{"id":"https://openalex.org/W21751063","doi":"https://doi.org/10.33588/rn.5511.2012398","title":"Levodopa en el tratamiento de la enfermedad de Parkinson: mitos y realidades","display_name":"Levodopa en el tratamiento de la enfermedad de Parkinson: mitos y realidades","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W21751063","doi":"https://doi.org/10.33588/rn.5511.2012398","mag":"21751063","pmid":"https://pubmed.ncbi.nlm.nih.gov/23172094"},"language":"es","primary_location":{"id":"doi:10.33588/rn.5511.2012398","doi":"https://doi.org/10.33588/rn.5511.2012398","is_oa":false,"landing_page_url":"https://doi.org/10.33588/rn.5511.2012398","pdf_url":null,"source":{"id":"https://openalex.org/S184263677","display_name":"Revista de Neurolog\u00eda","issn_l":"0210-0010","issn":["0210-0010","1576-6578"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4322632785","host_organization_name":"Viguera Publishers","host_organization_lineage":["https://openalex.org/P4322632785"],"host_organization_lineage_names":["Viguera Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista de Neurolog\u00eda","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10651/23884","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047004228","display_name":"M. R. Luqu\u00edn","orcid":"https://orcid.org/0000-0002-5594-1794","observed_orcids":["https://orcid.org/0000-0002-5594-1794"]},"institutions":[{"id":"https://openalex.org/I4210135003","display_name":"Clinica Universidad de Navarra","ror":"https://ror.org/03phm3r45","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210135003"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"M\u00aa Rosario Luquin Piudo","raw_affiliation_strings":["Servicios de Neurolog\u00eda, Cl\u00ednica Universidad de Navarra, Pamplona, Navarra, Espa\u00f1a. rluquin@unav.es"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicios de Neurolog\u00eda, Cl\u00ednica Universidad de Navarra, Pamplona, Navarra, Espa\u00f1a. rluquin@unav.es","institution_ids":["https://openalex.org/I4210135003"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086397597","display_name":"Pedro Ruiz","orcid":"https://orcid.org/0000-0001-6194-672X","observed_orcids":["https://orcid.org/0000-0001-6194-672X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pedro Jos\u00e9 Garc\u00eda Ruiz-Espiga","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061421108","display_name":"Mar\u00eda Jos\u00e9 Mart\u00ed","orcid":"https://orcid.org/0000-0002-3874-967X","observed_orcids":["https://orcid.org/0000-0002-3874-967X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maria Jose Mart\u00ed","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Ana Rojo Sebasti\u00e1n","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ana Rojo Sebasti\u00e1n","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059104369","display_name":"Lydia Vela","orcid":"https://orcid.org/0000-0001-6663-395X","observed_orcids":["https://orcid.org/0000-0001-6663-395X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lydia Vela Desojo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110665582","display_name":"Francisco Grandas","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Francisco Javier Grandas P\u00e9rez","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064413008","display_name":"Mariano Bravo-Utrera","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mariano Bravo Utrera","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081010425","display_name":"Juan Andr\u00e9s Burguera","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Juan Andr\u00e9s Burguera Hern\u00e1ndez","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103348651","display_name":"Jos\u00e9 Chac\u00f3n","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Rafael Chac\u00f3n Pe\u00f1a","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003048892","display_name":"V\u00edctor M. Campos Arillo","orcid":"https://orcid.org/0000-0003-3621-0782","observed_orcids":["https://orcid.org/0000-0003-3621-0782"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V\u00edctor M. Campos Arillo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032253499","display_name":"Carmen Dur\u00e1n-Herrera","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carmen Dur\u00e1n Herrera","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Jos\u00e9 Manuel Fern\u00e1ndez Garc\u00eda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Manuel Fern\u00e1ndez Garc\u00eda","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078734806","display_name":"R. Garc\u00eda-Ramos","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Roc\u00edo Garc\u00eda-Ramos Garc\u00eda","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072960017","display_name":"Juan Carlos G\u00f3mez\u2010Esteban","orcid":"https://orcid.org/0000-0002-4697-3890","observed_orcids":["https://orcid.org/0000-0002-4697-3890"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Juan Carlos G\u00f3mez Esteban","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017629107","display_name":"Javier Gutierrez","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Javier Guti\u00e9rrez","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Juan Juni Sanahuja","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Juan Juni Sanahuja","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Marina Mata \u00c1lvarez-Santullano","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marina Mata \u00c1lvarez-Santullano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101863828","display_name":"Juan Carlos Mart\u00ednez\u2010Castrillo","orcid":"https://orcid.org/0000-0001-7744-6850","observed_orcids":["https://orcid.org/0000-0001-7744-6850"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Juan Carlos Mart\u00ednez Castrillo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Jes\u00fas Olivares Romero","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jes\u00fas Olivares Romero","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109118548","display_name":"R. Ribacoba-Montero","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ren\u00e9e Ribacoba Montero","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007138149","display_name":"Diego Santos\u2010Garc\u00eda","orcid":"https://orcid.org/0000-0002-3126-5111","observed_orcids":["https://orcid.org/0000-0002-3126-5111"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Diego Santos Garc\u00eda","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111062834","display_name":"Mar\u00eda Sierra","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mar\u00eda Sierra","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5039691676","display_name":"Caridad Valero Merino","orcid":"https://orcid.org/0000-0003-4027-0999","observed_orcids":["https://orcid.org/0000-0003-4027-0999"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Caridad Valero Merino","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9969,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.73869884,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"55","issue":"11","first_page":"669","last_page":"669"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10919","display_name":"Deep Brain Stimulation and Movement Disorders","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13991","display_name":"Nuclear Receptors and Signaling","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/levodopa","display_name":"levodopa","score":0.9860000014305115},{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.996999979019165},{"id":"https://openalex.org/keywords/dopamine-agonists","display_name":"dopamine agonists","score":0.9990000128746033},{"id":"https://openalex.org/keywords/dyskinesia","display_name":"dyskinesia","score":0.9129999876022339},{"id":"https://openalex.org/keywords/motor-fluctuations","display_name":"motor fluctuations","score":0.9929999709129333},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.9190000295639038},{"id":"https://openalex.org/keywords/levodopa-side-effects","display_name":"levodopa side effects","score":0.7360000014305115},{"id":"https://openalex.org/keywords/treatment-selection","display_name":"treatment selection","score":0.38999998569488525}],"concepts":[{"id":"https://openalex.org/C2780304432","wikidata":"https://www.wikidata.org/wiki/Q300989","display_name":"Levodopa","level":4,"score":0.9392238855361938},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.5896141529083252},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.5692751407623291},{"id":"https://openalex.org/C2780405171","wikidata":"https://www.wikidata.org/wiki/Q629444","display_name":"Dyskinesia","level":4,"score":0.5605199933052063},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.49903035163879395},{"id":"https://openalex.org/C16568411","wikidata":"https://www.wikidata.org/wiki/Q83042","display_name":"Neurology","level":2,"score":0.47793060541152954},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4451253116130829},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.44289863109588623},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.410372257232666},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.31428253650665283},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.20457738637924194},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.16656336188316345}],"mesh":[{"descriptor_ui":"D000978","descriptor_name":"Antiparkinson Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000978","descriptor_name":"Antiparkinson Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001523","descriptor_name":"Mental Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007980","descriptor_name":"Levodopa","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007980","descriptor_name":"Levodopa","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012893","descriptor_name":"Sleep Wake Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.33588/rn.5511.2012398","doi":"https://doi.org/10.33588/rn.5511.2012398","is_oa":false,"landing_page_url":"https://doi.org/10.33588/rn.5511.2012398","pdf_url":null,"source":{"id":"https://openalex.org/S184263677","display_name":"Revista de Neurolog\u00eda","issn_l":"0210-0010","issn":["0210-0010","1576-6578"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4322632785","host_organization_name":"Viguera Publishers","host_organization_lineage":["https://openalex.org/P4322632785"],"host_organization_lineage_names":["Viguera Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista de Neurolog\u00eda","raw_type":"journal-article"},{"id":"pmid:23172094","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23172094","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista de neurologia","raw_type":"English Abstract"},{"id":"pmh:oai:digibuo.uniovi.es:10651/23884","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10651/23884","pdf_url":null,"source":{"id":"https://openalex.org/S4306402334","display_name":"Consultation of the Doctoral Thesis Database (TESEO) (Ministerio de Educaci\u00f3n, Cultura y Deporte)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801976130","host_organization_name":"Ministerio de Educaci\u00f3n Cultura y Deporte","host_organization_lineage":["https://openalex.org/I2801976130"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scopus","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:digibuo.uniovi.es:10651/23884","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10651/23884","pdf_url":null,"source":{"id":"https://openalex.org/S4306402334","display_name":"Consultation of the Doctoral Thesis Database (TESEO) (Ministerio de Educaci\u00f3n, Cultura y Deporte)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801976130","host_organization_name":"Ministerio de Educaci\u00f3n Cultura y Deporte","host_organization_lineage":["https://openalex.org/I2801976130"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scopus","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":129,"referenced_works":["https://openalex.org/W62865870","https://openalex.org/W95961711","https://openalex.org/W170256281","https://openalex.org/W176318346","https://openalex.org/W1489370470","https://openalex.org/W1509320943","https://openalex.org/W1517507381","https://openalex.org/W1533056363","https://openalex.org/W1539830142","https://openalex.org/W1649311764","https://openalex.org/W1897702216","https://openalex.org/W1966831812","https://openalex.org/W1968545875","https://openalex.org/W1969522203","https://openalex.org/W1969889432","https://openalex.org/W1971654722","https://openalex.org/W1972684129","https://openalex.org/W1973001146","https://openalex.org/W1973450653","https://openalex.org/W1973698406","https://openalex.org/W1975059589","https://openalex.org/W1977198160","https://openalex.org/W1978396720","https://openalex.org/W1978983890","https://openalex.org/W1979036437","https://openalex.org/W1981613318","https://openalex.org/W1982523487","https://openalex.org/W1982535961","https://openalex.org/W1985814672","https://openalex.org/W1989159103","https://openalex.org/W1992465464","https://openalex.org/W1992486358","https://openalex.org/W1994886820","https://openalex.org/W1997185618","https://openalex.org/W1997887984","https://openalex.org/W1998750126","https://openalex.org/W1998810777","https://openalex.org/W1999018495","https://openalex.org/W2001437598","https://openalex.org/W2002469891","https://openalex.org/W2002751958","https://openalex.org/W2003326996","https://openalex.org/W2005242511","https://openalex.org/W2006300801","https://openalex.org/W2006764831","https://openalex.org/W2007028483","https://openalex.org/W2011418698","https://openalex.org/W2013050062","https://openalex.org/W2016954422","https://openalex.org/W2017048459","https://openalex.org/W2019634859","https://openalex.org/W2033493433","https://openalex.org/W2033662966","https://openalex.org/W2034066116","https://openalex.org/W2036051703","https://openalex.org/W2036145467","https://openalex.org/W2036726267","https://openalex.org/W2037795767","https://openalex.org/W2039091678","https://openalex.org/W2044137812","https://openalex.org/W2044468084","https://openalex.org/W2044623634","https://openalex.org/W2045414097","https://openalex.org/W2045716051","https://openalex.org/W2046732260","https://openalex.org/W2047328154","https://openalex.org/W2048435193","https://openalex.org/W2051086599","https://openalex.org/W2051723119","https://openalex.org/W2053368008","https://openalex.org/W2054753506","https://openalex.org/W2061221231","https://openalex.org/W2063638829","https://openalex.org/W2064683986","https://openalex.org/W2064996887","https://openalex.org/W2065673659","https://openalex.org/W2067565974","https://openalex.org/W2068062922","https://openalex.org/W2069962655","https://openalex.org/W2071156517","https://openalex.org/W2071334120","https://openalex.org/W2071939615","https://openalex.org/W2072638800","https://openalex.org/W2076754896","https://openalex.org/W2081509710","https://openalex.org/W2081661931","https://openalex.org/W2085518524","https://openalex.org/W2089797759","https://openalex.org/W2090645860","https://openalex.org/W2093631510","https://openalex.org/W2098445519","https://openalex.org/W2100929136","https://openalex.org/W2103019815","https://openalex.org/W2105035735","https://openalex.org/W2105563190","https://openalex.org/W2106022949","https://openalex.org/W2107507666","https://openalex.org/W2112008896","https://openalex.org/W2118841351","https://openalex.org/W2126189748","https://openalex.org/W2130441789","https://openalex.org/W2131391971","https://openalex.org/W2137478666","https://openalex.org/W2138535275","https://openalex.org/W2138850552","https://openalex.org/W2140509484","https://openalex.org/W2144734201","https://openalex.org/W2145993448","https://openalex.org/W2152090288","https://openalex.org/W2152255690","https://openalex.org/W2156069194","https://openalex.org/W2156261151","https://openalex.org/W2159726703","https://openalex.org/W2162816987","https://openalex.org/W2163239509","https://openalex.org/W2164826175","https://openalex.org/W2169510202","https://openalex.org/W2169802060","https://openalex.org/W2191356548","https://openalex.org/W2206687388","https://openalex.org/W2209187832","https://openalex.org/W2317197305","https://openalex.org/W2322912881","https://openalex.org/W2328119063","https://openalex.org/W2337142316","https://openalex.org/W2394921548","https://openalex.org/W2407154151","https://openalex.org/W2418401855","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2000993232","https://openalex.org/W1998838849","https://openalex.org/W4231238871","https://openalex.org/W2317729153","https://openalex.org/W1981482014","https://openalex.org/W7161921547","https://openalex.org/W1996515613","https://openalex.org/W2410005013","https://openalex.org/W2011202194","https://openalex.org/W1991748853"],"abstract_inverted_index":{"In":[0,206],"recent":[1],"years":[2],"we":[3,211],"have":[4,196,250],"witnessed":[5],"a":[6,71,94,138],"growing":[7],"tendency":[8],"to":[9,42,120,234,249],"opt":[10],"for":[11,20,126,166,169,220],"the":[12,25,33,44,52,56,62,68,75,79,102,122,129,142,148,161,173,182,190,198,224,235,262,275],"use":[13,276],"of":[14,27,35,59,61,70,74,83,96,101,133,150,175,200,202,208,223,227,237,257,264,277],"dopamine":[15],"agonists":[16],"(DA)":[17],"as":[18,29,31],"treatment":[19,85,125],"Parkinson's":[21],"disease":[22],"(PD),":[23],"with":[24,78,88,146,204,274],"aim":[26],"delaying":[28],"far":[30],"possible":[32],"development":[34],"fluctuations":[36,243],"and":[37,49,81,99,131,163,168],"dyskinesias.":[38],"Yet,":[39],"levodopa":[40,84,118,232],"continues":[41,119],"be":[43,121],"most":[45,123],"effective":[46,124],"antiparkinson":[47],"drug":[48],"is":[50,116,156,164,216,260],"probably":[51],"one":[53],"that":[54,117,192,244],"improves":[55],"greatest":[57],"number":[58,149],"symptoms":[60,229],"disease.":[63],"This":[64],"article":[65,115],"reports":[66],"on":[67,172,189,197,254],"results":[69],"comprehensive":[72],"review":[73],"literature":[76],"dealing":[77],"benefits":[80],"risks":[82],"in":[86,113,141,159,181],"patients":[87,151,203,222],"PD":[89],"which":[90,185,270],"was":[91],"conducted":[92],"by":[93,231],"group":[95,143],"expert":[97],"neurologists":[98],"members":[100],"Spanish":[103],"Neurology":[104],"Society's":[105],"Movement":[106],"Disorder":[107],"Group.":[108],"The":[109],"main":[110],"conclusion":[111],"reached":[112],"this":[114],"PD.":[127,205],"Although":[128],"risk":[130],"incidence":[132],"developing":[134,238,266],"dyskinesias":[135,155,239],"remains":[136],"at":[137],"lower":[139],"level":[140],"initially":[144],"treated":[145],"DA,":[147],"who":[152],"develop":[153],"disabling":[154],"very":[157],"low":[158],"all":[160],"studies":[162],"similar":[165,180],"DA":[167],"levodopa.":[170],"Scores":[171],"quality":[174,199,256],"life":[176,201],"scales":[177],"are":[178,245,271],"also":[179,261],"two":[183],"groups,":[184],"casts":[186],"some":[187],"doubt":[188],"impact":[191],"these":[193,209],"motor":[194,242],"complications":[195],"view":[207],"findings,":[210],"should":[212],"consider":[213],"whether":[214],"there":[215],"any":[217,251],"real":[218],"justification":[219],"depriving":[221],"good":[225],"control":[226],"their":[228,255,265],"offered":[230],"owing":[233],"fear":[236],"or":[240],"mild":[241],"not":[246],"really":[247],"going":[248],"negative":[252],"effect":[253],"life.":[258],"There":[259],"possibility":[263],"severe":[267],"side":[268],"effects,":[269],"more":[272],"frequent":[273],"DA.":[278]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}