{"id":"https://openalex.org/W2171512430","doi":"https://doi.org/10.1128/iai.00434-12","title":"Roles of Chaperone/Usher Pathways of Yersinia pestis in a Murine Model of Plague and Adhesion to Host Cells","display_name":"Roles of Chaperone/Usher Pathways of Yersinia pestis in a Murine Model of Plague and Adhesion to Host Cells","publication_year":2012,"publication_date":"2012-07-31","ids":{"openalex":"https://openalex.org/W2171512430","doi":"https://doi.org/10.1128/iai.00434-12","mag":"2171512430","pmid":"https://pubmed.ncbi.nlm.nih.gov/22851745","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3457579"},"language":"en","primary_location":{"id":"doi:10.1128/iai.00434-12","doi":"https://doi.org/10.1128/iai.00434-12","is_oa":false,"landing_page_url":"https://doi.org/10.1128/iai.00434-12","pdf_url":null,"source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/articles/PMC3457579","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073809565","display_name":"Matthew Hatkoff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew Hatkoff","raw_affiliation_strings":["Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, USA","Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, USA","institution_ids":["https://openalex.org/I59553526"]},{"raw_affiliation_string":"Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA","institution_ids":["https://openalex.org/I59553526"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034293585","display_name":"Lisa M. Runco","orcid":"https://orcid.org/0000-0002-5864-9027","observed_orcids":["https://orcid.org/0000-0002-5864-9027"]},"institutions":[{"id":"https://openalex.org/I4210104314","display_name":"New York Institute of Technology","ror":"https://ror.org/01bghzb51","country_code":"US","type":"education","lineage":["https://openalex.org/I4210104314"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lisa M. Runco","raw_affiliation_strings":["Department of Life Sciences, New York Institute of Technology, Old Westbury, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Sciences, New York Institute of Technology, Old Westbury, New York, USA","institution_ids":["https://openalex.org/I4210104314"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002237432","display_name":"C\u00e9line Pujol","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Celine Pujol","raw_affiliation_strings":["Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, USA","Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, USA","institution_ids":["https://openalex.org/I59553526"]},{"raw_affiliation_string":"Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA","institution_ids":["https://openalex.org/I59553526"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078984514","display_name":"Indralatha Jayatilaka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Indralatha Jayatilaka","raw_affiliation_strings":["Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, USA","Department of Pathology, Stony Brook University, Stony Brook, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, USA","institution_ids":["https://openalex.org/I59553526"]},{"raw_affiliation_string":"Department of Pathology, Stony Brook University, Stony Brook, New York, USA","institution_ids":["https://openalex.org/I59553526"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111886652","display_name":"Martha B. Furie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martha B. Furie","raw_affiliation_strings":["Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, USA","Department of Pathology, Stony Brook University, Stony Brook, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, USA","institution_ids":["https://openalex.org/I59553526"]},{"raw_affiliation_string":"Department of Pathology, Stony Brook University, Stony Brook, New York, USA","institution_ids":["https://openalex.org/I59553526"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013547809","display_name":"James B. Bliska","orcid":"https://orcid.org/0000-0002-6047-8837","observed_orcids":["https://orcid.org/0000-0002-6047-8837"]},"institutions":[{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James B. Bliska","raw_affiliation_strings":["Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, USA","Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, USA","institution_ids":["https://openalex.org/I59553526"]},{"raw_affiliation_string":"Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA","institution_ids":["https://openalex.org/I59553526"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039688220","display_name":"David G. Thanassi","orcid":"https://orcid.org/0000-0002-9798-9040","observed_orcids":["https://orcid.org/0000-0002-9798-9040"]},"institutions":[{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David G. Thanassi","raw_affiliation_strings":["Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, USA","Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, USA","institution_ids":["https://openalex.org/I59553526"]},{"raw_affiliation_string":"Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA","institution_ids":["https://openalex.org/I59553526"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3835,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.64867514,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"80","issue":"10","first_page":"3490","last_page":"3500"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12232","display_name":"Yersinia bacterium, plague, ectoparasites research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12232","display_name":"Yersinia bacterium, plague, ectoparasites research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11515","display_name":"Bacillus and Francisella bacterial research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/yersinia-pestis","display_name":"Yersinia pestis","score":1.0},{"id":"https://openalex.org/keywords/chaperone-usher-pathway","display_name":"chaperone-usher pathway","score":0.8999999761581421},{"id":"https://openalex.org/keywords/pneumonic-plague","display_name":"pneumonic plague","score":0.9449999928474426},{"id":"https://openalex.org/keywords/bubonic-plague","display_name":"bubonic plague","score":0.9990000128746033},{"id":"https://openalex.org/keywords/bacterial-adhesion-to-host-cells","display_name":"bacterial adhesion to host cells","score":0.7979999780654907},{"id":"https://openalex.org/keywords/attenuated-virulence","display_name":"virulence attenuation","score":0.7860000133514404},{"id":"https://openalex.org/keywords/macrophage-binding","display_name":"macrophage binding","score":0.8169999718666077}],"concepts":[{"id":"https://openalex.org/C2778222588","wikidata":"https://www.wikidata.org/wiki/Q153875","display_name":"Yersinia pestis","level":4,"score":0.972704291343689},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8367657661437988},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.8115835785865784},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6776748299598694},{"id":"https://openalex.org/C2775962898","wikidata":"https://www.wikidata.org/wiki/Q5073152","display_name":"Chaperone (clinical)","level":2,"score":0.5677451491355896},{"id":"https://openalex.org/C174832134","wikidata":"https://www.wikidata.org/wiki/Q934786","display_name":"Pilus","level":4,"score":0.5431113243103027},{"id":"https://openalex.org/C39103817","wikidata":"https://www.wikidata.org/wiki/Q1810775","display_name":"Fimbria","level":4,"score":0.5315905213356018},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.48905739188194275},{"id":"https://openalex.org/C136961756","wikidata":"https://www.wikidata.org/wiki/Q7431879","display_name":"Schneider 2 cells","level":5,"score":0.4607663154602051},{"id":"https://openalex.org/C179470777","wikidata":"https://www.wikidata.org/wiki/Q356661","display_name":"Bacterial adhesin","level":4,"score":0.4241585433483124},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.35552334785461426},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2395942509174347},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C166703698","wikidata":"https://www.wikidata.org/wiki/Q201993","display_name":"RNA interference","level":4,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001422","descriptor_name":"Bacterial Adhesion","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D001425","descriptor_name":"Bacterial Outer Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001425","descriptor_name":"Bacterial Outer Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010861","descriptor_name":"Fimbriae, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010930","descriptor_name":"Plague","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010930","descriptor_name":"Plague","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D015010","descriptor_name":"Yersinia pestis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015010","descriptor_name":"Yersinia pestis","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D015964","descriptor_name":"Gene Expression Regulation, Bacterial","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017353","descriptor_name":"Gene Deletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018832","descriptor_name":"Molecular Chaperones","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018832","descriptor_name":"Molecular Chaperones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1128/iai.00434-12","doi":"https://doi.org/10.1128/iai.00434-12","is_oa":false,"landing_page_url":"https://doi.org/10.1128/iai.00434-12","pdf_url":null,"source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2612100","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3457579","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3457579","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3457579","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infect Immun","raw_type":"Text"},{"id":"pmid:22851745","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22851745","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and immunity","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2612100","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3457579","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5683000087738037}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1851367982","display_name":null,"funder_award_id":"AI-055621","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G4030488714","display_name":"Molecular and Cell Biology of Infectious Diseases","funder_award_id":"T32AI007539","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G7149775273","display_name":"Agents of Bioterrorism: Pathogenesis and Host Defense","funder_award_id":"P01AI055621","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G8733888550","display_name":"Northeast Biodefense Center","funder_award_id":"U54AI057158","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320309652","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":81,"referenced_works":["https://openalex.org/W120336564","https://openalex.org/W1496206559","https://openalex.org/W1509406441","https://openalex.org/W1545356237","https://openalex.org/W1564219524","https://openalex.org/W1884874540","https://openalex.org/W1945326836","https://openalex.org/W1945764684","https://openalex.org/W1965202893","https://openalex.org/W1971359499","https://openalex.org/W1973125631","https://openalex.org/W1974760528","https://openalex.org/W1976548360","https://openalex.org/W1979429534","https://openalex.org/W1992035449","https://openalex.org/W2004583012","https://openalex.org/W2005473844","https://openalex.org/W2006130551","https://openalex.org/W2006678158","https://openalex.org/W2020057555","https://openalex.org/W2020615202","https://openalex.org/W2026267747","https://openalex.org/W2027229485","https://openalex.org/W2030424501","https://openalex.org/W2032092088","https://openalex.org/W2037689198","https://openalex.org/W2038663142","https://openalex.org/W2039935334","https://openalex.org/W2050868215","https://openalex.org/W2053934212","https://openalex.org/W2056778778","https://openalex.org/W2059276333","https://openalex.org/W2063789561","https://openalex.org/W2066892857","https://openalex.org/W2072617582","https://openalex.org/W2076959396","https://openalex.org/W2084807370","https://openalex.org/W2096812889","https://openalex.org/W2097891084","https://openalex.org/W2099432505","https://openalex.org/W2099893307","https://openalex.org/W2102249573","https://openalex.org/W2103466224","https://openalex.org/W2104135347","https://openalex.org/W2105005583","https://openalex.org/W2107156538","https://openalex.org/W2111198831","https://openalex.org/W2111205680","https://openalex.org/W2114678557","https://openalex.org/W2114816974","https://openalex.org/W2115332881","https://openalex.org/W2116137883","https://openalex.org/W2116513121","https://openalex.org/W2117675098","https://openalex.org/W2117816351","https://openalex.org/W2125677667","https://openalex.org/W2128537616","https://openalex.org/W2132091434","https://openalex.org/W2136799667","https://openalex.org/W2141261615","https://openalex.org/W2144244244","https://openalex.org/W2145912774","https://openalex.org/W2148853770","https://openalex.org/W2149027421","https://openalex.org/W2149120880","https://openalex.org/W2149461468","https://openalex.org/W2151294441","https://openalex.org/W2152811396","https://openalex.org/W2154275726","https://openalex.org/W2156691801","https://openalex.org/W2158369156","https://openalex.org/W2159138215","https://openalex.org/W2160502767","https://openalex.org/W2162083166","https://openalex.org/W2163173478","https://openalex.org/W2165811410","https://openalex.org/W2168057340","https://openalex.org/W2170233440","https://openalex.org/W2171454507","https://openalex.org/W2172237013","https://openalex.org/W2994270779"],"related_works":["https://openalex.org/W2527657537","https://openalex.org/W4301382898","https://openalex.org/W28751630","https://openalex.org/W2117816351","https://openalex.org/W2103466224","https://openalex.org/W2160469495","https://openalex.org/W2153900350","https://openalex.org/W4285752552","https://openalex.org/W1987645931","https://openalex.org/W192564777"],"abstract_inverted_index":{"Yersinia":[0],"pestis":[1,23,49,90,114,158,182,233],"and":[2,37,96,107,123,160,175,178,186,214],"many":[3],"other":[4],"Gram-negative":[5],"pathogenic":[6],"bacteria":[7],"use":[8],"the":[9,29,34,38,43,63,69,81,87,103,131,135,156,211,220,227,244],"chaperone/usher":[10],"(CU)":[11],"pathway":[12,200],"to":[13,130,164,190,192,194,206],"assemble":[14],"virulence-associated":[15],"surface":[16],"fibers":[17],"termed":[18],"pili":[19],"or":[20],"fimbriae.":[21],"Y.":[22,48,89,113,157,181,232],"has":[24],"two":[25],"well-characterized":[26],"CU":[27,53,91,119,183,229],"pathways:":[28],"caf":[30],"genes":[31,40,83],"coding":[32,41],"for":[33,42,84,127,146,204,243],"F1":[35],"capsule":[36],"psa":[39],"pH":[44],"6":[45],"antigen.":[46],"The":[47,93,208],"genome":[50],"contains":[51],"additional":[52,88,228],"pathways":[54,67,120,148,184,230],"that":[55,240],"are":[56,73,241],"capable":[57],"of":[58,65,71,86,141,155,219,226,231,246],"assembling":[59],"pilus":[60],"fibers,":[61],"but":[62,137],"roles":[64,145],"these":[66,147],"in":[68,80,102,118],"pathogenesis":[70,245],"plague":[72,110],"not":[74,138],"understood.":[75],"We":[76,152],"constructed":[77],"deletion":[78,98,162,222],"mutations":[79],"usher":[82,97,161,221],"six":[85],"pathways.":[92],"wild-type":[94],"(WT)":[95],"strains":[99,115,163],"were":[100,125,188],"compared":[101,129],"murine":[104,179],"bubonic":[105],"(subcutaneous)":[106],"pneumonic":[108,150],"(intranasal)":[109],"infection":[111],"models.":[112],"containing":[116],"deletions":[117],"y0348-0352,":[121],"y1858-1862,":[122],"y1869-1873":[124,201],"attenuated":[126],"virulence":[128,212],"WT":[132,159],"strain":[133],"by":[134],"intranasal,":[136],"subcutaneous,":[139],"routes":[140],"infection,":[142],"suggesting":[143],"specific":[144,203],"during":[149],"plague.":[151,247],"examined":[153],"binding":[154,205,217],"A549":[165],"human":[166,171,177],"lung":[167],"epithelial":[168,173],"cells,":[169,174],"HEp-2":[170],"cervical":[172],"primary":[176],"macrophages.":[180,207],"y0348-0352":[185],"y1858-1862":[187],"found":[189],"contribute":[191],"adhesion":[193],"all":[195],"host":[196,215,238],"cells":[197,239],"tested,":[198],"whereas":[199],"was":[202],"correlation":[209],"between":[210],"attenuation":[213],"cell":[216],"phenotypes":[218],"mutants":[223],"identifies":[224],"three":[225],"as":[234],"mediating":[235],"interactions":[236],"with":[237],"important":[242]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}