{"id":"https://openalex.org/W2170299131","doi":"https://doi.org/10.1517/14622416.6.3.211","title":"Pharmacogenetics and Nicotine Addiction Treatment","display_name":"Pharmacogenetics and Nicotine Addiction Treatment","publication_year":2005,"publication_date":"2005-04-01","ids":{"openalex":"https://openalex.org/W2170299131","doi":"https://doi.org/10.1517/14622416.6.3.211","mag":"2170299131","pmid":"https://pubmed.ncbi.nlm.nih.gov/16013953"},"language":"en","primary_location":{"id":"doi:10.1517/14622416.6.3.211","doi":"https://doi.org/10.1517/14622416.6.3.211","is_oa":false,"landing_page_url":"https://doi.org/10.1517/14622416.6.3.211","pdf_url":null,"source":{"id":"https://openalex.org/S190377370","display_name":"Pharmacogenomics","issn_l":"1462-2416","issn":["1462-2416","1744-8042"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321119","host_organization_name":"Future Medicine","host_organization_lineage":["https://openalex.org/P4310321119"],"host_organization_lineage_names":["Future Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacogenomics","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006758334","display_name":"Marcus Robert Munafo","orcid":"https://orcid.org/0000-0002-4049-993X","observed_orcids":["https://orcid.org/0000-0002-4049-993X","https://orcid.org/0000-0002-4793-6290"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Marcus R Munaf\u00f2","raw_affiliation_strings":["University of Bristol, Department of Experimental Psychology, 8 Woodland Road, Bristol, BS8 ITN, UK","University of Bristol, Department of Experimental Psychology, 8 Woodland Road, Bristol, BS8 ITN, UK. E-mail:"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Bristol, Department of Experimental Psychology, 8 Woodland Road, Bristol, BS8 ITN, UK","institution_ids":["https://openalex.org/I36234482"]},{"raw_affiliation_string":"University of Bristol, Department of Experimental Psychology, 8 Woodland Road, Bristol, BS8 ITN, UK. E-mail:","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065583926","display_name":"Alexandra E. Shields","orcid":"https://orcid.org/0000-0002-3706-1718","observed_orcids":["https://orcid.org/0000-0002-3706-1718","https://orcid.org/0009-0007-6658-0369"]},"institutions":[{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexandra E Shields","raw_affiliation_strings":["Georgetown University, Health Policy Institute, Georgetown Public Policy Institute, 2233 Wisconsin Ave, NW, Suite 525, Washington DC 20007, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Georgetown University, Health Policy Institute, Georgetown Public Policy Institute, 2233 Wisconsin Ave, NW, Suite 525, Washington DC 20007, USA","institution_ids":["https://openalex.org/I184565670"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012998944","display_name":"Wade H. Berrettini","orcid":"https://orcid.org/0000-0001-8445-5165","observed_orcids":["https://orcid.org/0000-0001-8445-5165"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wade H Berrettini","raw_affiliation_strings":["University of Pennsylvania, Department of Psychiatry, Center for Neurobiology and Behavior, Room 111 Clinical Research Building, 415 Curie Bvd, PA19104, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pennsylvania, Department of Psychiatry, Center for Neurobiology and Behavior, Room 111 Clinical Research Building, 415 Curie Bvd, PA19104, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017029517","display_name":"Freda Patterson","orcid":"https://orcid.org/0000-0001-6561-3092","observed_orcids":["https://orcid.org/0000-0001-6561-3092"]},"institutions":[{"id":"https://openalex.org/I4390039297","display_name":"Abramson Cancer Center","ror":"https://ror.org/01hvpjq66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210143392","https://openalex.org/I4390039297"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Freda Patterson","raw_affiliation_strings":["University of Pennsylvania, Transdisciplinary Tobacco Use Research Center, Abramson Cancer Center, 3535 Market St, Suite 4100, PA19104, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pennsylvania, Transdisciplinary Tobacco Use Research Center, Abramson Cancer Center, 3535 Market St, Suite 4100, PA19104, USA","institution_ids":["https://openalex.org/I4390039297","https://openalex.org/I79576946"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061725200","display_name":"Caryn E. Lerman","orcid":"https://orcid.org/0000-0002-7553-8724","observed_orcids":["https://orcid.org/0000-0002-7553-8724"]},"institutions":[{"id":"https://openalex.org/I4390039297","display_name":"Abramson Cancer Center","ror":"https://ror.org/01hvpjq66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210143392","https://openalex.org/I4390039297"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Caryn Lerman","raw_affiliation_strings":["University of Pennsylvania, Transdisciplinary Tobacco Use Research Center, Abramson Cancer Center, 3535 Market St, Suite 4100, PA19104, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pennsylvania, Transdisciplinary Tobacco Use Research Center, Abramson Cancer Center, 3535 Market St, Suite 4100, PA19104, USA","institution_ids":["https://openalex.org/I4390039297","https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.6276,"has_fulltext":false,"cited_by_count":60,"citation_normalized_percentile":{"value":0.83822297,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"6","issue":"3","first_page":"211","last_page":"223"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.020500000566244125,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pharmacogenetics","display_name":"pharmacogenetics","score":0.9829999804496765},{"id":"https://openalex.org/keywords/nicotine-dependence","display_name":"nicotine dependence","score":0.9760000109672546},{"id":"https://openalex.org/keywords/smoking-cessation","display_name":"smoking cessation","score":0.9589999914169312},{"id":"https://openalex.org/keywords/nicotine-replacement-therapy","display_name":"nicotine replacement therapy","score":0.9980000257492065},{"id":"https://openalex.org/keywords/bupropion","display_name":"bupropion","score":0.996999979019165},{"id":"https://openalex.org/keywords/personalized-medicine","display_name":"personalized medicine","score":0.6650000214576721},{"id":"https://openalex.org/keywords/behavioral-support","display_name":"behavioral support","score":0.699999988079071},{"id":"https://openalex.org/keywords/clinical-translation","display_name":"clinical translation","score":0.5350000262260437},{"id":"https://openalex.org/keywords/genetic-testing-ethics","display_name":"ethics of genetic testing","score":0.531000018119812}],"concepts":[{"id":"https://openalex.org/C55775858","wikidata":"https://www.wikidata.org/wiki/Q1152227","display_name":"Pharmacogenetics","level":4,"score":0.8187258839607239},{"id":"https://openalex.org/C2780478649","wikidata":"https://www.wikidata.org/wiki/Q1189783","display_name":"Nicotine replacement therapy","level":3,"score":0.7652289867401123},{"id":"https://openalex.org/C2779908668","wikidata":"https://www.wikidata.org/wiki/Q834280","display_name":"Bupropion","level":3,"score":0.7633737325668335},{"id":"https://openalex.org/C48856860","wikidata":"https://www.wikidata.org/wiki/Q12029","display_name":"Addiction","level":2,"score":0.7354345917701721},{"id":"https://openalex.org/C2777843972","wikidata":"https://www.wikidata.org/wiki/Q2462253","display_name":"Smoking cessation","level":2,"score":0.7312985062599182},{"id":"https://openalex.org/C2779547902","wikidata":"https://www.wikidata.org/wiki/Q28086552","display_name":"Nicotine","level":2,"score":0.6784324645996094},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5867490172386169},{"id":"https://openalex.org/C2778647338","wikidata":"https://www.wikidata.org/wiki/Q18553444","display_name":"Nicotine dependence","level":3,"score":0.5245419144630432},{"id":"https://openalex.org/C2909683868","wikidata":"https://www.wikidata.org/wiki/Q28086552","display_name":"Nicotine Addiction","level":3,"score":0.511751651763916},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.43419817090034485},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4268333911895752},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.35659652948379517},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3304838538169861},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.2497546672821045},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.060677558183670044},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010597","descriptor_name":"Pharmacogenetics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010597","descriptor_name":"Pharmacogenetics","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D010597","descriptor_name":"Pharmacogenetics","qualifier_ui":"Q000941","qualifier_name":"ethics","is_major_topic":false},{"descriptor_ui":"D014029","descriptor_name":"Tobacco Use Disorder","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D014029","descriptor_name":"Tobacco Use Disorder","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016540","descriptor_name":"Smoking Cessation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016642","descriptor_name":"Bupropion","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1517/14622416.6.3.211","doi":"https://doi.org/10.1517/14622416.6.3.211","is_oa":false,"landing_page_url":"https://doi.org/10.1517/14622416.6.3.211","pdf_url":null,"source":{"id":"https://openalex.org/S190377370","display_name":"Pharmacogenomics","issn_l":"1462-2416","issn":["1462-2416","1744-8042"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321119","host_organization_name":"Future Medicine","host_organization_lineage":["https://openalex.org/P4310321119"],"host_organization_lineage_names":["Future Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacogenomics","raw_type":"journal-article"},{"id":"pmid:16013953","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16013953","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacogenomics","raw_type":"Journal Article"},{"id":"pmh:oai:research-information.bris.ac.uk:openaire_cris_publications/4c36fd1e-9203-4cbf-bcd6-fa1d8877f380","doi":null,"is_oa":false,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/4c36fd1e-9203-4cbf-bcd6-fa1d8877f380","pdf_url":null,"source":{"id":"https://openalex.org/S4306400895","display_name":"Bristol Research (University of Bristol)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I36234482","host_organization_name":"University of Bristol","host_organization_lineage":["https://openalex.org/I36234482"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Munafo, MR, Shields, AE, Berrettini, WH, Patterson, F & Lerman, C 2005, 'Pharmacogenetics and nicotine addiction treatment', Pharmacogenomics, vol. 6, pp. 211 - 223. https://doi.org/10.1517/14622416.6.3.211","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:research-information.bris.ac.uk:publications/4c36fd1e-9203-4cbf-bcd6-fa1d8877f380","doi":null,"is_oa":false,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/4c36fd1e-9203-4cbf-bcd6-fa1d8877f380","pdf_url":null,"source":{"id":"https://openalex.org/S7407055359","display_name":"Explore Bristol Research","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Munafo, MR, Shields, AE, Berrettini, WH, Patterson, F & Lerman, C 2005, 'Pharmacogenetics and nicotine addiction treatment', Pharmacogenomics, vol. 6, pp. 211 - 223. https://doi.org/10.1517/14622416.6.3.211","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306095","display_name":"American Cancer Society","ror":"https://ror.org/02e463172"},{"id":"https://openalex.org/F4320306139","display_name":"Robert Wood Johnson Foundation","ror":"https://ror.org/02ymmdj85"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":108,"referenced_works":["https://openalex.org/W59963526","https://openalex.org/W108371853","https://openalex.org/W293149033","https://openalex.org/W626715752","https://openalex.org/W1494665478","https://openalex.org/W1568198343","https://openalex.org/W1582615617","https://openalex.org/W1588469854","https://openalex.org/W1680855902","https://openalex.org/W1944826763","https://openalex.org/W1955803833","https://openalex.org/W1963923329","https://openalex.org/W1964763628","https://openalex.org/W1964979617","https://openalex.org/W1965248635","https://openalex.org/W1966042288","https://openalex.org/W1970203156","https://openalex.org/W1974317576","https://openalex.org/W1974853174","https://openalex.org/W1976056426","https://openalex.org/W1981891257","https://openalex.org/W1985796466","https://openalex.org/W1986652078","https://openalex.org/W1988560875","https://openalex.org/W1989309889","https://openalex.org/W1989634408","https://openalex.org/W1990139289","https://openalex.org/W1990578886","https://openalex.org/W1995164644","https://openalex.org/W2002368082","https://openalex.org/W2003920090","https://openalex.org/W2006215966","https://openalex.org/W2011220564","https://openalex.org/W2012172073","https://openalex.org/W2012618914","https://openalex.org/W2012743573","https://openalex.org/W2013413208","https://openalex.org/W2013488381","https://openalex.org/W2015797791","https://openalex.org/W2018852061","https://openalex.org/W2021089766","https://openalex.org/W2026746825","https://openalex.org/W2028564423","https://openalex.org/W2029650496","https://openalex.org/W2029913530","https://openalex.org/W2030965982","https://openalex.org/W2042182057","https://openalex.org/W2044116486","https://openalex.org/W2044847088","https://openalex.org/W2045031661","https://openalex.org/W2045573261","https://openalex.org/W2048511472","https://openalex.org/W2048963574","https://openalex.org/W2049561873","https://openalex.org/W2050441476","https://openalex.org/W2051362493","https://openalex.org/W2055722346","https://openalex.org/W2056096497","https://openalex.org/W2056964947","https://openalex.org/W2060137259","https://openalex.org/W2060596420","https://openalex.org/W2063586570","https://openalex.org/W2065841438","https://openalex.org/W2066669827","https://openalex.org/W2066871625","https://openalex.org/W2073891038","https://openalex.org/W2075362165","https://openalex.org/W2078129420","https://openalex.org/W2080210743","https://openalex.org/W2080382785","https://openalex.org/W2081438909","https://openalex.org/W2090240371","https://openalex.org/W2090501717","https://openalex.org/W2092071349","https://openalex.org/W2111778606","https://openalex.org/W2112696084","https://openalex.org/W2116329478","https://openalex.org/W2118061336","https://openalex.org/W2119773879","https://openalex.org/W2120483845","https://openalex.org/W2126832515","https://openalex.org/W2127809121","https://openalex.org/W2130682362","https://openalex.org/W2132992773","https://openalex.org/W2138419072","https://openalex.org/W2139002433","https://openalex.org/W2141151785","https://openalex.org/W2145557211","https://openalex.org/W2145579259","https://openalex.org/W2146220657","https://openalex.org/W2150718657","https://openalex.org/W2157144772","https://openalex.org/W2158112485","https://openalex.org/W2158294624","https://openalex.org/W2162418791","https://openalex.org/W2169766785","https://openalex.org/W2170397982","https://openalex.org/W2170876712","https://openalex.org/W2171300131","https://openalex.org/W2193494830","https://openalex.org/W2243222317","https://openalex.org/W2254424210","https://openalex.org/W2316278005","https://openalex.org/W2323234292","https://openalex.org/W2418261693","https://openalex.org/W2463861392","https://openalex.org/W4240191731","https://openalex.org/W4245282005"],"related_works":["https://openalex.org/W1523775502","https://openalex.org/W2101136323","https://openalex.org/W2144006733","https://openalex.org/W2028781751","https://openalex.org/W6991238923","https://openalex.org/W7100259735","https://openalex.org/W2011876869","https://openalex.org/W1991748802","https://openalex.org/W2923063686","https://openalex.org/W2329594816"],"abstract_inverted_index":{"This":[0],"review":[1],"focuses":[2],"on":[3,14,74],"the":[4,83],"current":[5],"status":[6],"of,":[7],"and":[8,17,27,32,54,81,98],"future":[9],"directions":[10],"for,":[11],"pharmacogenetic":[12],"research":[13,73,107],"nicotine":[15,24,30],"dependence":[16],"smoking":[18,33],"cessation":[19,34],"treatment.":[20],"Pharmacological":[21],"treatment":[22,87],"involving":[23],"replacement":[25],"therapy":[26],"bupropion":[28],"for":[29,85],"addiction":[31],"has":[35],"been":[36],"shown":[37],"to":[38,68,89],"be":[39,62,103],"efficacious":[40],"when":[41],"provided":[42],"in":[43,78],"combination":[44],"with":[45],"behavioral":[46],"support.":[47],"Cessation":[48],"rates":[49,60],"remain":[50],"somewhat":[51],"modest,":[52],"however,":[53],"one":[55],"possibility":[56],"is":[57,91,108],"that":[58,101],"success":[59],"may":[61],"enhanced":[63],"by":[64],"offering":[65],"treatments":[66],"tailored":[67,88],"an":[69],"individual's":[70],"genotype.":[71],"Nonetheless,":[72],"this":[75],"issue":[76],"remains":[77],"its":[79],"infancy,":[80],"although":[82],"scope":[84],"individualized":[86],"genotype":[90],"promising,":[92],"there":[93],"are":[94],"substantial":[95],"practical,":[96],"ethical":[97],"social":[99],"considerations":[100],"must":[102],"addressed":[104],"before":[105],"such":[106],"translated":[109],"into":[110],"clinical":[111],"practice.":[112]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
