{"id":"https://openalex.org/W2175462631","doi":"https://doi.org/10.1186/s40064-015-1485-6","title":"The role of chemotherapy and operation on lymphocytes accumulation in peripheral blood obtained from patients with oral squamous cell carcinoma","display_name":"The role of chemotherapy and operation on lymphocytes accumulation in peripheral blood obtained from patients with oral squamous cell carcinoma","publication_year":2015,"publication_date":"2015-11-12","ids":{"openalex":"https://openalex.org/W2175462631","doi":"https://doi.org/10.1186/s40064-015-1485-6","mag":"2175462631","pmid":"https://pubmed.ncbi.nlm.nih.gov/26587366","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4643067"},"language":"en","primary_location":{"id":"doi:10.1186/s40064-015-1485-6","doi":"https://doi.org/10.1186/s40064-015-1485-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s40064-015-1485-6","pdf_url":"https://springerplus.springeropen.com/counter/pdf/10.1186/s40064-015-1485-6","source":{"id":"https://openalex.org/S2531072874","display_name":"SpringerPlus","issn_l":"2193-1801","issn":["2193-1801"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310319972","host_organization_name":"Springer International Publishing","host_organization_lineage":["https://openalex.org/P4310319972","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer International Publishing","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SpringerPlus","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://springerplus.springeropen.com/counter/pdf/10.1186/s40064-015-1485-6","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039504311","display_name":"Yu Tao","orcid":"https://orcid.org/0000-0001-5087-7474","observed_orcids":["https://orcid.org/0000-0001-5087-7474"]},"institutions":[{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Tao Yu","raw_affiliation_strings":["Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina","institution_ids":["https://openalex.org/I4210118556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100638838","display_name":"Ping Guo","orcid":"https://orcid.org/0000-0003-0096-4814","observed_orcids":["https://orcid.org/0000-0003-0096-4814"]},"institutions":[{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ping Guo","raw_affiliation_strings":["Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina","institution_ids":["https://openalex.org/I4210118556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045724389","display_name":"Yingying Wu","orcid":"https://orcid.org/0000-0002-3717-8350","observed_orcids":["https://orcid.org/0000-0002-3717-8350","https://orcid.org/0009-0004-2493-3718"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4391768043","display_name":"State Key Laboratory of Oral Diseases","ror":"https://ror.org/00pvqk557","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24185976","https://openalex.org/I4391768043"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yingying Wu","raw_affiliation_strings":["State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, People's Republic Ofchina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, People's Republic Ofchina","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4391768043"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033431809","display_name":"Jiafeng Zhao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiafeng Zhao","raw_affiliation_strings":["Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina","institution_ids":["https://openalex.org/I4210118556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100929320","display_name":"Lichun Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lichun Wu","raw_affiliation_strings":["Department of Clinical Laboratory, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Laboratory, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina","institution_ids":["https://openalex.org/I4210118556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100781352","display_name":"Chunhua Li","orcid":"https://orcid.org/0000-0002-0895-3506","observed_orcids":["https://orcid.org/0000-0002-0895-3506"]},"institutions":[{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunhua Li","raw_affiliation_strings":["Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina","institution_ids":["https://openalex.org/I4210118556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100683528","display_name":"Kun Liu","orcid":"https://orcid.org/0009-0008-5976-3009","observed_orcids":["https://orcid.org/0009-0008-5976-3009"]},"institutions":[{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kun Liu","raw_affiliation_strings":["Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina","institution_ids":["https://openalex.org/I4210118556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000700564","display_name":"Guiquan Zhu","orcid":"https://orcid.org/0000-0002-8316-5809","observed_orcids":["https://orcid.org/0000-0002-8316-5809"]},"institutions":[{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guiquan Zhu","raw_affiliation_strings":["Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina","institution_ids":["https://openalex.org/I4210118556"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jin Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jin Chen","raw_affiliation_strings":["Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina","institution_ids":["https://openalex.org/I4210118556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076360056","display_name":"Chuan Shan Xu","orcid":"https://orcid.org/0000-0002-5320-2277","observed_orcids":["https://orcid.org/0000-0002-5320-2277"]},"institutions":[{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chuan Xu","raw_affiliation_strings":["Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina","institution_ids":["https://openalex.org/I4210118556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068991651","display_name":"Yongcong Cai","orcid":"https://orcid.org/0000-0001-6717-8055","observed_orcids":["https://orcid.org/0000-0001-6717-8055"]},"institutions":[{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yongcong Cai","raw_affiliation_strings":["Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina","institution_ids":["https://openalex.org/I4210118556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101927980","display_name":"Jifeng Liu","orcid":"https://orcid.org/0000-0002-7673-8461","observed_orcids":["https://orcid.org/0000-0002-7673-8461"]},"institutions":[{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jifeng Liu","raw_affiliation_strings":["Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina","institution_ids":["https://openalex.org/I4210118556"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100358060","display_name":"Zhaohui Wang","orcid":"https://orcid.org/0000-0003-4357-9780","observed_orcids":["https://orcid.org/0000-0003-4357-9780"]},"institutions":[{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhaohui Wang","raw_affiliation_strings":["Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No.55, Sec.4, Renminnan Road, Chengdu, 610041, Sichuan, People's Republic Ofchina","institution_ids":["https://openalex.org/I4210118556"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5039504311","https://openalex.org/A5100358060"],"corresponding_institution_ids":["https://openalex.org/I4210118556"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.106111,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"4","issue":"1","first_page":"698","last_page":"698"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.5580999851226807,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.5580999851226807,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.39989998936653137,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.020400000736117363,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oral-squamous-cell-carcinoma","display_name":"oral squamous cell carcinoma","score":1.0},{"id":"https://openalex.org/keywords/cancer-immunoediting","display_name":"cancer immunoediting","score":0.7670000195503235},{"id":"https://openalex.org/keywords/peripheral-blood-lymphocytes","display_name":"peripheral blood lymphocytes","score":0.7329999804496765},{"id":"https://openalex.org/keywords/cd4-t-cells","display_name":"CD4+ T cells","score":0.9860000014305115},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":1.0},{"id":"https://openalex.org/keywords/b-cells","display_name":"B cells","score":0.9350000023841858},{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.9869999885559082},{"id":"https://openalex.org/keywords/chemotherapy","display_name":"chemotherapy","score":0.6570000052452087},{"id":"https://openalex.org/keywords/radical-surgery","display_name":"radical surgery","score":0.9279999732971191},{"id":"https://openalex.org/keywords/tp-regimen","display_name":"TP regimen","score":0.5419999957084656},{"id":"https://openalex.org/keywords/tnm-staging","display_name":"TNM staging","score":0.7519999742507935},{"id":"https://openalex.org/keywords/lymph-node-metastasis","display_name":"lymph node metastasis","score":0.925000011920929},{"id":"https://openalex.org/keywords/antitumor-immunity","display_name":"antitumor immunity","score":0.8059999942779541}],"concepts":[{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.5793004631996155},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.551672101020813},{"id":"https://openalex.org/C2778957590","wikidata":"https://www.wikidata.org/wiki/Q798033","display_name":"CD19","level":3,"score":0.5482032299041748},{"id":"https://openalex.org/C114684123","wikidata":"https://www.wikidata.org/wiki/Q419458","display_name":"CD3","level":4,"score":0.4878964126110077},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4540473222732544},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.45236486196517944},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.45164912939071655},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.4162448048591614},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.38668903708457947},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.36123690009117126},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3403492271900177},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3312942683696747}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1186/s40064-015-1485-6","doi":"https://doi.org/10.1186/s40064-015-1485-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s40064-015-1485-6","pdf_url":"https://springerplus.springeropen.com/counter/pdf/10.1186/s40064-015-1485-6","source":{"id":"https://openalex.org/S2531072874","display_name":"SpringerPlus","issn_l":"2193-1801","issn":["2193-1801"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310319972","host_organization_name":"Springer International Publishing","host_organization_lineage":["https://openalex.org/P4310319972","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer International Publishing","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SpringerPlus","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3621273","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4643067","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4643067","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4643067","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Springerplus","raw_type":"Text"},{"id":"pmid:26587366","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26587366","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SpringerPlus","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1186/s40064-015-1485-6","doi":"https://doi.org/10.1186/s40064-015-1485-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s40064-015-1485-6","pdf_url":"https://springerplus.springeropen.com/counter/pdf/10.1186/s40064-015-1485-6","source":{"id":"https://openalex.org/S2531072874","display_name":"SpringerPlus","issn_l":"2193-1801","issn":["2193-1801"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310319972","host_organization_name":"Springer International Publishing","host_organization_lineage":["https://openalex.org/P4310319972","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer International Publishing","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SpringerPlus","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320322922","display_name":"Department of Science and Technology of Sichuan Province","ror":"https://ror.org/04323m874"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2175462631.pdf","grobid_xml":"https://content.openalex.org/works/W2175462631.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W1493822493","https://openalex.org/W1546896134","https://openalex.org/W1950287009","https://openalex.org/W1963768706","https://openalex.org/W1977955576","https://openalex.org/W1979505520","https://openalex.org/W1989133830","https://openalex.org/W2004630197","https://openalex.org/W2007990687","https://openalex.org/W2015090245","https://openalex.org/W2019214729","https://openalex.org/W2020720650","https://openalex.org/W2028186534","https://openalex.org/W2061450798","https://openalex.org/W2063882298","https://openalex.org/W2067096807","https://openalex.org/W2085295950","https://openalex.org/W2107388582","https://openalex.org/W2110318199","https://openalex.org/W2114185671","https://openalex.org/W2114360891","https://openalex.org/W2117803310","https://openalex.org/W2131671889","https://openalex.org/W2132509553","https://openalex.org/W2134244017","https://openalex.org/W2137018390","https://openalex.org/W2143522754","https://openalex.org/W2145761792","https://openalex.org/W2168042181","https://openalex.org/W2171448135"],"related_works":["https://openalex.org/W4211102345","https://openalex.org/W4388946102","https://openalex.org/W2158909206","https://openalex.org/W3006952170","https://openalex.org/W4394998462","https://openalex.org/W2189424736","https://openalex.org/W2914352966","https://openalex.org/W2401738289","https://openalex.org/W4385321292","https://openalex.org/W3211656051"],"abstract_inverted_index":{"The":[0,98,125,164],"\"Cancer":[1],"Immunoediting\"":[2],"concept":[3],"has":[4],"provided":[5],"critical":[6],"insights":[7,198],"suggesting":[8],"dual":[9],"functions":[10],"of":[11,25,52,76,100,127,147,166,203,222],"immune":[12],"system":[13],"during":[14,46],"the":[15,21,39,145,201,220],"cancer":[16,205],"initiation":[17],"and":[18,23,27,34,72,88,92,95,114,141,161,193,213],"development.":[19],"However,":[20],"dynamics":[22],"roles":[24,189],"CD4(+)":[26,184],"CD8(+)":[28],"T":[29,80,83,102,129,149,185],"cells,":[30,33,81,84],"CD19(+)":[31],"B":[32,86,169],"CD56(+)":[35],"NK":[36,90],"cells":[37,87,91,103,130,150,170,186],"in":[38,107,122,134,154,176,190],"patients":[40,54,136,156,177,226],"with":[41,55,78,173,178,227],"oral":[42],"squamous":[43],"cell":[44],"carcinoma":[45],"treatment":[47],"remain":[48],"unclear.":[49],"A":[50],"total":[51],"43":[53],"OSCC":[56,135,155,191],"were":[57,104,131,151],"divided":[58],"into":[59],"different":[60,64,93],"groups":[61],"according":[62],"to":[63,120,218],"clinical":[65],"factors":[66],"(TNM":[67],"staging,":[68],"pathological":[69],"patterns,":[70],"age":[71],"genders)":[73],"for":[74,200],"assessment":[75],"relations":[77],"CD3(+)CD4(+)":[79,101,128],"CD3(+)CD8(+)":[82,148],"CD3(-)CD19(+)":[85,168],"CD3(-)CD16(+)CD56(+)":[89],"chemotherapy":[94,212],"radical":[96,142,162,174,214],"operation.":[97,143,163],"expression":[99],"significantly":[105,132,152],"increased":[106,133],"advanced":[108],"tumor":[109,112],"stage,":[110],"large":[111],"size":[113],"positive":[115],"lymph":[116],"nodes":[117],"metastasis,":[118],"compared":[119],"that":[121,183],"early":[123],"groups.":[124],"accumulation":[126,146],"received":[137,157],"2":[138,158,208],"cycles":[139,159,209],"CT":[140,160],"Moreover,":[144],"decreased":[153],"distribution":[165],"circulating":[167],"was":[171],"related":[172],"operation":[175],"OSCC.":[179,228],"This":[180],"study":[181],"indicate":[182],"have":[187],"opposing":[188],"progression":[192],"outcomes,":[194],"which":[195],"provides":[196],"new":[197],"relevant":[199],"development":[202],"effective":[204],"immunotherapeutic":[206],"approaches.":[207],"TP":[210],"regime":[211],"therapy":[215],"may":[216],"contribute":[217],"increase":[219],"effects":[221],"anti-tumor":[223],"immunity":[224],"on":[225]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}