{"id":"https://openalex.org/W2171069167","doi":"https://doi.org/10.1016/s0040-4039(00)93510-x","title":"A simple synthesis of \u03a9[(E)CHCH]gly dipeptide isosteres via reductive elimination of \u03b3-oxygenated \u03b1,\u03b2-enoates with alkenylcopper reagents","display_name":"A simple synthesis of \u03a9[(E)CHCH]gly dipeptide isosteres via reductive elimination of \u03b3-oxygenated \u03b1,\u03b2-enoates with alkenylcopper reagents","publication_year":1991,"publication_date":"1991-09-01","ids":{"openalex":"https://openalex.org/W2171069167","doi":"https://doi.org/10.1016/s0040-4039(00)93510-x","mag":"2171069167"},"language":"en","primary_location":{"id":"doi:10.1016/s0040-4039(00)93510-x","doi":"https://doi.org/10.1016/s0040-4039(00)93510-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0040-4039(00)93510-x","pdf_url":null,"source":{"id":"https://openalex.org/S133942674","display_name":"Tetrahedron Letters","issn_l":"0040-4039","issn":["0040-4039","1873-3581"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tetrahedron Letters","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2171069167"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010841219","display_name":"Nobutaka Fujiia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobutaka Fujiia","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Kyoto University, Kyoto 606, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Kyoto University, Kyoto 606, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089615815","display_name":"Hiromu Habashita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiromu Habashita","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Kyoto University, Kyoto 606, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Kyoto University, Kyoto 606, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111971497","display_name":"Noriko Shigemori","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Noriko Shigemori","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Kyoto University, Kyoto 606, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Kyoto University, Kyoto 606, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111866358","display_name":"Akira Otaka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akira Otaka","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Kyoto University, Kyoto 606, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Kyoto University, Kyoto 606, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075743315","display_name":"Toshiro Ibuka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshiro Ibuka","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Kyoto University, Kyoto 606, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Kyoto University, Kyoto 606, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023730666","display_name":"Miwa Tanaka","orcid":"https://orcid.org/0000-0003-4934-3787","observed_orcids":["https://orcid.org/0000-0003-4934-3787"]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Miwa Tanaka","raw_affiliation_strings":["Department of Chemistry, Faculty of Science, Tohoku University, Sendai 980, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Science, Tohoku University, Sendai 980, Japan","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084597243","display_name":"Yoshinori Yamamoto","orcid":"https://orcid.org/0000-0001-9411-783X","observed_orcids":["https://orcid.org/0000-0001-9411-783X"]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshinori Yamamoto","raw_affiliation_strings":["Department of Chemistry, Faculty of Science, Tohoku University, Sendai 980, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Science, Tohoku University, Sendai 980, Japan","institution_ids":["https://openalex.org/I201537933"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3610,"currency":"USD","value_usd":3610},"apc_paid":null,"fwci":2.4286,"has_fulltext":false,"cited_by_count":26,"citation_normalized_percentile":{"value":0.88881787,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"32","issue":"37","first_page":"4969","last_page":"4972"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.8949999809265137,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.8949999809265137,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13649","display_name":"Advanced Synthetic Organic Chemistry","score":0.06650000065565109,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13859","display_name":"Organic Chemistry Synthesis Methods","score":0.01140000019222498,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dipeptide-isosteres","display_name":"dipeptide isosteres","score":0.8939999938011169},{"id":"https://openalex.org/keywords/reductive-elimination","display_name":"reductive elimination","score":0.9769999980926514},{"id":"https://openalex.org/keywords/peptide-synthesis","display_name":"peptide synthesis","score":0.3959999978542328},{"id":"https://openalex.org/keywords/protected-amino-acids","display_name":"protected amino acids","score":0.4020000100135803}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9788844585418701},{"id":"https://openalex.org/C2779138802","wikidata":"https://www.wikidata.org/wiki/Q418602","display_name":"Dipeptide","level":3,"score":0.9285308122634888},{"id":"https://openalex.org/C40875361","wikidata":"https://www.wikidata.org/wiki/Q2356542","display_name":"Reagent","level":2,"score":0.6931332945823669},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.4809531271457672},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.45470625162124634},{"id":"https://openalex.org/C181647583","wikidata":"https://www.wikidata.org/wiki/Q903429","display_name":"Stereoselectivity","level":3,"score":0.4339306354522705},{"id":"https://openalex.org/C2780586882","wikidata":"https://www.wikidata.org/wiki/Q7520643","display_name":"Simple (philosophy)","level":2,"score":0.419364869594574},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.3155551254749298},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.16978847980499268},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.11567485332489014},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07454290986061096},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0040-4039(00)93510-x","doi":"https://doi.org/10.1016/s0040-4039(00)93510-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0040-4039(00)93510-x","pdf_url":null,"source":{"id":"https://openalex.org/S133942674","display_name":"Tetrahedron Letters","issn_l":"0040-4039","issn":["0040-4039","1873-3581"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tetrahedron Letters","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320310145","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95"},{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1602688875","https://openalex.org/W1606719843","https://openalex.org/W1979679114","https://openalex.org/W1982801021","https://openalex.org/W1985078307","https://openalex.org/W1993228812","https://openalex.org/W1999984996","https://openalex.org/W2010783155","https://openalex.org/W2011368232","https://openalex.org/W2014098216","https://openalex.org/W2037057963","https://openalex.org/W2046894860","https://openalex.org/W2060492314","https://openalex.org/W2074867994","https://openalex.org/W2091291363","https://openalex.org/W2091974662","https://openalex.org/W2092657563","https://openalex.org/W2097090664","https://openalex.org/W2123604677","https://openalex.org/W2156030621","https://openalex.org/W2164876110","https://openalex.org/W4242341673"],"related_works":["https://openalex.org/W3048039214","https://openalex.org/W2009000697","https://openalex.org/W2099927244","https://openalex.org/W192004178","https://openalex.org/W2097090664","https://openalex.org/W2055408091","https://openalex.org/W1996906822","https://openalex.org/W2498856290","https://openalex.org/W2160096391","https://openalex.org/W2007968437"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}