{"id":"https://openalex.org/W2171945138","doi":"https://doi.org/10.1007/978-3-642-77950-3_17","title":"Selection of Functional RNA and DNA Molecules from Randomized Sequences","display_name":"Selection of Functional RNA and DNA Molecules from Randomized Sequences","publication_year":1993,"publication_date":"1993-01-01","ids":{"openalex":"https://openalex.org/W2171945138","doi":"https://doi.org/10.1007/978-3-642-77950-3_17","mag":"2171945138"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-642-77950-3_17","doi":"https://doi.org/10.1007/978-3-642-77950-3_17","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-77950-3_17","pdf_url":null,"source":{"id":"https://openalex.org/S4210194239","display_name":"Nucleic acids and molecular biology","issn_l":"0933-1891","issn":["0933-1891","1869-2486"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids and Molecular Biology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2485099114","display_name":"Nucleic Acids and Molecular Biology"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055435399","display_name":"Michael Famulok","orcid":"https://orcid.org/0000-0001-5878-6577","observed_orcids":["https://orcid.org/0000-0001-5878-6577"]},"institutions":[{"id":"https://openalex.org/I149899117","display_name":"Max Planck Society","ror":"https://ror.org/01hhn8329","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I149899117"]},{"id":"https://openalex.org/I4210150093","display_name":"Max Planck Institute of Biochemistry","ror":"https://ror.org/04py35477","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210150093"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. Famulok","raw_affiliation_strings":["Institut f\u00fcr Biochemie Max-Planck- Institut f\u00fcr Biochemie, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, Martinsried, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Biochemie Max-Planck- Institut f\u00fcr Biochemie, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, Martinsried, Germany","institution_ids":["https://openalex.org/I149899117","https://openalex.org/I4210150093","https://openalex.org/I8204097"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023274897","display_name":"Jack W. Szostak","orcid":"https://orcid.org/0000-0003-4131-1203","observed_orcids":["https://orcid.org/0000-0003-4131-1203"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. W. Szostak","raw_affiliation_strings":["Department of Molecular Biology, Massachusetts General Hospital Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Massachusetts General Hospital Boston, USA","institution_ids":["https://openalex.org/I4210087915"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9518,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.88366013,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"271","last_page":"284"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.48190000653266907,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.48190000653266907,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.3037000000476837,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.06989999860525131,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/in-vitro-selection","display_name":"in vitro selection","score":0.9929999709129333},{"id":"https://openalex.org/keywords/selex","display_name":"SELEX","score":0.5640000104904175},{"id":"https://openalex.org/keywords/functional-rna","display_name":"functional RNA","score":0.5680000185966492},{"id":"https://openalex.org/keywords/ribozymes","display_name":"ribozymes","score":0.7279999852180481},{"id":"https://openalex.org/keywords/protein-nucleic-acid-binding","display_name":"protein-nucleic acid binding","score":0.8640000224113464},{"id":"https://openalex.org/keywords/substrate-specificity","display_name":"substrate specificity","score":0.777999997138977}],"concepts":[{"id":"https://openalex.org/C76346623","wikidata":"https://www.wikidata.org/wiki/Q205858","display_name":"Ribozyme","level":4,"score":0.8809670209884644},{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.8210481405258179},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.746159553527832},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.7135592699050903},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5349670052528381},{"id":"https://openalex.org/C126142528","wikidata":"https://www.wikidata.org/wiki/Q3771876","display_name":"Nucleic acid structure","level":4,"score":0.5042065382003784},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4702305495738983},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.44904837012290955},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40841156244277954},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.38888612389564514},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2621923089027405},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.17860054969787598}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-642-77950-3_17","doi":"https://doi.org/10.1007/978-3-642-77950-3_17","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-77950-3_17","pdf_url":null,"source":{"id":"https://openalex.org/S4210194239","display_name":"Nucleic acids and molecular biology","issn_l":"0933-1891","issn":["0933-1891","1869-2486"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids and Molecular Biology","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1785629757","https://openalex.org/W1963910866","https://openalex.org/W1964858690","https://openalex.org/W1973352434","https://openalex.org/W1988429255","https://openalex.org/W1989794771","https://openalex.org/W1999599455","https://openalex.org/W2004205790","https://openalex.org/W2009396937","https://openalex.org/W2017423606","https://openalex.org/W2019673480","https://openalex.org/W2020257254","https://openalex.org/W2022777131","https://openalex.org/W2027638512","https://openalex.org/W2030135048","https://openalex.org/W2034793893","https://openalex.org/W2036358440","https://openalex.org/W2039300520","https://openalex.org/W2047469022","https://openalex.org/W2050749062","https://openalex.org/W2058218887","https://openalex.org/W2077770365","https://openalex.org/W2079321730","https://openalex.org/W2086465539","https://openalex.org/W2104525153","https://openalex.org/W2118471196","https://openalex.org/W2125819516","https://openalex.org/W2133918133","https://openalex.org/W2313993185"],"related_works":["https://openalex.org/W2105859340","https://openalex.org/W2149005864","https://openalex.org/W2118471196","https://openalex.org/W2085400111","https://openalex.org/W1963910866","https://openalex.org/W2412182134","https://openalex.org/W4388227822","https://openalex.org/W63832282","https://openalex.org/W2033529393","https://openalex.org/W4388244359"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2016-06-24T00:00:00"}