{"id":"https://openalex.org/W2175125998","doi":"https://doi.org/10.1371/journal.pmed.1001900","title":"Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa","display_name":"Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa","publication_year":2015,"publication_date":"2015-11-17","ids":{"openalex":"https://openalex.org/W2175125998","doi":"https://doi.org/10.1371/journal.pmed.1001900","mag":"2175125998","pmid":"https://pubmed.ncbi.nlm.nih.gov/26575988","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4648589"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pmed.1001900","doi":"https://doi.org/10.1371/journal.pmed.1001900","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pmed.1001900","pdf_url":"https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1001900&type=printable","source":{"id":"https://openalex.org/S197939330","display_name":"PLoS Medicine","issn_l":"1549-1277","issn":["1549-1277","1549-1676"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1001900&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071551266","display_name":"Angelique H\u00f6lzemer","orcid":"https://orcid.org/0000-0002-1446-3474","observed_orcids":["https://orcid.org/0000-0002-1446-3474"]},"institutions":[{"id":"https://openalex.org/I137251492","display_name":"Leibniz Institute of Virology (LIV)","ror":"https://ror.org/02r2q1d96","country_code":"DE","type":"facility","lineage":["https://openalex.org/I137251492","https://openalex.org/I315704651"]},{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Angelique H\u00f6lzemer","raw_affiliation_strings":["First Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany","Heinrich-Pette-Institut, Leibniz Institute for Experimental Virology, Hamburg, Germany","Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Heinrich-Pette-Institut, Leibniz Institute for Experimental Virology, Hamburg, Germany","institution_ids":["https://openalex.org/I137251492"]},{"raw_affiliation_string":"Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America","institution_ids":["https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081656476","display_name":"Christina Thobakgale","orcid":"https://orcid.org/0000-0001-5619-8894","observed_orcids":["https://orcid.org/0000-0001-5619-8894"]},"institutions":[{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]},{"id":"https://openalex.org/I95023434","display_name":"University of KwaZulu-Natal","ror":"https://ror.org/04qzfn040","country_code":"ZA","type":"education","lineage":["https://openalex.org/I95023434"]}],"countries":["US","ZA"],"is_corresponding":false,"raw_author_name":"Christina F. Thobakgale","raw_affiliation_strings":["HIV Pathogenesis Programme, Doris Duke Medical Research Institute, KwaZulu-Natal Research Institute for Tuberculosis and HIV, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa","Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HIV Pathogenesis Programme, Doris Duke Medical Research Institute, KwaZulu-Natal Research Institute for Tuberculosis and HIV, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa","institution_ids":["https://openalex.org/I95023434"]},{"raw_affiliation_string":"Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America","institution_ids":["https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108546506","display_name":"Camilo Andr\u00e9s Jim\u00e9nez Cruz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114115","display_name":"IBM Research - Thomas J. Watson Research Center","ror":"https://ror.org/0265w5591","country_code":"US","type":"facility","lineage":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Camilo A. Jimenez Cruz","raw_affiliation_strings":["Computational Biology Center, IBM Thomas J. Watson Research Center, Yorktown Heights, New York, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Biology Center, IBM Thomas J. Watson Research Center, Yorktown Heights, New York, United States of America","institution_ids":["https://openalex.org/I4210114115"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046584692","display_name":"Wilfredo F. Garc\u00eda-Beltr\u00e1n","orcid":"https://orcid.org/0000-0002-7109-0504","observed_orcids":["https://orcid.org/0000-0002-7109-0504"]},"institutions":[{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wilfredo F. Garcia-Beltran","raw_affiliation_strings":["Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America","institution_ids":["https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036943948","display_name":"Jonathan M. Carlson","orcid":"https://orcid.org/0000-0001-6618-3653","observed_orcids":["https://orcid.org/0000-0001-6618-3653"]},"institutions":[{"id":"https://openalex.org/I1290206253","display_name":"Microsoft (United States)","ror":"https://ror.org/00d0nc645","country_code":"US","type":"company","lineage":["https://openalex.org/I1290206253"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan M. Carlson","raw_affiliation_strings":["Microsoft Research, Los Angeles, California, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microsoft Research, Los Angeles, California, United States of America","institution_ids":["https://openalex.org/I1290206253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010330292","display_name":"Nienke H. van Teijlingen","orcid":"https://orcid.org/0000-0002-5693-1619","observed_orcids":["https://orcid.org/0000-0002-5693-1619"]},"institutions":[{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Nienke H. van Teijlingen","raw_affiliation_strings":["Experimental Immunology, Academic Medical Center, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Immunology, Academic Medical Center, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2802928900"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044055108","display_name":"Jaclyn Kelly Mann","orcid":"https://orcid.org/0000-0002-2398-1273","observed_orcids":["https://orcid.org/0000-0002-2398-1273"]},"institutions":[{"id":"https://openalex.org/I95023434","display_name":"University of KwaZulu-Natal","ror":"https://ror.org/04qzfn040","country_code":"ZA","type":"education","lineage":["https://openalex.org/I95023434"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Jaclyn K. Mann","raw_affiliation_strings":["HIV Pathogenesis Programme, Doris Duke Medical Research Institute, KwaZulu-Natal Research Institute for Tuberculosis and HIV, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HIV Pathogenesis Programme, Doris Duke Medical Research Institute, KwaZulu-Natal Research Institute for Tuberculosis and HIV, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa","institution_ids":["https://openalex.org/I95023434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010085708","display_name":"Manjeetha Jaggernath","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95023434","display_name":"University of KwaZulu-Natal","ror":"https://ror.org/04qzfn040","country_code":"ZA","type":"education","lineage":["https://openalex.org/I95023434"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Manjeetha Jaggernath","raw_affiliation_strings":["HIV Pathogenesis Programme, Doris Duke Medical Research Institute, KwaZulu-Natal Research Institute for Tuberculosis and HIV, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HIV Pathogenesis Programme, Doris Duke Medical Research Institute, KwaZulu-Natal Research Institute for Tuberculosis and HIV, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa","institution_ids":["https://openalex.org/I95023434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084603123","display_name":"Seung-Gu Kang","orcid":"https://orcid.org/0000-0002-4010-0829","observed_orcids":["https://orcid.org/0000-0002-4010-0829"]},"institutions":[{"id":"https://openalex.org/I4210114115","display_name":"IBM Research - Thomas J. Watson Research Center","ror":"https://ror.org/0265w5591","country_code":"US","type":"facility","lineage":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Seung-gu Kang","raw_affiliation_strings":["Computational Biology Center, IBM Thomas J. Watson Research Center, Yorktown Heights, New York, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Biology Center, IBM Thomas J. Watson Research Center, Yorktown Heights, New York, United States of America","institution_ids":["https://openalex.org/I4210114115"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Christian K\u00f6rner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137251492","display_name":"Leibniz Institute of Virology (LIV)","ror":"https://ror.org/02r2q1d96","country_code":"DE","type":"facility","lineage":["https://openalex.org/I137251492","https://openalex.org/I315704651"]},{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Christian K\u00f6rner","raw_affiliation_strings":["Heinrich-Pette-Institut, Leibniz Institute for Experimental Virology, Hamburg, Germany","Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Heinrich-Pette-Institut, Leibniz Institute for Experimental Virology, Hamburg, Germany","institution_ids":["https://openalex.org/I137251492"]},{"raw_affiliation_string":"Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America","institution_ids":["https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076840670","display_name":"Amy W. Chung","orcid":"https://orcid.org/0000-0003-0020-9704","observed_orcids":["https://orcid.org/0000-0003-0020-9704"]},"institutions":[{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy W. Chung","raw_affiliation_strings":["Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America","institution_ids":["https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067172317","display_name":"Jamie L. Schafer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jamie L. Schafer","raw_affiliation_strings":["Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America","Division of Microbiology, New England Primate Research Center, Southborough, Massachusetts, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Microbiology, New England Primate Research Center, Southborough, Massachusetts, United States of America","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002318123","display_name":"David T. Evans","orcid":"https://orcid.org/0000-0003-2498-6292","observed_orcids":["https://orcid.org/0000-0003-2498-6292"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David T. Evans","raw_affiliation_strings":["Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America","Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, Madison, Wisconsin, United States of America","Division of Microbiology, New England Primate Research Center, Southborough, Massachusetts, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, Madison, Wisconsin, United States of America","institution_ids":["https://openalex.org/I135310074"]},{"raw_affiliation_string":"Division of Microbiology, New England Primate Research Center, Southborough, Massachusetts, United States of America","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059371880","display_name":"Galit Alter","orcid":"https://orcid.org/0000-0002-7680-9215","observed_orcids":["https://orcid.org/0000-0002-7680-9215","https://orcid.org/0000-0002-9221-6735","https://orcid.org/0000-0003-1570-9445"]},"institutions":[{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Galit Alter","raw_affiliation_strings":["Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America","institution_ids":["https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016518899","display_name":"Bruce D. Walker","orcid":"https://orcid.org/0000-0001-6122-9245","observed_orcids":["https://orcid.org/0000-0001-6122-9245","https://orcid.org/0000-0002-8506-6740"]},"institutions":[{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bruce D. Walker","raw_affiliation_strings":["Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America","institution_ids":["https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043346206","display_name":"Philip Goulder","orcid":"https://orcid.org/0000-0002-9842-4674","observed_orcids":["https://orcid.org/0000-0002-9842-4674"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I95023434","display_name":"University of KwaZulu-Natal","ror":"https://ror.org/04qzfn040","country_code":"ZA","type":"education","lineage":["https://openalex.org/I95023434"]}],"countries":["GB","ZA"],"is_corresponding":false,"raw_author_name":"Philip J. Goulder","raw_affiliation_strings":["Department of Paediatrics, University of Oxford, Oxford, United Kingdom","HIV Pathogenesis Programme, Doris Duke Medical Research Institute, KwaZulu-Natal Research Institute for Tuberculosis and HIV, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics, University of Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I40120149"]},{"raw_affiliation_string":"HIV Pathogenesis Programme, Doris Duke Medical Research Institute, KwaZulu-Natal Research Institute for Tuberculosis and HIV, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa","institution_ids":["https://openalex.org/I95023434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015541994","display_name":"Mary N Carrington","orcid":"https://orcid.org/0000-0002-2692-2180","observed_orcids":["https://orcid.org/0000-0002-2692-2180"]},"institutions":[{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4396570585","display_name":"Leidos Biomedical Research Inc. (United States)","ror":"https://ror.org/00bardy64","country_code":"US","type":"company","lineage":["https://openalex.org/I114662689","https://openalex.org/I4396570585"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary Carrington","raw_affiliation_strings":["Cancer and Inflammation Program, Laboratory of Experimental Immunology, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America","Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer and Inflammation Program, Laboratory of Experimental Immunology, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4396570585"]},{"raw_affiliation_string":"Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America","institution_ids":["https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020960834","display_name":"Pia Hartmann","orcid":"https://orcid.org/0000-0003-4174-3268","observed_orcids":["https://orcid.org/0000-0003-4174-3268"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Pia Hartmann","raw_affiliation_strings":["First Department of Internal Medicine, Division of Infectious Diseases, University of Cologne, Cologne, Germany","Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Internal Medicine, Division of Infectious Diseases, University of Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762"]},{"raw_affiliation_string":"Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007161976","display_name":"Thomas Pertel","orcid":"https://orcid.org/0000-0002-2286-6011","observed_orcids":["https://orcid.org/0000-0002-2286-6011"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas Pertel","raw_affiliation_strings":["Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078014032","display_name":"Ruhong Zhou","orcid":"https://orcid.org/0000-0001-8624-5591","observed_orcids":["https://orcid.org/0000-0001-8624-5591"]},"institutions":[{"id":"https://openalex.org/I4210114115","display_name":"IBM Research - Thomas J. Watson Research Center","ror":"https://ror.org/0265w5591","country_code":"US","type":"facility","lineage":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ruhong Zhou","raw_affiliation_strings":["Computational Biology Center, IBM Thomas J. Watson Research Center, Yorktown Heights, New York, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Biology Center, IBM Thomas J. Watson Research Center, Yorktown Heights, New York, United States of America","institution_ids":["https://openalex.org/I4210114115"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040954811","display_name":"Thumbi Ndung\u2019u","orcid":"https://orcid.org/0000-0003-2962-3992","observed_orcids":["https://orcid.org/0000-0003-2962-3992"]},"institutions":[{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I4210087223","display_name":"Max Planck Institute for Infection Biology","ror":"https://ror.org/0046gcs23","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210087223"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]},{"id":"https://openalex.org/I95023434","display_name":"University of KwaZulu-Natal","ror":"https://ror.org/04qzfn040","country_code":"ZA","type":"education","lineage":["https://openalex.org/I95023434"]}],"countries":["DE","US","ZA"],"is_corresponding":false,"raw_author_name":"Thumbi Ndung\u2019u","raw_affiliation_strings":["HIV Pathogenesis Programme, Doris Duke Medical Research Institute, KwaZulu-Natal Research Institute for Tuberculosis and HIV, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa","KwaZulu-Natal Research Institute for Tuberculosis and HIV, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa","Max Planck Institute for Infection Biology, Berlin, Germany","Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HIV Pathogenesis Programme, Doris Duke Medical Research Institute, KwaZulu-Natal Research Institute for Tuberculosis and HIV, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa","institution_ids":["https://openalex.org/I95023434"]},{"raw_affiliation_string":"KwaZulu-Natal Research Institute for Tuberculosis and HIV, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa","institution_ids":["https://openalex.org/I95023434"]},{"raw_affiliation_string":"Max Planck Institute for Infection Biology, Berlin, Germany","institution_ids":["https://openalex.org/I4210087223"]},{"raw_affiliation_string":"Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America","institution_ids":["https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042817775","display_name":"Marcus A. Altfeld","orcid":"https://orcid.org/0000-0001-5972-2997","observed_orcids":["https://orcid.org/0000-0001-5972-2997"]},"institutions":[{"id":"https://openalex.org/I137251492","display_name":"Leibniz Institute of Virology (LIV)","ror":"https://ror.org/02r2q1d96","country_code":"DE","type":"facility","lineage":["https://openalex.org/I137251492","https://openalex.org/I315704651"]},{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["DE","US"],"is_corresponding":true,"raw_author_name":"Marcus Altfeld","raw_affiliation_strings":["Heinrich-Pette-Institut, Leibniz Institute for Experimental Virology, Hamburg, Germany","Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Heinrich-Pette-Institut, Leibniz Institute for Experimental Virology, Hamburg, Germany","institution_ids":["https://openalex.org/I137251492"]},{"raw_affiliation_string":"Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America","institution_ids":["https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":16,"corresponding_author_ids":["https://openalex.org/A5042817775"],"corresponding_institution_ids":["https://openalex.org/I137251492","https://openalex.org/I2802422659","https://openalex.org/I63966007"],"apc_list":{"value":6460,"currency":"USD","value_usd":6460},"apc_paid":{"value":6460,"currency":"USD","value_usd":6460},"fwci":5.0515,"has_fulltext":true,"cited_by_count":80,"citation_normalized_percentile":{"value":0.96224894,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"12","issue":"11","first_page":"e1001900","last_page":"e1001900"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.6449999809265137,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.6449999809265137,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.35109999775886536,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-1","display_name":"HIV-1","score":0.8769999742507935},{"id":"https://openalex.org/keywords/kir2dl3","display_name":"KIR2DL3","score":0.9980000257492065},{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.9229999780654907},{"id":"https://openalex.org/keywords/viral-immune-evasion","display_name":"viral immune evasion","score":0.6480000019073486},{"id":"https://openalex.org/keywords/hiv-1-subtype-c","display_name":"HIV-1 subtype C","score":0.7559999823570251},{"id":"https://openalex.org/keywords/inhibitory-receptors","display_name":"inhibitory receptors","score":0.4569999873638153}],"concepts":[{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.7498650550842285},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6173213720321655},{"id":"https://openalex.org/C188280979","wikidata":"https://www.wikidata.org/wiki/Q911125","display_name":"Human leukocyte antigen","level":3,"score":0.6082543730735779},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6032639145851135},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5731346011161804},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5196365118026733},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.5081503391265869},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4481948912143707},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.3262668251991272},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.29621151089668274},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012367","descriptor_name":"RNA, Viral","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013019","descriptor_name":"South Africa","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015236","descriptor_name":"HLA-C Antigens","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015236","descriptor_name":"HLA-C Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016655","descriptor_name":"HIV Core Protein p24","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054301","descriptor_name":"gag Gene Products, Human Immunodeficiency Virus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D054344","descriptor_name":"Receptors, KIR2DL3","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D057131","descriptor_name":"Immune Evasion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":14,"locations":[{"id":"doi:10.1371/journal.pmed.1001900","doi":"https://doi.org/10.1371/journal.pmed.1001900","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pmed.1001900","pdf_url":"https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1001900&type=printable","source":{"id":"https://openalex.org/S197939330","display_name":"PLoS Medicine","issn_l":"1549-1277","issn":["1549-1277","1549-1676"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Medicine","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3627851","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4648589","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4648589","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4648589","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Med","raw_type":"Text"},{"id":"pmid:26575988","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26575988","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS medicine","raw_type":"Journal Article"},{"id":"pmh:oai:USBKOELN.ub.uni-koeln.de:38783","doi":null,"is_oa":false,"landing_page_url":"https://kups.ub.uni-koeln.de/38783/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400371","display_name":"K\u00f6lner Universit\u00e4ts PublikationsServer (Universit\u00e4t zu K\u00f6ln)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210115942","host_organization_name":"Rhenish Institute for Environmental Research","host_organization_lineage":["https://openalex.org/I4210115942"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"doc-type:article"},{"id":"pmh:oai:pure.amsterdamumc.nl:openaire/52d23d96-f661-44ce-8eca-2f12793e75be","doi":null,"is_oa":true,"landing_page_url":"https://pure.amsterdamumc.nl/en/publications/52d23d96-f661-44ce-8eca-2f12793e75be","pdf_url":null,"source":{"id":"https://openalex.org/S7407055222","display_name":"Pure Amsterdam UMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:dspace.mit.edu:1721.1/100696","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1721.1/100696","pdf_url":"https://dspace.mit.edu/bitstreams/c9018165-0f8d-4db6-920d-22592c1653d1/download","source":{"id":"https://openalex.org/S4306400425","display_name":"DSpace@MIT (Massachusetts Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I63966007","host_organization_name":"Massachusetts Institute of Technology","host_organization_lineage":["https://openalex.org/I63966007"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Public Library of Science","raw_type":"Article"},{"id":"pmh:oai:dash.harvard.edu:1/23845378","doi":null,"is_oa":true,"landing_page_url":"http://nrs.harvard.edu/urn-3:HUL.InstRepos:23845378","pdf_url":null,"source":{"id":"https://openalex.org/S4306401540","display_name":"Digital Access to Scholarship at Harvard (DASH) (Harvard University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I136199984","host_organization_name":"Harvard University","host_organization_lineage":["https://openalex.org/I136199984"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},{"id":"pmh:amcpub:oai:pure.amc.nl:publications/085db958-9b05-484f-b06f-f9d42ca6bf2a","doi":null,"is_oa":false,"landing_page_url":"https://pure.amc.nl/en/publications/selection-of-an-hlac0304restricted-hiv1-p24-gag-sequence-variant-is-associated-with-viral-escape-from-kir2dl3-natural-killer-cells-data-from-an-observational-cohort-in-south-africa(085db958-9b05-484f-b06f-f9d42ca6bf2a).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS medicine, 12(11). Public Library of Science","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:fa6dc56a9531426d9574a273ad87bc21","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/fa6dc56a9531426d9574a273ad87bc21","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Medicine, Vol 12, Iss 11, p e1001900; discussion e1001900 (2015)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/1608555","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/_Selection_of_an_HLA_C_03_04_Restricted_HIV_1_p24_Gag_Sequence_Variant_Is_Associated_with_Viral_Escape_from_KIR2DL3_Natural_Killer_Cells_Data_from_an_Observational_Cohort_in_South_Africa_/1608555","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:jupiter.its.unimelb.edu.au:11343/269181","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/11343/269181","pdf_url":null,"source":{"id":"https://openalex.org/S4377196259","display_name":"Minerva Access (University of Melbourne)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I165779595","host_organization_name":"The University of Melbourne","host_organization_lineage":["https://openalex.org/I165779595"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"},{"id":"pmh:oai:pure.mpg.de:item_2247204","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/11858/00-001M-0000-0029-7974-C","pdf_url":null,"source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Medicine","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2234164285","doi":null,"is_oa":false,"landing_page_url":"https://dspace.mit.edu/handle/1721.1/100696","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1371/journal.pmed.1001900","doi":"https://doi.org/10.1371/journal.pmed.1001900","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pmed.1001900","pdf_url":"https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1001900&type=printable","source":{"id":"https://openalex.org/S197939330","display_name":"PLoS Medicine","issn_l":"1549-1277","issn":["1549-1277","1549-1676"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1203476693","display_name":null,"funder_award_id":"AI060354","funder_id":"https://openalex.org/F4320332582","funder_display_name":"Center for AIDS Research, University of Washington"},{"id":"https://openalex.org/G1521411027","display_name":null,"funder_award_id":"No. HHSN261200800001E","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G1575283533","display_name":null,"funder_award_id":"P30 AI060354","funder_id":"https://openalex.org/F4320309654","funder_display_name":"Harvard University Center for AIDS Research"},{"id":"https://openalex.org/G1722716446","display_name":null,"funder_award_id":"P30 AI060354","funder_id":"https://openalex.org/F4320332582","funder_display_name":"Center for AIDS Research, University of Washington"},{"id":"https://openalex.org/G2225693873","display_name":null,"funder_award_id":"N0I-AI-15422","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G2805213485","display_name":"Fcgamma receptor-mediated suppression of immunodeficiency virus replication","funder_award_id":"R01AI121135","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G2833052009","display_name":"Klinische Forschergruppe in der klinischen Infektiologie: HIV-Infektion und Infektionen bei Immunsuppression","funder_award_id":"01KI1017","funder_id":"https://openalex.org/F4320321114","funder_display_name":"Bundesministerium f\u00fcr Bildung und Forschung"},{"id":"https://openalex.org/G3125303757","display_name":null,"funder_award_id":"102468","funder_id":"https://openalex.org/F4320320671","funder_display_name":"National Research Foundation"},{"id":"https://openalex.org/G3390473937","display_name":"Lentiviral Resistance to Tetherin","funder_award_id":"R01AI098485","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G345173699","display_name":null,"funder_award_id":"P30AI060354","funder_id":"https://openalex.org/F4320309622","funder_display_name":"Harvard University"},{"id":"https://openalex.org/G3503792436","display_name":null,"funder_award_id":"#HHSN261200800001E","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3522989319","display_name":"Medical Scientist Training Program","funder_award_id":"T32GM007753","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G3544613207","display_name":null,"funder_award_id":"AI060354","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G3547560438","display_name":null,"funder_award_id":"HHSN261200800001E","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G379698727","display_name":null,"funder_award_id":"R01AI066031","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G386607036","display_name":null,"funder_award_id":"HHSN261200800001E)","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4585269469","display_name":null,"funder_award_id":"HHSN261200800001E","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G468792422","display_name":null,"funder_award_id":"P30-AI060354","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G4756138391","display_name":null,"funder_award_id":"HHSN261200800001E","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G4825398269","display_name":"Pathogenesis of Clade C HIV Infection","funder_award_id":"R01AI067073","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G4988656331","display_name":null,"funder_award_id":"HHSN261200800001E.","funder_id":"https://openalex.org/F4320313762","funder_display_name":"Frederick National Laboratory for Cancer Research"},{"id":"https://openalex.org/G5366891077","display_name":null,"funder_award_id":"HHSN261200800001E","funder_id":"https://openalex.org/F4320313818","funder_display_name":"Ragon Institute of MGH, MIT and Harvard"},{"id":"https://openalex.org/G5520316217","display_name":null,"funder_award_id":"NIH-R01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5632802793","display_name":"Natural Killer Cell Mediated Recognition of HIV-1 and Adaption to KIR and HLA.","funder_award_id":"102468","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G5737582129","display_name":null,"funder_award_id":"HHSN261200800001E","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5767575880","display_name":null,"funder_award_id":"R0I AI 067073","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5803924101","display_name":null,"funder_award_id":"AI095098","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5867949827","display_name":null,"funder_award_id":"HHSN261200800001E","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5888954722","display_name":null,"funder_award_id":"HHSN261200800001C","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6132644515","display_name":"Identifying the ligand for the activating NK cell receptor KIR3DS1 and its protective role in HIV-1 disease progression","funder_award_id":"F31AI116366","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G6741032483","display_name":"Natural Killer Cell Mediated Recognition of HIV-1 and Adaption to KIR and HLA.","funder_award_id":"102468/Z/13/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G7111603537","display_name":"KIR and MHC Class I Immunogenetics in SIV Infection","funder_award_id":"R01AI095098","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G7300258001","display_name":null,"funder_award_id":"15422","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G7785852513","display_name":null,"funder_award_id":"AI060354","funder_id":"https://openalex.org/F4320309654","funder_display_name":"Harvard University Center for AIDS Research"},{"id":"https://openalex.org/G7990289701","display_name":"Optimizing CD8+ T-cell responses against C clade HIV infection in subSaharan Afri","funder_award_id":"R01AI046995","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G8129502736","display_name":"Mechanisms of HIV disease limitation and cure revealed in paediatric infection .","funder_award_id":"104748","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G8245670873","display_name":null,"funder_award_id":"NIH R01","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8447644256","display_name":null,"funder_award_id":"HHSN261200800001E","funder_id":"https://openalex.org/F4320306082","funder_display_name":"Howard Hughes Medical Institute"},{"id":"https://openalex.org/G9000108697","display_name":null,"funder_award_id":"AI067073","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000180070","display_name":null,"funder_award_id":"AI095098","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000904381","display_name":"Harvard University Center for AIDS Research","funder_award_id":"P30AI060354","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320306082","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90"},{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320309622","display_name":"Harvard University","ror":"https://ror.org/03vek6s52"},{"id":"https://openalex.org/F4320309654","display_name":"Harvard University Center for AIDS Research","ror":null},{"id":"https://openalex.org/F4320311052","display_name":"Deutsches Zentrum f\u00fcr Infektionsforschung","ror":"https://ror.org/028s4q594"},{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320313762","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209"},{"id":"https://openalex.org/F4320313818","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13"},{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"},{"id":"https://openalex.org/F4320320875","display_name":"Deutscher Akademischer Austauschdienst","ror":"https://ror.org/039djdh30"},{"id":"https://openalex.org/F4320321114","display_name":"Bundesministerium f\u00fcr Bildung und Forschung","ror":"https://ror.org/04pz7b180"},{"id":"https://openalex.org/F4320331776","display_name":"Victor Daitz Foundation","ror":"https://ror.org/02g0cdm62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332582","display_name":"Center for AIDS Research, University of Washington","ror":"https://ror.org/00cvxb145"},{"id":"https://openalex.org/F4320334763","display_name":"Leibniz-Gemeinschaft","ror":"https://ror.org/01n6r0e97"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337358","display_name":"National Center for Complementary and Alternative Medicine","ror":"https://ror.org/00190t495"},{"id":"https://openalex.org/F4320338413","display_name":"Cilag","ror":"https://ror.org/02fe4h741"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2175125998.pdf","grobid_xml":"https://content.openalex.org/works/W2175125998.grobid-xml"},"referenced_works_count":68,"referenced_works":["https://openalex.org/W1577109789","https://openalex.org/W1606271020","https://openalex.org/W1963603829","https://openalex.org/W1964895626","https://openalex.org/W1965696330","https://openalex.org/W1966388845","https://openalex.org/W1969814796","https://openalex.org/W1975440573","https://openalex.org/W1980674913","https://openalex.org/W1985322758","https://openalex.org/W1986152436","https://openalex.org/W1987999246","https://openalex.org/W1990123254","https://openalex.org/W1993071851","https://openalex.org/W1995119371","https://openalex.org/W1995224930","https://openalex.org/W1997714286","https://openalex.org/W1998380792","https://openalex.org/W2001372707","https://openalex.org/W2003515818","https://openalex.org/W2004822121","https://openalex.org/W2009082439","https://openalex.org/W2009328680","https://openalex.org/W2009418845","https://openalex.org/W2022069273","https://openalex.org/W2034207391","https://openalex.org/W2037154691","https://openalex.org/W2040133121","https://openalex.org/W2045062204","https://openalex.org/W2045551237","https://openalex.org/W2047353087","https://openalex.org/W2058321555","https://openalex.org/W2070712449","https://openalex.org/W2071960463","https://openalex.org/W2076225720","https://openalex.org/W2095464003","https://openalex.org/W2095603321","https://openalex.org/W2097126893","https://openalex.org/W2099272076","https://openalex.org/W2100199918","https://openalex.org/W2105090013","https://openalex.org/W2112110584","https://openalex.org/W2114201919","https://openalex.org/W2114641463","https://openalex.org/W2115730533","https://openalex.org/W2118619556","https://openalex.org/W2121158936","https://openalex.org/W2121546980","https://openalex.org/W2122132317","https://openalex.org/W2125377484","https://openalex.org/W2127707746","https://openalex.org/W2128306333","https://openalex.org/W2131184245","https://openalex.org/W2136542540","https://openalex.org/W2137675187","https://openalex.org/W2142489038","https://openalex.org/W2146273335","https://openalex.org/W2147134928","https://openalex.org/W2149805171","https://openalex.org/W2150120088","https://openalex.org/W2155721915","https://openalex.org/W2158357183","https://openalex.org/W2158972490","https://openalex.org/W2159013694","https://openalex.org/W2164213171","https://openalex.org/W2168688111","https://openalex.org/W2169847792","https://openalex.org/W2170019076"],"related_works":["https://openalex.org/W2040133121","https://openalex.org/W3009137713","https://openalex.org/W7066340086","https://openalex.org/W3092574047","https://openalex.org/W1977258691","https://openalex.org/W2163802631","https://openalex.org/W2079099089","https://openalex.org/W2143808879","https://openalex.org/W1963603829","https://openalex.org/W2339522572"],"abstract_inverted_index":{"BACKGROUND:":[0],"Viruses":[1],"can":[2,33,259],"evade":[3,34,260],"immune":[4,36,290,308],"surveillance,":[5],"but":[6],"the":[7,18,49,117,130,168,179,190,213,216,237,245,265,283,293,303,312],"underlying":[8],"mechanisms":[9,19,284],"are":[10],"insufficiently":[11],"understood.":[12],"Here,":[13],"we":[14],"sought":[15],"to":[16,121,129,163,176,230,275,310],"understand":[17],"by":[20,285],"which":[21,286],"natural":[22,242],"killer":[23],"(NK)":[24],"cells":[25,28,83,123,157,166,177],"recognize":[26],"HIV-1-infected":[27],"and":[29,110,141,193,205,233,244,292],"how":[30,257],"this":[31,125],"virus":[32],"NK-cell-mediated":[35,289],"pressure.":[37],"METHODS":[38],"AND":[39],"FINDINGS:":[40],"Two":[41],"sequence":[42,85,93,181,219],"mutations":[43,268],"in":[44,58,71,104,161,174,212,241,269],"p24":[45,99],"Gag":[46,100],"associated":[47],"with":[48,107],"presence":[50],"of":[51,67,98,116,153,189,209,215,236,267,282,296,305,315],"specific":[52],"KIR/HLA":[53],"combined":[54],"genotypes":[55],"were":[56],"identified":[57],"HIV-1":[59,239,287],"clade":[60],"C":[61],"viruses":[62,258],"from":[63,80,158],"a":[64,297],"large":[65],"cohort":[66],"infected,":[68],"untreated":[69],"individuals":[70,106],"South":[72],"Africa":[73],"(n":[74],"=":[75,149,201],"392),":[76],"suggesting":[77],"viral":[78,218,248],"escape":[79],"KIR+":[81],"NK":[82,156,261,277,316],"through":[84,264],"variations":[86],"within":[87],"HLA":[88],"class":[89],"I-presented":[90],"epitopes.":[91],"One":[92],"polymorphism":[94],"at":[95],"position":[96],"303":[97],"(TGag303V),":[101],"selected":[102],"for":[103,247],"infected":[105],"both":[108],"KIR2DL3":[109,119],"HLA-C*03:04,":[111],"enabled":[112],"significantly":[113,172],"better":[114],"binding":[115,274],"inhibitory":[118,276],"receptor":[120],"HLA-C*03:04-expressing":[122],"presenting":[124,167,178],"variant":[126,142,169,194],"epitope":[127,132,170,240],"compared":[128],"wild-type":[131,180],"(wild-type":[133,182],"mean":[134,143,183,191,195],"18.01":[135],"\u00b1":[136,145,185,197],"10.45":[137],"standard":[138,187],"deviation":[139],"[SD]":[140],"44.67":[144],"14.42":[146],"SD,":[147],"p":[148,200],"0.002).":[150],"Furthermore,":[151],"activation":[152],"primary":[154],"KIR2DL3+":[155],"healthy":[159],"donors":[160],"response":[162],"HLA-C*03:04+":[164],"target":[165],"was":[171],"reduced":[173],"comparison":[175],"0.78":[184],"0.07":[186,198],"error":[188],"[SEM]":[192],"0.63":[196],"SEM,":[199],"0.012).":[202],"Structural":[203],"modeling":[204,299],"surface":[206],"plasmon":[207],"resonance":[208],"KIR/peptide/HLA":[210],"interactions":[211],"context":[214],"different":[217],"variants":[220],"studied":[221],"supported":[222],"these":[223],"results.":[224],"Future":[225],"studies":[226],"will":[227,301],"be":[228],"needed":[229],"assess":[231],"processing":[232],"antigen":[234],"presentation":[235],"investigated":[238],"infection,":[243],"consequences":[246],"control.":[249],"CONCLUSIONS:":[250],"These":[251],"data":[252],"provide":[253],"novel":[254,306],"insights":[255],"into":[256],"cell":[262,278],"immunity":[263],"selection":[266],"HLA-presented":[270],"epitopes":[271],"that":[272],"enhance":[273],"receptors.":[279],"Better":[280],"understanding":[281],"evades":[288],"pressure":[291],"functional":[294],"validation":[295],"structural":[298],"approach":[300],"facilitate":[302],"development":[304],"targeted":[307],"interventions":[309],"harness":[311],"antiviral":[313],"activities":[314],"cells.":[317]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":15},{"year":2016,"cited_by_count":12}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}