{"id":"https://openalex.org/W2172297508","doi":null,"title":"Non-adherence to anti-TB drugs among TB/HIV co-infected patients in Mbarara Hospital Uganda: prevalence and associated factors.","display_name":"Non-adherence to anti-TB drugs among TB/HIV co-infected patients in Mbarara Hospital Uganda: prevalence and associated factors.","publication_year":2009,"publication_date":"2009-08-01","ids":{"openalex":"https://openalex.org/W2172297508","mag":"2172297508","pmid":"https://pubmed.ncbi.nlm.nih.gov/20589161","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2890989"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2890989","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2890989","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Afr Health Sci","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2890989","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042549590","display_name":"Monica G Amuha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I72227227","display_name":"Makerere University","ror":"https://ror.org/03dmz0111","country_code":"UG","type":"education","lineage":["https://openalex.org/I72227227"]}],"countries":["UG"],"is_corresponding":false,"raw_author_name":"Monica G Amuha","raw_affiliation_strings":["Department of Pharmacy, Faculty of Medicine, Makerere University, Kampala, Uganda"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Faculty of Medicine, Makerere University, Kampala, Uganda","institution_ids":["https://openalex.org/I72227227"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042903186","display_name":"Paul Kutyabami","orcid":"https://orcid.org/0000-0002-7975-9778","observed_orcids":["https://orcid.org/0000-0002-7975-9778"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paul Kutyabami","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070817307","display_name":"Freddy Eric Kitutu","orcid":"https://orcid.org/0000-0003-2277-9572","observed_orcids":["https://orcid.org/0000-0003-2277-9572"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Freddy E Kitutu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003482484","display_name":"Richard Odoi\u2010Adome","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Richard Odoi-Adome","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5014308193","display_name":"Joan Nakayaga Kalyango","orcid":"https://orcid.org/0000-0001-5113-2909","observed_orcids":["https://orcid.org/0000-0001-5113-2909"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joan N Kalyango","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.0395,"has_fulltext":true,"cited_by_count":71,"citation_normalized_percentile":{"value":0.90912013,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"9 Suppl 1","issue":null,"first_page":"S8","last_page":"15"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9545999765396118,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9545999765396118,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11620","display_name":"Medication Adherence and Compliance","score":0.027899999171495438,"subfield":{"id":"https://openalex.org/subfields/2714","display_name":"Family Practice"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.011599999852478504,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/treatment-nonadherence","display_name":"treatment non-adherence","score":0.7319999933242798},{"id":"https://openalex.org/keywords/tuberculosis","display_name":"tuberculosis","score":0.8069999814033508},{"id":"https://openalex.org/keywords/hiv-coinfection","display_name":"HIV coinfection","score":0.8379999995231628},{"id":"https://openalex.org/keywords/antituberculosis-drugs","display_name":"antitubercular agents","score":0.8690000176429749},{"id":"https://openalex.org/keywords/multidrug-resistant-tuberculosis","display_name":"multidrug-resistant tuberculosis","score":0.777999997138977},{"id":"https://openalex.org/keywords/pill-burden","display_name":"medication burden","score":0.6019999980926514},{"id":"https://openalex.org/keywords/alcohol-consumption","display_name":"alcohol consumption","score":0.8140000104904175},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.9670000076293945},{"id":"https://openalex.org/keywords/antiretroviral-therapy","display_name":"antiretroviral therapy","score":0.9990000128746033}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9491327404975891},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.6962841153144836},{"id":"https://openalex.org/C81603835","wikidata":"https://www.wikidata.org/wiki/Q3457430","display_name":"Pill","level":2,"score":0.5817844271659851},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.5513399839401245},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.5405714511871338},{"id":"https://openalex.org/C142052008","wikidata":"https://www.wikidata.org/wiki/Q954027","display_name":"Cross-sectional study","level":2,"score":0.5105510950088501},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.41692763566970825},{"id":"https://openalex.org/C3018553135","wikidata":"https://www.wikidata.org/wiki/Q67004728","display_name":"Medication adherence","level":2,"score":0.4133097231388092},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3593549430370331},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.3569898009300232},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.13925787806510925},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.07943177223205566},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000995","descriptor_name":"Antitubercular Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007722","descriptor_name":"Health Knowledge, Attitudes, Practice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010349","descriptor_name":"Patient Compliance","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D010349","descriptor_name":"Patient Compliance","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D012959","descriptor_name":"Socioeconomic Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014397","descriptor_name":"Tuberculosis, Pulmonary","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D014397","descriptor_name":"Tuberculosis, Pulmonary","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D014397","descriptor_name":"Tuberculosis, Pulmonary","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D014454","descriptor_name":"Uganda","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017088","descriptor_name":"AIDS-Related Opportunistic Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D017088","descriptor_name":"AIDS-Related Opportunistic Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D017088","descriptor_name":"AIDS-Related Opportunistic Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:2890989","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2890989","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Afr Health Sci","raw_type":"Text"},{"id":"pmh:oai:ajol.info:article/47806","doi":null,"is_oa":false,"landing_page_url":"https://www.ajol.info/index.php/ahs/article/view/47806","pdf_url":null,"source":{"id":"https://openalex.org/S167982310","display_name":"African Health Sciences","issn_l":"1680-6905","issn":["1680-6905","1729-0503"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jpps-2","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311036","host_organization_name":"Makerere University","host_organization_lineage":["https://openalex.org/P4310311036"],"host_organization_lineage_names":["Makerere University"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"1680-6905","raw_type":"info:eu-repo/semantics/article"},{"id":"pmid:20589161","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20589161","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"African health sciences","raw_type":"Journal Article"},{"id":"pmh:cria:bioline:hs:hs09024","doi":null,"is_oa":true,"landing_page_url":"http://www.bioline.org.br/abstract?id=hs09024","pdf_url":"http://www.bioline.org.br/abstract?id=hs09024","source":{"id":"https://openalex.org/S4306402188","display_name":"Bioline International (Bioline International)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"African Health Sciences (ISSN: 1680-6905) Vol 9 Num s1","raw_type":"AA"},{"id":"pmh:oai:utoronto.scholaris.ca:1807/50788","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/50788","pdf_url":"https://utoronto.scholaris.ca/bitstreams/2c535b60-dafc-464a-beb6-8fdf0ba90299/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"mag:2172297508","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20589161","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2890989","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2890989","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Afr Health Sci","raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2172297508.pdf","grobid_xml":"https://content.openalex.org/works/W2172297508.grobid-xml"},"referenced_works_count":16,"referenced_works":["https://openalex.org/W182865260","https://openalex.org/W183688999","https://openalex.org/W1607190847","https://openalex.org/W2006200870","https://openalex.org/W2021702829","https://openalex.org/W2072239732","https://openalex.org/W2073177078","https://openalex.org/W2074448530","https://openalex.org/W2090007886","https://openalex.org/W2090901804","https://openalex.org/W2127367771","https://openalex.org/W2129212659","https://openalex.org/W2154741117","https://openalex.org/W2271158049","https://openalex.org/W2272523073","https://openalex.org/W2505191766"],"related_works":["https://openalex.org/W7039962328","https://openalex.org/W7162245315","https://openalex.org/W2326194153","https://openalex.org/W4386745475","https://openalex.org/W7097781289","https://openalex.org/W2885895650","https://openalex.org/W2472153612","https://openalex.org/W2486280420","https://openalex.org/W7214121911","https://openalex.org/W2114708677"],"abstract_inverted_index":{"BACKGROUND:":[0],"Non-adherence":[1],"to":[2,8,71,103,110,122,164,232,254],"treatment":[3,228],"remains":[4],"a":[5,36,118,145],"major":[6],"obstacle":[7],"efficient":[9],"tuberculosis":[10],"control":[11],"in":[12,56,59,78,98],"developing":[13],"countries.":[14],"The":[15,171,214],"dual":[16],"infection":[17],"of":[18,27,38,46,173,183,207,216,226],"Tuberculosis":[19],"and":[20,31,48,66,87,148,200,211,244],"HIV":[21],"presents":[22],"further":[23],"adherence":[24],"problems":[25],"because":[26],"high":[28],"pill":[29],"burden":[30],"adverse":[32],"effects.":[33],"This":[34],"poses":[35],"risk":[37],"increased":[39],"multi-drug":[40],"resistant":[41],"TB.":[42],"However,":[43],"the":[44,64,123,184,203,208],"prevalence":[45,65,172,215],"non-adherence":[47,70,174,191,217],"its":[49],"associated":[50,68,167,189],"factors":[51,67,166],"have":[52],"not":[53,246],"been":[54],"studied":[55],"these":[57],"patients":[58,77,126,239],"Uganda.":[60],"OBJECTIVES:":[61],"To":[62],"determine":[63,165],"with":[69,85,168,190,252],"anti-TB":[72],"drugs":[73],"among":[74,94],"TB/HIV":[75,95],"co-infected":[76,96],"Mbarara":[79,99],"hospital.":[80],"METHODS:":[81],"A":[82],"cross-sectional":[83],"study":[84],"qualitative":[86],"quantitative":[88],"data":[89,137,153],"collection":[90],"methods":[91],"was":[92,108,115,129,138,149,154,162,175,187,218],"conducted":[93],"adults":[97],"hospital":[100],"from":[101],"January":[102],"March":[104],"2008.":[105],"Consecutive":[106],"sampling":[107],"used":[109,163],"select":[111],"140":[112],"participants.":[113],"Adherence":[114],"assessed":[116],"over":[117],"5-day":[119],"period":[120],"prior":[121],"interview":[124],"using":[125,131,144,156],"self-reports.":[127],"Data":[128],"collected":[130,139],"an":[132],"interviewer":[133],"administered":[134],"questionnaire.":[135],"Qualitative":[136],"through":[140],"key":[141],"informant":[142],"interviews":[143],"topic":[146],"guide":[147],"analyzed":[150,155],"manually.":[151],"Quantitative":[152],"STATA":[157],"version":[158],"8.":[159],"Logistic":[160],"regression":[161],"nonadherence.":[169],"RESULTS:":[170],"25%":[176],"(95%":[177],"CI=17.8-32%).":[178],"Being":[179],"on":[180,197,223,247],"continuous":[181,224],"phase":[182,225],"TB":[185,209,227],"regimen":[186,210],"significantly":[188],"(OR=6.24,":[192],"p<0.001).":[193],"Alcohol":[194],"consumption,":[195],"being":[196],"antiretroviral":[198],"therapy":[199],"smoking":[201],"confounded":[202],"relationship":[204],"between":[205],"stage":[206],"non-adherence.":[212],"CONCLUSION:":[213],"high.":[219],"Patients":[220],"that":[221,240],"are":[222],"should":[229,249],"be":[230,250],"supported":[231],"continue":[233],"taking":[234],"their":[235],"drugs.":[236],"In":[237],"addition,":[238],"drink":[241],"alcohol;":[242],"smoke":[243],"those":[245],"ART":[248],"targeted":[251],"interventions":[253],"improve":[255],"adherence.":[256]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":9}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}