19],"new":[20],"pyrazole\u2010type":[21],"com":[22],"pounds":[23],"while":[24],"the":[25,38,43],"reaction":[26,32],"ortho\u2010phenylenediamines":[28],"yielded":[29],"1,5\u2010benzodiazepines.":[30],"ethylamine":[36],"implies":[37],"2H\u2010pyran\u20102\u2010one":[39],"ring":[40],"opening":[41],"formation":[44],"a":[46],"strong":[47],"conjugated":[48],"compound":[49],"3.":[50]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}