{"id":"https://openalex.org/W2170097301","doi":"https://doi.org/10.1111/j.1872-034x.2009.00614.x","title":"Amino acid imbalance in patients with chronic liver diseases","display_name":"Amino acid imbalance in patients with chronic liver diseases","publication_year":2010,"publication_date":"2010-03-04","ids":{"openalex":"https://openalex.org/W2170097301","doi":"https://doi.org/10.1111/j.1872-034x.2009.00614.x","mag":"2170097301","pmid":"https://pubmed.ncbi.nlm.nih.gov/20236360"},"language":"en","primary_location":{"id":"doi:10.1111/j.1872-034x.2009.00614.x","doi":"https://doi.org/10.1111/j.1872-034x.2009.00614.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1872-034x.2009.00614.x","pdf_url":null,"source":{"id":"https://openalex.org/S110399111","display_name":"Hepatology Research","issn_l":"1386-6346","issn":["1386-6346","1872-034X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatology Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060892525","display_name":"Kojiro Michitaka","orcid":"https://orcid.org/0000-0001-8182-4578","observed_orcids":["https://orcid.org/0000-0001-8182-4578"]},"institutions":[{"id":"https://openalex.org/I4210145364","display_name":"Ehime Prefectural Central Hospital","ror":"https://ror.org/03c648b36","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210145364"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Kojiro Michitaka","raw_affiliation_strings":["Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama","institution_ids":["https://openalex.org/I4210145364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040485741","display_name":"Atsushi Hiraoka","orcid":"https://orcid.org/0000-0003-1989-0480","observed_orcids":["https://orcid.org/0000-0003-1989-0480"]},"institutions":[{"id":"https://openalex.org/I4210145364","display_name":"Ehime Prefectural Central Hospital","ror":"https://ror.org/03c648b36","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210145364"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Atsushi Hiraoka","raw_affiliation_strings":["Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,","institution_ids":["https://openalex.org/I4210145364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025898095","display_name":"Misaki Kume","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145364","display_name":"Ehime Prefectural Central Hospital","ror":"https://ror.org/03c648b36","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210145364"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Misaki Kume","raw_affiliation_strings":["Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,","institution_ids":["https://openalex.org/I4210145364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110518772","display_name":"Takahide Uehara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145364","display_name":"Ehime Prefectural Central Hospital","ror":"https://ror.org/03c648b36","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210145364"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takahide Uehara","raw_affiliation_strings":["Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,","institution_ids":["https://openalex.org/I4210145364"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Satoshi Hidaka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145364","display_name":"Ehime Prefectural Central Hospital","ror":"https://ror.org/03c648b36","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210145364"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Satoshi Hidaka","raw_affiliation_strings":["Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,","institution_ids":["https://openalex.org/I4210145364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101598816","display_name":"Tomoyuki Ninomiya","orcid":"https://orcid.org/0000-0002-9949-0446","observed_orcids":["https://orcid.org/0000-0002-9949-0446"]},"institutions":[{"id":"https://openalex.org/I4210145364","display_name":"Ehime Prefectural Central Hospital","ror":"https://ror.org/03c648b36","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210145364"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomoyuki Ninomiya","raw_affiliation_strings":["Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,","institution_ids":["https://openalex.org/I4210145364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080413604","display_name":"Aki Hasebe","orcid":"https://orcid.org/0000-0001-5926-4148","observed_orcids":["https://orcid.org/0000-0001-5926-4148"]},"institutions":[{"id":"https://openalex.org/I4210145364","display_name":"Ehime Prefectural Central Hospital","ror":"https://ror.org/03c648b36","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210145364"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Aki Hasebe","raw_affiliation_strings":["Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,","institution_ids":["https://openalex.org/I4210145364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110767809","display_name":"Yasunao Miyamoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145364","display_name":"Ehime Prefectural Central Hospital","ror":"https://ror.org/03c648b36","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210145364"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasunao Miyamoto","raw_affiliation_strings":["Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,","institution_ids":["https://openalex.org/I4210145364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019337463","display_name":"Misa Ichiryu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145364","display_name":"Ehime Prefectural Central Hospital","ror":"https://ror.org/03c648b36","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210145364"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Misa Ichiryu","raw_affiliation_strings":["Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,","institution_ids":["https://openalex.org/I4210145364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023729344","display_name":"Tetsuya Tanihira","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145364","display_name":"Ehime Prefectural Central Hospital","ror":"https://ror.org/03c648b36","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210145364"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tetsuya Tanihira","raw_affiliation_strings":["Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,","institution_ids":["https://openalex.org/I4210145364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111860370","display_name":"Hiromasa Nakahara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145364","display_name":"Ehime Prefectural Central Hospital","ror":"https://ror.org/03c648b36","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210145364"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiromasa Nakahara","raw_affiliation_strings":["Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,","institution_ids":["https://openalex.org/I4210145364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025980433","display_name":"Hironori Ochi","orcid":"https://orcid.org/0009-0002-1961-0899","observed_orcids":["https://orcid.org/0009-0002-1961-0899"]},"institutions":[{"id":"https://openalex.org/I4210145364","display_name":"Ehime Prefectural Central Hospital","ror":"https://ror.org/03c648b36","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210145364"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hironori Ochi","raw_affiliation_strings":["Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,","institution_ids":["https://openalex.org/I4210145364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030042299","display_name":"Atsushi Tanabe","orcid":"https://orcid.org/0000-0001-7651-3943","observed_orcids":["https://orcid.org/0000-0001-7651-3943"]},"institutions":[{"id":"https://openalex.org/I4210145364","display_name":"Ehime Prefectural Central Hospital","ror":"https://ror.org/03c648b36","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210145364"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Atsushi Tanabe","raw_affiliation_strings":["Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama,","institution_ids":["https://openalex.org/I4210145364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103943731","display_name":"Kazuhiro Uesugi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I43545212","display_name":"Ehime University","ror":"https://ror.org/017hkng22","country_code":"JP","type":"education","lineage":["https://openalex.org/I43545212"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuhiro Uesugi","raw_affiliation_strings":["Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan","institution_ids":["https://openalex.org/I43545212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101400205","display_name":"Yoshio Tokumoto","orcid":"https://orcid.org/0000-0003-3008-691X","observed_orcids":["https://orcid.org/0000-0003-3008-691X"]},"institutions":[{"id":"https://openalex.org/I43545212","display_name":"Ehime University","ror":"https://ror.org/017hkng22","country_code":"JP","type":"education","lineage":["https://openalex.org/I43545212"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshio Tokumoto","raw_affiliation_strings":["Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan","institution_ids":["https://openalex.org/I43545212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020528111","display_name":"Toshie Mashiba","orcid":"https://orcid.org/0000-0002-4377-4829","observed_orcids":["https://orcid.org/0000-0002-4377-4829"]},"institutions":[{"id":"https://openalex.org/I43545212","display_name":"Ehime University","ror":"https://ror.org/017hkng22","country_code":"JP","type":"education","lineage":["https://openalex.org/I43545212"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshie Mashiba","raw_affiliation_strings":["Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan","institution_ids":["https://openalex.org/I43545212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075913064","display_name":"Masanori Abe","orcid":"https://orcid.org/0000-0003-4489-9102","observed_orcids":["https://orcid.org/0000-0003-4489-9102"]},"institutions":[{"id":"https://openalex.org/I43545212","display_name":"Ehime University","ror":"https://ror.org/017hkng22","country_code":"JP","type":"education","lineage":["https://openalex.org/I43545212"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masanori Abe","raw_affiliation_strings":["Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan","institution_ids":["https://openalex.org/I43545212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035134420","display_name":"Yoichi Hiasa","orcid":"https://orcid.org/0000-0003-4117-339X","observed_orcids":["https://orcid.org/0000-0003-4117-339X"]},"institutions":[{"id":"https://openalex.org/I43545212","display_name":"Ehime University","ror":"https://ror.org/017hkng22","country_code":"JP","type":"education","lineage":["https://openalex.org/I43545212"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoichi Hiasa","raw_affiliation_strings":["Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan","institution_ids":["https://openalex.org/I43545212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087484635","display_name":"Bunzo Matsuura","orcid":"https://orcid.org/0000-0001-7815-2512","observed_orcids":["https://orcid.org/0000-0001-7815-2512"]},"institutions":[{"id":"https://openalex.org/I43545212","display_name":"Ehime University","ror":"https://ror.org/017hkng22","country_code":"JP","type":"education","lineage":["https://openalex.org/I43545212"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Bunzo Matsuura","raw_affiliation_strings":["Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan","institution_ids":["https://openalex.org/I43545212"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110518771","display_name":"Morikazu Onji","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I43545212","display_name":"Ehime University","ror":"https://ror.org/017hkng22","country_code":"JP","type":"education","lineage":["https://openalex.org/I43545212"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Morikazu Onji","raw_affiliation_strings":["Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan","institution_ids":["https://openalex.org/I43545212"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5060892525"],"corresponding_institution_ids":["https://openalex.org/I4210145364"],"apc_list":{"value":3400,"currency":"USD","value_usd":3400},"apc_paid":null,"fwci":1.3024,"has_fulltext":false,"cited_by_count":55,"citation_normalized_percentile":{"value":0.80501653,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"40","issue":"4","first_page":"393","last_page":"398"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.8428000211715698,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.8428000211715698,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.10440000146627426,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.006000000052154064,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amino-acid-imbalance","display_name":"amino acid imbalance","score":0.9940000176429749},{"id":"https://openalex.org/keywords/chronic-hepatitis","display_name":"chronic hepatitis","score":0.8479999899864197},{"id":"https://openalex.org/keywords/liver-cirrhosis","display_name":"liver cirrhosis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/branched-chain-amino-acids","display_name":"branched-chain amino acids","score":0.9710000157356262},{"id":"https://openalex.org/keywords/tyrosine","display_name":"tyrosine","score":0.8579999804496765},{"id":"https://openalex.org/keywords/liver-fibrosis-staging","display_name":"liver fibrosis staging","score":0.9509999752044678},{"id":"https://openalex.org/keywords/serum-amino-acids","display_name":"serum amino acids","score":0.7979999780654907}],"concepts":[{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.8360157012939453},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.7359893918037415},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7247943878173828},{"id":"https://openalex.org/C3020491458","wikidata":"https://www.wikidata.org/wiki/Q131742","display_name":"Chronic hepatitis","level":3,"score":0.6828406453132629},{"id":"https://openalex.org/C2777766500","wikidata":"https://www.wikidata.org/wiki/Q360841","display_name":"Liver biopsy","level":3,"score":0.6463627815246582},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.6285597085952759},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6148733496665955},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.5205605626106262},{"id":"https://openalex.org/C2776165026","wikidata":"https://www.wikidata.org/wiki/Q188017","display_name":"Tyrosine","level":2,"score":0.5050442814826965},{"id":"https://openalex.org/C2777075537","wikidata":"https://www.wikidata.org/wiki/Q929737","display_name":"Liver disease","level":2,"score":0.5002524852752686},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.4998352527618408},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.49208539724349976},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21079328656196594},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15717068314552307},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.14062389731407166},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1872-034x.2009.00614.x","doi":"https://doi.org/10.1111/j.1872-034x.2009.00614.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1872-034x.2009.00614.x","pdf_url":null,"source":{"id":"https://openalex.org/S110399111","display_name":"Hepatology Research","issn_l":"1386-6346","issn":["1386-6346","1872-034X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatology Research","raw_type":"journal-article"},{"id":"pmid:20236360","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20236360","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatology research : the official journal of the Japan Society of Hepatology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W1947984990","https://openalex.org/W1969189353","https://openalex.org/W1971689007","https://openalex.org/W1972784456","https://openalex.org/W1982049192","https://openalex.org/W1987928923","https://openalex.org/W1989000394","https://openalex.org/W1989196663","https://openalex.org/W1993089591","https://openalex.org/W2003565062","https://openalex.org/W2005526536","https://openalex.org/W2008981562","https://openalex.org/W2014702797","https://openalex.org/W2015858981","https://openalex.org/W2018459798","https://openalex.org/W2034230809","https://openalex.org/W2038832397","https://openalex.org/W2039560063","https://openalex.org/W2044989523","https://openalex.org/W2054911815","https://openalex.org/W2059986888","https://openalex.org/W2067993743","https://openalex.org/W2072139861","https://openalex.org/W2072505199","https://openalex.org/W2076644588","https://openalex.org/W2085722534","https://openalex.org/W2103778353","https://openalex.org/W2107323732","https://openalex.org/W2113988310","https://openalex.org/W2123091375","https://openalex.org/W2141880403","https://openalex.org/W2143279312","https://openalex.org/W2155403338","https://openalex.org/W2159954692","https://openalex.org/W2159966416","https://openalex.org/W2167481594","https://openalex.org/W2266583185","https://openalex.org/W2275333001","https://openalex.org/W2404087985","https://openalex.org/W4229893971","https://openalex.org/W4247209357"],"related_works":["https://openalex.org/W1987928923","https://openalex.org/W4293412928","https://openalex.org/W2418022330","https://openalex.org/W7118511463","https://openalex.org/W2378017292","https://openalex.org/W186933650","https://openalex.org/W2266583185","https://openalex.org/W2106752835","https://openalex.org/W2012862066","https://openalex.org/W4393191644"],"abstract_inverted_index":{"AIM:":[0],"The":[1,84,104,138,147],"aim":[2],"of":[3,44,78,86,106,122,140,149,158,189,202,212,220,225],"this":[4],"study":[5],"is":[6],"to":[7,75,144],"clarify":[8],"the":[9,76,93,145,153,156,217],"amino":[10,32,209],"acid":[11,210],"imbalance":[12,211],"in":[13,42,50,55,58,73,98,102,130,136,162,167,172,177,183,216,230],"patients":[14,46,87,131,190],"with":[15,23,47,62,132,193,197],"chronic":[16],"hepatitis":[17],"(CH)":[18],"as":[19,21],"well":[20],"those":[22,135],"liver":[24,69,79,221],"cirrhosis":[25],"(LC).":[26],"METHODS:":[27],"We":[28],"assayed":[29],"total":[30],"branched-chain":[31],"acids":[33],"(BCAA),":[34],"tyrosine":[35],"(Tyr)":[36],"levels":[37,72,105,139,148,157,201],"and":[38,60,100,108,120,179],"their":[39],"ratio":[40],"(BTR)":[41],"sera":[43],"101":[45],"CH":[48,99,198],"(37":[49],"fibrosis":[51,80],"stage":[52,219],"F1,":[53,168],"23":[54],"F2,":[56,173],"21":[57],"F3)":[59],"20":[61],"LC":[63,133,194],"(F4)":[64],"who":[65],"were":[66,81,110],"diagnosed":[67],"by":[68],"biopsy.":[70],"Their":[71],"relation":[74],"staging":[77],"analyzed.":[82],"RESULTS:":[83],"percentage":[85],"whose":[88],"BTR":[89,107,141],"was":[90,96,124,214,227],"less":[91],"than":[92,134],"normal":[94],"range":[95],"32.1%":[97],"75.0%":[101],"LC.":[103],"BCAA":[109,159,226],"significantly":[111,125],"lower":[112,200],"(P":[113,127],"<":[114,117,128],"0.001,":[115],"P":[116],"0.05,":[118],"respectively)":[119],"that":[121,208],"Tyr":[123,150,213],"higher":[126],"0.001)":[129],"CH.":[137],"decreased":[142],"according":[143,152],"staging.":[146],"increased":[151],"staging,":[154],"whereas":[155,223],"deceased":[160],"prominently":[161],"F4":[163,231],"(487":[164],"+/-":[165,170,175,181],"103":[166],"483":[169],"122":[171],"487":[174],"111":[176],"F3":[178],"423":[180],"94":[182],"F4).":[184],"CONCLUSION:":[185],"A":[186],"considerable":[187],"number":[188],"not":[191],"only":[192],"but":[195],"also":[196],"showed":[199],"BTR.":[203],"It":[204],"has":[205],"been":[206],"clarified":[207],"found":[215,228],"early":[218],"disease,":[222],"decrease":[224],"mainly":[229],"stage.":[232]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
