{"id":"https://openalex.org/W2171233859","doi":"https://doi.org/10.3109/01485018508988288","title":"A New Instant Cryoprotectant for Human Sperm","display_name":"A New Instant Cryoprotectant for Human Sperm","publication_year":1985,"publication_date":"1985-01-01","ids":{"openalex":"https://openalex.org/W2171233859","doi":"https://doi.org/10.3109/01485018508988288","mag":"2171233859","pmid":"https://pubmed.ncbi.nlm.nih.gov/3851655"},"language":"en","primary_location":{"id":"doi:10.3109/01485018508988288","doi":"https://doi.org/10.3109/01485018508988288","is_oa":false,"landing_page_url":"https://doi.org/10.3109/01485018508988288","pdf_url":null,"source":{"id":"https://openalex.org/S206725715","display_name":"Archives of Andrology","issn_l":"0148-5016","issn":["0148-5016","1521-0375"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Andrology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067818736","display_name":"Rudolf H. Kaden","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Kaden","raw_affiliation_strings":["Andrological Work Group for Cryosperm Research, University Medical Centrem, Berlin-Steglitz, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Andrological Work Group for Cryosperm Research, University Medical Centrem, Berlin-Steglitz, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000703089","display_name":"F. Klippel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114188","display_name":"Allgemeines Krankenhaus Celle","ror":"https://ror.org/0205x2f04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210114188"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"F. F. Klippel","raw_affiliation_strings":["Department of Urology, Municipal Hospital, Celle, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Municipal Hospital, Celle, Germany","institution_ids":["https://openalex.org/I4210114188"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112543430","display_name":"Th. Katzorke","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Th. Katzorke","raw_affiliation_strings":["Andrological Work Group for Cryosperm Research, University Medical Centrem, Berlin-Steglitz, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Andrological Work Group for Cryosperm Research, University Medical Centrem, Berlin-Steglitz, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076809479","display_name":"Dirk Propping","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. Propping","raw_affiliation_strings":["Fertility Institute, Essen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fertility Institute, Essen, Germany","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042622101","display_name":"D. Schone","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210135061","display_name":"SteriPharm (Germany)","ror":"https://ror.org/03vhzfd61","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210135061"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"D. Schone","raw_affiliation_strings":["SteriPharm Pharmaceutical Products, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SteriPharm Pharmaceutical Products, Berlin, Germany","institution_ids":["https://openalex.org/I4210135061"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5448,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.57267247,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"14","issue":"2-3","first_page":"133","last_page":"137"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11505","display_name":"Reproductive biology and impacts on aquatic species","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-sperm-cryopreservation","display_name":"human sperm cryopreservation","score":0.9380000233650208},{"id":"https://openalex.org/keywords/sperm-cryopreservation","display_name":"sperm cryopreservation","score":0.722000002861023},{"id":"https://openalex.org/keywords/human-serum-albumin","display_name":"human serum albumin","score":0.9649999737739563},{"id":"https://openalex.org/keywords/kallikrein","display_name":"kallikrein","score":0.9990000128746033},{"id":"https://openalex.org/keywords/sperm-retrieval-rate","display_name":"sperm retrieval rate","score":0.8569999933242798}],"concepts":[{"id":"https://openalex.org/C68528507","wikidata":"https://www.wikidata.org/wiki/Q692267","display_name":"Cryoprotectant","level":4,"score":0.9800617694854736},{"id":"https://openalex.org/C179933525","wikidata":"https://www.wikidata.org/wiki/Q1144664","display_name":"Cryopreservation","level":3,"score":0.7566856741905212},{"id":"https://openalex.org/C2781321622","wikidata":"https://www.wikidata.org/wiki/Q181409","display_name":"Yolk","level":2,"score":0.6841504573822021},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.5905580520629883},{"id":"https://openalex.org/C2781087480","wikidata":"https://www.wikidata.org/wiki/Q17145","display_name":"Sperm","level":2,"score":0.5758684873580933},{"id":"https://openalex.org/C2778093475","wikidata":"https://www.wikidata.org/wiki/Q9715","display_name":"Semen","level":2,"score":0.5420814752578735},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49195072054862976},{"id":"https://openalex.org/C2778022349","wikidata":"https://www.wikidata.org/wiki/Q1072553","display_name":"Vitrification","level":2,"score":0.43914806842803955},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.27112239599227905},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.16584059596061707},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11159932613372803},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.07888135313987732}],"mesh":[{"descriptor_ui":"D002951","descriptor_name":"Citrates","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003451","descriptor_name":"Cryoprotective Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003470","descriptor_name":"Culture Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004530","descriptor_name":"Egg Yolk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007610","descriptor_name":"Kallikreins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012662","descriptor_name":"Semen Preservation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012709","descriptor_name":"Serum Albumin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013081","descriptor_name":"Sperm Motility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013094","descriptor_name":"Spermatozoa","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019343","descriptor_name":"Citric Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3109/01485018508988288","doi":"https://doi.org/10.3109/01485018508988288","is_oa":false,"landing_page_url":"https://doi.org/10.3109/01485018508988288","pdf_url":null,"source":{"id":"https://openalex.org/S206725715","display_name":"Archives of Andrology","issn_l":"0148-5016","issn":["0148-5016","1521-0375"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Andrology","raw_type":"journal-article"},{"id":"pmid:3851655","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3851655","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of andrology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W88701652","https://openalex.org/W174198420","https://openalex.org/W1410878127","https://openalex.org/W2086379024","https://openalex.org/W2152532011","https://openalex.org/W2498634963","https://openalex.org/W2616365342","https://openalex.org/W4238202475","https://openalex.org/W4249840665"],"related_works":["https://openalex.org/W2413605312","https://openalex.org/W2152532011","https://openalex.org/W2401809108","https://openalex.org/W652053521","https://openalex.org/W2356011012","https://openalex.org/W3200306272","https://openalex.org/W2392380297","https://openalex.org/W3118934810","https://openalex.org/W2746969086","https://openalex.org/W2046196842"],"abstract_inverted_index":{"A":[0,24],"new":[1,58],"instant":[2,39,59],"cryoprotectant,":[3],"mainly":[4],"containing":[5],"culture":[6],"medium,":[7],"human":[8,89],"serum":[9],"albumin,":[10],"and":[11,13,70],"kallikrein,":[12],"its":[14,73],"laboratory":[15],"handling":[16],"in":[17,64,72,85],"the":[18,57,65,86],"cryoprotection":[19],"of":[20,56,67,88],"semen":[21],"are":[22],"described.":[23],"comparative":[25],"study":[26],"distributed":[27],"to":[28,83],"three":[29],"cryobiological":[30],"centers":[31],"using":[32],"either":[33],"egg":[34,68],"yolk":[35,69],"citrate":[36],"medium":[37],"or":[38,48],"cryoprotectant":[40,60],"showed":[41],"that":[42],"neither":[43],"had":[44],"a":[45],"significantly":[46],"better":[47],"worse":[49],"mean":[50],"percentage":[51],"recovery":[52],"rate.":[53],"The":[54],"advantage":[55],"presented":[61],"consists":[62],"clinically":[63],"absence":[66],"technically":[71],"easy":[74],"handling.":[75],"Therefore,":[76],"ICP":[77],"is":[78],"judged":[79],"as":[80],"an":[81],"alternative":[82],"ECM":[84],"cryopreservation":[87],"sperm.":[90]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}