{"id":"https://openalex.org/W2171362613","doi":null,"title":"Network meta-analysis on the comparative effectiveness and safety of transcatheter aortic valve implantation with CoreValve or Sapien devices versus surgical replacement.","display_name":"Network meta-analysis on the comparative effectiveness and safety of transcatheter aortic valve implantation with CoreValve or Sapien devices versus surgical replacement.","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2171362613","mag":"2171362613","pmid":"https://pubmed.ncbi.nlm.nih.gov/25436205","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4246842"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:3213191","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4246842","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4246842","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073353856","display_name":"Giuseppe Biondi\u2010Zoccai","orcid":"https://orcid.org/0000-0001-6103-8510","observed_orcids":["https://orcid.org/0000-0001-6103-8510"]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]},{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT","US"],"is_corresponding":false,"raw_author_name":"G Biondi-Zoccai","raw_affiliation_strings":["Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy ; VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy ; VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, USA","institution_ids":["https://openalex.org/I184840846","https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068987616","display_name":"Mariangela Peruzzi","orcid":"https://orcid.org/0000-0002-9036-8495","observed_orcids":["https://orcid.org/0000-0002-9036-8495","https://orcid.org/0009-0009-7268-5188"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M Peruzzi","raw_affiliation_strings":["Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049273996","display_name":"Antonio Abbate","orcid":"https://orcid.org/0000-0002-1930-785X","observed_orcids":["https://orcid.org/0000-0002-1930-785X"]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]},{"id":"https://openalex.org/I72019824","display_name":"Virginia Commonwealth University Medical Center","ror":"https://ror.org/057xmsr27","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I72019824"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A Abbate","raw_affiliation_strings":["VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, USA","institution_ids":["https://openalex.org/I184840846","https://openalex.org/I72019824"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015095883","display_name":"Zachary M. Gertz","orcid":"https://orcid.org/0000-0002-9613-5246","observed_orcids":["https://orcid.org/0000-0002-9613-5246"]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]},{"id":"https://openalex.org/I72019824","display_name":"Virginia Commonwealth University Medical Center","ror":"https://ror.org/057xmsr27","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I72019824"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Z M Gertz","raw_affiliation_strings":["VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, USA","institution_ids":["https://openalex.org/I184840846","https://openalex.org/I72019824"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018195873","display_name":"Umberto Benedetto","orcid":"https://orcid.org/0000-0002-7074-7949","observed_orcids":["https://orcid.org/0000-0002-7074-7949"]},"institutions":[{"id":"https://openalex.org/I2802782613","display_name":"Harefield Hospital","ror":"https://ror.org/04fwa4t58","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800036501","https://openalex.org/I2802782613"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"U Benedetto","raw_affiliation_strings":["Department of Cardiac Surgery, Harefield Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac Surgery, Harefield Hospital, London, UK","institution_ids":["https://openalex.org/I2802782613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058696249","display_name":"Euclide Tonelli","orcid":"https://orcid.org/0000-0001-6146-5694","observed_orcids":["https://orcid.org/0000-0001-6146-5694"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"E Tonelli","raw_affiliation_strings":["Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033242180","display_name":"Fabrizio D\u2019Ascenzo","orcid":"https://orcid.org/0000-0002-6646-9317","observed_orcids":["https://orcid.org/0000-0002-6646-9317"]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"F D'Ascenzo","raw_affiliation_strings":["Division of Cardiology, Department of Internal Medicine, University of Turin, Turin, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Internal Medicine, University of Turin, Turin, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101424844","display_name":"Arturo Giordano","orcid":"https://orcid.org/0000-0002-5467-8736","observed_orcids":["https://orcid.org/0000-0002-5467-8736"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Giordano","raw_affiliation_strings":["Unit\u00e0 Operativa di Interventistica Cardiovascolare, Presidio Ospedaliero Pineta Grande, Castel Volturno, and Unit\u00e0 Operativa di Emodinamica, Casa di Salute Santa Lucia, San Giuseppe Vesuviano, both in Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit\u00e0 Operativa di Interventistica Cardiovascolare, Presidio Ospedaliero Pineta Grande, Castel Volturno, and Unit\u00e0 Operativa di Emodinamica, Casa di Salute Santa Lucia, San Giuseppe Vesuviano, both in Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006222269","display_name":"Pierfrancesco Agostoni","orcid":"https://orcid.org/0000-0002-1505-9369","observed_orcids":["https://orcid.org/0000-0002-1505-9369"]},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"P Agostoni","raw_affiliation_strings":["Division of Cardiology, Utrecht University Medical Center, Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Utrecht University Medical Center, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082527578","display_name":"Giacomo Frati","orcid":"https://orcid.org/0000-0003-2703-3761","observed_orcids":["https://orcid.org/0000-0003-2703-3761"]},"institutions":[{"id":"https://openalex.org/I3018288129","display_name":"Istituto Neurologico Mediterraneo","ror":"https://ror.org/00cpb6264","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I3018288129","https://openalex.org/I4210153126"]},{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G Frati","raw_affiliation_strings":["Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy; Department of AngioCardioNeurology, IRCCS Neuromed, Pozzilli, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy; Department of AngioCardioNeurology, IRCCS Neuromed, Pozzilli, Italy","institution_ids":["https://openalex.org/I3018288129","https://openalex.org/I861853513"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.3093,"has_fulltext":false,"cited_by_count":40,"citation_normalized_percentile":{"value":0.93124792,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"6","issue":"4","first_page":"232","last_page":"43"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10618","display_name":"Aortic Disease and Treatment Approaches","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11551","display_name":"Infective Endocarditis Diagnosis and Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transcatheter-aortic-valve-replacement","display_name":"transcatheter aortic valve implantation","score":0.9760000109672546},{"id":"https://openalex.org/keywords/surgical-aortic-valve-replacement","display_name":"surgical aortic valve replacement","score":0.9020000100135803},{"id":"https://openalex.org/keywords/aortic-stenosis","display_name":"aortic stenosis","score":0.9860000014305115},{"id":"https://openalex.org/keywords/corevalve","display_name":"CoreValve","score":0.9850000143051147},{"id":"https://openalex.org/keywords/sapien-valve","display_name":"Sapien valve","score":0.9419999718666077},{"id":"https://openalex.org/keywords/major-bleeding","display_name":"major bleeding","score":0.6669999957084656},{"id":"https://openalex.org/keywords/acute-kidney-injury","display_name":"acute kidney injury","score":0.8970000147819519},{"id":"https://openalex.org/keywords/stroke","display_name":"stroke","score":0.6809999942779541},{"id":"https://openalex.org/keywords/pacemaker-implantation","display_name":"pacemaker implantation","score":0.9860000014305115},{"id":"https://openalex.org/keywords/aortic-regurgitation","display_name":"aortic regurgitation","score":0.9259999990463257},{"id":"https://openalex.org/keywords/all-cause-mortality","display_name":"all-cause mortality","score":0.8479999899864197},{"id":"https://openalex.org/keywords/comparative-effectiveness","display_name":"comparative effectiveness","score":0.4950000047683716},{"id":"https://openalex.org/keywords/transapical-approach","display_name":"transapical approach","score":0.8330000042915344},{"id":"https://openalex.org/keywords/femoral-access","display_name":"transfemoral access","score":0.9869999885559082},{"id":"https://openalex.org/keywords/high-risk-patients","display_name":"high-risk patients","score":0.6010000109672546},{"id":"https://openalex.org/keywords/minimally-invasive-surgery","display_name":"minimally invasive surgery","score":0.5389999747276306}],"concepts":[{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.9132697582244873},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7759848237037659},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6127711534500122},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.4558722674846649},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4539002776145935},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.44338977336883545},{"id":"https://openalex.org/C2781414266","wikidata":"https://www.wikidata.org/wiki/Q531019","display_name":"Aortic valve stenosis","level":3,"score":0.4157552421092987},{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.38565143942832947}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:oai:europepmc.org:3213191","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4246842","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4246842","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4246842","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Heart Lung Vessel","raw_type":"Text"},{"id":"pmid:25436205","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25436205","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Heart, lung and vessels","raw_type":"Journal Article"},{"id":"pmh:oai:iris.uniroma1.it:11573/656051","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11573/656051","pdf_url":null,"source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2171362613","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25436205","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:3213191","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4246842","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W48844573","https://openalex.org/W154292533","https://openalex.org/W1598602811","https://openalex.org/W1932832777","https://openalex.org/W1968963971","https://openalex.org/W1978723154","https://openalex.org/W1979248228","https://openalex.org/W1991161977","https://openalex.org/W1999023967","https://openalex.org/W2006541164","https://openalex.org/W2018052575","https://openalex.org/W2021108393","https://openalex.org/W2022851384","https://openalex.org/W2028412273","https://openalex.org/W2036263563","https://openalex.org/W2068694980","https://openalex.org/W2072681305","https://openalex.org/W2090857253","https://openalex.org/W2107912271","https://openalex.org/W2132585880","https://openalex.org/W2134833483","https://openalex.org/W2144981148","https://openalex.org/W2149609916","https://openalex.org/W2154923036","https://openalex.org/W2165258820","https://openalex.org/W2165918244","https://openalex.org/W2323380817","https://openalex.org/W2331384579","https://openalex.org/W2410217433","https://openalex.org/W2605849388","https://openalex.org/W3022903699","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2941677670","https://openalex.org/W2474606013","https://openalex.org/W7115009882","https://openalex.org/W2807744705","https://openalex.org/W2165258820","https://openalex.org/W4416032508","https://openalex.org/W4238660727","https://openalex.org/W2527506257","https://openalex.org/W4247654442","https://openalex.org/W4310506323"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Surgical":[1],"replacement":[2,44,227],"for":[3],"aortic":[4,42,164,225,253],"stenosis":[5],"is":[6,27,228],"fraught":[7],"with":[8,60,68,103,181,184,204],"complications":[9],"in":[10,235,251],"high-risk":[11],"patients.":[12],"Transcatheter":[13],"techniques":[14],"may":[15],"offer":[16],"a":[17,31,74],"minimally":[18],"invasive":[19],"solution,":[20],"but":[21,148,230],"their":[22],"comparative":[23],"effectiveness":[24,240],"and":[25,82,131,160,239,246],"safety":[26,238],"uncertain.":[28],"We":[29],"performed":[30],"network":[32,62],"meta-analysis":[33],"on":[34,40],"this":[35],"topic.":[36],"METHODS:":[37],"Randomized":[38],"trials":[39,67],"transcatheter":[41,92,222,252],"valve":[43,226,254],"vs":[45,111,119,126,137,143,156,168,174,208,214],"surgery":[46,90,100,209],"were":[47,58,71,178],"searched.":[48],"The":[49],"primary":[50],"outcome":[51],"was":[52,85,101,201],"all":[53],"cause":[54],"death.":[55],"Risk":[56],"estimates":[57],"obtained":[59],"Bayesian":[61],"meta-analytic":[63],"methods.":[64],"RESULTS:":[65],"Four":[66],"1,805":[69],"patients":[70],"included.":[72],"After":[73],"median":[75],"of":[76,80,95,106,151],"8":[77],"months,":[78],"risk":[79],"death":[81],"myocardial":[83],"infarction":[84],"not":[86],"different":[87],"when":[88],"comparing":[89],"versus":[91],"procedures,":[93],"irrespective":[94],"device":[96],"or":[97,162,191,223],"access.":[98],"Conversely,":[99],"associated":[102],"higher":[104],"rates":[105,150],"major":[107],"bleeding":[108],"(odds":[109,135,154,166,187,194,206],"ratio":[110,118,125,136,142,155,167,173,188,195,207,213],"CoreValve=3.03":[112],"[95%":[113],"credible":[114],"interval:":[115],"2.23-4.17];":[116],"odds":[117,124,141,172,212],"transfemoral":[120,185,215],"Sapien":[121,128,145,186,193,216],"=1.82":[122],"[1.21-2.70];":[123],"transapical":[127,144,192],"=2.08":[129,139],"[1.20-3.70]),":[130],"acute":[132],"kidney":[133],"injury":[134],"CoreValve":[138,157,169,182,205],"[1.33-3.32];":[140],"=2.78":[146],"[2.21-99.80]),":[147],"lower":[149],"pacemaker":[152,199],"implantation":[153,200],"=0.41":[158],"[0.28-0.59]),":[159],"moderate":[161],"severe":[163],"regurgitation":[165],"=0.06":[170],"[0.02-0.27];":[171],"Sapien=0.17":[175],"[0.02-0.76]).":[176],"Strokes":[177],"less":[179],"frequent":[180],"than":[183],"=0.32":[189],"[0.13-0.73])":[190],"=0.33":[196],"[0.10-0.93]),":[197],"whereas":[198],"more":[202],"common":[203],"=2.46":[210],"[1.69-3.61];":[211],"=2.22":[217],"[1.27-3.85]).":[218],"CONCLUSIONS:":[219],"Survival":[220],"after":[221],"surgical":[224],"similar,":[229],"there":[231],"might":[232],"be":[233],"differences":[234],"the":[236,243,247],"individual":[237,248],"profile":[241],"between":[242],"treatment":[244],"strategies":[245],"devices":[249],"used":[250],"implantation.":[255]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":6}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}