{"id":"https://openalex.org/W2170654271","doi":"https://doi.org/10.1007/s00411-009-0231-2","title":"A new view of radiation-induced cancer: integrating short- and long-term processes. Part II: second cancer risk estimation","display_name":"A new view of radiation-induced cancer: integrating short- and long-term processes. Part II: second cancer risk estimation","publication_year":2009,"publication_date":"2009-06-05","ids":{"openalex":"https://openalex.org/W2170654271","doi":"https://doi.org/10.1007/s00411-009-0231-2","mag":"2170654271","pmid":"https://pubmed.ncbi.nlm.nih.gov/19499238","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2714894"},"language":"en","primary_location":{"id":"doi:10.1007/s00411-009-0231-2","doi":"https://doi.org/10.1007/s00411-009-0231-2","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00411-009-0231-2","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00411-009-0231-2.pdf","source":{"id":"https://openalex.org/S152286864","display_name":"Radiation and Environmental Biophysics","issn_l":"0301-634X","issn":["0301-634X","1432-2099"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiation and Environmental Biophysics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s00411-009-0231-2.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044358814","display_name":"Igor Shuryak","orcid":"https://orcid.org/0000-0001-9314-5708","observed_orcids":["https://orcid.org/0000-0001-9314-5708"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Igor Shuryak","raw_affiliation_strings":["Center for Radiological Research, Columbia University Medical Center, New York, NY 10032, USA. ishuryak@gmail.com","Center for Radiological Research, Columbia University Medical Center, 630 West 168th St., New York, NY, 10032, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Radiological Research, Columbia University Medical Center, New York, NY 10032, USA. ishuryak@gmail.com","institution_ids":["https://openalex.org/I2799503643"]},{"raw_affiliation_string":"Center for Radiological Research, Columbia University Medical Center, 630 West 168th St., New York, NY, 10032, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082159954","display_name":"Philip Hahnfeldt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I3018163063","display_name":"St. Elizabeth's Medical Center","ror":"https://ror.org/00cr15z55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3018163063"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Philip Hahnfeldt","raw_affiliation_strings":["Caritas St. Elizabeth\u2019s Medical Center, Tufts University School of Medicine, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Caritas St. Elizabeth\u2019s Medical Center, Tufts University School of Medicine, Boston, MA, USA","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I3018163063"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034908463","display_name":"Lynn Hlatky","orcid":"https://orcid.org/0000-0002-2340-8119","observed_orcids":["https://orcid.org/0000-0002-2340-8119"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I3018163063","display_name":"St. Elizabeth's Medical Center","ror":"https://ror.org/00cr15z55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3018163063"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lynn Hlatky","raw_affiliation_strings":["Caritas St. Elizabeth\u2019s Medical Center, Tufts University School of Medicine, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Caritas St. Elizabeth\u2019s Medical Center, Tufts University School of Medicine, Boston, MA, USA","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I3018163063"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105986180","display_name":"Rainer K. Sachs","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rainer K. Sachs","raw_affiliation_strings":["Departments of Mathematics and Physics, University of California Berkeley, Berkeley, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Mathematics and Physics, University of California Berkeley, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048201953","display_name":"David J. Brenner","orcid":"https://orcid.org/0000-0002-0926-1210","observed_orcids":["https://orcid.org/0000-0002-0926-1210"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David J. Brenner","raw_affiliation_strings":["Center for Radiological Research, Columbia University Medical Center, 630 West 168th St., New York, NY, 10032, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Radiological Research, Columbia University Medical Center, 630 West 168th St., New York, NY, 10032, USA","institution_ids":["https://openalex.org/I2799503643"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5048201953"],"corresponding_institution_ids":["https://openalex.org/I2799503643"],"apc_list":{"value":3290,"currency":"USD","value_usd":3290},"apc_paid":{"value":3290,"currency":"USD","value_usd":3290},"fwci":5.5007,"has_fulltext":true,"cited_by_count":90,"citation_normalized_percentile":{"value":0.96106718,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":92,"max":99},"biblio":{"volume":"48","issue":"3","first_page":"275","last_page":"286"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.6523000001907349,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.6523000001907349,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.13269999623298645,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.09070000052452087,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.5540000200271606},{"id":"https://openalex.org/keywords/solid-tumors","display_name":"solid tumors","score":0.6129999756813049},{"id":"https://openalex.org/keywords/atomic-bomb-survivors","display_name":"atomic bomb survivors","score":0.8140000104904175},{"id":"https://openalex.org/keywords/cancer-incidence","display_name":"cancer incidence","score":0.6890000104904175},{"id":"https://openalex.org/keywords/radiotherapy-treatment-planning","display_name":"radiotherapy treatment planning","score":0.8579999804496765}],"concepts":[{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.728480875492096},{"id":"https://openalex.org/C2778738651","wikidata":"https://www.wikidata.org/wiki/Q16546687","display_name":"Novelty","level":2,"score":0.579088032245636},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5509183406829834},{"id":"https://openalex.org/C2780210213","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic cancer","level":3,"score":0.5322898030281067},{"id":"https://openalex.org/C2779761222","wikidata":"https://www.wikidata.org/wiki/Q826522","display_name":"Thyroid cancer","level":3,"score":0.5233684778213501},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.5012264251708984},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.4904148280620575},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.48613640666007996},{"id":"https://openalex.org/C2780352672","wikidata":"https://www.wikidata.org/wiki/Q504775","display_name":"Bladder cancer","level":3,"score":0.43292713165283203},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3473038077354431},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.34222841262817383},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2938728928565979},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.09546712040901184},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009381","descriptor_name":"Neoplasms, Radiation-Induced","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D009381","descriptor_name":"Neoplasms, Radiation-Induced","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D011878","descriptor_name":"Radiotherapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D011879","descriptor_name":"Radiotherapy Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017677","descriptor_name":"Age Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017741","descriptor_name":"Survivors","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D054043","descriptor_name":"Nuclear Weapons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":8,"locations":[{"id":"doi:10.1007/s00411-009-0231-2","doi":"https://doi.org/10.1007/s00411-009-0231-2","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00411-009-0231-2","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00411-009-0231-2.pdf","source":{"id":"https://openalex.org/S152286864","display_name":"Radiation and Environmental Biophysics","issn_l":"0301-634X","issn":["0301-634X","1432-2099"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiation and Environmental Biophysics","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:1866086","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2714894","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2714894","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2714894","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiat Environ Biophys","raw_type":"Text"},{"id":"pmid:19499238","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19499238","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiation and environmental biophysics","raw_type":"Journal Article"},{"id":"pmh:oai:osti.gov:1816642","doi":null,"is_oa":true,"landing_page_url":"https://www.osti.gov/biblio/1816642","pdf_url":"https://www.osti.gov/servlets/purl/1816642","source":{"id":"https://openalex.org/S4306402487","display_name":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I139351228","host_organization_name":"Office of Scientific and Technical Information","host_organization_lineage":["https://openalex.org/I139351228"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.357.8295","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.357.8295","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/d2/2f/Radiat_Environ_Biophys_2009_Aug_5_48(3)_275-286.tar.gz","raw_type":"text"},{"id":"pmh:oai:escholarship.org/ark:/13030/qt6r5597jj","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.org/uc/item/6r5597jj","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Radiation and Environmental Biophysics, vol 48, iss 3","raw_type":"article"},{"id":"pmh:qt6r5597jj","doi":null,"is_oa":false,"landing_page_url":"http://www.escholarship.org/uc/item/6r5597jj","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Shuryak, Igor; Hahnfeldt, Philip; Hlatky, Lynn; Sachs, Rainer K.; & Brenner, David J.(2009). A new view of radiation-induced cancer: integrating short- and long-term processes. Part II: second cancer risk estimation. Radiation and Environmental Biophysics, 48(3), pp 275-286. doi: 10.1007/s00411-009-0231-2. Retrieved from: http://www.escholarship.org/uc/item/6r5597jj","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1007/s00411-009-0231-2","doi":"https://doi.org/10.1007/s00411-009-0231-2","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00411-009-0231-2","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00411-009-0231-2.pdf","source":{"id":"https://openalex.org/S152286864","display_name":"Radiation and Environmental Biophysics","issn_l":"0301-634X","issn":["0301-634X","1432-2099"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiation and Environmental Biophysics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G164325845","display_name":"MODELING THE INTERALATIONS AMONG RADIATION-INDUCED BYSTANDER EFFECTS, GENOMIC INSTABILITY AND CANCER","funder_award_id":"FG02-03ER63668","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G222768804","display_name":null,"funder_award_id":"DE\u2010FG02\u2010","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G2820271166","display_name":"Radiological Research Accelerator Facility (RARAF)","funder_award_id":"P41EB002033","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G2958910270","display_name":null,"funder_award_id":"CA-78496","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G3816247084","display_name":null,"funder_award_id":"5T32-CA009529","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4122887522","display_name":"Qualifying effectiveness of angiogenic inhibitors","funder_award_id":"R01CA078496","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4372071640","display_name":"Radiation Bystander Effects: Mechanisms","funder_award_id":"P01CA049062","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G5719255924","display_name":null,"funder_award_id":"T32\u2010CA009529","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6455627660","display_name":"SOLID TUMOR RISK ESTIMATION: INCORPORATING INTERCELLULAR EFFECTS","funder_award_id":"NNJ06HA28G","funder_id":"https://openalex.org/F4320306101","funder_display_name":"National Aeronautics and Space Administration"},{"id":"https://openalex.org/G7135164121","display_name":"Cancer Epidemiology, Biostatistics and Environmental Sciences","funder_award_id":"5t32ca009529-25","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G783148536","display_name":"SOLID TUMOR RISK ESTIMATION: INCORPORATING INTERCELLULAR INTERACTION EFFECTS","funder_award_id":"NNJ04HJ12G","funder_id":"https://openalex.org/F4320306101","funder_display_name":"National Aeronautics and Space Administration"}],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320306101","display_name":"National Aeronautics and Space Administration","ror":"https://ror.org/027ka1x80"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2170654271.pdf","grobid_xml":"https://content.openalex.org/works/W2170654271.grobid-xml"},"referenced_works_count":60,"referenced_works":["https://openalex.org/W1899186548","https://openalex.org/W1964918642","https://openalex.org/W1968193756","https://openalex.org/W1974417755","https://openalex.org/W1975454577","https://openalex.org/W1978878319","https://openalex.org/W1980020949","https://openalex.org/W1980168352","https://openalex.org/W1983415507","https://openalex.org/W1985875228","https://openalex.org/W1990278794","https://openalex.org/W1999639264","https://openalex.org/W2004764331","https://openalex.org/W2005133500","https://openalex.org/W2021200503","https://openalex.org/W2022054806","https://openalex.org/W2026175145","https://openalex.org/W2032029477","https://openalex.org/W2033177603","https://openalex.org/W2047456078","https://openalex.org/W2053777605","https://openalex.org/W2066861312","https://openalex.org/W2069987559","https://openalex.org/W2071007497","https://openalex.org/W2074963996","https://openalex.org/W2080839610","https://openalex.org/W2094560161","https://openalex.org/W2097691703","https://openalex.org/W2101087025","https://openalex.org/W2104375875","https://openalex.org/W2106193652","https://openalex.org/W2108539626","https://openalex.org/W2109610417","https://openalex.org/W2113519807","https://openalex.org/W2117285637","https://openalex.org/W2118553111","https://openalex.org/W2124435581","https://openalex.org/W2129146771","https://openalex.org/W2130494212","https://openalex.org/W2130803751","https://openalex.org/W2136761623","https://openalex.org/W2145932964","https://openalex.org/W2147619893","https://openalex.org/W2149642768","https://openalex.org/W2160226244","https://openalex.org/W2161222251","https://openalex.org/W2163292580","https://openalex.org/W2164524585","https://openalex.org/W2166800480","https://openalex.org/W2168273060","https://openalex.org/W2168750813","https://openalex.org/W2168866633","https://openalex.org/W2180097032","https://openalex.org/W2180741372","https://openalex.org/W2292882248","https://openalex.org/W2412450650","https://openalex.org/W2796837256","https://openalex.org/W3004157836","https://openalex.org/W4248142848","https://openalex.org/W4256153680"],"related_works":["https://openalex.org/W2062515960","https://openalex.org/W2017120882","https://openalex.org/W7096199921","https://openalex.org/W2117827152","https://openalex.org/W2053000325","https://openalex.org/W2332213152","https://openalex.org/W7100913353","https://openalex.org/W2402687574","https://openalex.org/W7096256323","https://openalex.org/W2118553111"],"abstract_inverted_index":{"As":[0],"the":[1,17,25,38,63,91,98,135],"number":[2],"of":[3,8,27,62,75],"cancer":[4,11,55,103,132,147],"survivors":[5],"grows,":[6],"prediction":[7],"radiotherapy-induced":[9,120],"second":[10,54,121,146],"risks":[12,26,56],"becomes":[13],"increasingly":[14],"important.":[15],"Because":[16],"latency":[18],"period":[19],"for":[20,57],"solid":[21,102],"tumors":[22],"is":[23,65],"long,":[24],"recently":[28],"introduced":[29],"radiotherapy":[30,86,141],"protocols":[31],"are":[32],"not":[33],"yet":[34],"directly":[35],"measurable.":[36],"In":[37],"accompanying":[39],"article,":[40],"we":[41,96],"presented":[42],"a":[43,70],"new":[44],"biologically":[45],"based":[46],"mathematical":[47],"model,":[48],"which,":[49],"in":[50],"principle,":[51],"can":[52,137],"estimate":[53],"any":[58],"protocol.":[59],"The":[60],"novelty":[61],"model":[64,99,136],"that":[66],"it":[67],"integrates,":[68],"into":[69,140],"single":[71],"formalism,":[72],"mechanistic":[73],"analyses":[74],"pre-malignant":[76],"cell":[77],"dynamics":[78],"on":[79,119,123,129],"two":[80],"different":[81],"time":[82],"scales:":[83],"short-term":[84],"during":[85,90],"and":[87,115,128],"recovery;":[88],"long-term":[89],"entire":[92],"life":[93],"span.":[94],"Here,":[95],"apply":[97],"to":[100],"nine":[101],"types":[104],"(stomach,":[105],"lung,":[106],"colon,":[107],"rectal,":[108],"pancreatic,":[109],"bladder,":[110],"breast,":[111],"central":[112],"nervous":[113],"system,":[114],"thyroid)":[116],"using":[117],"data":[118],"malignancies,":[122],"Japanese":[124],"atomic":[125],"bomb":[126],"survivors,":[127],"background":[130],"US":[131],"incidence.":[133],"Potentially,":[134],"be":[138],"incorporated":[139],"treatment":[142],"planning":[143],"algorithms,":[144],"adding":[145],"risk":[148],"as":[149],"an":[150],"optimization":[151],"criterion.":[152]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}