{"id":"https://openalex.org/W2170205288","doi":"https://doi.org/10.1016/j.hrthm.2010.04.015","title":"Genetic variants and ECG pattern variability in long QT syndrome: How far are we?","display_name":"Genetic variants and ECG pattern variability in long QT syndrome: How far are we?","publication_year":2010,"publication_date":"2010-04-19","ids":{"openalex":"https://openalex.org/W2170205288","doi":"https://doi.org/10.1016/j.hrthm.2010.04.015","mag":"2170205288","pmid":"https://pubmed.ncbi.nlm.nih.gov/20406697"},"language":"en","primary_location":{"id":"doi:10.1016/j.hrthm.2010.04.015","doi":"https://doi.org/10.1016/j.hrthm.2010.04.015","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.hrthm.2010.04.015","pdf_url":null,"source":{"id":"https://openalex.org/S163651451","display_name":"Heart Rhythm","issn_l":"1547-5271","issn":["1547-5271","1556-3871"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Heart Rhythm","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004240247","display_name":"Matteo Vatta","orcid":"https://orcid.org/0000-0003-0962-8163","observed_orcids":["https://orcid.org/0000-0003-0962-8163","https://orcid.org/0000-0002-1742-7719"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I4210147586","display_name":"Texas Children's Hospital","ror":"https://ror.org/05cz92x43","country_code":"US","type":"funder","lineage":["https://openalex.org/I4210147586"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Matteo Vatta","raw_affiliation_strings":["Departments of Pediatrics (Cardiology) and Department of Molecular Physiology and Biophysics, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics (Cardiology) and Department of Molecular Physiology and Biophysics, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas","institution_ids":["https://openalex.org/I181547552","https://openalex.org/I4210147586"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5004240247"],"corresponding_institution_ids":["https://openalex.org/I181547552","https://openalex.org/I4210147586"],"apc_list":{"value":4790,"currency":"USD","value_usd":4790},"apc_paid":null,"fwci":0.2195,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.67784093,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"7","issue":"7","first_page":"904","last_page":"905"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/long-qt-syndrome","display_name":"long QT syndrome","score":1.0},{"id":"https://openalex.org/keywords/genetic-variants","display_name":"genetic variants","score":0.9179999828338623},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9359999895095825},{"id":"https://openalex.org/keywords/t-wave-morphology","display_name":"T-wave morphology","score":0.9369999766349792},{"id":"https://openalex.org/keywords/qt-interval","display_name":"QT interval","score":0.7039999961853027},{"id":"https://openalex.org/keywords/cardiac-ion-channels","display_name":"cardiac ion channels","score":0.7889999747276306},{"id":"https://openalex.org/keywords/nos1ap","display_name":"NOS1AP","score":0.9750000238418579},{"id":"https://openalex.org/keywords/ventricular-repolarization","display_name":"ventricular repolarization","score":0.9599999785423279},{"id":"https://openalex.org/keywords/sudden-cardiac-death","display_name":"sudden cardiac death","score":0.8820000290870667},{"id":"https://openalex.org/keywords/torsades-de-pointes","display_name":"torsades de pointes","score":0.7950000166893005},{"id":"https://openalex.org/keywords/syncope","display_name":"syncope","score":0.6380000114440918},{"id":"https://openalex.org/keywords/beta-blockers","display_name":"beta-blockers","score":0.6140000224113464},{"id":"https://openalex.org/keywords/implantable-cardioverter-defibrillator","display_name":"implantable cardioverter-defibrillator","score":0.9959999918937683}],"concepts":[{"id":"https://openalex.org/C118441451","wikidata":"https://www.wikidata.org/wiki/Q12074763","display_name":"QT interval","level":2,"score":0.8656660914421082},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8084450960159302},{"id":"https://openalex.org/C2779703243","wikidata":"https://www.wikidata.org/wiki/Q653924","display_name":"Long QT syndrome","level":3,"score":0.6953790187835693},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.675818920135498},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6672357320785522},{"id":"https://openalex.org/C2775935837","wikidata":"https://www.wikidata.org/wiki/Q202837","display_name":"Sudden cardiac death","level":2,"score":0.6163510084152222},{"id":"https://openalex.org/C2780486423","wikidata":"https://www.wikidata.org/wiki/Q1625433","display_name":"Torsades de pointes","level":3,"score":0.5958949327468872},{"id":"https://openalex.org/C2779578097","wikidata":"https://www.wikidata.org/wiki/Q1484058","display_name":"Short QT syndrome","level":4,"score":0.45408040285110474}],"mesh":[{"descriptor_ui":"D000072237","descriptor_name":"ERG1 Potassium Channel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008133","descriptor_name":"Long QT Syndrome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D048868","descriptor_name":"Adaptor Proteins, Signal Transducing","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D051638","descriptor_name":"Ether-A-Go-Go Potassium Channels","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.hrthm.2010.04.015","doi":"https://doi.org/10.1016/j.hrthm.2010.04.015","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.hrthm.2010.04.015","pdf_url":null,"source":{"id":"https://openalex.org/S163651451","display_name":"Heart Rhythm","issn_l":"1547-5271","issn":["1547-5271","1556-3871"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Heart Rhythm","raw_type":"journal-article"},{"id":"pmid:20406697","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20406697","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Heart rhythm","raw_type":"Editorial"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1968818236","https://openalex.org/W1971116816","https://openalex.org/W1973522972","https://openalex.org/W1984313043","https://openalex.org/W1984518423","https://openalex.org/W1987908892","https://openalex.org/W2009177696","https://openalex.org/W2014588136","https://openalex.org/W2025805823","https://openalex.org/W2026795180","https://openalex.org/W2054469718","https://openalex.org/W2055802416","https://openalex.org/W2073264109","https://openalex.org/W2080271062","https://openalex.org/W2082275497","https://openalex.org/W2085199612","https://openalex.org/W2115157987","https://openalex.org/W2116008876","https://openalex.org/W2124718950","https://openalex.org/W2128029952","https://openalex.org/W2152031596"],"related_works":["https://openalex.org/W2045425546","https://openalex.org/W2901215639","https://openalex.org/W4404846011","https://openalex.org/W3143684551","https://openalex.org/W2036587921","https://openalex.org/W2068483283","https://openalex.org/W2141892120","https://openalex.org/W2411506151","https://openalex.org/W2337442640","https://openalex.org/W1929899014"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}