{"id":"https://openalex.org/W2172423474","doi":"https://doi.org/10.1152/ajpregu.1990.259.1.r163","title":"Influence of increased metabolic rate on [13C]bicarbonate washout kinetics","display_name":"Influence of increased metabolic rate on [13C]bicarbonate washout kinetics","publication_year":1990,"publication_date":"1990-07-01","ids":{"openalex":"https://openalex.org/W2172423474","doi":"https://doi.org/10.1152/ajpregu.1990.259.1.r163","mag":"2172423474","pmid":"https://pubmed.ncbi.nlm.nih.gov/2115744"},"language":"en","primary_location":{"id":"doi:10.1152/ajpregu.1990.259.1.r163","doi":"https://doi.org/10.1152/ajpregu.1990.259.1.r163","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpregu.1990.259.1.r163","pdf_url":null,"source":{"id":"https://openalex.org/S59702976","display_name":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","issn_l":"0363-6119","issn":["0363-6119","1522-1490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://escholarship.org/uc/item/4gv0k2rw","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006547767","display_name":"Thomas Jackson Barstow","orcid":"https://orcid.org/0000-0001-8175-1778","observed_orcids":["https://orcid.org/0000-0001-8175-1778"]},"institutions":[{"id":"https://openalex.org/I4210165985","display_name":"Harbor\u2013UCLA Medical Center","ror":"https://ror.org/05h4zj272","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328359107","https://openalex.org/I4210165985"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T. J. Barstow","raw_affiliation_strings":["Department of Medicine, Harbor-UCLA Medical Center, Torrance90509"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Harbor-UCLA Medical Center, Torrance90509","institution_ids":["https://openalex.org/I4210165985"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024191718","display_name":"Dan Michael Cooper","orcid":"https://orcid.org/0000-0003-4022-0043","observed_orcids":["https://orcid.org/0000-0003-4022-0043"]},"institutions":[{"id":"https://openalex.org/I4210165985","display_name":"Harbor\u2013UCLA Medical Center","ror":"https://ror.org/05h4zj272","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328359107","https://openalex.org/I4210165985"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. M. Cooper","raw_affiliation_strings":["Department of Medicine, Harbor-UCLA Medical Center, Torrance90509"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Harbor-UCLA Medical Center, Torrance90509","institution_ids":["https://openalex.org/I4210165985"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061772385","display_name":"Eric M. Sobel","orcid":"https://orcid.org/0000-0002-1718-0031","observed_orcids":["https://orcid.org/0000-0002-1718-0031"]},"institutions":[{"id":"https://openalex.org/I4210165985","display_name":"Harbor\u2013UCLA Medical Center","ror":"https://ror.org/05h4zj272","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328359107","https://openalex.org/I4210165985"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E. M. Sobel","raw_affiliation_strings":["Department of Medicine, Harbor-UCLA Medical Center, Torrance90509"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Harbor-UCLA Medical Center, Torrance90509","institution_ids":["https://openalex.org/I4210165985"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113560220","display_name":"Elliot M. Landaw","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210165985","display_name":"Harbor\u2013UCLA Medical Center","ror":"https://ror.org/05h4zj272","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328359107","https://openalex.org/I4210165985"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E. M. Landaw","raw_affiliation_strings":["Department of Medicine, Harbor-UCLA Medical Center, Torrance90509"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Harbor-UCLA Medical Center, Torrance90509","institution_ids":["https://openalex.org/I4210165985"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111471664","display_name":"Samuel Epstein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210165985","display_name":"Harbor\u2013UCLA Medical Center","ror":"https://ror.org/05h4zj272","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328359107","https://openalex.org/I4210165985"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Epstein","raw_affiliation_strings":["Department of Medicine, Harbor-UCLA Medical Center, Torrance90509"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Harbor-UCLA Medical Center, Torrance90509","institution_ids":["https://openalex.org/I4210165985"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210165985"],"apc_list":null,"apc_paid":null,"fwci":1.9805,"has_fulltext":false,"cited_by_count":59,"citation_normalized_percentile":{"value":0.88088342,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"259","issue":"1","first_page":"R163","last_page":"R171"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12840","display_name":"Renal function and acid-base balance","score":0.006399999838322401,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12930","display_name":"Biomedical and Chemical Research","score":0.006200000178068876,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/co2-flux","display_name":"CO2 flux","score":0.6330000162124634},{"id":"https://openalex.org/keywords/metabolic-rate","display_name":"metabolic rate","score":0.8500000238418579},{"id":"https://openalex.org/keywords/exercise","display_name":"physical activity","score":0.902999997138977},{"id":"https://openalex.org/keywords/13co2","display_name":"13CO2","score":0.574999988079071},{"id":"https://openalex.org/keywords/co2-elimination","display_name":"carbon dioxide elimination","score":0.6520000100135803},{"id":"https://openalex.org/keywords/lactate-threshold","display_name":"lactate threshold","score":0.6589999794960022},{"id":"https://openalex.org/keywords/pulmonary-gas-exchange","display_name":"pulmonary gas exchange","score":0.36500000953674316},{"id":"https://openalex.org/keywords/label-recovery","display_name":"label recovery","score":0.46000000834465027}],"concepts":[{"id":"https://openalex.org/C71839028","wikidata":"https://www.wikidata.org/wiki/Q7972627","display_name":"Washout","level":2,"score":0.7600622177124023},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6393330693244934},{"id":"https://openalex.org/C2781112554","wikidata":"https://www.wikidata.org/wiki/Q409202","display_name":"Bicarbonate","level":2,"score":0.6310389041900635},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.42731550335884094},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.383217453956604},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.35391151905059814},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21985787153244019},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12611865997314453}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001639","descriptor_name":"Bicarbonates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001639","descriptor_name":"Bicarbonates","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D002247","descriptor_name":"Carbon Isotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008657","descriptor_name":"Metabolic Clearance Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015444","descriptor_name":"Exercise","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1152/ajpregu.1990.259.1.r163","doi":"https://doi.org/10.1152/ajpregu.1990.259.1.r163","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpregu.1990.259.1.r163","pdf_url":null,"source":{"id":"https://openalex.org/S59702976","display_name":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","issn_l":"0363-6119","issn":["0363-6119","1522-1490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","raw_type":"journal-article"},{"id":"pmid:2115744","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2115744","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of physiology","raw_type":"Journal Article"},{"id":"pmh:oai:authors.library.caltech.edu:47280","doi":null,"is_oa":false,"landing_page_url":"https://authors.library.caltech.edu/47280/","pdf_url":null,"source":{"id":"https://openalex.org/S4306402161","display_name":"CaltechAUTHORS (California Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I122411786","host_organization_name":"California Institute of Technology","host_organization_lineage":["https://openalex.org/I122411786"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:escholarship.org/ark:/13030/qt4gv0k2rw","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/4gv0k2rw","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The American journal of physiology, vol 259, iss 1 Pt 2","raw_type":"article"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt4gv0k2rw","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/4gv0k2rw","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"American Journal of Physiology, vol 259, iss 1","raw_type":"article"},{"id":"pmh:qt4gv0k2rw","doi":null,"is_oa":true,"landing_page_url":"http://www.escholarship.org/uc/item/4gv0k2rw","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Barstow, TJ; Cooper, DM; Sobel, EM; Landaw, EM; & Epstein, S. (1990). Influence of increased metabolic rate on [13C]bicarbonate washout kinetics.. The American journal of physiology, 259(1 Pt 2), R163 - R171. doi: 10.1152/ajpregu.1990.259.1.r163. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4gv0k2rw","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:escholarship.org/ark:/13030/qt4gv0k2rw","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/4gv0k2rw","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The American journal of physiology, vol 259, iss 1 Pt 2","raw_type":"article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1466072718","display_name":"COUPLING OF EXTERNAL TO CELLULAR RESPIRATION","funder_award_id":"R01HL011907","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2759011702","display_name":null,"funder_award_id":"T32-DK-07461-04","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G5546215426","display_name":"NUTRITION AND METABOLISM","funder_award_id":"T32DK007461","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G9000898870","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA016042","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2256995348","https://openalex.org/W2079089161","https://openalex.org/W2019607609","https://openalex.org/W2198175569","https://openalex.org/W2038543012","https://openalex.org/W2076490466","https://openalex.org/W2051919823","https://openalex.org/W1997040267","https://openalex.org/W2014018900","https://openalex.org/W1597486735"],"abstract_inverted_index":{"The":[0,72,126],"effect":[1],"of":[2,10,38,49,65,74,82,107,128,166,173,243],"changes":[3,252],"in":[4,17,29,84,98,142,175,234,253],"metabolic":[5,99,227,254],"rate":[6,100,255],"on":[7],"the":[8,18,50,66,80,102,134,147,171,176,221,235,240],"dynamics":[9,28,242],"CO2":[11,27,129,174,244],"exchange":[12,213],"among":[13],"its":[14],"various":[15],"compartments":[16],"human":[19],"body":[20],"is":[21],"not":[22,200],"well":[23,78],"understood.":[24],"We":[25,237],"examined":[26],"six":[30],"healthy":[31],"male":[32],"subjects":[33],"using":[34],"an":[35],"intravenous":[36],"bolus":[37],"[13C]bicarbonate.":[39],"Subjects":[40],"were":[41],"studied":[42],"while":[43],"resting,":[44],"during":[45,61,91,113,117],"light":[46,118,184],"exercise":[47,63,93,103,121,185,205],"[50%":[48],"lactate":[51],"threshold":[52],"(LT),":[53],"3-4":[54],"times":[55,69],"resting":[56,70],"O2":[57],"uptake":[58],"(VO2)],":[59],"and":[60,90,119,137,216,246],"moderate":[62,120,204],"(95%":[64],"LT,":[67],"6":[68],"VO2).":[71],"sum":[73],"three":[75],"exponential":[76],"terms":[77],"described":[79],"washout":[81,135],"13CO2":[83],"exhaled":[85],"breath":[86,152,154],"both":[87],"at":[88],"rest":[89,114,182],"each":[92],"level":[94],"despite":[95],"substantial":[96],"increases":[97],"accompanying":[101],"studies.":[104],"Average":[105],"recovery":[106,140],"13C":[108],"label":[109],"rose":[110],"from":[111,133,181,220],"67%":[112],"to":[115,183,189,224,251],"80%":[116],"(P":[122],"less":[123,195],"than":[124,196],"0.01).":[125],"estimate":[127],"elimination":[130],"(VCO2)":[131],"calculated":[132],"parameters":[136],"corrected":[138],"for":[139,159,212,217],"was":[141,231],"very":[143,249],"good":[144],"agreement":[145],"with":[146,203,226],"VCO2":[148,160],"directly":[149],"measured":[150],"simultaneously":[151],"by":[153,257],"(r":[155],"=":[156,161],"0.993,":[157],"SE":[158],"0.079":[162],"l/min).":[163],"By":[164],"use":[165],"a":[167],"three-compartment":[168],"mammillary":[169],"model,":[170],"quantity":[172],"central":[177],"pool":[178],"(Q1)":[179],"doubled":[180],"(233":[186],"+/-":[187,191,207],"60":[188],"479":[190],"76":[192],"mmol,":[193],"P":[194],"0.01)":[197],"but":[198,229],"did":[199],"change":[201],"further":[202],"(458":[206],"74":[208],"mmol).":[209],"Rate":[210],"constants":[211],"between":[214],"pools":[215],"irreversible":[218],"loss":[219],"system":[222],"tended":[223],"increase":[225],"rate,":[228],"there":[230],"large":[232],"variation":[233],"responses.":[236],"conclude":[238],"that":[239],"compartmental":[241],"transport":[245],"storage":[247],"are":[248],"sensitive":[250],"induced":[256],"exercise.":[258]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}