{"id":"https://openalex.org/W2169952501","doi":null,"title":"The neuroanatomical expression profile of novel membrane proteins. The effect of macronutrients on gene expression.","display_name":"The neuroanatomical expression profile of novel membrane proteins. The effect of macronutrients on gene expression.","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W2169952501","mag":"2169952501"},"language":"en","primary_location":{"id":"pmh:oai:DiVA.org:mdh-1105","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-1105","pdf_url":null,"source":{"id":"https://openalex.org/S4306400653","display_name":"Diva portal (Dalarna University Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/bachelorThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-1105","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065484939","display_name":"Jennie Malmberg","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jennie Malmberg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5065484939"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11584","display_name":"Biochemical Analysis and Sensing Techniques","score":0.006300000008195639,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13984","display_name":"Nutrition, Genetics, and Disease","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.9950000047683716},{"id":"https://openalex.org/keywords/food-intake-regulation","display_name":"food intake regulation","score":0.8759999871253967},{"id":"https://openalex.org/keywords/macronutrients","display_name":"macronutrients","score":0.7649999856948853},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.8270000219345093},{"id":"https://openalex.org/keywords/satiety-signals","display_name":"satiety signals","score":0.7889999747276306},{"id":"https://openalex.org/keywords/food-preferences","display_name":"food preferences","score":0.5860000252723694},{"id":"https://openalex.org/keywords/leucine","display_name":"leucine","score":0.8669999837875366},{"id":"https://openalex.org/keywords/sucrose","display_name":"sucrose","score":0.6980000138282776},{"id":"https://openalex.org/keywords/fat-intake","display_name":"dietary fat intake","score":0.5519999861717224},{"id":"https://openalex.org/keywords/hypothalamus","display_name":"hypothalamus","score":0.8920000195503235},{"id":"https://openalex.org/keywords/brainstem","display_name":"brainstem","score":0.9850000143051147},{"id":"https://openalex.org/keywords/neuroanatomy","display_name":"neuroanatomy","score":0.4909999966621399},{"id":"https://openalex.org/keywords/feeding-behavior","display_name":"feeding behavior","score":0.4339999854564667},{"id":"https://openalex.org/keywords/mice","display_name":"mice","score":0.3230000138282776},{"id":"https://openalex.org/keywords/energy-homeostasis","display_name":"energy homeostasis","score":0.527999997138977},{"id":"https://openalex.org/keywords/appetite-regulation","display_name":"appetite regulation","score":0.3109999895095825},{"id":"https://openalex.org/keywords/immunohistochemistry","display_name":"immunohistochemistry","score":0.5799999833106995},{"id":"https://openalex.org/keywords/rt-pcr","display_name":"RT-PCR","score":0.9089999794960022},{"id":"https://openalex.org/keywords/western-blot","display_name":"Western blot","score":0.5929999947547913},{"id":"https://openalex.org/keywords/immunofluorescence","display_name":"immunofluorescence","score":0.6169999837875366}],"concepts":[{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.6068459153175354},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.6060192584991455},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.508415162563324},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.4885302782058716},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4660514295101166},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4286019206047058},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.34170669317245483},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.3392256200313568},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.28945544362068176},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2878546416759491},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.28278499841690063},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.1269356608390808},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:DiVA.org:mdh-1105","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-1105","pdf_url":null,"source":{"id":"https://openalex.org/S4306400653","display_name":"Diva portal (Dalarna University Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/bachelorThesis"},{"id":"mag:2169952501","doi":null,"is_oa":false,"landing_page_url":"http://diva-portal.org/smash/get/diva2:25505/fulltext01.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:DiVA.org:mdh-1105","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-1105","pdf_url":null,"source":{"id":"https://openalex.org/S4306400653","display_name":"Diva portal (Dalarna University Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/bachelorThesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.7246000170707703,"id":"https://metadata.un.org/sdg/3"},{"display_name":"Zero hunger","score":0.6735000014305115,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1577577364","https://openalex.org/W1655590724","https://openalex.org/W1970577797","https://openalex.org/W1973924208","https://openalex.org/W1978605242","https://openalex.org/W1980604504","https://openalex.org/W1983559246","https://openalex.org/W1988432691","https://openalex.org/W1994091958","https://openalex.org/W2007064781","https://openalex.org/W2017570416","https://openalex.org/W2067152194","https://openalex.org/W2092625960","https://openalex.org/W2095522890","https://openalex.org/W2124738442","https://openalex.org/W2138559331","https://openalex.org/W2169494000"],"related_works":["https://openalex.org/W82140966","https://openalex.org/W2037031103","https://openalex.org/W2883213315","https://openalex.org/W2128837130","https://openalex.org/W1982008547","https://openalex.org/W149358180","https://openalex.org/W1968235939","https://openalex.org/W2725762478","https://openalex.org/W2099784565","https://openalex.org/W71856641"],"abstract_inverted_index":{"Worldwide":[0],"obesity":[1,11],"is":[2,26,75,83,250,349,427,431,468],"an":[3,45,268,407,479],"increasing":[4],"problem.":[5],"Apart":[6],"from":[7,440],"the":[8,14,22,29,48,51,63,72,78,91,96,103,107,114,121,130,170,173,180,202,226,261,265,279,290,296,316,331,337,356,366,410,416,444,448,463,474,483,491,499],"fact":[9],"that":[10,80,98,140,204,462],"greatly":[12],"impairs":[13],"health,":[15],"quality":[16],"and":[17,67,89,118,156,200,312,386,452,477,496],"length":[18],"of":[19,47,62,106,129,132,151,172,190,218,224,267,292,298,318,339,353,365,374,395,438,443,455,485,501],"life":[20],"for":[21,166,208,233,238,363],"affected":[23,489],"individuals,":[24],"it":[25,343],"also":[27,210,460],"has":[28,273,402,478],"potential":[30],"to":[31,258,277,307,310,329,336,345,370,379,405,424],"become":[32],"a":[33,38,59,146,186,206,212,230,301,308,350],"major":[34],"socioeconomic":[35],"problem":[36],"in":[37,138,145,158,185,193,198,215,235,240,285,387,391,418],"near":[39],"future.":[40],"However":[41],"preventive":[42],"actions":[43],"require":[44],"understanding":[46,61],"cause.":[49],"Before":[50],"psychological":[52],"influence":[53,95],"on":[54,247,355,383,409,482],"eating":[55],"can":[56,493],"be":[57,154,264,371,494],"evaluated":[58,155],"profound":[60],"biological":[64],"regulatory":[65,175,333,412],"system":[66,176],"how":[68,330],"this":[69,244,304],"interacts":[70],"with":[71,160,287,320],"food":[73,81,88,92,110,117,167,196,289,314,319],"consumed":[74],"required.":[76],"On":[77],"assumption":[79],"consumption":[82],"regulated":[84],"by":[85,177,415,435,453,490],"interplay":[86,115],"between":[87,116,182],"genes,":[90],"itself":[93],"may":[94,245,263],"genes":[97,108,367],"regulate":[99],"consumption,":[100],"hence":[101],"change":[102,417],"expression":[104,347,358,420],"levels":[105],"regulating":[109],"intake.":[111,282],"To":[112],"evaluate":[113],"gene":[119,346,357,419],"expression,":[120],"project":[122],"contained":[123],"several":[124],"parts,":[125],"reflecting":[126],"different":[127,441],"aspects":[128],"area":[131],"research.":[133],"The":[134,149,163,242,324,360,393,422,458,487],"feeding":[135,174,382,411],"studies":[136,249,255],"had":[137],"common":[139,361],"they":[141],"were":[142],"initial":[143],"trials":[144],"larger":[147],"project.":[148],"results":[150,227],"these":[152],"will":[153],"used":[157],"combination":[159,286],"further":[161,254],"studies.":[162],"mice":[164],"typed":[165],"preference":[168,207,231,309],"illustrate":[169],"complexity":[171],"pointing":[178],"out":[179],"differences":[181],"individuals":[183],"even":[184],"relatively":[187],"small":[188],"group":[189],"animals.":[191],"Mice":[192],"general":[194],"like":[195],"high":[197],"fat":[199,401],"here":[201],"animals":[203],"showed":[205,211,404],"sugar":[209,399],"significant":[213,351],"increase":[214],"their":[216],"intake":[217,297,338,394],"chow.":[219,299],"Since":[220],"chow":[221],"consists":[222],"mainly":[223],"carbohydrates":[225,239],"might":[228],"indicate":[229],"not":[232],"sucrose":[234,390],"particular":[236],"but":[237],"general.":[241],"effect":[243,352,408],"have":[246,406],"other":[248],"still":[251],"unclear":[252],"as":[253,377,398,447],"are":[256],"needed":[257],"determine":[259],"whether":[260],"difference":[262],"result":[266],"innate":[269],"genetic":[270],"difference.":[271],"Leucine":[272,293],"been":[274,403],"previously":[275],"shown":[276,433],"reduce":[278],"total":[280],"caloric":[281],"When":[283,342],"given":[284],"palatable":[288,384],"addition":[291],"primarily":[294],"reduced":[295],"From":[300],"dietary":[302],"perspective":[303],"would":[305],"translate":[306],"sweets":[311],"fast":[313],"at":[315],"expense":[317],"more":[321],"nutritious":[322],"content.":[323],"RT-PCR":[325],"analysis\u2019s":[326],"gives":[327],"clues":[328],"energy":[332],"circuitry":[334],"responds":[335],"selected":[340,456],"macronutrients.":[341],"comes":[344],"there":[348],"macronutrients":[354,396,426],"levels.":[359,421],"theme":[362],"many":[364,388],"tested":[368],"seems":[369],"down":[372],"regulation":[373],"satiety":[375],"signals,":[376],"if":[378],"support":[380],"over":[381,473],"diets":[385],"cases":[389],"particular.":[392],"such":[397,446],"or":[400,450],"circuitry,":[413],"demonstrated":[414],"response":[423],"said":[425],"site":[428],"specific":[429],"which":[430],"clearly":[432],"both":[434],"RTPCR":[436],"analysis":[437],"samples":[439],"parts":[442],"brain,":[445],"brainstem":[449],"hypothalamus,":[451],"immunohistochemistry":[454,459],"areas.":[457],"confirms":[461],"novel":[464],"Oxytocin":[465],"receptor-antagonist,":[466],"who":[467],"injected":[469],"IP,":[470],"actually":[471],"passes":[472],"blood-brain":[475],"barrier":[476],"actual":[480],"affect":[481],"regions":[484],"interest.":[486],"areas":[488],"antagonist":[492],"visualized":[495],"identified":[497],"through":[498],"staining":[500],"active":[502],"sites.":[503]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}