{"id":"https://openalex.org/W2169873170","doi":"https://doi.org/10.1152/ajpheart.00958.2008","title":"Effect of stellate ganglionectomy on basal cardiovascular function and responses to \u03b21-adrenoceptor blockade in the rat","display_name":"Effect of stellate ganglionectomy on basal cardiovascular function and responses to \u03b21-adrenoceptor blockade in the rat","publication_year":2008,"publication_date":"2008-10-18","ids":{"openalex":"https://openalex.org/W2169873170","doi":"https://doi.org/10.1152/ajpheart.00958.2008","mag":"2169873170","pmid":"https://pubmed.ncbi.nlm.nih.gov/18931026","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2614551"},"language":"en","primary_location":{"id":"doi:10.1152/ajpheart.00958.2008","doi":"https://doi.org/10.1152/ajpheart.00958.2008","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpheart.00958.2008","pdf_url":null,"source":{"id":"https://openalex.org/S87338489","display_name":"American Journal of Physiology-Heart and Circulatory Physiology","issn_l":"0363-6135","issn":["0363-6135","1522-1539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Heart and Circulatory Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2614551","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016153798","display_name":"Misa Yoshimoto","orcid":"https://orcid.org/0009-0007-9483-4805","observed_orcids":["https://orcid.org/0009-0007-9483-4805"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Misa Yoshimoto","raw_affiliation_strings":["Department of Integrative Biology and Physiology, University of Minneapolis, Minneapolis, MN 55455, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Integrative Biology and Physiology, University of Minneapolis, Minneapolis, MN 55455, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022732945","display_name":"Erica A. Wehrwein","orcid":"https://orcid.org/0000-0002-5197-2147","observed_orcids":["https://orcid.org/0000-0002-5197-2147"]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Erica A. Wehrwein","raw_affiliation_strings":["","\u2002Michigan State University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"\u2002Michigan State University","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002671896","display_name":"Martin Novotn\u00fd","orcid":"https://orcid.org/0000-0001-6446-7257","observed_orcids":["https://orcid.org/0000-0001-6446-7257"]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin Novotny","raw_affiliation_strings":["","\u2002Michigan State University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"\u2002Michigan State University","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073641507","display_name":"Greg M. Swain","orcid":"https://orcid.org/0000-0001-6498-8351","observed_orcids":["https://orcid.org/0000-0001-6498-8351"]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Greg M. Swain","raw_affiliation_strings":["","\u2002Michigan State University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"\u2002Michigan State University","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020174556","display_name":"David L. Kreulen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David L. Kreulen","raw_affiliation_strings":["","\u2002Michigan State University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"\u2002Michigan State University","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091827299","display_name":"John W. Osborn","orcid":"https://orcid.org/0000-0002-8109-1578","observed_orcids":["https://orcid.org/0000-0002-8109-1578"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John W. Osborn","raw_affiliation_strings":["","Integrative Biology and Physiology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Integrative Biology and Physiology","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.1815,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.88951007,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"295","issue":"6","first_page":"H2447","last_page":"H2454"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.7153000235557556,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.7153000235557556,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.2272000014781952,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.017899999395012856,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/stellate-ganglionectomy","display_name":"stellate ganglionectomy","score":0.996999979019165},{"id":"https://openalex.org/keywords/cardiac-sympathetic-denervation","display_name":"cardiac sympathetic denervation","score":0.8100000023841858},{"id":"https://openalex.org/keywords/beta1-adrenoceptor-blockade","display_name":"beta1-adrenoceptor blockade","score":0.921999990940094},{"id":"https://openalex.org/keywords/atenolol","display_name":"atenolol","score":0.9980000257492065},{"id":"https://openalex.org/keywords/mean-arterial-pressure","display_name":"mean arterial pressure","score":0.8450000286102295},{"id":"https://openalex.org/keywords/heart-rate","display_name":"heart rate","score":0.9940000176429749},{"id":"https://openalex.org/keywords/cardiac-sympathetic-nerve-activity","display_name":"cardiac sympathetic activity","score":0.734000027179718},{"id":"https://openalex.org/keywords/cardiac-catecholamines","display_name":"cardiac catecholamines","score":0.8730000257492065},{"id":"https://openalex.org/keywords/sympathetic-nervous-system","display_name":"sympathetic nervous system","score":0.5090000033378601},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.5339999794960022},{"id":"https://openalex.org/keywords/bradycardia","display_name":"bradycardia","score":0.7129999995231628}],"concepts":[{"id":"https://openalex.org/C2776650652","wikidata":"https://www.wikidata.org/wiki/Q5521150","display_name":"Ganglionectomy","level":3,"score":0.8756309151649475},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7968131303787231},{"id":"https://openalex.org/C2776525901","wikidata":"https://www.wikidata.org/wiki/Q411325","display_name":"Atenolol","level":3,"score":0.7554125785827637},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.5775965452194214},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.5706697106361389},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5600778460502625},{"id":"https://openalex.org/C2779190097","wikidata":"https://www.wikidata.org/wiki/Q6128790","display_name":"Sympathectomy","level":2,"score":0.554260790348053},{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.49781322479248047},{"id":"https://openalex.org/C2776452961","wikidata":"https://www.wikidata.org/wiki/Q1940733","display_name":"Mean arterial pressure","level":4,"score":0.49577245116233826},{"id":"https://openalex.org/C2777495988","wikidata":"https://www.wikidata.org/wiki/Q217111","display_name":"Bradycardia","level":4,"score":0.4951077997684479},{"id":"https://openalex.org/C2776533406","wikidata":"https://www.wikidata.org/wiki/Q187215","display_name":"Sympathetic nervous system","level":3,"score":0.4884111285209656},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.48184072971343994},{"id":"https://openalex.org/C191237925","wikidata":"https://www.wikidata.org/wiki/Q808725","display_name":"Baroreflex","level":4,"score":0.4724348485469818},{"id":"https://openalex.org/C2776805190","wikidata":"https://www.wikidata.org/wiki/Q1187030","display_name":"Denervation","level":2,"score":0.46393755078315735},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4571109414100647},{"id":"https://openalex.org/C111566952","wikidata":"https://www.wikidata.org/wiki/Q1303462","display_name":"Cardiac function curve","level":3,"score":0.4119083285331726},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.2628573179244995},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000319","descriptor_name":"Adrenergic beta-Antagonists","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001262","descriptor_name":"Atenolol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002395","descriptor_name":"Catecholamines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004326","descriptor_name":"Drinking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":true},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013233","descriptor_name":"Stellate Ganglion","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D013564","descriptor_name":"Sympathetic Nervous System","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013564","descriptor_name":"Sympathetic Nervous System","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013686","descriptor_name":"Telemetry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015171","descriptor_name":"Ganglionectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015716","descriptor_name":"Electrocardiography, Ambulatory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018342","descriptor_name":"Receptors, Adrenergic, beta-1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018660","descriptor_name":"Blood Pressure Monitoring, Ambulatory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058671","descriptor_name":"Adrenergic beta-1 Receptor Antagonists","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1152/ajpheart.00958.2008","doi":"https://doi.org/10.1152/ajpheart.00958.2008","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpheart.00958.2008","pdf_url":null,"source":{"id":"https://openalex.org/S87338489","display_name":"American Journal of Physiology-Heart and Circulatory Physiology","issn_l":"0363-6135","issn":["0363-6135","1522-1539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Heart and Circulatory Physiology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2614551","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2614551","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Physiol Heart Circ Physiol","raw_type":"Text"},{"id":"pmid:18931026","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18931026","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of physiology. Heart and circulatory physiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2614551","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2614551","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Physiol Heart Circ Physiol","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5623581239","display_name":"Long-Term Neural Determinants of Cardiovascular Diseases","funder_award_id":"R01HL076312","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5665044768","display_name":null,"funder_award_id":"R01 HL-64176","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8747606191","display_name":"Neural Mechanisms of Long-Term Cardiovascular Control","funder_award_id":"R01HL064178","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W124217991","https://openalex.org/W237000831","https://openalex.org/W254934953","https://openalex.org/W1802552881","https://openalex.org/W1964562856","https://openalex.org/W1965374914","https://openalex.org/W1973799769","https://openalex.org/W1988334159","https://openalex.org/W1995795243","https://openalex.org/W1996707480","https://openalex.org/W1996819524","https://openalex.org/W2013354239","https://openalex.org/W2027682425","https://openalex.org/W2035518483","https://openalex.org/W2055924815","https://openalex.org/W2064071650","https://openalex.org/W2076073800","https://openalex.org/W2083092596","https://openalex.org/W2108120019","https://openalex.org/W2108684086","https://openalex.org/W2108929268","https://openalex.org/W2109625017","https://openalex.org/W2113627667","https://openalex.org/W2114056678","https://openalex.org/W2120894162","https://openalex.org/W2129695314","https://openalex.org/W2130953449","https://openalex.org/W2133855071","https://openalex.org/W2140626980","https://openalex.org/W2148473247","https://openalex.org/W2160513558","https://openalex.org/W2163577718","https://openalex.org/W2225494317","https://openalex.org/W2397796393","https://openalex.org/W2406230482","https://openalex.org/W2416733045","https://openalex.org/W2557007424"],"related_works":["https://openalex.org/W2288508217","https://openalex.org/W2158993421","https://openalex.org/W2900015466","https://openalex.org/W2292720107","https://openalex.org/W4310554007","https://openalex.org/W4378674776","https://openalex.org/W4366817866","https://openalex.org/W2414598344","https://openalex.org/W2562324550","https://openalex.org/W2055548876"],"abstract_inverted_index":{"Cardiac":[0],"sympathetic":[1,23,47,76,92,244,262,276],"nerve":[2,24],"activity":[3,25],"is":[4,252],"an":[5],"important":[6],"short-term":[7],"controller":[8],"of":[9,42,45,52,78,90,97,113,127,193,225,228,238,260,267,286],"cardiac":[10,22,34,46,91,229,233,261,268,275],"function":[11],"and":[12,33,102,106,129,188,201],"arterial":[13,99],"pressure.":[14],"Studies":[15],"also":[16],"suggest":[17,273],"that":[18,249,274],"long-term":[19,83],"increases":[20],"in":[21,36,49,199,206,210,220,231,281,294],"may":[26],"contribute":[27],"to":[28,67,72,109,140,256,292],"hypertension,":[29],"coronary":[30],"artery":[31],"disease,":[32],"remodeling":[35],"heart":[37,81,103],"failure.":[38],"However,":[39],"our":[40],"understanding":[41],"the":[43,75,79,88,107,136,157,226,236,239,258,265,283,289],"role":[44],"nerves":[48,77,263,277],"chronic":[50,111],"models":[51],"cardiovascular":[53,84],"disease":[54],"has":[55],"been":[56],"limited":[57],"by":[58,166],"inadequate":[59],"experimental":[60],"approaches.":[61],"The":[62,223],"present":[63],"study":[64,240,247,257],"was":[65],"conducted":[66],"develop":[68],"a":[69,110,115,132,167,172,207,215,242,253],"surgical":[70],"method":[71,255],"surgically":[73],"denervate":[74],"rat":[80],"for":[82,124,162],"studies.":[85],"We":[86],"characterized":[87],"effect":[89,178],"denervation":[93],"on":[94,179,218,264],"basal":[95,180,284],"levels":[96],"mean":[98],"pressure":[100],"(MAP)":[101],"rate":[104],"(HR)":[105],"responses":[108],"administration":[112],"atenolol,":[114],"beta1-adrenoceptor":[116],"antagonist.":[117],"Rats":[118],"were":[119,138,159],"instrumented":[120],"with":[121,186],"telemetry":[122],"transmitters":[123],"continuous":[125],"recording":[126],"MAP":[128,181,197,287],"HR.":[130],"After":[131],"4-day":[133],"baseline":[134,187],"period,":[135],"rats":[137,158,212],"subjected":[139],"bilateral":[141,250],"stellate":[142],"ganglionectomy":[143],"(SGX;":[144],"n=9)":[145],"or":[146,155,288],"sham":[147],"surgery":[148],"(Sham;":[149],"n=8).":[150],"Seven":[151],"days":[152,192],"following":[153],"SGX":[154,175,200,221,251],"Sham,":[156],"administered":[160],"atenolol":[161,194,293],"5":[163],"days,":[164],"followed":[165],"7-day":[168],"recovery":[169],"period.":[170],"Following":[171],"transient":[173],"decrease,":[174],"had":[176,214],"no":[177],"but":[182,213],"decreased":[183,196],"HR":[184,219],"compared":[185],"Sham":[189,202,211],"rats.":[190,203,222,297],"Five":[191],"treatment":[195],"similarly":[198],"Atenolol":[204],"resulted":[205],"marked":[208],"bradycardia":[209],"neglible":[216],"effects":[217],"measurement":[224],"content":[227],"catecholamines":[230],"all":[232],"chambers":[234],"at":[235],"end":[237],"verified":[241],"successful":[243],"denervation.":[245],"This":[246],"confirms":[248],"useful":[254],"contribution":[259],"regulation":[266],"function.":[269],"Moreover,":[270],"these":[271],"results":[272],"are":[278],"relatively":[279],"unimportant":[280],"maintaining":[282],"level":[285],"depressor":[290],"response":[291],"conscious,":[295],"unrestrained":[296]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}