{"id":"https://openalex.org/W2171388116","doi":"https://doi.org/10.1021/cc049973b","title":"Parallel Solid-Phase Syntheses of 1,3,4-Thiadiazolium-2-Aminides","display_name":"Parallel Solid-Phase Syntheses of 1,3,4-Thiadiazolium-2-Aminides","publication_year":2004,"publication_date":"2004-08-27","ids":{"openalex":"https://openalex.org/W2171388116","doi":"https://doi.org/10.1021/cc049973b","mag":"2171388116","pmid":"https://pubmed.ncbi.nlm.nih.gov/15360209"},"language":"en","primary_location":{"id":"doi:10.1021/cc049973b","doi":"https://doi.org/10.1021/cc049973b","is_oa":false,"landing_page_url":"https://doi.org/10.1021/cc049973b","pdf_url":null,"source":{"id":"https://openalex.org/S4210175341","display_name":"Journal of Combinatorial Chemistry","issn_l":"1520-4766","issn":["1520-4766","1520-4774"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Combinatorial Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085527402","display_name":"Joseph C. Kappel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph C. Kappel","raw_affiliation_strings":["Department of Chemistry, University of Minnesota, 207 Pleasant Street S.E., Minneapolis, Minnesota 55455"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Minnesota, 207 Pleasant Street S.E., Minneapolis, Minnesota 55455","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042329839","display_name":"T. Scott Yokum","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T. Scott Yokum","raw_affiliation_strings":["Department of Chemistry, University of Minnesota, 207 Pleasant Street S.E., Minneapolis, Minnesota 55455"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Minnesota, 207 Pleasant Street S.E., Minneapolis, Minnesota 55455","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019782256","display_name":"George B\u00e1r\u00e1ny","orcid":"https://orcid.org/0000-0002-6373-2706","observed_orcids":["https://orcid.org/0000-0002-6373-2706"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George Barany","raw_affiliation_strings":["Department of Chemistry, University of Minnesota, 207 Pleasant Street S.E., Minneapolis, Minnesota 55455"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Minnesota, 207 Pleasant Street S.E., Minneapolis, Minnesota 55455","institution_ids":["https://openalex.org/I130238516"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I130238516"],"apc_list":null,"apc_paid":null,"fwci":1.2681,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.76822642,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"6","issue":"5","first_page":"746","last_page":"752"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12410","display_name":"Structural and Chemical Analysis of Organic and Inorganic Compounds","score":0.8676999807357788,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12410","display_name":"Structural and Chemical Analysis of Organic and Inorganic Compounds","score":0.8676999807357788,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.0868000015616417,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13304","display_name":"Synthesis and Reactivity of Sulfur-Containing Compounds","score":0.008700000122189522,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/solid-phase-synthesis","display_name":"solid-phase synthesis","score":0.9440000057220459},{"id":"https://openalex.org/keywords/parallel-synthesis","display_name":"parallel synthesis","score":0.9700000286102295},{"id":"https://openalex.org/keywords/combinatorial-chemistry","display_name":"combinatorial chemistry","score":0.7919999957084656},{"id":"https://openalex.org/keywords/thiosemicarbazide","display_name":"thiosemicarbazide","score":0.9509999752044678},{"id":"https://openalex.org/keywords/isothiocyanates","display_name":"isothiocyanates","score":0.800000011920929},{"id":"https://openalex.org/keywords/hydrazine","display_name":"hydrazine","score":0.8949999809265137},{"id":"https://openalex.org/keywords/acid-cleavage","display_name":"acid cleavage","score":0.5170000195503235},{"id":"https://openalex.org/keywords/heterocyclic-amines","display_name":"heterocyclic amines","score":0.7300000190734863}],"concepts":[{"id":"https://openalex.org/C44280652","wikidata":"https://www.wikidata.org/wiki/Q104837","display_name":"Phase (matter)","level":2,"score":0.6421543955802917},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4980192184448242},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2032066285610199}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1021/cc049973b","doi":"https://doi.org/10.1021/cc049973b","is_oa":false,"landing_page_url":"https://doi.org/10.1021/cc049973b","pdf_url":null,"source":{"id":"https://openalex.org/S4210175341","display_name":"Journal of Combinatorial Chemistry","issn_l":"1520-4766","issn":["1520-4766","1520-4774"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Combinatorial Chemistry","raw_type":"journal-article"},{"id":"pmid:15360209","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15360209","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of combinatorial chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W1489681217","https://openalex.org/W1986170186","https://openalex.org/W1990691978","https://openalex.org/W1995346720","https://openalex.org/W2000196730","https://openalex.org/W2003370842","https://openalex.org/W2014406932","https://openalex.org/W2017332712","https://openalex.org/W2021767514","https://openalex.org/W2022355281","https://openalex.org/W2031415145","https://openalex.org/W2031698690","https://openalex.org/W2033267458","https://openalex.org/W2041719513","https://openalex.org/W2043410750","https://openalex.org/W2046411616","https://openalex.org/W2048496346","https://openalex.org/W2068740346","https://openalex.org/W2070903431","https://openalex.org/W2072719700","https://openalex.org/W2089571021","https://openalex.org/W2090863707","https://openalex.org/W2093761223","https://openalex.org/W2094954825","https://openalex.org/W2095189786","https://openalex.org/W2110478240","https://openalex.org/W2126905278","https://openalex.org/W2161387593","https://openalex.org/W2171580997","https://openalex.org/W2325290743","https://openalex.org/W2621561856","https://openalex.org/W2914210023","https://openalex.org/W2949678656","https://openalex.org/W2949680497","https://openalex.org/W2951172790","https://openalex.org/W2951234811","https://openalex.org/W2952068413"],"related_works":["https://openalex.org/W2045756372","https://openalex.org/W2471344932","https://openalex.org/W2005093324","https://openalex.org/W1968771767","https://openalex.org/W2061054685","https://openalex.org/W2030863551","https://openalex.org/W2068627999","https://openalex.org/W1981744862","https://openalex.org/W2070253023","https://openalex.org/W1971841916"],"abstract_inverted_index":{"An":[0],"efficient":[1],"and":[2,53,56,82],"advantageous":[3],"solid-phase":[4],"strategy":[5],"has":[6],"been":[7],"developed":[8],"to":[9,21,31],"synthesize":[10],"1,3,4-thiadiazolium-2-aminides.":[11],"The":[12,69],"title":[13],"compounds":[14],"were":[15,75],"prepared":[16],"in":[17,73,84],"parallel":[18],"fashion":[19],"according":[20],"the":[22,32,50,60,63],"following":[23],"compact":[24],"route:":[25],"(i)":[26],"anchoring":[27],"of":[28,38,59],"aromatic":[29],"aldehydes":[30,52],"solid":[33,64],"support;":[34],"(ii)":[35],"solution":[36],"preparation":[37],"1,4-disubstituted":[39,54],"thiosemicarbazides":[40],"from":[41,62],"hydrazines":[42],"plus":[43],"isothiocyanates;":[44],"(iii)":[45],"trimethylsilyl":[46],"chloride-promoted":[47],"cyclization":[48],"between":[49],"resin-bound":[51],"thiosemicarbazides;":[55],"(iv)":[57],"removal":[58],"products":[61,70],"support":[65],"by":[66],"acid":[67],"treatment.":[68],"(17":[71],"made":[72],"all)":[74],"cleaved":[76],"with":[77,90],"high":[78],"initial":[79],"purities":[80],"(90-98%)":[81],"obtained":[83],"generally":[85],"good":[86],"isolated":[87],"yields":[88],"(53-94%,":[89],"one":[91],"exception).":[92]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2016-06-24T00:00:00"}