{"id":"https://openalex.org/W2170695101","doi":"https://doi.org/10.1016/s0387-7604(01)00367-9","title":"Development of language in Rett syndrome","display_name":"Development of language in Rett syndrome","publication_year":2001,"publication_date":"2001-12-01","ids":{"openalex":"https://openalex.org/W2170695101","doi":"https://doi.org/10.1016/s0387-7604(01)00367-9","mag":"2170695101","pmid":"https://pubmed.ncbi.nlm.nih.gov/11738880"},"language":"en","primary_location":{"id":"doi:10.1016/s0387-7604(01)00367-9","doi":"https://doi.org/10.1016/s0387-7604(01)00367-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0387-7604(01)00367-9","pdf_url":null,"source":{"id":"https://openalex.org/S122866201","display_name":"Brain and Development","issn_l":"0387-7604","issn":["0387-7604","1872-7131"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","erih-plus","jufo-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain and Development","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041545804","display_name":"June Uchino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210167288","display_name":"Segawa Neurological Clinic for Children","ror":"https://ror.org/05r99t981","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210167288"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"June Uchino","raw_affiliation_strings":["Segawa Neurological Clinic for Children, 2-8 Surugadai, Kanda Chiyodaku, 101-0062, Tokyo, Japan","Segawa Neurological Clinic for Children, 2-8 Surugadai, Kanda Chiyodaku, Tokyo 101-0062, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Segawa Neurological Clinic for Children, 2-8 Surugadai, Kanda Chiyodaku, 101-0062, Tokyo, Japan","institution_ids":["https://openalex.org/I4210167288"]},{"raw_affiliation_string":"Segawa Neurological Clinic for Children, 2-8 Surugadai, Kanda Chiyodaku, Tokyo 101-0062, Japan","institution_ids":["https://openalex.org/I4210167288"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079904432","display_name":"Michiyo Suzuki","orcid":"https://orcid.org/0000-0002-9730-8532","observed_orcids":["https://orcid.org/0000-0002-9730-8532"]},"institutions":[{"id":"https://openalex.org/I4210167288","display_name":"Segawa Neurological Clinic for Children","ror":"https://ror.org/05r99t981","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210167288"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Michiyo Suzuki","raw_affiliation_strings":["Segawa Neurological Clinic for Children, 2-8 Surugadai, Kanda Chiyodaku, Tokyo 101-0062, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Segawa Neurological Clinic for Children, 2-8 Surugadai, Kanda Chiyodaku, Tokyo 101-0062, Japan","institution_ids":["https://openalex.org/I4210167288"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091345777","display_name":"Kyoko Hoshino","orcid":"https://orcid.org/0000-0001-6659-7485","observed_orcids":["https://orcid.org/0000-0001-6659-7485"]},"institutions":[{"id":"https://openalex.org/I4210167288","display_name":"Segawa Neurological Clinic for Children","ror":"https://ror.org/05r99t981","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210167288"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kyoko Hoshino","raw_affiliation_strings":["Segawa Neurological Clinic for Children, 2-8 Surugadai, Kanda Chiyodaku, Tokyo 101-0062, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Segawa Neurological Clinic for Children, 2-8 Surugadai, Kanda Chiyodaku, Tokyo 101-0062, Japan","institution_ids":["https://openalex.org/I4210167288"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104706426","display_name":"Yoshiko Nomura","orcid":"https://orcid.org/0000-0001-6021-0542","observed_orcids":["https://orcid.org/0000-0001-6021-0542"]},"institutions":[{"id":"https://openalex.org/I4210167288","display_name":"Segawa Neurological Clinic for Children","ror":"https://ror.org/05r99t981","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210167288"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshiko Nomura","raw_affiliation_strings":["Segawa Neurological Clinic for Children, 2-8 Surugadai, Kanda Chiyodaku, Tokyo 101-0062, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Segawa Neurological Clinic for Children, 2-8 Surugadai, Kanda Chiyodaku, Tokyo 101-0062, Japan","institution_ids":["https://openalex.org/I4210167288"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109523362","display_name":"Masaya Segawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210167288","display_name":"Segawa Neurological Clinic for Children","ror":"https://ror.org/05r99t981","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210167288"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaya Segawa","raw_affiliation_strings":["Segawa Neurological Clinic for Children, 2-8 Surugadai, Kanda Chiyodaku, Tokyo 101-0062, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Segawa Neurological Clinic for Children, 2-8 Surugadai, Kanda Chiyodaku, Tokyo 101-0062, Japan","institution_ids":["https://openalex.org/I4210167288"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5041545804"],"corresponding_institution_ids":["https://openalex.org/I4210167288"],"apc_list":{"value":2810,"currency":"USD","value_usd":2810},"apc_paid":null,"fwci":0.92,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.70906216,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"23","issue":null,"first_page":"S233","last_page":"S235"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11772","display_name":"Genetics and Neurodevelopmental Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11772","display_name":"Genetics and Neurodevelopmental Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10730","display_name":"Language Development and Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3204","display_name":"Developmental and Educational Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10106","display_name":"Autism Spectrum Disorder Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rett-syndrome","display_name":"Rett syndrome","score":1.0},{"id":"https://openalex.org/keywords/language-development","display_name":"language development","score":0.9390000104904175},{"id":"https://openalex.org/keywords/speech-development","display_name":"speech development","score":0.8320000171661377},{"id":"https://openalex.org/keywords/mecp2-mutations","display_name":"MECP2 mutations","score":0.7820000052452087},{"id":"https://openalex.org/keywords/vocabulary","display_name":"vocabulary","score":0.5960000157356262},{"id":"https://openalex.org/keywords/loss-of-speech","display_name":"speech loss","score":0.6890000104904175},{"id":"https://openalex.org/keywords/genotype-phenotype-correlation","display_name":"genotype-phenotype correlation","score":0.7080000042915344},{"id":"https://openalex.org/keywords/mutation-location","display_name":"mutation location","score":0.5049999952316284},{"id":"https://openalex.org/keywords/neural-systems","display_name":"neural systems","score":0.33799999952316284},{"id":"https://openalex.org/keywords/developmental-delay","display_name":"developmental delay","score":0.6100000143051147}],"concepts":[{"id":"https://openalex.org/C2778863441","wikidata":"https://www.wikidata.org/wiki/Q18028997","display_name":"MECP2","level":4,"score":0.8091182708740234},{"id":"https://openalex.org/C2777543196","wikidata":"https://www.wikidata.org/wiki/Q917357","display_name":"Rett syndrome","level":3,"score":0.7918342351913452},{"id":"https://openalex.org/C2777530160","wikidata":"https://www.wikidata.org/wiki/Q41796","display_name":"Sentence","level":2,"score":0.5285446047782898},{"id":"https://openalex.org/C90805587","wikidata":"https://www.wikidata.org/wiki/Q10944557","display_name":"Word (group theory)","level":2,"score":0.4779260754585266},{"id":"https://openalex.org/C2778073708","wikidata":"https://www.wikidata.org/wiki/Q2330667","display_name":"Language development","level":2,"score":0.4686813950538635},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4336183965206146},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4172726273536682},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.3894941806793213},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3868301808834076},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.2662050724029541},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.23936811089515686},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.23627042770385742},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22268611192703247},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.19877037405967712},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.17305660247802734},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002868","descriptor_name":"Chromosomal Proteins, Non-Histone","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004252","descriptor_name":"DNA Mutational Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007805","descriptor_name":"Language Development Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D007805","descriptor_name":"Language Development Disorders","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007805","descriptor_name":"Language Development Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013060","descriptor_name":"Speech","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015518","descriptor_name":"Rett Syndrome","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D015518","descriptor_name":"Rett Syndrome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015518","descriptor_name":"Rett Syndrome","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D051783","descriptor_name":"Methyl-CpG-Binding Protein 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0387-7604(01)00367-9","doi":"https://doi.org/10.1016/s0387-7604(01)00367-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0387-7604(01)00367-9","pdf_url":null,"source":{"id":"https://openalex.org/S122866201","display_name":"Brain and Development","issn_l":"0387-7604","issn":["0387-7604","1872-7131"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","erih-plus","jufo-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain and Development","raw_type":"journal-article"},{"id":"pmid:11738880","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11738880","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain & development","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W38110762","https://openalex.org/W1527640078","https://openalex.org/W1987642692","https://openalex.org/W2057427707","https://openalex.org/W2063840478","https://openalex.org/W2084828679"],"related_works":["https://openalex.org/W2132183715","https://openalex.org/W2408658061","https://openalex.org/W2098810164","https://openalex.org/W1866697318","https://openalex.org/W2090687033","https://openalex.org/W2014590941","https://openalex.org/W4403780421","https://openalex.org/W2004851675","https://openalex.org/W2033670108","https://openalex.org/W7143680581"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}