{"id":"https://openalex.org/W21722085","doi":null,"title":"Mechanical effects of degeneration in lumbar intervertebral discs","display_name":"Mechanical effects of degeneration in lumbar intervertebral discs","publication_year":2002,"publication_date":"2002-01-01","ids":{"openalex":"https://openalex.org/W21722085","mag":"21722085"},"language":"en","primary_location":{"id":"mag:21722085","doi":null,"is_oa":false,"landing_page_url":"https://eprints.qut.edu.au/15781/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062577885","display_name":"Rosemary E. Thompson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"R. E. Thompson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5062577885"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10238","display_name":"Spine and Intervertebral Disc Pathology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10238","display_name":"Spine and Intervertebral Disc Pathology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10084","display_name":"Musculoskeletal pain and rehabilitation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3612","display_name":"Physical Therapy, Sports Therapy and Rehabilitation"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10776","display_name":"Spinal Fractures and Fixation Techniques","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lumbar-disc-degeneration","display_name":"lumbar disc degeneration","score":0.9549999833106995},{"id":"https://openalex.org/keywords/low-back-pain","display_name":"low back pain","score":0.7429999709129333},{"id":"https://openalex.org/keywords/neutral-zone","display_name":"neutral zone","score":0.6259999871253967},{"id":"https://openalex.org/keywords/disc-height","display_name":"disc height","score":0.7860000133514404},{"id":"https://openalex.org/keywords/flexion-extension","display_name":"flexion-extension","score":0.5120000243186951},{"id":"https://openalex.org/keywords/spine-kinematics","display_name":"spinal kinematics","score":0.6110000014305115},{"id":"https://openalex.org/keywords/intervertebral-disc-lesions","display_name":"intervertebral disc lesions","score":0.7279999852180481},{"id":"https://openalex.org/keywords/spine-stability","display_name":"spinal stability","score":0.382999986410141}],"concepts":[{"id":"https://openalex.org/C39920418","wikidata":"https://www.wikidata.org/wiki/Q11476","display_name":"Kinematics","level":2,"score":0.7372754812240601},{"id":"https://openalex.org/C44575665","wikidata":"https://www.wikidata.org/wiki/Q1293405","display_name":"Lumbar","level":2,"score":0.5656549334526062},{"id":"https://openalex.org/C170700871","wikidata":"https://www.wikidata.org/wiki/Q193378","display_name":"Biomechanics","level":2,"score":0.5489715337753296},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.5402159094810486},{"id":"https://openalex.org/C2780907711","wikidata":"https://www.wikidata.org/wiki/Q852163","display_name":"Low back pain","level":3,"score":0.5178649425506592},{"id":"https://openalex.org/C2777755357","wikidata":"https://www.wikidata.org/wiki/Q502781","display_name":"Intervertebral disc","level":2,"score":0.5164535045623779},{"id":"https://openalex.org/C2776501849","wikidata":"https://www.wikidata.org/wiki/Q5781808","display_name":"Back pain","level":3,"score":0.5036844611167908},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.44033390283584595},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.35464543104171753},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.3520194888114929},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.234665185213089},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.20529603958129883},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.07978621125221252},{"id":"https://openalex.org/C74650414","wikidata":"https://www.wikidata.org/wiki/Q11397","display_name":"Classical mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:21722085","doi":null,"is_oa":false,"landing_page_url":"https://eprints.qut.edu.au/15781/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1592354153","https://openalex.org/W7044305613","https://openalex.org/W6991861982","https://openalex.org/W2324525358","https://openalex.org/W2192979377","https://openalex.org/W2073244162","https://openalex.org/W7039433501","https://openalex.org/W2153617187","https://openalex.org/W2626676007","https://openalex.org/W2336520601"],"abstract_inverted_index":{"Lower":[0],"back":[1,20,45,75],"injuries":[2],"are":[3,528],"an":[4,726,759],"illness":[5],"which":[6],"plague":[7],"our":[8],"society.":[9],"Although":[11],"almost":[12],"everyone":[13],"will":[14,793],"experience":[15],"some":[16],"form":[17],"of":[18,43,61,68,119,127,138,152,185,199,202,218,256,259,272,281,302,313,323,403,420,427,446,460,484,489,507,514,537,548,566,578,602,678,693,699,712,732,774,782,790,796],"lower":[19],"pain":[21,46],"in":[22,95,231,262,276,320,360,370,450,466,481,497,511,636,655,746],"his":[23],"or":[24,599],"her":[25],"lifetime,":[26],"it":[27,54,86],"is":[28,32,47,55,80,87,431],"a":[29,81,144,160,167,200,287,300,306,314,321,404,508,688,705],"sickness":[30],"that":[31,71,98,253,328,359,412,521,751,787],"poorly":[33],"understood,":[34],"calling":[35],"for":[36,289,388,661],"new":[37],"and":[38,64,85,129,213,311,383,503,554,561,584,621,658,667,703,800],"innovative":[39],"research.":[40],"Much":[42],"this":[44,139,177,192,366,482,685,765],"attributed":[48],"to":[49,57,74,90,114,142,148,195,214,269,285,299,305,348,358,442,570,575,606,645,742,753,778],"mechanical":[50,66,233,354,373,535,564,730],"factors.":[51],"Hence,":[53],"important":[56],"understand":[58],"the":[59,62,65,116,150,181,186,197,210,216,223,241,257,260,264,273,335,338,350,371,381,397,401,414,418,425,428,444,447,479,490,494,505,525,529,563,567,571,576,579,591,596,600,603,614,623,628,647,652,676,695,700,709,723,729,733,754,772,775,788],"mechanics":[60,93,258,711],"spine":[63,79,261,480,702],"effects":[67,536],"degenerative":[69,803],"changes":[70],"may":[72,757],"lead":[73],"pain.":[76],"The":[78,135,293,487,534,737],"complex":[82],"three-dimensional":[83,183,697,710],"structure":[84,761],"therefore":[88],"necessary":[89],"study":[91],"its":[92],"with":[94,166,365,396],"vitro":[96,232],"tests":[97,174,234,249,374],"replicate":[99],"physiological":[100],"movements":[101],"as":[102,104,122,209,417],"closely":[103],"possible.":[105],"Traditional":[107],"spinal":[108,205,236,421,451,468,475,755,798],"testing":[109,146,154,243,355,690],"machines":[110],"have":[111,124],"been":[112],"unable":[113],"simulate":[115,180],"kinematic":[117],"behaviour":[118],"intervertebral":[120,224,265,538,559,597,629,653,679,713,776],"joints":[121,492,527],"they":[123],"limited":[125],"degrees":[126,463,502,620],"freedom":[128],"cannot":[130],"produce":[131,758,794],"dynamic":[132,182],"motion.":[133,607,681,783],"first":[136],"aim":[137],"research":[140,193,686],"was":[141,283,318,356,410,440,464,717,740],"commission":[143],"robotic":[145,242,398,689],"facility":[147,158,178,399,691],"overcome":[149],"limitations":[151],"traditional":[153],"machines.":[155],"This":[157,438,519,749,785],"incorporated":[159],"six":[161,168],"degree-of-freedom":[162],"(DOF)":[163],"robot":[164],"arm":[165],"DOF":[169],"force":[170],"transducer.":[171],"Mechanical":[173],"performed":[175,239,284,392,718],"on":[176,235,378,393,590,719],"could":[179],"kinematics":[184,698],"lumbar":[187,701],"spine.":[188,735],"In":[190,363,683],"addition,":[191],"aimed":[194],"assess":[196],"existence":[198,402],"region":[201,419,483],"laxity":[203],"during":[204,353,453,471,522,634,762],"joint":[206,422,569],"motion":[207,452,469],"defined":[208,413],"Neutral":[211,405,415,448,458,495,509,615,738,766],"Zone,":[212],"determine":[215,286,443],"effect":[217,589],"specific":[219],"lesions":[220,540,641,672,770,792],"introduced":[221],"into":[222,557,708,728],"disc.":[225],"To":[227,246],"investigate":[228],"these":[229,248,523],"aims,":[230],"specimens":[237,344,368],"were":[238,254,329,375,541,642],"using":[240],"facility.":[244],"ensure":[247,349],"produced":[250,337],"experimental":[251],"results":[252],"indicative":[255],"life,":[263],"disc":[266,274,295,351,539,598,630,654,680,777],"height":[267,275,296,352],"had":[268,587],"be":[270],"representative":[271],"life.":[277,361],"A":[279,408,457],"set":[280],"experiments":[282],"method":[288],"ensuring":[290],"this.":[291],"post-mortem":[294],"change":[297],"due":[298],"period":[301],"time":[303],"exposed":[304],"moist":[307],"environment,":[308],"freezing,":[309],"defrosting":[310],"application":[312],"constant":[315],"compressive":[316],"load":[317],"documented":[319],"group":[322],"sheep":[324,394,558,720],"spines.":[325],"Specimens":[327],"frozen":[330,376,385],"immediately":[331,377],"upon":[332],"removal":[333,379,488],"from":[334,380,435],"body":[336,382],"most":[339],"predictable":[340],"results.":[341],"These":[343],"required":[345,387],"no":[346,588],"preloading":[347],"similar":[357],"accordance":[364],"result,":[367],"used":[369,441],"ensuing":[372],"stored":[384],"until":[386],"testing.":[389],"Tests":[391],"spines":[395],"verified":[400],"Zone.":[406,767],"criterion":[409],"determined":[411],"Zone":[416,449,459,496,510,616,739],"rotation":[423,513,660],"where":[424],"gradient":[426],"load/deformation":[429],"curve":[430],"within":[432,764],"+/-0.5":[433],"dNm/degree":[434],"zero.":[436],"definition":[439],"extent":[445],"different":[454],"movements.":[455],"approximately":[461,500,515,618,632,665],"four":[462],"found":[465,644],"intact":[467],"segments":[470],"flexion/extension.":[472,747],"Only":[474],"musculature":[476],"can":[477],"stabilise":[478],"rotation.":[485],"zygapophysial":[491,526],"increased":[493,613],"flexion/extension":[498,763],"by":[499,543,595,617,627,631,651,664],"two":[501],"caused":[504],"appearance":[506],"axial":[512,659],"one":[516],"degree.":[517],"suggests":[520,786],"motions,":[524],"main":[530],"passive":[531],"stabilisers.":[532],"examined":[542],"experimentally":[544],"introducing":[545],"three":[546],"types":[547],"tears":[549,553,583,586],"(rim":[550],"lesions,":[551],"radial":[552],"concentric":[555,585],"tears)":[556],"discs":[560],"comparing":[562],"response":[565,573,605,731],"injured":[568],"joint's":[572,604],"prior":[574],"creation":[577],"lesions.":[580],"Radial":[582],"maximum":[592,624,648],"moments":[593],"resisted":[594,626,650],"hysteresis":[601,677],"An":[609],"anterior":[610],"rim":[611,791],"lesion":[612],"1.5":[619],"reduced":[622],"moment":[625,649],"20%":[633],"extension":[635],"L1/L2":[637],"specimens.":[638],"Rim":[640,671,769],"also":[643],"reduce":[646,771],"lateral":[656],"bending":[657],"all":[662,780],"levels":[663],"15%":[666],"25%":[668],"respectively.":[669],"did":[673],"not":[674],"affect":[675],"summary,":[684],"commissioned":[687],"capable":[692],"simulating":[694],"dynamic,":[696],"provided":[704],"unique":[706],"insight":[707,727],"joints.":[714],"Testing":[716],"joints,":[721],"however":[722],"outcomes":[724],"provide":[725],"human":[734],"shown":[741],"exist":[743],"but":[744],"only":[745],"implies":[750],"damage":[752],"muscles":[756],"unstable":[760],"ability":[773],"resist":[779],"modes":[781],"presence":[789],"overloading":[795],"other":[797],"elements":[799],"instigate":[801],"progressive":[802],"changes.":[804]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}