{"id":"https://openalex.org/W2170772222","doi":null,"title":"THE IMPORTANCE OF DETERMINING THE PRESENCE AND DEGREE OF INSULIN RESISTANCE IN THE GENERAL POPULATION AND IN SOME CLINICAL STATES","display_name":"THE IMPORTANCE OF DETERMINING THE PRESENCE AND DEGREE OF INSULIN RESISTANCE IN THE GENERAL POPULATION AND IN SOME CLINICAL STATES","publication_year":2005,"publication_date":"2005-01-01","ids":{"openalex":"https://openalex.org/W2170772222","mag":"2170772222"},"language":"en","primary_location":{"id":"mag:2170772222","doi":null,"is_oa":false,"landing_page_url":"http://www.idb.hr/diabetologia/05no1-1.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068293791","display_name":"Diana Mua\u00e8evi\u00e6-Katanec","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Diana Mua\u00e8evi\u00e6-Katanec","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5068293791"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.007000000216066837,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":1.0},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9070000052452087},{"id":"https://openalex.org/keywords/abdominal-obesity","display_name":"abdominal obesity","score":0.8370000123977661},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.890999972820282},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.8479999899864197},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.9980000257492065},{"id":"https://openalex.org/keywords/polycystic-ovary-syndrome","display_name":"polycystic ovary syndrome","score":1.0},{"id":"https://openalex.org/keywords/gestational-diabetes-mellitus","display_name":"gestational diabetes mellitus","score":0.7269999980926514},{"id":"https://openalex.org/keywords/impaired-glucose-tolerance","display_name":"impaired glucose tolerance","score":0.9670000076293945},{"id":"https://openalex.org/keywords/homa","display_name":"HOMA","score":0.8220000267028809},{"id":"https://openalex.org/keywords/frequently-sampled-intravenous-glucose-tolerance-test","display_name":"frequently sampled intravenous glucose tolerance test","score":0.8330000042915344},{"id":"https://openalex.org/keywords/beta-cell-function","display_name":"beta-cell function","score":0.7089999914169312}],"concepts":[{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.8955799341201782},{"id":"https://openalex.org/C2778096610","wikidata":"https://www.wikidata.org/wiki/Q1476525","display_name":"Dyslipidemia","level":3,"score":0.729256808757782},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7008473873138428},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.673208475112915},{"id":"https://openalex.org/C3018442814","wikidata":"https://www.wikidata.org/wiki/Q500816","display_name":"Polycystic ovary","level":4,"score":0.6503961086273193},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6297937035560608},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.614019513130188},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.580169677734375},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.575157880783081},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.4888867437839508},{"id":"https://openalex.org/C2777693730","wikidata":"https://www.wikidata.org/wiki/Q1140549","display_name":"Abdominal obesity","level":4,"score":0.4625083804130554},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.45331645011901855},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.42225685715675354},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.3660586476325989},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2170772222","doi":null,"is_oa":false,"landing_page_url":"http://www.idb.hr/diabetologia/05no1-1.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1554325522","https://openalex.org/W1562849051","https://openalex.org/W1971998406","https://openalex.org/W1973706205","https://openalex.org/W1987560885","https://openalex.org/W1993757598","https://openalex.org/W2014557527","https://openalex.org/W2029485107","https://openalex.org/W2033667814","https://openalex.org/W2034751031","https://openalex.org/W2041196365","https://openalex.org/W2046582809","https://openalex.org/W2072474124","https://openalex.org/W2077411869","https://openalex.org/W2086082646","https://openalex.org/W2099876016","https://openalex.org/W2105912552","https://openalex.org/W2108280526","https://openalex.org/W2115936360","https://openalex.org/W2116626049","https://openalex.org/W2123675377","https://openalex.org/W2124620553","https://openalex.org/W2124647455","https://openalex.org/W2132485307","https://openalex.org/W2143146488","https://openalex.org/W2155059543","https://openalex.org/W2160234571","https://openalex.org/W2163261947","https://openalex.org/W2165126187","https://openalex.org/W2165785647","https://openalex.org/W2283253829","https://openalex.org/W2407503803"],"related_works":["https://openalex.org/W4231317203","https://openalex.org/W2134922435","https://openalex.org/W2523572522","https://openalex.org/W2101736211","https://openalex.org/W4405014137","https://openalex.org/W2089770443","https://openalex.org/W1967937969","https://openalex.org/W2201765620","https://openalex.org/W4401396706","https://openalex.org/W2167403702"],"abstract_inverted_index":{"Insulin":[0,22,60,89],"resistance":[1,23,34,50,61,90,180,232],"is":[2,17,62,213],"the":[3,39,52,74,129,174,219,222,228],"inability":[4],"of":[5,29,41,48,73,100,110,132,148,178,194,221,224,230],"insulin":[6,30,33,49,159,165,168,179,231,239],"to":[7,38,163],"produce":[8],"its":[9],"common":[10],"biological":[11],"effect":[12],"at":[13],"a":[14,56,97,108,215],"concentration":[15],"which":[16],"efficacious":[18],"in":[19,26,51,94,103,123,134,139],"healthy":[20],"individuals.":[21],"can":[24],"develop":[25],"all":[27],"aspects":[28],"action.":[31],"As":[32],"frequently":[35,185,209],"occurs":[36],"prior":[37],"diagnosis":[40],"different":[42],"clinical":[43],"states,":[44],"identifying":[45],"and":[46,70,85,126,167,176,200,227,238],"treatment":[47],"general":[53],"population":[54],"has":[55],"certain":[57],"preventive":[58],"significance.":[59],"etiopathogenetically":[63],"associated":[64],"with":[65,96,107,128,141,196],"type":[66,131],"2":[67],"diabetes":[68,101,112],"mellitus":[69,102],"obesity":[71,133],"(mainly":[72],"central":[75],"type),":[76],"arterial":[77,117],"hypertension,":[78,118],"cardiovascular":[79],"diseases,":[80],"dyslipidemia,":[81,119],"polycystic":[82,142],"ovary":[83,143],"syndrome,":[84],"some":[86],"other":[87],"disorders.":[88],"should":[91],"be":[92],"suspected":[93],"patients":[95,106],"family":[98],"history":[99,109],"closest":[104],"relatives,":[105],"gestational":[111],"or":[113],"impaired":[114],"glucose":[115,188,195,236],"tolerance,":[116],"elevated":[120],"liver":[121],"enzymes,":[122],"obese":[124],"persons":[125],"those":[127,140],"abdominal":[130],"particular":[135],"as":[136,138,182],"well":[137],"syndrome.":[144],"A":[145],"separate":[146],"group":[147],"clinically":[149],"very":[150],"interesting":[151],"diseases":[152],"are":[153,205],"inherited":[154],"syndromes":[155],"characterized":[156],"by":[157],"extreme":[158],"resistance,":[160],"contributing":[161],"significantly":[162],"reduced":[164],"action":[166],"resistance.":[169],"Several":[170],"methods":[171],"for":[172,218],"determining":[173],"presence":[175],"degree":[177,229],"such":[181],"clamp":[183],"technique,":[184],"sampled":[186],"intravenous":[187],"tolerance":[189],"test":[190],"(FSIVGTT),":[191],"continuous":[192],"infusion":[193],"model":[197,202],"assessment":[198,203],"(CIGMA),":[199],"homeostasis":[201],"(HOMA)":[204],"described.":[206],"The":[207],"most":[208],"used":[210],"method":[211,217],"today":[212],"HOMA,":[214],"simple":[216],"evaluation":[220],"function":[223],"beta":[225],"cells":[226],"from":[233],"basal":[234],"(fasting)":[235],"values":[237],"concentrations.":[240]},"counts_by_year":[],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2016-06-24T00:00:00"}