{"id":"https://openalex.org/W2171453333","doi":"https://doi.org/10.1128/jvi.02472-06","title":"Activated CD34-Derived Langerhans Cells Mediate Transinfection with Human Immunodeficiency Virus","display_name":"Activated CD34-Derived Langerhans Cells Mediate Transinfection with Human Immunodeficiency Virus","publication_year":2007,"publication_date":"2007-04-19","ids":{"openalex":"https://openalex.org/W2171453333","doi":"https://doi.org/10.1128/jvi.02472-06","mag":"2171453333","pmid":"https://pubmed.ncbi.nlm.nih.gov/17442711","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1933306"},"language":"en","primary_location":{"id":"doi:10.1128/jvi.02472-06","doi":"https://doi.org/10.1128/jvi.02472-06","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.02472-06","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1933306","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073649685","display_name":"Kelly M. Fahrbach","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kelly M. Fahrbach","raw_affiliation_strings":["Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611","; Department of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"; Department of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002356349","display_name":"Sheila M. Barry","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]},{"id":"https://openalex.org/I4210121331","display_name":"MatTek Corporation (United States)","ror":"https://ror.org/0305ndp35","country_code":"US","type":"company","lineage":["https://openalex.org/I4210121331"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sheila M. Barry","raw_affiliation_strings":["Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611","Department of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612","; and MatTek Corporation, 200 Homer Avenue, Ashland, Massachusetts 01721"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Department of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612","institution_ids":["https://openalex.org/I39422238"]},{"raw_affiliation_string":"; and MatTek Corporation, 200 Homer Avenue, Ashland, Massachusetts 01721","institution_ids":["https://openalex.org/I4210121331"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082282921","display_name":"Seyoum Ayehunie","orcid":"https://orcid.org/0000-0002-4365-5504","observed_orcids":["https://orcid.org/0000-0002-4365-5504"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I4210121331","display_name":"MatTek Corporation (United States)","ror":"https://ror.org/0305ndp35","country_code":"US","type":"company","lineage":["https://openalex.org/I4210121331"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Seyoum Ayehunie","raw_affiliation_strings":["MatTek Corporation, 200 Homer Avenue, Ashland, Massachusetts 01721","Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern Uni-versity, Ward 8-140, 303 E. Chicago Avenue, Chicago, IL 60611-3008","Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MatTek Corporation, 200 Homer Avenue, Ashland, Massachusetts 01721","institution_ids":["https://openalex.org/I4210121331"]},{"raw_affiliation_string":"Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern Uni-versity, Ward 8-140, 303 E. Chicago Avenue, Chicago, IL 60611-3008","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075701007","display_name":"Sarah D. Lamore","orcid":"https://orcid.org/0000-0002-5786-2766","observed_orcids":["https://orcid.org/0000-0002-5786-2766"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I4210121331","display_name":"MatTek Corporation (United States)","ror":"https://ror.org/0305ndp35","country_code":"US","type":"company","lineage":["https://openalex.org/I4210121331"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah Lamore","raw_affiliation_strings":["MatTek Corporation, 200 Homer Avenue, Ashland, Massachusetts 01721","Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern Uni-versity, Ward 8-140, 303 E. Chicago Avenue, Chicago, IL 60611-3008","Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MatTek Corporation, 200 Homer Avenue, Ashland, Massachusetts 01721","institution_ids":["https://openalex.org/I4210121331"]},{"raw_affiliation_string":"Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern Uni-versity, Ward 8-140, 303 E. Chicago Avenue, Chicago, IL 60611-3008","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072858660","display_name":"Mitchell Klausner","orcid":"https://orcid.org/0000-0003-0651-6895","observed_orcids":["https://orcid.org/0000-0003-0651-6895"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I4210121331","display_name":"MatTek Corporation (United States)","ror":"https://ror.org/0305ndp35","country_code":"US","type":"company","lineage":["https://openalex.org/I4210121331"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mitchell Klausner","raw_affiliation_strings":["MatTek Corporation, 200 Homer Avenue, Ashland, Massachusetts 01721","Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern Uni-versity, Ward 8-140, 303 E. Chicago Avenue, Chicago, IL 60611-3008","Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MatTek Corporation, 200 Homer Avenue, Ashland, Massachusetts 01721","institution_ids":["https://openalex.org/I4210121331"]},{"raw_affiliation_string":"Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern Uni-versity, Ward 8-140, 303 E. Chicago Avenue, Chicago, IL 60611-3008","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009527416","display_name":"Thomas J. Hope","orcid":"https://orcid.org/0000-0001-7183-8319","observed_orcids":["https://orcid.org/0000-0001-7183-8319"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Thomas J. Hope","raw_affiliation_strings":["Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611","; Department of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"; Department of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612","institution_ids":["https://openalex.org/I39422238"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5009527416"],"corresponding_institution_ids":["https://openalex.org/I111979921","https://openalex.org/I39422238"],"apc_list":null,"apc_paid":null,"fwci":5.8043,"has_fulltext":false,"cited_by_count":103,"citation_normalized_percentile":{"value":0.97133088,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"81","issue":"13","first_page":"6858","last_page":"6868"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/langerhans-cells","display_name":"Langerhans cells","score":0.9950000047683716},{"id":"https://openalex.org/keywords/tetraspanins","display_name":"tetraspanins","score":0.921999990940094},{"id":"https://openalex.org/keywords/langerin","display_name":"Langerin","score":0.9909999966621399},{"id":"https://openalex.org/keywords/cd1a","display_name":"CD1a","score":0.9900000095367432},{"id":"https://openalex.org/keywords/hiv-transmission","display_name":"HIV transmission","score":0.621999979019165},{"id":"https://openalex.org/keywords/sexually-transmitted-infections","display_name":"sexually transmitted infections","score":0.8659999966621399},{"id":"https://openalex.org/keywords/genital-tract-inflammation","display_name":"genital inflammation","score":0.7390000224113464}],"concepts":[{"id":"https://openalex.org/C119765067","wikidata":"https://www.wikidata.org/wiki/Q6485957","display_name":"Langerin","level":4,"score":0.964604377746582},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8350067734718323},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5909334421157837},{"id":"https://openalex.org/C2778379841","wikidata":"https://www.wikidata.org/wiki/Q1623344","display_name":"Langerhans cell","level":3,"score":0.5701314806938171},{"id":"https://openalex.org/C2778170410","wikidata":"https://www.wikidata.org/wiki/Q506253","display_name":"Dendritic cell","level":3,"score":0.5095539093017578},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.5064958333969116},{"id":"https://openalex.org/C10205521","wikidata":"https://www.wikidata.org/wiki/Q4035578","display_name":"CD34","level":3,"score":0.4743543863296509},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.45956164598464966},{"id":"https://openalex.org/C2781184567","wikidata":"https://www.wikidata.org/wiki/Q107244","display_name":"Monocyte","level":2,"score":0.44609808921813965},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3718832731246948},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.2269306480884552},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.18250206112861633}],"mesh":[{"descriptor_ui":"D000943","descriptor_name":"Antigens, Differentiation","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004817","descriptor_name":"Epidermis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004817","descriptor_name":"Epidermis","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D004817","descriptor_name":"Epidermis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D005835","descriptor_name":"Genitalia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005835","descriptor_name":"Genitalia","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007801","descriptor_name":"Langerhans Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007801","descriptor_name":"Langerhans Cells","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D007801","descriptor_name":"Langerhans Cells","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D009092","descriptor_name":"Mucous Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009092","descriptor_name":"Mucous Membrane","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D009092","descriptor_name":"Mucous Membrane","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000635","qualifier_name":"transmission","is_major_topic":true},{"descriptor_ui":"D015703","descriptor_name":"Antigens, CD","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018949","descriptor_name":"Antigens, CD1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018952","descriptor_name":"Antigens, CD34","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D037181","descriptor_name":"Lectins, C-Type","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D037241","descriptor_name":"Mannose-Binding Lectins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1128/jvi.02472-06","doi":"https://doi.org/10.1128/jvi.02472-06","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.02472-06","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1933306","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1933306","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},{"id":"pmid:17442711","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17442711","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of virology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1933306","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1933306","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.7799999713897705,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1256696250","display_name":"Cell Biology and HIV Entry","funder_award_id":"R01AI052051","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G857080793","display_name":"FEMALE GENITAL TRACT IN HIV PATHOGENESIS","funder_award_id":"P01HD040539","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G9000203049","display_name":null,"funder_award_id":"HD40539","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000351141","display_name":null,"funder_award_id":"AI052051","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W291482005","https://openalex.org/W1560080751","https://openalex.org/W1653335370","https://openalex.org/W1972524970","https://openalex.org/W1974692569","https://openalex.org/W1980272197","https://openalex.org/W1982769349","https://openalex.org/W2000093265","https://openalex.org/W2006370225","https://openalex.org/W2008595075","https://openalex.org/W2011103103","https://openalex.org/W2016599962","https://openalex.org/W2028603136","https://openalex.org/W2030232170","https://openalex.org/W2034498886","https://openalex.org/W2041361352","https://openalex.org/W2043152270","https://openalex.org/W2045971903","https://openalex.org/W2057284833","https://openalex.org/W2062561488","https://openalex.org/W2062736327","https://openalex.org/W2073273867","https://openalex.org/W2074673603","https://openalex.org/W2078843400","https://openalex.org/W2083889661","https://openalex.org/W2112517102","https://openalex.org/W2114726166","https://openalex.org/W2124377305","https://openalex.org/W2134206256","https://openalex.org/W2145289892","https://openalex.org/W2145359348","https://openalex.org/W2154892007","https://openalex.org/W2155085328","https://openalex.org/W2164359866","https://openalex.org/W2164610821","https://openalex.org/W2170880674","https://openalex.org/W2323319060"],"related_works":["https://openalex.org/W2066745695","https://openalex.org/W2950389326","https://openalex.org/W2030232170","https://openalex.org/W2049001072","https://openalex.org/W2012221307","https://openalex.org/W2116511434","https://openalex.org/W1998933853","https://openalex.org/W2000093265","https://openalex.org/W1984819838","https://openalex.org/W1653335370"],"abstract_inverted_index":{"Langerhans":[0],"cells":[1,8,26,50,120],"(LCs)":[2],"are":[3,22],"a":[4,115],"subset":[5],"of":[6,18,48,81,87,103,137],"dendritic":[7],"(DCs)":[9],"that":[10,38,62,78,88,96,108,133],"reside":[11],"within":[12,83],"epidermal":[13],"and":[14,74,95],"mucosal":[15],"tissue.":[16],"Because":[17],"their":[19],"location,":[20],"LCs":[21,39,84,110],"potentially":[23],"the":[24,46,69,79,100,104,122,138],"first":[25],"to":[27,68],"encounter":[28],"human":[29],"immunodeficiency":[30],"virus":[31],"(HIV)":[32],"during":[33],"sexual":[34],"transmission.":[35],"We":[36],"report":[37],"purified":[40],"from":[41],"CD34(+)-derived":[42],"DCs":[43,94],"can":[44,111],"facilitate":[45],"transinfection":[47,113],"target":[49],"but":[51],"only":[52],"after":[53],"activation.":[54],"Virions":[55],"were":[56],"observed":[57],"in":[58,66,91,121,125],"an":[59],"intracellular":[60],"compartment":[61],"contains":[63],"several":[64],"tetraspanins,":[65],"addition":[67],"unique":[70],"LC":[71],"markers":[72],"langerin":[73],"CD1a.":[75],"This":[76],"reveals":[77],"trafficking":[80],"HIV":[82,126],"is":[85],"reminiscent":[86],"which":[89],"occurs":[90],"mature":[92],"monocyte-derived":[93],"it":[97],"varies":[98],"with":[99,129],"activation":[101],"state":[102],"cell.":[105],"The":[106],"observation":[107],"activated":[109],"mediate":[112],"suggests":[114],"potential":[116],"role":[117],"for":[118],"these":[119],"known":[123],"increase":[124],"transmission":[127],"associated":[128],"sexually":[130],"transmitted":[131],"infections":[132],"would":[134],"cause":[135],"inflammation":[136],"genital":[139],"lining.":[140]},"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}