{"id":"https://openalex.org/W2170051417","doi":"https://doi.org/10.5639/gabij.2012.0101.008","title":"A review of patient perspectives on generics substitution: what are the challenges for optimal drug use","display_name":"A review of patient perspectives on generics substitution: what are the challenges for optimal drug use","publication_year":2012,"publication_date":"2012-02-15","ids":{"openalex":"https://openalex.org/W2170051417","doi":"https://doi.org/10.5639/gabij.2012.0101.008","mag":"2170051417"},"language":"en","primary_location":{"id":"doi:10.5639/gabij.2012.0101.008","doi":"https://doi.org/10.5639/gabij.2012.0101.008","is_oa":true,"landing_page_url":"https://doi.org/10.5639/gabij.2012.0101.008","pdf_url":"http://gabi-journal.net/wp-content/uploads/GJ-2012-1-p28-32-ReviewArticle-H\u00e5konsen.pdf","source":{"id":"https://openalex.org/S2764911163","display_name":"Generics and Biosimilars Initiative Journal","issn_l":"2033-6403","issn":["2033-6403","2033-6772"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-70","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Generics and Biosimilars Initiative Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://gabi-journal.net/wp-content/uploads/GJ-2012-1-p28-32-ReviewArticle-H\u00e5konsen.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011164148","display_name":"Helle H\u00e5konsen","orcid":"https://orcid.org/0000-0002-5238-1760","observed_orcids":["https://orcid.org/0000-0002-5238-1760"]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":true,"raw_author_name":"Helle H\u00e5konsen","raw_affiliation_strings":["Department of Social Pharmacy, School of Pharmacy, University of Oslo, PO Box 1068, Blindern NO-0316 Oslo, Norway,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Social Pharmacy, School of Pharmacy, University of Oslo, PO Box 1068, Blindern NO-0316 Oslo, Norway,","institution_ids":["https://openalex.org/I184942183"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058125604","display_name":"Else\u2010Lydia Toverud","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Else-Lydia Toverud","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5011164148"],"corresponding_institution_ids":["https://openalex.org/I184942183"],"apc_list":null,"apc_paid":null,"fwci":11.0993,"has_fulltext":true,"cited_by_count":52,"citation_normalized_percentile":{"value":0.9801934,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"1","issue":"1","first_page":"28","last_page":"32"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11792","display_name":"Pharmaceutical Economics and Policy","score":0.9678000211715698,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11792","display_name":"Pharmaceutical Economics and Policy","score":0.9678000211715698,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11620","display_name":"Medication Adherence and Compliance","score":0.019200000911951065,"subfield":{"id":"https://openalex.org/subfields/2714","display_name":"Family Practice"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12255","display_name":"Biosimilars and Bioanalytical Methods","score":0.002899999963119626,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/generic-drugs","display_name":"generic drugs","score":0.796999990940094},{"id":"https://openalex.org/keywords/drug-substitution","display_name":"drug substitution","score":0.7960000038146973},{"id":"https://openalex.org/keywords/patient-perspectives","display_name":"patient perspectives","score":0.902999997138977},{"id":"https://openalex.org/keywords/patient-acceptance","display_name":"patient acceptance","score":0.6970000267028809},{"id":"https://openalex.org/keywords/therapeutic-equivalence","display_name":"therapeutic equivalence","score":0.6389999985694885},{"id":"https://openalex.org/keywords/treatment-adherence","display_name":"medication adherence","score":0.7089999914169312},{"id":"https://openalex.org/keywords/medication-errors","display_name":"medication errors","score":0.7860000133514404},{"id":"https://openalex.org/keywords/patient-information","display_name":"patient information","score":0.574999988079071},{"id":"https://openalex.org/keywords/antiepileptic-drugs","display_name":"antiepileptic drugs","score":0.9350000023841858},{"id":"https://openalex.org/keywords/pharmacist-substitution","display_name":"pharmacist substitution","score":0.5410000085830688}],"concepts":[{"id":"https://openalex.org/C2778220771","wikidata":"https://www.wikidata.org/wiki/Q1522579","display_name":"Substitution (logic)","level":2,"score":0.9040632247924805},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.6853058338165283},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3634628653526306},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.35658755898475647},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.33571934700012207},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2775435447692871},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.5639/gabij.2012.0101.008","doi":"https://doi.org/10.5639/gabij.2012.0101.008","is_oa":true,"landing_page_url":"https://doi.org/10.5639/gabij.2012.0101.008","pdf_url":"http://gabi-journal.net/wp-content/uploads/GJ-2012-1-p28-32-ReviewArticle-H\u00e5konsen.pdf","source":{"id":"https://openalex.org/S2764911163","display_name":"Generics and Biosimilars Initiative Journal","issn_l":"2033-6403","issn":["2033-6403","2033-6772"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-70","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Generics and Biosimilars Initiative Journal","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.5639/gabij.2012.0101.008","doi":"https://doi.org/10.5639/gabij.2012.0101.008","is_oa":true,"landing_page_url":"https://doi.org/10.5639/gabij.2012.0101.008","pdf_url":"http://gabi-journal.net/wp-content/uploads/GJ-2012-1-p28-32-ReviewArticle-H\u00e5konsen.pdf","source":{"id":"https://openalex.org/S2764911163","display_name":"Generics and Biosimilars Initiative Journal","issn_l":"2033-6403","issn":["2033-6403","2033-6772"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-70","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Generics and Biosimilars Initiative Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2170051417.pdf","grobid_xml":"https://content.openalex.org/works/W2170051417.grobid-xml"},"referenced_works_count":32,"referenced_works":["https://openalex.org/W30449897","https://openalex.org/W53030806","https://openalex.org/W95448178","https://openalex.org/W174126088","https://openalex.org/W192004289","https://openalex.org/W1534204021","https://openalex.org/W1973881042","https://openalex.org/W1979914314","https://openalex.org/W1985694506","https://openalex.org/W1986405805","https://openalex.org/W1998680625","https://openalex.org/W1999549320","https://openalex.org/W2001245637","https://openalex.org/W2031837505","https://openalex.org/W2044839799","https://openalex.org/W2046647352","https://openalex.org/W2048705973","https://openalex.org/W2057124956","https://openalex.org/W2058409828","https://openalex.org/W2059366243","https://openalex.org/W2077617530","https://openalex.org/W2090189145","https://openalex.org/W2094028846","https://openalex.org/W2098017071","https://openalex.org/W2102901886","https://openalex.org/W2108245053","https://openalex.org/W2134546320","https://openalex.org/W2140329113","https://openalex.org/W2147345442","https://openalex.org/W2149157170","https://openalex.org/W2321991445","https://openalex.org/W2439032761"],"related_works":["https://openalex.org/W2021885962","https://openalex.org/W2395013307","https://openalex.org/W2108245053","https://openalex.org/W2563520344","https://openalex.org/W3017382675","https://openalex.org/W2322188464","https://openalex.org/W2165970450","https://openalex.org/W1484019507","https://openalex.org/W2098017071","https://openalex.org/W1995771806"],"abstract_inverted_index":{"As":[0],"the":[1,5,41,44,51,62,85,90,156,171,203,234,241],"review":[2,37,120,224],"focused":[3],"on":[4,43,61,99],"patients'":[6,45,172],"perspectives":[7,46,98],"Introduction:":[8],"With":[9],"a":[10,148,208],"few":[11],"exceptions,":[12],"generic":[13,195],"drug":[14,69,152,196],"use":[15],"has":[16],"been":[17],"promoted":[18],"in":[19,50,76,102,118],"western":[20,52,103],"countries":[21,104],"by":[22,188,233],"allowing":[23],"pharmacists":[24],"to":[25,39,124,176,249],"substitute":[26],"drugs":[27],"defined":[28],"as":[29,180],"therapeutically":[30],"equivalent":[31],"generics.The":[32],"aim":[33,86],"of":[34,47,87,126,138,158,164,183,220,236,240],"this":[35,119],"literature":[36,72,223],"is":[38,230],"summarise":[40],"research":[42,94],"generics":[48,100,165,184,228],"substitution":[49,101,166,185,229],"world":[53],"between":[54,106],"2000":[55,109],"and":[56,81,110,169,174,198,216,252],"2011":[57],"with":[58,84],"special":[59],"emphasis":[60],"challenges":[63],"these":[64],"attitudes":[65],"present":[66],"for":[67,150,211],"optimal":[68],"use.Methods:":[70],"A":[71],"search":[73],"was":[74,160,186],"undertaken":[75],"MEDLINE":[77],"(PubMed),":[78],"Embase":[79],"(Ovid),":[80],"SciVerse":[82],"Scopus":[83],"identifying":[88],"all":[89,127],"peer":[91],"reviewed,":[92],"original":[93],"articles":[95],"concerning":[96],"patient":[97],"published":[105],"1":[107,111],"January":[108],"March":[112],"2011.Results:":[113],"The":[114],"20":[115],"studies":[116,205],"included":[117],"indicate":[121],"that":[122,226],"close":[123],"one-third":[125,239],"patients":[128,139,215,242],"were":[129],"uneasy":[130],"about":[131,193,202,238],"having":[132],"their":[133,178],"drug(s)":[134],"substituted":[135],"generically.Between":[136],"8-34%":[137],"reported":[140],"poorer":[141],"effects":[142,146],"and/or":[143],"new":[144],"side":[145],"after":[147],"change-except":[149],"antiepileptic":[151],"users":[153],"from":[154],"which":[155,246],"number":[157],"reports":[159],"even":[161],"higher.Poor":[162],"awareness":[163],"caused":[167],"confusion":[168],"reduced":[170],"willingness":[173],"ability":[175],"take":[177],"medication":[179,253],"prescribed.Patients'":[181],"acceptance":[182],"influenced":[187],"age,":[189],"educational":[190],"levels,":[191],"perceptions":[192],"disease,":[194],"information,":[197],"who":[199],"informed":[200],"them":[201],"change.The":[204],"consistently":[206],"suggested":[207],"continuing":[209],"need":[210],"information":[212],"directed":[213],"at":[214],"an":[217],"increased":[218],"involvement":[219],"physicians.Conclusion:":[221],"This":[222],"suggests":[225],"although":[227],"well":[231],"accepted":[232],"majority":[235],"patients,":[237],"report":[243],"negative":[244],"experiences":[245],"may":[247],"lead":[248],"poor":[250],"adherence":[251],"errors.":[254]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}